48
Views
4
CrossRef citations to date
0
Altmetric
Original Article

CYP17 polymorphism and hot flushes in postmenopausal women

, , , , , , , & show all
Pages 404-408 | Received 03 Jun 2008, Accepted 15 Jul 2008, Published online: 03 Jul 2009

References

  • Takeo C, Negishi E, Nakajima A, et al. Association of cytosine-adenine repeat polymorphism of the estrogen receptor-beta gene with menopausal symptoms. Gend Med 2005; 2: 96–105
  • Kronenberg F. Hot flashes: epidemiology and physiology. Ann NY Acad Sci 1990; 592: 52–86
  • Steiner M, Dunn E, Born L. Hormones and mood: from menarche to menopause and beyond. J Affect Disord 2003; 74: 67–83
  • Stocco D, Clark B. Regulation of the acute production of steroids in steroidogenic cells. Endocr Rev 1996; 17: 221–244
  • Dunning A, Dowsett M, Healey C, et al. Polymorphisms associated with circulating sex hormone levels in postmenopausal women. J Natl Cancer Inst 2004; 96: 936–945
  • Picado-Leonard J, Miller W. Cloning and sequence of the human gene for P450c17 (steroid 17 alpha-hydroxiylase/17,20 lyase): similarity with the gene for P450c21. DNA 1987; 6: 439–448
  • Sharp L, Cardy A, Cotton S, Little J. CYP17 gene polymorphisms: prevalence and associations with hormone levels and related factors. AHuGE Review. Am J Epidemiol 2004; 160: 729–740
  • Haiman C, Hankinson S, Spiegelman D, et al. The relationship between a polymorphism in CYP17 with plasma hormone levels and breast cancer. Cancer Res 1999; 59: 1015–1020
  • Nagle C, Chenevix-Trench G, Webb P, Spurdle A. Ovarian cancer survival and polymorphisms in hormone and DNA repair pathway genes. Cancer Lett 2007; 18: 96–104
  • Campbell P, Edwards L, Mclaughlin J, Green J, Younghusband H, Woods M. Cytochrome P450 17A1 and catechol O-methyltransferase polymorphisms and age at Lynch syndrome colon cancer onset in Newfoundland. Clin Cancer Res 2007; 13: 3783–3788
  • Hamada A, Danesi R, Price D, et al. Association of a CYP17 polymorphism with overall survival in Caucasian patients with androgen-independent prostate cancer. Urology 2007; 70: 217–220
  • Gaudet M, Lacey J, Lissowska J, et al. Genetic variation in CYP17 and endometrial cancer risk. Hum Genet 2008; 123: 155–162
  • Chen Y, Gammon M, Teitelbaum S, et al. Estrogen-biosynthesis gene CYP17 and its interactions with reproductive, hormonal and lifestyle factors in breast cancer risk: results from the Long Island Breast Cancer Study Project. Carcinogenesis 2008; 29: 766–771
  • Carey A, Waterworth D, Patel K, et al. Polycystic ovaries and premature male pattern baldness are associated with one allele of the steroid metabolism gene CYP17. Hum Mol Genet 1994; 3: 1873–1876
  • Feigelson H, Mckean-Cowdin R, Pike M, et al. Cytochrome P450c17alpha gene (CYP17) polymorphism predicts use of hormone replacement therapy. Cancer Res 1999; 59: 3908–3910
  • Freeman E, Sherif K. Prevalence of hot flushes and night sweats around the world: a systematic review. Climacteric 2007; 10: 197–214
  • Overlie I, Moen M, Holte A, Finset A. Androgens and estrogens in relation to hot flushes during the menopausal transition. Maturitas 2002; 41: 69–77
  • Guthrie J, Dennerstein L, Taffe J, Lehert P, Burger H. Hot flushes during the menopause transition: a longitudinal study in Australian-born women. Menopause 2005; 12: 460–467
  • Randolph J, Sowers M, Bondarenko I, et al. The relationship of longitudinal change in reproductive hormones and vasomotor symptoms during the menopausal transition. J Clin Endocrinol Metab 2005; 90: 6106–6112
  • Maclennan A, Lester S, Moore V. Oral estrogen replacement therapy versus placebo for hot flushes: a systematic review. Climacteric 2001; 4: 58–74
  • Nelson H. Commonly used types of postmenopausal estrogen for treatment of hot flashes: scientific review. JAMA 2004; 291: 1610–1620
  • Simpson E, Clyne C, Rubin G, et al. Aromatase – a brief overview. Annu Rev Physiol 2002; 64: 93–127
  • Tempfer C, Schneeberger C, Huber J. Applications of polymorphisms and pharmacogenomics in obstetrics and gynecology. Pharmacogenomics 2004; 5: 57–65
  • Mitchell E, Farin F, Stapleton P, et al. Association of estrogen-related polymorphisms with age at menarche, age at final menstrual period, and stages of the menopausal transition. Menopause 2008; 15: 105–111
  • Feigelson H, Shames L, Pike M, Coetzee G, Stanczyk F, Henderson B. Cytochrome P450c17{alpha} gene (CYP17) polymorphism is associated with serum oestrogen and progesterone concentration. Cancer Res 1998; 58: 585–587
  • Haiman C, Hankinson S, Spiegelman D, et al. The relationship between a polymorphism in CYP17 with plasma hormone levels and breast cancer. Cancer Res 1999; 59: 1015–1020
  • Visvanathan K, Gallicchio L, Schilling C, et al. Cytochrome gene polymorphisms, serum estrogens, and hot flushes in midlife women. Obstet Gynecol 2005; 106: 1372–1381

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.