Predictors of malignancy in endometrial polyps: study of 421 women with postmenopausal bleeding

References

• American Association of Gynecologic Laparoscopists. AAGL practice report: practice guidelines for the diagnosis and management of endometrial polyps. J Minim Invasive Gynecol 2012;19:3–10
   PubMed Web of Science ®Google Scholar
• Sant'Ana de Almeida EC, Nogueira AA, Candido dos Reis FJ, et al. Immunohistochemical expression of estrogen and progesterone receptors in endometrial polyps and adjacent endometrium in postmenopausal women. Maturitas 2004;49:229–33
   PubMed Web of Science ®Google Scholar
• Epstein E, Ramirez A, Skoog L, et al. Transvaginal sonography, saline contrast sonohysterography and hysteroscopy for the investigation of women with postmenopausal bleeding and endometrium >5 mm. Ultrasound Obstet Gynecol 2001;18:157–62
   PubMed Web of Science ®Google Scholar
• Lee SC, Kaunitz AM, Sanchez-Ramos L, et al. The oncogenic potential of endometrial polyps: a systematic review and meta-analysis. Obstet Gynecol 2010;116:1197–205
   PubMed Web of Science ®Google Scholar
• Lieng M, Istre O, Qvigstad E. Treatment of endometrial polyps: a systematic review. Acta Obstet Gynecol Scand 2010;89:992–1002
   PubMed Web of Science ®Google Scholar
• Dreisler E, Stampe Sorensen S, Ibsen PH, et al. Prevalence of endometrial polyps and abnormal uterine bleeding in a Danish population aged 20-74 years. Ultrasound Obstet Gynecol 2009;33:102–8
   PubMed Web of Science ®Google Scholar
• Anastasiadis PG, Koutlaki NG, Skaphida PG, et al. Endometrial polyps: prevalence, detection, and malignant potential in women with abnormal uterine bleeding. Eur J Gynaecol Oncol 2000;21:180–3
   PubMed Web of Science ®Google Scholar
• Domingues AP, Lopes H, Dias I, et al. Endometrial polyps in postmenopausal women. Acta Obstet Gynecol Scand 2009;88:618–20
   PubMed Web of Science ®Google Scholar
• Oguz S, Sargin A, Kelekci S, et al. The role of hormone replacement therapy in endometrial polyp formation. Maturitas 2005;50:231–6
   PubMed Web of Science ®Google Scholar
• Exacoustos C, Zupi E, Cangi B, et al. Endometrial evaluation in postmenopausal breast cancer patients receiving tamoxifen: an ultrasound, color flow Doppler, hysteroscopic and histological study. Ultrasound Obstet Gynecol 1995;6:435–42
   PubMed Web of Science ®Google Scholar
• Hann LE, Gretz EM, Bach AM, et al. Sonohysterography for evaluation of the endometrium in women treated with tamoxifen. AJR Am J Roentgenol 2001;177:337–42
   PubMed Web of Science ®Google Scholar
• Bakour SH, Khan KS, Gupta JK. The risk of premalignant and malignant pathology in endometrial polyps. Acta Obstet Gynecol Scand 2000;79:317–20
   PubMed Web of Science ®Google Scholar
• Antunes A, Jr, Costa-Paiva L, Arthuso M, et al. Endometrial polyps in pre- and postmenopausal women: factors associated with malignancy. Maturitas 2007;57:415–21
   PubMed Web of Science ®Google Scholar
• Baiocchi G, Manci N, Pazzaglia M, et al. Malignancy in endometrial polyps: a 12-year experience. Am J Obstet Gynecol 2009;201:462 e1–4
   Web of Science ®Google Scholar
• Ben-Arie A, Goldchmit C, Laviv Y, et al. The malignant potential of endometrial polyps. Eur J Obstet Gynecol Reprod Biol 2004;115:206–10
   PubMed Web of Science ®Google Scholar
• Ferrazzi E, Zupi E, Leone FP, et al. How often are endometrial polyps malignant in asymptomatic postmenopausal women? A multicenter study. Am J Obstet Gynecol 2009;200:235 e1–6
   PubMed Web of Science ®Google Scholar
• Timmermans A, Veersema S, van Kerkvoorde TC, et al. Should endometrial polyps be removed in patients with postmenopausal bleeding?: an assessment of study designs and report of a failed randomised controlled trial (ISRCTN73825127). BJOG 2009;116:1391–5
   PubMed Web of Science ®Google Scholar
• Leone FP, Timmerman D, Bourne T, et al. Terms, definitions and measurements to describe the sonographic features of the endometrium and intrauterine lesions: a consensus opinion from the International Endometrial Tumor Analysis (IETA) group. Ultrasound Obstet Gynecol 2010;35:103–12
   PubMed Web of Science ®Google Scholar
• Ewies AA, Musonda P. Managing postmenopausal bleeding revisited: what is the best first line investigation and who should be seen within 2 weeks? A cross-sectional study of 326 women. Eur J Obstet Gynecol Reprod Biol 2010;153:67–71
   PubMed Web of Science ®Google Scholar
• Bergeron C, Nogales FF, Masseroli M, et al. A multicentric European study testing the reproducibility of the WHO classification of endometrial hyperplasia with a proposal of a simplified working classification for biopsy and curettage specimens. Am J Surg Pathol 1999;23:1102–8
   PubMed Web of Science ®Google Scholar
• Gallos ID, Ganesan R, Gupta JK. Prediction of regression and relapse of endometrial hyperplasia with conservative therapy. Obstet Gynecol 2013;121:1165–71
   PubMed Web of Science ®Google Scholar
• Lacey JV, Jr, Sherman ME, Rush BB, et al. Absolute risk of endometrial carcinoma during 20-year follow-up among women with endometrial hyperplasia. J Clin Oncol 2010;28:788–92
   PubMed Web of Science ®Google Scholar
• Royal College of Obstetricians and Gynaecologists (RCOG). Management of Endometrial Hyperplasia Green-Top Guideline No. 67; 2016 [28 August 2017]. Available from: https://www.rcog.org.uk
   Google Scholar
• National Health System (NHS) Health Research Authority (HRA). Governance Arrangements for Research Ethics Committees (GAfREC): UK Health Departments; 2011 [28 August 2017]. Available from: http://www.hra.nhs.uk
   Google Scholar
• University College of London (UCL) Research Ethics Committe. Exemptions 2015 [28 August 2017]. Available from: https://ethics.grad.ucl.ac.uk/exemptions.php
   Google Scholar
• Indrayan A. Search for the best threshold of continuous test: ROC curve. Medical Biostatistics. 3rd ed. Boca Raton, FL: CRC Press; 2013:297
   Google Scholar
• Lieng M, Qvigstad E, Sandvik L, et al. Hysteroscopic resection of symptomatic and asymptomatic endometrial polyps. J Minim Invasive Gynecol 2007;14:189–94
   PubMed Web of Science ®Google Scholar
• Wang JH, Zhao J, Lin J. Opportunities and risk factors for premalignant and malignant transformation of endometrial polyps: management strategies. J Minim Invasive Gynecol 2010;17:53–8
   PubMed Web of Science ®Google Scholar
• Gregoriou O, Konidaris S, Vrachnis N, et al. Clinical parameters linked with malignancy in endometrial polyps. Climacteric 2009;12:454–8
   PubMed Web of Science ®Google Scholar
• Savelli L, De Iaco P, Santini D, et al. Histopathologic features and risk factors for benignity, hyperplasia, and cancer in endometrial polyps. Am J Obstet Gynecol 2003;188:927–31
   PubMed Web of Science ®Google Scholar
• Orvieto R, Bar-Hava I, Dicker D, et al. Endometrial polyps during menopause: characterization and significance. Acta Obstet Gynecol Scand 1999;78:883–6
   PubMed Web of Science ®Google Scholar
• Martinez MA, Jou P, Nonell R, et al. Endometrial polyps: risk of transformation and clinico-anatomic correlation [10.1016/S0304-5013(04)76044-6]. Prog Obstet Ginecol 2004;47:506–10
   Google Scholar
• Nathani F, Clark TJ. Uterine polypectomy in the management of abnormal uterine bleeding: a systematic review. J Minim Invasive Gynecol 2006;13:260–8
   PubMed Web of Science ®Google Scholar
• Lieng M, Istre O, Sandvik L, et al. Prevalence, 1-year regression rate, and clinical significance of asymptomatic endometrial polyps: cross-sectional study. J Minim Invasive Gynecol 2009;16:465–71
   PubMed Web of Science ®Google Scholar
• DeWaay DJ, Syrop CH, Nygaard IE, et al. Natural history of uterine polyps and leiomyomata. Obstet Gynecol 2002;100:3–7
   PubMed Web of Science ®Google Scholar
• Silva Reis PA, Nogueira AA, Reis FJ, et al. Is hysteroscopic appearance a safe means of differentiating malignant from benign endometrial polyps in postmenopausal women? Gynaecol Endosc 2001;10:49–51
   Google Scholar