612
Views
90
CrossRef citations to date
0
Altmetric
Review

Type 2 diabetes mellitus as risk factor for colorectal cancer

&
Pages 84-98 | Received 31 Dec 2007, Accepted 22 Feb 2008, Published online: 10 Oct 2008

References

  • Anderson M L, Pasha T M, Leighton J A. Endoscopic perforation of the colon: Lessons from a 10-year study. Am J Gastroenterol 2000; 95: 3418–3422
  • Bach L A, Rechler M M. Insulin-like growth factors and diabetes. Diabetes Metab Rev 1992; 8: 229–257
  • Bang P, Nygren J, Carlsson-Skwirut C, Thorell A, Ljungqvist O. Postoperative induction of insulin-like growth factor binding protein-3 proteolytic activity: relation to insulin and insulin sensitivity. J Clin Endocrinol Metab 1998; 83: 2509–2515
  • Baserga R. The insulin-like growth factor I receptor: A key to tumour growth. Cancer Res 1995; 55: 249–252
  • Bjork J, Nilsson J, Hultcrantz R, Johansson C. Growth-regulatory effects of sensory neuropeptides epidermal growth factor insulin and somatostatin on the non-transformed intestinal epithelial cell line IEC-6 and the colon cancer cell line HT 29. Scand J Gastroenterol 1993; 28: 879–884
  • Bowker S L, Majumdar S R, Veugelers P, Johnson J A. Increased cancer-related mortality for patients with type 2 diabetes who use sulphonylureas or insulin. Diabetes Care 2006; 29: 254–258
  • Burgering B M, Medema R H, Maassen J A, van de Wetering M L, van der Eb A J, McCormick F, Bos J L. Insulin stimulation of gene expression mediated by p21ras activation. EMBO J 1991; 10: 1103–1109
  • Colangelo L A, Gapstur S M, Gann P H, Dyer A R, Liu K. Colorectal cancer mortality and factors related to the insulin resistance syndrome. Cancer Epidemiol Biomarkers Prev 2002; 11: 385–391
  • Corleta H E, Capp E, Corleta O C. Insulin receptor tyrosine kinase activity in colon carcinoma. Braz J Med Biol Res 1996; 29: 1593–1597
  • Corpet D E, Peiffer G, Tache S. Glycemic index nutrient density and promotion of aberrant crypt foci in rat colon. Nutr Cancer 1998; 32: 29–36
  • Corpet D E, Jacquinet C, Peiffer G, Tache S. Insulin injections promote the growth of aberrant crypt foci in the colon of rats. Nutr Cancer 1997; 27: 316–320
  • Cotton P B, Durkalski V L, Pineau B C, Palesch Y Y, Mauldin P D, Hoffman B, Vining D J, Small W C, Affronti J, Rex D, Kopecky K K, Ackerman S, Burdick J S, Brewington C, Turner M A, Zfass A, Wright A R, Iyer R B, Lynch P, Sivak M V, Butler H. Computed tomographic colonography virtual colonoscopy: A multicenter comparison with standard colonoscopy for detection of colorectal neoplasia. JAMA 2004; 291: 1713–1719
  • Coughlin S S, Calle E E, Teras L R, Petrelli J, Thun M J. Diabetes mellitus as a predictor of cancer mortality in a large cohort of US adults. Am J Epidemiol 2004; 159: 1160–1167
  • Dunn S E, Kari F W, French J, Leininger J R, Travlos G, Wilson R, Barrett J C. Dietary restriction reduces insulin-like growth factor I levels which modulates apoptosis cell proliferation and tumour progression in p53-deficient mice. Cancer Res 1997; 57: 4667–4672
  • Flier J S, Usher P, Moses A C. Monoclonal antibody to the type I insulin-like growth factor IGF-I. receptor blocks IGF-I receptor-mediated DNA synthesis: clarification of the mitogenic mechanisms of IGF-I and insulin in human skin fibroblasts. Proc Natl Acad Sci USA 1986; 83: 664–668
  • Gatto N M, Frucht H, Sundararajan V, Jacobson J S, Grann V R, Neugut A I. Risk of perforation after colonoscopy and sigmoidoscopy: A population-based study. J Natl Cancer Inst 2003; 95: 230–236
  • Geier A, Beery R, Haimshon M, Hemi R, Lunenfeld B. Serum and insulin inhibit cell death induced by cycloheximide in the human breast cancer cell line MCF-7. In Vitro Cell Dev Biol 1992; 28A: 415–418
  • Giovannucci E. Insulin and colon cancer. Cancer Causes Control 1995; 6: 164–179
  • Hardcastle J D, Chamberlain J O, Robinson M H, Moss S M, Amar S S, Balfour T W, James P D, Mangham C M. Randomised controlled trial of faecal-occult-blood screening for colorectal cancer. Lancet 1996; 348: 1472–1477
  • Hawk E T, Levin B. Colorectal cancer prevention. J Clin Oncol 2005; 23: 378–391
  • Hu F B, Manson J E, Liu S, Hunter D, Colditz G A, Michels K B, Speizer F E, Giovannucci E. Prospective study of adult onset diabetes mellitus type 2 and risk of colorectal cancer in women. J Natl Cancer Inst 1999; 91: 542–547
  • Jhun B H, Meinkoth J L, Leitner J W, Draznin B, Olefsky J M. Insulin and insulin-like growth factor-I signal transduction requires p21ras. J Biol Chem 1994; 269: 5699–5704
  • Katz L EL, Cohen P, Rosenfeld R. Clinical significance of IGF binding proteins. Endocrinologist 1995; 5: 36–43
  • Khaw K T, Wareham N, Bingham S, Luben R, Welch A, Day N. Preliminary communication: Glycated hemoglobin diabetes and incident colorectal cancer in men and women. A prospective analysis from the European prospective investigation into cancer – Norfolk study. Cancer Epidemiol Biomarkers Prev 2004; 13: 915–919
  • Kolligs F T, Stieber P, Nagel D, Schäfer C, Becker C, Geisbüsch S, Lottes A., Reiser M F, Göke B, Graser A. A prospective comparison of colonoscopy sigmoidoscopy CT colonography and stool tests in an average risk population. ASCO Gastrointestinal Cancers Symposium Proceedings 2008 2008; #282: 209
  • Koohestani N, Tran T T, Lee W, Wolever T M, Bruce W R. Insulin resistance and promotion of aberrant crypt foci in the colons of rats on a high-fat diet. Nutr Cancer 1997; 29: 69–76
  • Koohestani N, Chia M C, Pham N A, Tran T T, Minkin S, Wolever T M, Bruce W R. Aberrant crypt focus promotion and glucose intolerance: Correlation in the rat across diets differing in fat n-3 fatty acids and energy. Carcinogenesis 1998; 19: 1679–1684
  • Kronborg O, Fenger C, Olsen J, Jorgensen O D, Sondergaard O. Randomised study of screening for colorectal cancer with faecal-occult-blood test. Lancet 1996; 348: 1467–1471
  • Kune G A, Kune S, Watson L F. Colorectal cancer risk chronic illnesses operations and medications: Case control results from the Melbourne Colorectal Cancer Study. Cancer Res 1988; 48: 4399–4404
  • Larsson S C, Orsini N, Wolk A. Diabetes mellitus and risk of colorectal cancer: a meta-analysis. J Natl Cancer Inst 2005; 97: 1679–1687
  • La Vecchia C, Negri E, Decarli A, Franceschi S. Diabetes mellitus and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev 1997; 6: 1007–1010
  • Lee W M, Lu S, Medline A, Archer M C. Susceptibility of lean and obese Zucker rats to tumourigenesis induced by N-methyl-N-nitrosourea. Cancer Lett 2001; 162: 155–160
  • Le Marchand L, Wilkens L R, Kolonel L N, Hankin J H, Lyu L C. Associations of sedentary lifestyle obesity smoking alcohol use and diabetes with the risk of colorectal cancer. Cancer Res 1997; 57: 4787–4794
  • Levin T R, Conell C, Shapiro J A, Chazan S G, Nadel M R, Selby J V. Complications of screening flexible sigmoidoscopy. Gastroenterology 2002; 123: 1786–1792
  • Lieberman D A, Weiss D G, Bond J H, Ahnen D J, Garewal H, Chejfec G. Use of colonoscopy to screen asymptomatic adults for colorectal cancer. Veterans Affairs Cooperative Study Group 380. N Engl J Med 2000; 343: 162–168
  • Limburg P J, Anderson K E, Johnson T W, Jacobs Jr D R, Lazovich D, Hong C P, Nicodemus K K, Folsom A R. Diabetes mellitus and subsite-specific colorectal cancer risks in the Iowa Women's Health Study. Cancer Epidemiol Biomarkers Prev 2005; 14: 133–137
  • Luning T H, Keemers-Gels M E, Barendregt W B, Tan A C, Rosman C. Colonoscopic perforations: A review of 30 366 patients. Surg Endosc 2007; 21: 994–997
  • Ma J, Giovannucci E, Pollak M, Leavitt A, Tao Y, Gaziano J M, Stampfer M J. A prospective study of plasma C-peptide and colorectal cancer risk in men. J Natl Cancer Inst 2004; 96: 546–553
  • Macaulay V M. Insulin-like growth factors and cancer. Br J Cancer 1992; 65: 311–320
  • Mandel J S, Bond J H, Church T R, Snover D C, Bradley G M, Schuman L M, Ederer F. Reducing mortality from colorectal cancer by screening for faecal occult blood. Minnesota Colon Cancer Control Study. N Engl J Med 1993; 328: 1365–1371
  • McKeown-Eyssen G. Epidemiology of colorectal cancer revisited: Are serum triglycerides and/or plasma glucose associated with risk? Cancer Epidemiol. Biomarkers Prev 1994; 3: 687–695
  • Meyerhardt J A, Catalano P J, Haller D G, Mayer R J, Macdonald J S, Benson A B, III, Fuchs C S. Impact of diabetes mellitus on outcomes in patients with colon cancer. J Clin Oncol 2003; 21: 433–440
  • Moller D E, Flier J S. Insulin resistance – mechanisms syndromes and implications. N Engl J Med 1991; 325: 938–948
  • Morikawa T, Kato J, Yamaji Y, Wada R, Mitsushima T, Shiratori Y. A comparison of the immunochemical faecal occult blood test and total colonoscopy in the asymptomatic population. Gastroenterology 2005; 129: 422–428
  • Nilsen T I, Vatten L J. Prospective study of colorectal cancer risk and physical activity diabetes blood glucose and BMI: exploring the hyperinsulinaemia hypothesis. Br J Cancer 2001; 84: 417–422
  • O'Mara B A, Byers T, Schoenfeld E. Diabetes mellitus and cancer risk: A multisite case-control study. J Chronic Dis 1985; 38: 435–441
  • Pickhardt P J, Choi J R, Hwang I, Butler J A, Puckett M L, Hildebrandt H A, Wong R K, Nugent P A, Mysliwiec P A, Schindler W R. Computed tomographic virtual colonoscopy to screen for colorectal neoplasia in asymptomatic adults. N Engl J Med 2003; 349: 2191–2200
  • Powell D R, Suwanichkul A, Cubbage M L, DePaolis L A, Snuggs M B, Lee P D. Insulin inhibits transcription of the human gene for insulin-like growth factor-binding protein-1. J Biol Chem 1991; 266: 18868–18876
  • Ragozzino M, Melton L J, III, Chu C P, Palumbo P J. Subsequent cancer risk in the incidence cohort of Rochester Minnesota residents with diabetes mellitus. J Chronic Dis 1982; 35: 13–19
  • Renehan A G, Zwahlen M, Minder C, O'Dwyer S T, Shalet S M, Egger M. Insulin-like growth factor IGF-I IGF binding protein-3 and cancer risk: Systematic review and meta-regression analysis. Lancet 2004; 363: 1346–1353
  • Rockey D C, Paulson E, Niedzwiecki D, Davis W, Bosworth H B, Sanders L, Yee J, Henderson J, Hatten P, Burdick S, Sanyal A, Rubin D T, Sterling M, Akerkar G, Bhutani M S, Binmoeller K, Garvie J, Bini E J, McQuaid K, Foster W L, Thompson W M, Dachman A, Halvorsen R. Analysis of air contrast barium enema computed tomographic colonography and colonoscopy: prospective comparison. Lancet 2005; 365: 305–311
  • Sandhu M S, Luben R, Khaw K T. Self reported non-insulin dependent diabetes family history and risk of prevalent colorectal cancer: population based cross sectional study. J Epidemiol Community Health 2001; 55: 804–805
  • Schoen R E, Weissfeld J L, Kuller L H, Thaete F L, Evans R W, Hayes R B, Rosen C J. Insulin-like growth factor-I and insulin are associated with the presence and advancement of adenomatous polyps. Gastroenterology 2005; 129: 464–475
  • Selby J V, Friedman G D, Quesenberry C P, Jr, Weiss N S. A case-control study of screening sigmoidoscopy and mortality from colorectal cancer. N Engl J Med 1992; 326: 653–657
  • Smith R A, Cokkinides V, Eyre H J. American Cancer Society Guidelines for the Early Detection of Cancer 2005. CA Cancer J Clin 2005; 55: 31–44
  • Soos M A, Whittaker J, Lammers R, Ullrich A, Siddle K. Receptors for insulin and insulin-like growth factor-I can form hybrid dimers. Characterisation of hybrid receptors in transfected cells. Biochem J 1990; 270: 383–390
  • Strasser-Vogel B, Blum W F, Past R, Kessler U, Hoeflich A, Meiler B, Kiess W. Insulin-like growth factor IGF-I and -II and IGF-binding proteins-1, -2 and -3 in children and adolescents with diabetes mellitus: Correlation with metabolic control and height attainment. J Clin Endocrinol. Metab 1995; 80: 1207–1213
  • Tran T T, Medline A, Bruce W R. Insulin promotion of colon tumours in rats. Cancer Epidemiol Biomarkers Prev 1996; 5: 1013–1015
  • Tran T T, Gupta N, Goh T, Naigamwalla D, Chia M C, Koohestani N, Mehrotra S, McKeown-Eyssen G, Giacca A, Bruce W R. Direct measure of insulin sensitivity with the hyperinsulinemic-euglycemic clamp and surrogate measures of insulin sensitivity with the oral glucose tolerance test: Correlations with aberrant crypt foci promotion in rats. Cancer Epidemiol Biomarkers Prev 2003; 12: 47–56
  • Underwood L E, Thissen J P, Lemozy S, Ketelslegers J M, Clemmons D R. Hormonal and nutritional regulation of IGF-I and its binding proteins. Horm Res 1994; 42: 145–151
  • Valverde A M, Fabregat I, Burks D J, White M F, Benito M. IRS-2 mediates the antiapoptotic effect of insulin in neonatal hepatocytes. Hepatology 2004; 40: 1285–1294
  • Vogelstein B, Fearon E R, Hamilton S R, Kern S E, Preisinger A C, Leppert M, Nakamura Y, White R, Smits A M, Bos J L. Genetic alterations during colorectal-tumour development. N Engl J Med 1988; 319: 525–532
  • Watkins L F, Lewis L R, Levine A E. Characterization of the synergistic effect of insulin and transferrin and the regulation of their receptors on a human colon carcinoma cell line. Int J Cancer 1990; 45: 372–375
  • Will J C, Galuska D A, Vinicor F, Calle E E. Colorectal cancer: another complication of diabetes mellitus. Am J Epidemiol 1998; 147: 816–825
  • Winawer S J, Zauber A G, Ho M N, O'Brien M J, Gottlieb L S, Sternberg S S, Waye J D, Schapiro M, Bond J H, Panish J F. Prevention of colorectal cancer by colonoscopic polypectomy. The National Polyp Study Workgroup. N Engl J Med 1993; 329: 1977–1981
  • Wu Y, Yakar S, Zhao L, Hennighausen L, LeRoith D. Circulating insulin-like growth factor-I levels regulate colon cancer growth and metastasis. Cancer Res 2002; 62: 1030–1035
  • Yang Y X, Hennessy S, Lewis J D. Insulin therapy and colorectal cancer risk among type 2 diabetes mellitus patients. Gastroenterology 2004; 127: 1044–1050
  • Yang Y X, Hennessy S, Lewis J D. Type 2 diabetes mellitus and the risk of colorectal cancer. Clin Gastroenterol Hepatol 2005; 3: 587–594

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.