Pharmacological Survey of Medicinal Plants for Activity at Ligand-Gated Ion Channels: Selective Interaction with 5-HT3 Receptors

References

• Abdel-Malek S, Bastien JW, Mahler WF, Jia Q, Reinecke MG, Robinson Jr. WE, ShuYH, Zalles-Asin J (1996): Drug leads from the Kallawaya herbalists of Bolivia. 1. Background, rationale, protocol and anti-HIV activity J Ethnopharma-col 50: 157–166.
   Google Scholar
• Bandoni AL, Mendiondo ME, Rondina RVD, Coussio JD (1972): Survey of Argentine medicinal plants. I. Folklore and phytochemical screening. Lloydia 35: 69–80.
   Google Scholar
• Bastien JAV (1983): Pharmacopeia of Qollahuaya Andeans. J Ethnopharmacol 8: 97–111.
   PubMed Web of Science ®Google Scholar
• Bhakuni DS, Bittner M, Marticorena C, Silva M, Weldt E, Hoeneisen M, Hartwell JL (1976): Screening of Chilean plants for anticancer activity I. Lloydia 39: 225–243.
   PubMed Web of Science ®Google Scholar
• Boess FG, Beroukhim R, Martin IL (1995): Ultrastructure of the 5-hydroxytryptamine3 receptor. J Neurochem 64: 1401–1405.
   Google Scholar
• Butler A, Elswood CJ, Burridge J, Ireland SJ, Bunce KT, Kilpatrick GJ, Tyers MB (1990): The pharmacological characterization of 5-HT3 receptors in three isolated preparations derived from guinea-pig tissues. Br J Phar-macol 101: 591–598.
   PubMed Web of Science ®Google Scholar
• Cardellina JH, II, Munro MH, Fuller RW, Nanfredi KP, McKee TC, Tischler M, Bokesch HR, Gustafson KR, Beutler JA, Boyd MR (1993): A chemical screening strategy for the dereplication and prioritization of HIV-inhibitory aqueous natural product extracts. J Nat Prod 56: 1123–1129.
   PubMedGoogle Scholar
• Chen C, Okayama H (1987): High efficiency transformation of mammalian cells by plasmid DNA. Mol Cell Biol 7: 2745–2750.
   PubMed Web of Science ®Google Scholar
• Chen Q, Moulder K, Tenkova T, Hardy K, Olney JW, Romano C (1999): Excitotoxic cell death dependent on inhibitory receptor activation. Exper Neurol 160: 215–220.
   PubMedGoogle Scholar
• Ciccia G, Coussio J, Mongelli E (2000): Insecticidal activity against Aedes aegypti larvae of some medicinal South American plants. J Ethnopharmacol 72: 185–189.
   PubMed Web of Science ®Google Scholar
• Criswell HE, Simson PE, Duncan GE, McCown TJ, Herbert JS, Morrow AL, Breese GR (1993): Molecular basis of regionally specific action of ethanol on y-aminobutyric acidA receptors: Generalization to other ligand-gated ion channels. J Pharmacol Exper Ther 267: 522–537.
   PubMedGoogle Scholar
• Darias V, Bravo L, Rabanal R, Sanchez-Mateo C, Gonzalez-Luis RNI, Hernandez-Perez AM (1989): New contribution to the ethnopharmacological study of the Canary Islands. J Ethnopharmacol 25: 77–92.
   PubMed Web of Science ®Google Scholar
• Das P, Bell-Horner CL, Machu TK, Dillon GH (2003) The GABAA receptor antagonist picrotoxin inhibits 5-hydroxytryptamine type 3A receptors. Neuropharmacol 44: 431–438.
   PubMedGoogle Scholar
• De Lucca M, Zalles-Asin J (1992): Flora Medicinal Boliviana, Los Amigos del Libro, La Paz-Cochabamba, p. 498.
   Google Scholar
• De Ponti F, Tonini M (2001): Irritable bowel syndrome: new agents targeting serotonin receptor subtypes. Drugs 61: 317–332.
   PubMed Web of Science ®Google Scholar
• Dibas MI, Gonzales EB, Das P, Bell-Horner CL, Dillon GH (2002): Identification of a novel residue within the second transmembrane domain that confers use-facilitated block by picotoxin in glycine al receptors. J Biol Chem 277: 9112–9117.
   PubMedGoogle Scholar
• Dubin AE, Huvar R, D 'Andrea MR, Pyati J, Zhu JY, Joy KC, Wilson SJ, Galindo JE, Glass CA, Luo L, Jackson MR, Lovenberg TW, Erlander MG (1999): The pharmacological and functional characteristics of the serotonin 5-HT(3A) receptor are specifically modified by a 5-HT(3B) receptor subunit. J Biol Chem 274: 30799–30810.
   PubMed Web of Science ®Google Scholar
• Filipoy A (1994): Medicinal plants of the Pilaga of central Chaco. J Ethnopharmacol 44: 181–193.
   PubMedGoogle Scholar
• Giberti GC (1983): Herbal folk medicine in northwestern Argentina: Compositae. J Ethnopharmacol 7: 321–341.
   PubMed Web of Science ®Google Scholar
• Gehlert DR, Schober DA, Gackenheimer SL, Mais DE, Ladouceur G, Robertson DW (1993): Synthesis and evaluation of [125I]-(S)-iodozacopride, a high affinity radioligand for 5HT3 receptors. Neurochem Int 23: 373–383.
   PubMedGoogle Scholar
• Girault L (1987): Kallawaya Curanderos Itinerantes De Los Andes, Paz UNICEF, ORSTOM, La Bolivia, p. 486.
   Google Scholar
• Hamilton BJ, Lennon DJ, Im, HK, Im WB, Seeburg PH, Carter DB (1993): Stable expression of cloned rat GABAA recep-tor subunits in a human kidney cell line. Neurosci Lett 153: 206–209.
   PubMed Web of Science ®Google Scholar
• Harborne JB (1984): Phytochemical Methods, A Guide to Modern Techniques for Plant Analysis. London, UK Chapman & Hall.
   Google Scholar
• Hesketh PJ (2000): Comparative review of 5-HT3 receptor antagonists in the treatment of acute chemotherapy-induced nausea and vomiting. Cancer Invest 18: 163–173.
   PubMed Web of Science ®Google Scholar
• Hevers W, Luddens H (1998): The diversity of GABAA recep-tors: pharmacological and electrophysiological properties of GABAA channel subtypes. Mol Neurobiol 18: 35–86.
   PubMedGoogle Scholar
• Hong Q (1992): Phytochemical studies of medicinal plants as potential anti-mycobacterial drugs. Masters Thesis at Texas Christian University, Fort Worth Texas.
   Google Scholar
• Hoyer D, Clarke DE, Fozard JR, Hartig PR, Martin GR, Mylecharane EJ, Saxena PR, Humphrey PP (1994): Inter-national Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin). Pharmacol Rev 46: 157–203.
   PubMed Web of Science ®Google Scholar
• Hoyer D, Martin G (1997): 5-HT receptor classification and nomenclature: towards a harmonization with the human genome. Neuropharmacol 36: 419–428.
   PubMed Web of Science ®Google Scholar
• Kankaanpaa A, Meririnne E, Seppala T (2002): 5-HT3 receptor antagonist MDL 72222 attenuates cocaine- and mazindol, butnot methylphenidate -induced neurochemical andbehavioral effects in the rat. Psychopharmacology 159: 341–350.
   PubMedGoogle Scholar
• Karlin A (2002) Emerging structure of the nicotinic acetyl-choline receptors. Nature Rev Neurosci 3: 102–114.
   PubMed Web of Science ®Google Scholar
• King GR, Xiong Z, Douglas S, Ellinwood EH (2000): Long-term blockade of cocaine sensitization by ondansetron, a 5-HT3 receptor antagonist. Eur J Pharmacol 394: 97–101.
   PubMed Web of Science ®Google Scholar
• Kugelman M, Liu WC, Axelrod M, McBride TJ, Rao KV (1976): Indicine-N-oxide: the antitumor principle of Heliotropium indicum. Lloydia 39: 125–128.
   PubMedGoogle Scholar
• Liddell JR, Logie CG (1993): A re-investigation of the alkaloids of Senecio pterophorus. Phytochemistry 34: 1629–1631.
   Google Scholar
• Luedtke RR, Freeman RA, Martin MW, Bastien JW, Zalles-Asin J, Reinecke MG (2002): Pharmacological survey of medi-cinal plants for activity at dopamine receptor subtypes. I. Activation of Dl -like receptor linked adenylyl cyclase. Pharm Biol 40: 315–325.
   Google Scholar
• Luedtke RR, Freeman RA, Volk M, Arfan M, Reinecke MG (2003): Pharmacological survey of medicinal plants for activity at dopamine receptor subtypes. II. Screen for activ-ity at the D1 and D2 dopamine receptor subtypes. Pharm Biol 41: 45–58.
   Google Scholar
• Luedtke RR, Mach RH (2003): Progress in developing D3 dopamine receptor ligands as potential therapeutic agents for neurological and neuropsychiatric disorders. Current Pharmaceutical Design 9: 643–671.
   PubMedGoogle Scholar
• Marczynski TJ (1998): GABAergic deafferentation hypothesis of brain aging and Alzheimer's disease revisited. Brain Res Bulletin 45: 341–379.
   PubMed Web of Science ®Google Scholar
• Miyazawa A, Fujiyoshi Y, Unwin N (2003): Structure and gating mechanism of the acetylcholine receptor pore. Nature 424: 949–955.
   Google Scholar
• Morales M, Wang SD (2002): Differential composition of 5-hydroxytryptamine receptors synthesized in the rat CNS and peripheral nervous system. J Neurosci 22: 6732–6741.
   PubMed Web of Science ®Google Scholar
• Nayeem N, Green TP, Martin IL, Barnard EA (1994): Quater-nary structure of the native GABAA receptor determined by electron microscopic image analysis. J Neurochem 62: 815–818.
   PubMed Web of Science ®Google Scholar
• Olano I, Alonso E, Cerdeiras MP, Fernandez J, Ferreira F, Moyna P, Soubes M, Vazquez A, Vero S, Bassagoda MJ (1996): Screening of Uruguayan medicinal plants for antimicrobial activity Part II. J Ethnopharmacol 53: 111–115.
   Google Scholar
• Panicker S, Cruz H, Arrabit C, Slesinger PA (2002): Evidence for a centrally located gate in the pore of a serotonin-gated ion channel. J Neurosci 22: 1629–1639.
   Google Scholar
• Perez C, Anesini C (1994): Inhibition of Pseudomonas aerugi-nosa by Argentinean medicinal plants. Fitoterapia 65: 169–172.
   Google Scholar
• Porras G, De Deurwaerdere P, Moison D, Spampinato U (2003): Conditional involvement of striatal serotonin3 receptors in the control of in vivo dopamine outflow in the rat striatum. Eur J Neurosci 17: 771–781.
   PubMedGoogle Scholar
• Reeves DC, Lummis SC (2002): The molecular basis of the structure and function of the 5-HT3 receptor: a model ligand-gated ion channel (review). Mol Membr Biol 19: 11–26.
   PubMed Web of Science ®Google Scholar
• Reinecke MG, Hong Q, Franzblau SG (2000): Phytochemical studies of medicinal plants as sources of leads for potential anti-tuberculosis drugs. Abst Int Cong Nat Prod Res 41: P–170.
   Google Scholar
• Rios JL, Recio MC, Villar A (1987): Antimicrobial activity of selected plants employed in the Spanish Mediterranean area. J Ethnopharmacol 21: 139–152.
   PubMed Web of Science ®Google Scholar
• Steward LI, Boess FG, Steele JA, Liu D, Wong N, Martin IL (2000): Importance of phenylalanine 107 in agonist recog-nition by the 5-hydroxytryptamine (3A) receptor. Mol Pharmacol 57: 1249–1255.
   Google Scholar
• Stewart A, Davies PA, Kirkness EF, Safa P, Hales TG (2003): Introduction of the 5-HT3B subunit alters the functional properties of 5-HT3 receptors native to neuroblastoma cells. Neuropharmacology 44: 214–223.
   PubMedGoogle Scholar
• Sun H, Machu TK (2002): Bicuculline antagonizes 5-HT(3A) and alpha2 glycine receptors expressed in Xenopus oocytes. Eur J Pharmcol 391: 243–249.
   Google Scholar
• Warren FL (1970): In: Manshe RHF, ed., The Alkaloids. Vol. 12, New York, Academic Press, chapter 14.
   Google Scholar
• Yan D, Schulte MK, Bloom KE, White MiM (1999): Structural features of the ligand-binding domain of the serotonin 5HT3 receptor. J Biol Chem 274: 5537–5541.
   Google Scholar
• Yan Z (2002): Regulation of GABAergic inhibition by serotonin signaling in prefrontal cortex: molecular mechanisms and functional implications. Mol Neurobiol 26: 203–216.
   PubMed Web of Science ®Google Scholar