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Pharmaceutical Biology Volume 42, 2004 - Issue 6
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Research Article

Effect of Natural 2,5-Diaryl-3,4-dimethyltetrahydrofuran Lignans on Complement Activation, Lymphocyte Proliferation, and Growth of Tumor Cell Lines

M.S.J. Nascimento Centro de Estudos de Química Orgânica Fitoquímica e Farmacologia da Universidade do Porto, Faculdade de Farmácia Porto Portugal
,
M. Pedro Centro de Estudos de Química Orgânica Fitoquímica e Farmacologia da Universidade do Porto, Faculdade de Farmácia Porto Portugal
,
F. Cerqueira Laboratório de Microbiologia, Faculdade de Farmácia Universidade do Porto Porto Portugal
,
M. Bastos Departamento de Engenharia Química, Faculdade de Engenharia Universidade do Porto Porto Portugal
,
L.M. Vieira Instituto de Ciências Biomédicas de Abel Salazar Universidade do Porto Porto Portugal
,
A. Kijjoa Centro Interdisciplinar de Investicão Marinhae Ambiental Universidad do Porto Porto Portugal
&
M.M.M. Pinto Centro de Estudos de Química Orgânica Fitoquímica e Farmacologia da Universidade do Porto, Faculdade de Farmácia Porto Portugal
 show all
Pages 449-453 | Published online: 29 Sep 2008

References

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  • Biftu T, Stevensen R (1987): Natural 2,5-bisaryltetrahydrofuran lignans: Platelet-activating factor antagonists. Phytother Res 1: 97–106.
  • Cho JY, Kim AR, Yoo ES, Baik KU, Park MH (1999): Immunomodulatory effect of arctigenin, a lignan com-pound, on tumour necrosis factor-alpha and nitric oxide production, and lymphocyte proliferation. J Pharm Phar-macol 51: 1267–1273.
  • Cho JY, Park J, Kim AR, Yoo ES, Baik KU, Park MH (2001): Savinin, a lignan from Pterocarpus santalinus inhibits tumor necrosis factor-alpha production and T cell prolifer-ation. Biol Pharm Bull 24: 167–171.
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  • Mosmarm T (1983): Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Meth 65: 55–63.
  • Shimomura H, Sashida Y, Oohara M (1988): Lignans from Machilus thunbergii. Phytochemistry 27: 634–636.
  • Skehan P, Storeng R, Scudiero D, Monks A, McMahon J, Vistica D, Warren if, Bokesch H, Kenney S, Boyd MR (1990): New colorimetric cytotoxicity assay for anticancer-drug screening. J Natl Cancer Inst 82: 1107–1112.
  • Su B, Zhu Q, Gao K, Yuan C, Jia Z (1999): Lignan and phenyl-propanoid glycosides from Lancea tibetica and their anti-tumor activity. Planta Med 65: 558–561.
  • Vieira LM, Kijjoa A, Silva ANIS, Mondranondra I-0, Herz W (1998): 2,5-Dyary1-3,4-dimethyltetrahydrofuran lignans from Talauma hodgsonii. Phytochemistry 48: 1079–1081.
  • Ward RS (1997): Lignans, neolignans and related compounds. Nat Prod Rep 14: 43–74.

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