Antinociceptive Activities of Aqueous and Ethanol Extracts of Piper betle. Leaves in Rats

References

• Anonymous (1992): The Wealth of India. The Dictionary of Indian Raw Materials and Industrial Products. Raw Material Vol. 5, Publication and Information directorate, CSIR, pp. 84–94.
   Google Scholar
• Arambewela LSR, Arawwawala LDAM, Ratnasooriya WD (2004): Antinociceptive activities of aqueous and etahnolic extracts of Alpinia calcarata. rhizomes in rats. J Ethnopharmacol 95: 311–316. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Arambewela LSR, Arawwawala LDAM, Ratnasooriya WD (2003): Safety evaluation of Sri Lankan Piper betle. leaf extracts in rats. J Trop Med Plants 4: 195–198. [CSA]
   Google Scholar
• Badio B, Shi D, Garraffo HM, Daily JN (1995): Antinociceptive effects of the alkaloid epibatidine: Further studies on involvement of nicotine receptors. Drug Develop Res 36: 46–59. [CSA], [CROSSREF]
   Web of Science ®Google Scholar
• Choudhary D, Kale RK (2002): Antioxidant and nontoxic properties of Piper betle. leaf extract: in vitro. and in vivo. studies. Phytother Res 61: 461–466. [CSA], [CROSSREF]
   Google Scholar
• Dassanayake MD, Fosberg FR (1987): A Revised Hand Book to the Flora of Ceylon. New Delhi, Amreind, pp. 287–288.
   Google Scholar
• Dubuission D, Dennis SG (1977): The formalin test: A quantitative study of the analgesia effects of morphine, meperidine and brain stem stimulation in rats and cats. Pain 4: 167–174. [CSA]
   Web of Science ®Google Scholar
• Farnsworth NR (1996): Biological and phytochemical screening of plants. J Pharm Sci 55: 225–276. [CSA]
   Google Scholar
• File SE, Wardill A (1975): Validity of head dipping as a measure of exploration in modified hole-board. Psychopharmacol 44: 53–57. [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Jayaweera DMA (1982): Medicinal Plants Used in Ceylon, Vol. 5. Colombo, National Science Council of Sri Lanka, p. 201.
   Google Scholar
• Jensen TS, Yaksh TL (1986): Effects of an intrathecal dopamine agonists, apomorphine, on thermal and chemical evoked noxious responses in rats. Brain Res 296: 285–293. [CSA], [CROSSREF]
   Web of Science ®Google Scholar
• Langerman L, Zakouski ML, Piskoun B, Grant GJ (1995): Hot plate versus tail flick: Evaluation of acute tolerance to continuous morphine infusion in the rat model. J Pharmacol Toxicol Methods 34: 23–28. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Li BY, Nalwalk JW, Barker LA, Cumming P, Parsons MF, Hougn LB (1996): Characterization of the antinociceptive properties of cimetidine and a structural analog. J Pharmacol Exp Ther 276: 500–508. [PUBMED], [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Lopez–Munoz FJ, Salazar LA, Castaneda–Hernandes G, Villarreal JE (1993): A new model to assess analgesic activity: Pain induced functional impairement in the rat (PIFIR). Drug Develop Res 28: 169–175. [CSA], [CROSSREF]
   Web of Science ®Google Scholar
• Majumdar B, Chaudhuri SGR, Ray A, Bandyopadhyay SK (2003): Effect of ethanol extract of Piper betle. Linn leaf on healing of NSAID-induced experimental ulcer—A novel role of free radical scavenging action. Indian J Exp Biol 41: 311–315. [PUBMED], [INFOTRIEVE], [CSA]
   PubMedGoogle Scholar
• Martindale J, Bland–Ward PA, Chessell IP (2001): Inhibition of C-fibre mediated sensory transmission in the rat following intraplantar formalin. Neurosci Lett 316: 33–36. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Murray CW, Porreca F, Cowan A (1988): Methodological refinements in the mouse paw formalin test an animal model of tonic pain. J Pharmacol Methods 20: 175–186. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Ossipov MH, Harris S, Lloyd P, Messineo E, Lin BS, Bagley J (1990): Antinociceptive interaction between opioids and medetomidine: Systemic additivity and spinal synergy. Anesthesiology 73: 1227–1235. [PUBMED], [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Plaznic A, Stefanski R, Palejko W, Kotawski W (1993): The role of accumbense GABA-B receptors in the regulation of rat behavior. Neurosci Res Common 12: 23–30. [CSA]
   Google Scholar
• Rang HP, Dale MM, Ritter JM (1995): Pharmacology. London, Churchill Livingstone.
   Google Scholar
• Ratnasooriya WD, Premakumara GAS (1996): Piper betle. leaves impairs masculine sexual behavior of rats. Med Sci Res 24: 303–306. [CSA]
   Google Scholar
• Ratnasooriya WD, Premakumara GAS (1997): Piper betle. leaves reversibly inhibits fertility of male rats. Vidyodaya J Sci 7: 15–21. [CSA]
   Google Scholar
• Ratnasooriya WD, Jayawardena KGI, Premakumara GAS (1990): Antimotility effects of Piper betle. (L) leaf extract on washed human spermatozoa. J Natl Sci Coun Sri Lanka 18: 53–60. [CSA]
   Google Scholar
• Santhanam G, Nagarajan S (1990): Wound healing activity of Curcuma aromatica. and Piper betle.. Fitoterapia 61: 458–459. [CSA]
   Google Scholar
• Saravanan R, Prakasam A, Ramesh B, Pugalendi KV (2002): Influence of Piper betle. on hepatic marker enzymes and tissue antioxidant status in ethanol-treated wistar rats. J Med Food 5: 197–204. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Santhakumari P, Prakasam A, Pugalendi KV (2003): Modulation of oxidative stress parameters by treatment with Piper betle. leaf in streptozotocin induced diabetic rats. Indian J Pharmacol 35: 373–378. [CSA]
   Google Scholar
• Scuka M, Mazrzymas JW (1991): Post synaptic potentiation and desensitization at the vertebrate end-plate receptors. Prog Neurobio 38: 19–33. [CSA], [CROSSREF]
   Web of Science ®Google Scholar
• Stewart J, Badiani A (1993): Tolerance and sensitization to the behavioural effects of drugs. Behavi Pharmacol 4: 289–312. [CSA]
   PubMed Web of Science ®Google Scholar
• Tewari SN, Nayak M (1991): Activity of four plant leaf extracts against three fungal pathogens of rice. Trop Agric 68: 373–375. [CSA]
   Web of Science ®Google Scholar
• Tjolsen A, Berge DG, Hunskaar S, Rosland JH, Hole K (1992): The formalin test: An evaluation of the method. Pain 51: 5–17. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Vedhanayaki G, Shastri GV, Kuruvilla A (2003): Analgesic activity of Piper longum. Linn. root. Indian J Exp Biol 41: 649–651. [PUBMED], [INFOTRIEVE], [CSA]
   PubMedGoogle Scholar
• Wong CH, Day P, Yarmush J, Wu W, Zbuzek UK (1994): Nifedipine-induced analgesia after epidural injections in rats. Anesthes Analges 79: 303–306. [CSA]
   PubMed Web of Science ®Google Scholar