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Research Article

Study of Furostenol Glycoside Fraction of Tribulus terresteris. on Male Sexual Function in Rats

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Pages 191-198 | Accepted 03 Aug 2007, Published online: 07 Oct 2008

References

  • Adaikan P G, Gauthaman K, Prasad R N, Ng S C. Proerectile pharmacological effects of Tribulus terrestris. extract on the rabbit corpus cavernosum. Ann Acad Med Singapore 2000; 29: 22–26
  • Adimoelja A. Phytochemicals and the breakthrough of traditional herbs in the management of sexual dysfunctions. Int J Androl 2000; 23: 82–84, (Suppl 2)
  • Adimoelja A, Adaikan P G. Protodioscin from herbal plant Tribulus terrestris. L. improves male sexual functions possibly via DHEA. Int J Impot Res 1997; 9: S64
  • Ageel A M, Islam M W, Ginawi O T, Al-Yahya M A. Evaluation of the aphrodisiac activity of Litsea chinesis. (Lauraceae) and Orchis maculate. (Orchidaceae) extracts in rats. Phytotherapy 1994; 8: 103–105
  • Aung H H, Dey L, Rand V, Yuan C S. Alternative therapies for male and female sexual dysfunction. Am J Chin Med 2004; 32: 161–173
  • Aversa A, Isidori A M, De Martino M U, Caprio M, Fabbrini E, Rocchietti-March M, Frajese G, Fabbri A. Androgens and penile erection: Evidence for a direct relationship between free testosterone and cavernous vasodilation in men with erectile dysfunction. Clin Endocrinol (Oxf) 2000; 53: 517–522
  • Behr-Roussel D, Gorny D, Mevel K, Caisey S, Bernabe J, Burgess G, Wayman C, Alexandre L, Giuliano F. Chronic sildenafil improves erectile function and endothelium-dependent cavernosal relaxations in rats: Lack of tachyphylaxis. Eur Urol 2005a; 47: 87–91
  • Behr-Roussel D, Gorny D, Mevel K, Compagnie S, Kern P, Sivan V, Bernabe J, Bedigian M P, Alexandre L, Giuliano F. Erectile dysfunction: An early marker for hypertension? A longitudinal study in spontaneously hypertensive rats. Am J Physiol Regul Integr Comp Physiol 2005b; 288: R276–283
  • Chamness S L, Ricker D D, Crone J K, Dembeck C L, Maguire M P, Burnett A L, Chang T S. The effect of androgen on nitric oxide synthase in the male reproductive tract of the rat. Fertil Steril 1995; 63: 1101–1107
  • Dinsmore W, Evans C. ABC of sexual health: Erectile dysfunction. BMJ 1999; 318: 387–390
  • Gauthaman K, Adaikan P G. Effect of Tribulus terrestris. on nicotinamide adenine dinucleotide phosphate-diaphorase activity and androgen receptors in rat brain. J Ethnopharmacol 2005; 96: 127–132
  • Gauthaman K, Adaikan P G, Prasad R N. Aphrodisiac properties of Tribulus terrestris. extract (protodioscin) in normal and castrated rats. Life Sci 2002; 71: 1385–1396
  • Gauthaman K, Ganesan A P, Prasad R N. Sexual effects of puncturevine (Tribulus terrestris.) extract (protodioscin): An evaluation using a rat model. J Altern Complement Med 2003; 9: 257–265
  • Gemalmaz H, Waldeck K, Chapman T N, Tuttle J B, Steers W D, Andersson K E. In vivo in vitro. investigation of the effects of sildenafil on rat cavernous smooth muscle. J Urol 2001; 165: 1010–1014
  • Giuliani D, Ottani A, Ferrari F. Influence of sildenafil on copulatory behavior in sluggish or normal ejaculator male rats: A central dopamine mediated effect?. Neuropharmacology 2002; 42: 562–567
  • Giuliano F, Bernabe J, Alexandre L, Niewoehner U, Haning H, Bischoff E. Pro-erectile effect of vardenafil: In vitro. experiments in rabbits and in vivo. comparison with sildenafil in rats. Eur Urol 2003; 44: 731–736
  • Gould D C, Petty R. The male menopause: Does it exist?. West J Med 2000; 173: 76–78
  • Hadidi K A, Aburjai T, Battah A K. A comparative study of Ferula hermonis. root extracts and sildenafil on copulatory behavior of male rats. Fitoterapia 2003; 74: 242–246
  • Hart B L, Wallach S J, Melese-d'Hospital P Y. Differences in responsiveness to testosterone of penile reflexes and copulatory behavior of male rats. Horm Behav 1983; 17: 274–283
  • Heaton J P, Varrin S J. Effects of castration and exogenous testosterone supplementation in an animal model of penile erection. J Urol 1994; 151: 797–800
  • Hedon F. Anxiety and erectile dysfunction: A global approach to ED enhances results and quality of life. Int J Impot Res 2003; 15: S16–19, (Suppl 2)
  • Hernandez-Gonzalez M. Prepubertal genital grooming and penile erections in relation to sexual behavior of rats. Physiol Behav 2000; 71: 51–56
  • Kang K K, Choi S M, Ahn G J, Kwon J W, Kim W B. The effect of DA-8159 on corpus cavernosal smooth muscle relaxation and penile erection in diabetic rabbits. Urol Res 2004; 32: 107–111
  • Kirtikar K R, Basu B D. Indian Medicinal Plants, 3rd ed. International Book Distributor, Dehra Dun 1988; 1126–1127
  • Kushiro T, Takahashi A, Saito F, Otsuka Y, Soma M, Kurihara T, Satomura A, Saito T, Kanmatsuse K. Erectile dysfunction and its influence on quality of life in patients with essential hypertension. Am J Hypertens 2005; 18: 427–430
  • Latini D M, Penson D F, Colwell H H, Lubeck D P, Mehta S S, Henning J M, Lue T F. Psychological impact of erectile dysfunction: Validation of a new health related quality of life measure for patients with erectile dysfunction. J Urol 2002; 168: 2086–2091
  • Lau D H, Kommu S, Mikhailidis D P, Morgan R J, Mumtaz F H. Regarding the prevalence of hypertension, hyperlipidemia, diabetes mellitus and depression in men with erectile dysfunction. J Urol 2005; 173: 1050
  • Majewska M D. Neuronal actions dehydroepiandrosterone. Dehydroepiandrosterone (DHEA) and Aging, F L Bellino, R A Daynes, P J Hornsby, D H Lavrin, J E Nestler. New York Academy of Sciences, New York 1995; 111–120
  • Margolese H C. The male menopause and mood: Testosterone decline and depression in the aging male—is there a link?. J Geriatr Psychiatry Neurol 2000; 13: 93–101
  • Miller W L. Molecular biology of steroid hormone synthesis. Endocr Rev 1988; 9: 295–318
  • Mills T M, Reilly C M, Lewis R W. Androgens and penile erection: A review. J Androl 1996; 17: 633–638
  • Mills T M, Wiedmeier V T, Stopper V S. Androgen maintenance of erectile function in the rat penis. Biol Reprod 1992; 46: 342–348
  • Morales A, Heaton J P. Hormonal erectile dysfunction. Evaluation and management. Urol Clin North Am 2001; 28: 279–288
  • Mulhall J P, Valenzuela R, Aviv N, Parker M. Effect of testosterone supplementation on sexual function in hypogonadal men with erectile dysfunction. Urology 2004; 63: 348–352, discussion 352–353
  • Murray F T, Johnson R D, Sciadini M, Katovich M J, Rountree J, Jewett H. Erectile and copulatory dysfunction in chronically diabetic BB/WOR rats. Am J Physiol 1992; 263: E151–157
  • Neychev V K, Mitev V I. The aphrodisiac herb Tribulus terrestris. does not influence the androgen production in young men. J Ethnopharmacol 2005; 101: 319–323
  • OECD (Organization for Economic Co-operation and Development). Guidance Document on Acute Oral Toxicity Testing. Environment Directorate, OECD, Paris 2001; 1–24
  • Ottani A, Giuliani D, Ferrari F. Modulatory activity of sildenafil on copulatory behavior of both intact and castrated male rats. Pharmacol Biochem Behav 2002; 72: 717–722
  • Papatsoris A G, Korantzopoulos P G. Hypertension, antihypertensive therapy, and erectile dysfunction. Angiology 2006; 57: 47–52
  • Park S W, Lee C H, Shin D H, Bang N S, Lee S M. Effect of SA1, a herbal formulation, on sexual behavior and penile erection. Biol Pharm Bull 2006; 29: 1383–1386
  • Protich M, Tsvetkov D, Nalbanski B, Stanislavov R, Katsarova M. [Clinical trial of a tribestan preparation in infertile men]. Akush Ginekol (Sofiia) 1983; 22: 326–329
  • Rabkin J G, Wagner G J, Rabkin R. Testosterone therapy for human immunodeficiency virus-positive men with and without hypogonadism. J Clin Psychopharmacol 1999; 19: 19–27
  • Rampin O, Jerome N, Suaudeau C. Proerectile effects of apomorphine in mice. Life Sci 2003; 72: 2329–2336
  • Schiavi R C, White D, Mandeli J, Levine A C. Effect of testosterone administration on sexual behavior and mood in men with erectile dysfunction. Arch Sex Behav 1997; 26: 231–241
  • Seftel A D, Mack R J, Secrest A R, Smith T M. Restorative increases in serum testosterone levels are significantly correlated to improvements in sexual functioning. J Androl 2004; 25: 963–972
  • Tomova M, Gjulemetova R, Zarkova S, Peeva S, Pangarova T, Simova M. Steroidal saponins from Tribulus terrestris L. with a stimulating action on the sexual functions. International Conference of Chemistry and Biotechnology of Biologically Active Natural Products. RSC Publishing, Varna, Bulgaria 1981; 298–302
  • Utiger R D. Testosterone “fix”: Youth or consequences? Should we treat “male menopause”?. Health News 2003; 9: 3
  • Yildirim M K, Yildirim S, Utkan T, Sarioglu Y, Yalman Y. Effects of castration on adrenergic, cholinergic and nonadrenergic, noncholinergic responses of isolated corpus cavernosum from rabbit. Br J Urol 1997; 79: 964–70

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