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Research Article

Evaluation of selected indigenous medicinal plants from the western Himalayas for cytotoxicity and as potential cancer chemopreventive agents

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Pages 533-538 | Received 10 Jun 2008, Accepted 12 Aug 2008, Published online: 01 Jun 2009

References

  • Benson AM, Hunkeler MJ, Talalay P (1980): Increase of NAD(P)H: quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity. Proc Natl Acad Sci USA 77: 5216–5220.
  • Bharti AC, Aggarwal BB (2002): Nuclear factor-kappa B and cancer: its role in prevention and therapy. Biochem Pharmacol 64: 883–888.
  • Boone CW, Kelloff GJ, Malone WE (1990): Identification of candidate cancer chemopreventive agents and their evaluation in animal models and human clinical trials: a review. Cancer Res 50: 2–9.
  • Chen F, Castranova V, Shi XL (2001): New insights into the role of nuclear factor-kappa B in cell growth regulation. Am J Pathol 159: 387–397.
  • Conley BA, Egorin MJ, Tait N, Rosen DM, Sausville EA, Dover G, Fram RJ, Van Echo DA (1998): Phase I study of the orally administered butyrate prodrug, tributyrin, in patients with solid tumors. Clin Cancer Res 4: 629–634.
  • Cuendet M, Oteham CP, Moon RC, Pezzuto JM (2006): Quinone reductase induction as a biomarker for cancer chemoprevention. J Nat Prod 69: 460–463.
  • Dorai T, Aggarwal BB (2004): Role of chemopreventive agents in cancer therapy. Cancer Lett 215: 129–140.
  • Ghufran MA, Ghaffar SA, Qureshi RA (2007): Ethnobotanical study of the alpine-subalpine flora of Neelum Valley, Azad Jammu and Kashmir. Pak J Sci Ind Res 50: 278–283.
  • Goodman GE (1992): The clinical evaluation of cancer chemoprevention agents: defining and contrasting phase I, II, and III objectives. Cancer Res 52: 2752–2757.
  • Goodman SM, Ghafoor A (1992): The ethnobotany of southern Baluchistan, Pakistan, with particular reference to medicinal plants. Fieldiana Bot 31(5): 1–84.
  • Homhual S, Bunyapraphatsara N, Kondratyuk TP, Herunsalee A, Chaukul W, Pezzuto JM, Fong HHS, Zhang HJ (2006): Bioactive dammarane triterpenes from the mangrove plant Bruguiera gymnorrhiza. J Nat Prod 69, 421–424.
  • Kennelly EJ, Gerhäuser C, Song LL, Graham JG, Beecher CWW, Pezzuto JM, Kinghorn AD (1997): Induction of quinone reductase by withanolides isolated from Physalis philidelphica (tomatillos). J Agri Food Chem 45: 3771–3777.
  • Kondratyuk T, Pezzuto JM (2004): Natural product polyphenols of relevance to human health. Pharm Biol 42: 46–63.
  • Lippman SM, Lee JS, Lotan R, Hittelman W, Wargovich MJ, Hong WK (1990): Biomarkers as intermediate end points in chemoprevention trials. J Natl Cancer Inst 82: 555–560.
  • Maiti A, Cuendet M, Croy VL, Endringer DC, Pezzuto JM, Cushman M (2007): Synthesis and biological evaluation of (±)-abyssinone II and its analogues as aromatase inhibitors for chemoprevention of breast cancer. J Med Chem 50: 2799–2806.
  • Mi Q, Cui B, Silva GL, Lantvit D, Lim E, Chai H, You M, Hollingshead MG, Mayo JG, Kinghorn AD, Pezzuto JM (2001): Pervilleine A, a novel tropane alkaloid that reverses the multidrug-resistance phenotype. Cancer Res 61: 4030–4037.
  • Pezzuto JM, Kosmeder JW, Park EJ, Lee SK, Cuendet M, Gills J, Bhat K, Grubjesic S, Park HS, Mata-Greenwood E, Tan YM, Yu R, Lantvit DD, Kinghorn AD (2005): Characterization of natural product chemopreventive agents, in: G.J. Kelloff, E.T. Hawk, and C.C. Sigman (eds.) Cancer Chemoprevention, Volume 2: Strategies for Cancer Chemoprevention. Totowa, NJ, Humana Press, pp. 1–37.
  • Pezzuto JM, Kondratyuk TP, Shalaev E (2006): Cancer chemoprevention by wine polyphenols and resveratrol, in: W. Baer-Dubowska, A. Bartoszek, and D. Malejka-Giganti (eds.), Carcinogenic and Anticarcinogenic Food Components, Chapter 12. Boca Raton, FL, CRC Press, Taylor and Francis Group, pp. 239–258.
  • Prochaska HJ, Santamaria AB (1988): Direct measurement of NAD(P)H: quinine reductase from cells in microtiter wells: a screening assay for anticarcinogenic enzyme inducers. Anal Biochem 169: 328–336.
  • Qureshi RA, Ghufran MA (2005): Medicinal value of some important roses and allied species of northern areas of Pakistan, in: Hashmi M, ed., Pakistan Rose Annual, Islamabad, Pictorial Printers, pp. 24–29.
  • Riaz N, Nawaz SA, Mukhtar N, Malik A, Afza N, Ali S, Ullah S, Muhammad P, Choudhary MI (2007): Isolation and enzyme-inhibition studies of the chemical constituents from Ajuga bracteosa. Chem Biodivers 4: 72–83.
  • Salick J, Biun A, Martin G, Apin L, Beaman R (1999): Whence useful plants? A direct relationship between biodiversity and useful plants among the Dusun of Mt. Kinabalu. Biodiv Conserv 8: 797–818.
  • Schatzkin A, Freedman LS, Schiffman MH, Dawsey SM (1990): Validation of intermediate end points in cancer research. J Natl Cancer Inst 82: 1746–1752.
  • Sharma S, Stutzman JD, Kelloff GJ, Steele VE (1994): Screening of potential chemopreventive agents using biochemical markers of carcinogenesis. Cancer Res 54: 5848–5855.
  • Shinwari ZK, Watanabe T, Yousaf Y (2000): Medicinal plants of Pakistan: an overview, in: Proceedings of Nepal-Japan Joint Symposium on Conservation of Natural Medicinal Resources and their Utilization, Kathmandu, Nepal, 5-11 November 2000, pp. 279–285.
  • Song LL, Kosmeder JW, Lee SK, Gerhauser C, Lantvit D, Moon RC, Moriarty RM, Pezzuto JM (1999): Cancer chemopreventive activity mediated by 49-bromoflavone, a potent inducer of phase II detoxification enzymes. Cancer Res 59: 578–585.
  • Strasser-Weippl K, Goss PE (2005): Counteracting estrogen as breast cancer prevention, in: G.J. Kelloff, E.T. Hawk, and C.C. Sigman (eds.) Cancer Chemoprevention, Volume 2: Strategies for Cancer Chemoprevention. Totowa, NJ, Humana Press, pp. 249–264.
  • Wattenberg LW (1985): Chemoprevention of cancer. Cancer Res 45: 1–8.
  • Weinstein IB (1991): Cancer prevention: recent progress and future opportunities. Cancer Res 51: 5080–5085.
  • Wu K, Kim HT, Rodriquez JL, Hilsenbeck SG, Mohsin SK, Xu XC, Lamph WW, Kuhn JG, Green JE, Brown PH (2002): Suppression of mammary tumorigenesis in transgenic mice by the RXR-selective retinoid, LGD1069. Cancer Epidemiol Biomark Prev 11: 467–474.
  • You M, Wickramaratne DB, Silva GL, Chai H, Chagwedera TE, Farnsworth NR, Cordell GA, Kinghorn AD, Pezzuto JM (1995): Roemerine, an aporphine alkaloid from Annona senegalensis that reverses the multidrug-resistance phenotype with cultured cells. J Nat Prod 58: 598–604.

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