Antidiarrheal, antisecretory, and bronchodilatory activities of Hypericum perforatum

References

• Baquar SR (1989): Medicinal and Poisonous Plants of Pakistan. Karachi, Printas, pp. 235–236.
   Google Scholar
• Barnes J, Anderson LA, Phillipson JD (2001): St. John’s wort (Hypericum perforatum): A review of its chemistry, pharmacology and clinical properties. J Pharm Pharmacol 53: 583–600.
   PubMed Web of Science ®Google Scholar
• Barnes PJ (2006): Drugs for asthma. Br J Pharmacol 147: S297–S303.
   PubMed Web of Science ®Google Scholar
• Bombardelli E, Morazzoni P (1995): Hypericum perforatum. Fitoterapia 31: 43–58.
   Google Scholar
• Borelli F, Capasso F, Capasso R, Ascione V, Aviello G, Longo R, Izzo AA (2006): Effect of Boswellia serrata on intestinal motility in rodents: Inhibition of diarrhoea without constipation. Br J Pharmacol 148: 553–560.
   PubMedGoogle Scholar
• Capasso R, Izzo AA, Borelli F, Russo A, Sautebin L, Pinto A, Capasso F, Mascolo N (2002): Effect of piperine, the active ingredient of black pepper on intestinal secretion in mice. Life Sci 71: 2311–2317.
   PubMed Web of Science ®Google Scholar
• Channa S, Dar A, Ahmed S, Atta-ur-Rahman (2005): Evaluation of Alstonia scholaris leaves for broncho-vasodilatory activity. J Ethnopharmacol 97: 469–476.
   PubMed Web of Science ®Google Scholar
• Croci T, Landi M, Elmonds-Alt X, Le Fur G, Maffrand JP, Manara L (1997): Role of tachykinins in castor oil-induced diarrhea in rats. Br J Pharmacol 121: 375–380.
   PubMed Web of Science ®Google Scholar
• Dar A, Channa S (1997): Bronchodilatory and cardiovascular effects of an ethanol extract of Bacopa monniera in anaesthetized rats. Phytomedicine 4: 319–323.
   PubMed Web of Science ®Google Scholar
• Das AK, Mandal SC, Banarjee SK, Sinha S, Das J, Saha BP, Pal M (1999): Studies on antidiarrheal activity of Punica granatum seed extract in rats. J Ethnopharmacol 68: 205–208.
   PubMed Web of Science ®Google Scholar
• Di Carlo G, Autore G, Izzo AA, Maiolino P, Mascolo N, Viola P, Diurno MV, Capasso F (1993): Inhibition of intestinal motility and secretion by flavonoids in mice and rats: structure-activity relationships. J Pharm Pharmacol 45: 1054–1059.
   PubMedGoogle Scholar
• Duke JA (1992): Handbook of Phytochemical Constituents of GRAS Herbs and Other Economical Plants. London, CRC Press, pp. 302–303.
   Google Scholar
• Gaginella TS, Phillips SF (1975): Ricinoleic acid: Current view of ancient oil. Dig Dis Sci 20: 1171–1177.
   Web of Science ®Google Scholar
• Ghayur MN, Khan H, Gilani AH (2007): Antispasmodic, bronchodilator and vasodilator activites of (+)-catechin, a naturally occurring flavonoid. Arch Pharm Res 30: 970–975.
   PubMed Web of Science ®Google Scholar
• Gilani AH, Khan A, Subhan F, Khan M (2005a): Antispasmodic and bronchodilator activities of St. John’s wort are putatively mediated through dual inhibition of calcium influx and phosphodiesterase. Fund Clin Pharmacol 19: 695–705.
   PubMed Web of Science ®Google Scholar
• Gilani AH, Ghayur MN, Khalid A, Zaheer-ul-Haq Q, Choudhary MI, Atta-ur-Rahman (2005b): Presence of antispasmodic, antidiarrhoeal, antisecretory, calcium antagonist and acetylcholinesterase inhibitory steroidal alkaloids in Sarcocca saligna. Planta Med 71: 1–6.
   Google Scholar
• Gilani AH, Khan A, Ghayur MN, Ali SF, Herzig JW (2006): Antispasmodic effect of Rooibos tea (Aspalathus linearis) is mediated predominantly through K+ channel activation. Basic Clin Pharmacol Toxicol 99: 365–373.
   PubMed Web of Science ®Google Scholar
• Gilani AH, Khan A, Raoof M, Ghayur MN, Siddiqui BS, Vohra W, Begum S (2008a): Gastrointestinal, selective airways and urinary bladder relaxant effects of Hyoscyamus niger are mediated through dual blockade of muscarinic receptors and Ca++ channels. Fund Clin Pharmacol 22: 87–99.
   PubMed Web of Science ®Google Scholar
• Gilani AH, Khan A, Ali T, Ajmal S (2008b): Mechanisms underlying the antispasmodic and bronchodilatory properties of Terminalia bellerica fruit. J Ethnopharmacol 116: 528–538.
   PubMed Web of Science ®Google Scholar
• Girzu M, Carnat A, Privat AM, Fialip J, Carnat AP, Lamaison JL (1997): Sedative activity in mice of a hydroalcohol extract of Hypericum perforatum. Phytother Res 11: 395–397.
   Google Scholar
• Harrer G, Schmidt U, Kuhn U, Biller A (1999): Comparison of equivalence between the St. John’s wort extract LoHyp-57 and fluoxetine. Arzneimittelforschung 49: 289–296.
   PubMed Web of Science ®Google Scholar
• Heinrich M, Rimpler H, Barrera NA (1992): Indigenous phytotherapy of gastrointestinal disorders in a low and mix community (Oaxaca, Mexico): Ethnopharmacologic evaluation. J Ethnopharmacol 36: 63–80.
   PubMed Web of Science ®Google Scholar
• Hu ZP, Yang XX, Chan SY, Xu AL, Duan W, Zhu YZ, Sheu FS, Boelsterli UA, Chan E, Zhang Q, Wang JC, Ee PL, Koh HL, Huang M, Zhou SF (2006): St. John’s wort attenuates irinotecan-induced diarrhea via down-regulation of intestinal pro-inflammatory cytokines and inhibition of intestinal epithelial apoptosis. Toxicol Appl Pharmacol 216: 225–237.
   PubMed Web of Science ®Google Scholar
• Iwao I, Terada Y (1962): On the mechanism of diarrhea due to castor oil. Jpn J Pharmacol 12: 137–145.
   PubMedGoogle Scholar
• Izzo AA, Mascolo N, Carlo GD, Capasso F (1994): NG-nitro-l-arginine methyl ester modulates intestinal secretion and motility produced by carbachol. Eur J Pharmacol 271: 31–35.
   PubMedGoogle Scholar
• Josey ES, Tackett RL (1999): St. John’s wort: A new alternative for depression. Int J Clin Pharmacol Ther 37: 111–119.
   PubMed Web of Science ®Google Scholar
• Keles O, Bkirel T, Ak S, Alpmar A (2001): The antibacterial activity of some plants used for medicinal purposes against pathogens of veterinary importance. Fol Veterinaria 45: 22–25.
   Google Scholar
• Khalifa AE (2001): Hypericum perforatum as a nootropic drug: enhancement of retrieval memory of a passive avoidance conditioning paradigm in mice. J Ethnopharmacol 76: 49–57.
   PubMedGoogle Scholar
• Khan A, Gilani AH (2006): Selective bronchodilatory effect of Rooibos tea (Aspalathus linearis) and its flavonoid: chrysoeriol. Eur J Nutr 45: 463–469.
   PubMed Web of Science ®Google Scholar
• Khosa RL, Bhatia N (1982): Antifungal effect of Hypericum perforatum. J Sci Res Plants Med 3: 49–50.
   Google Scholar
• Kumar V, Jaiswal AK, Singh PN, Bhattacharya SK (2000): Anxiolytic activity of Indian Hypericum perforatum: an experimental study. Indian J Exp Biol 38: 36–41.
   PubMedGoogle Scholar
• Kumar V, Singh PN, Bhattacharya SK (2001): Anti-inflammatory and analgesic activity of indian Hypericum perforatum. Indian J Exp Biol 39: 339–343.
   PubMedGoogle Scholar
• Mahady GB, Fong HS, Fransworth NR (2001): Botanical Dietary Supplements: Quality, Safety and Efficacy. Lisse, Swets and Zeitlinger, pp. 245–261.
   Google Scholar
• Mateo SCC, Prado B, Rabanal RM (2002): Antidepressant effects of the methanol extract of several Hypericum species from the Canary Islands. J Ethnopharmacol 79: 119–127.
   PubMedGoogle Scholar
• McKenna DJ, Jones K, Hughes K, Humphrey S (2002): Botanical Medicines: The Desk Reference for Major Herbal Supplements, 2nd ed. New York, Haworth Herbal Press, pp. 923–986.
   Google Scholar
• Miller LG, Murray WJ (1998): Herbal Medicinals: A Clinician’s Guide. Binghamton, Pharmaceutical Products Press, pp. 219–220.
   Google Scholar
• Muller WE (2003): Current St. John’s wort research from mode of action to clinical efficacy. Pharmacol Res 47: 101–109.
   PubMed Web of Science ®Google Scholar
• Nadkarni KM (1976): Indian Materia Medica, 3rd ed. Bombay, Popular Prakashan, pp. 670–673.
   Google Scholar
• Nahrstedt A, Butterweck V (1997): Biologically active and other chemical constituents of the Hypericum perforatum. Pharmacopsychiatry 30: 129–134.
   PubMed Web of Science ®Google Scholar
• National Research Council (1996): Guide for the Care and Use of Laboratory Animals. Washington, National Academy Press, pp. 1–7.
   Google Scholar
• Ozturk Y, Aydin S, Baser KHC, Kirmer N, Ozturk KN (1992): Hepatoprotective activity of Hypericum perforatum alcoholic extract in rodents. Phytother Res 6: 44–46.
   Google Scholar
• Ozturk Y, Aydin S, Beis R, Baser KHC, Berberoglu H (1996): Effects of Hypericum perforatum and Hypericum calycinum extracts on the central nervous system in mice. Phyotmedicine 3: 139–146.
   PubMed Web of Science ®Google Scholar
• Pietta P (1998): Flavonoids in medicinal plants. In: Rice-Evans CV, Packer L, eds., Flavonoids in Health and Disease. New York, Marcel Dekker, pp. 61–110.
   Google Scholar
• Rabe KF, Magnussen H, Dent G (1995): Theophylline and selective PDE inhibitors as bronchodilators and smooth muscle relaxants. Eur Resp J 8: 637–642.
   PubMed Web of Science ®Google Scholar
• Reynolds IJ, Gould RJ, Snyder SH (1984): Loperamide: blockade of calcium channels as a mechanism for antidiarrheal effects. J Pharmacol Exp Ther 231: 628–632.
   PubMed Web of Science ®Google Scholar
• Sanmugapriya E, Venkataraman S (2006): Toxicological investigations on Strychnos potatorum seeds in experimental models. J Health Sci 52: 339–343.
   Google Scholar
• Scratcherd T, Grundy D (1984): The physiology of intestinal motility and secretions. Br J Anesthesiol 56: 3–18.
   PubMedGoogle Scholar
• Serkedjieva J, Manolova N, Zgorniak-Nowosielska I, Zawilinsata B, Grzybek J (1990): Anti-viral activity of the infusion (SHS 174) from flowers of Sambucus nigra, aerial parts of Hypericum perforatum and roots of Saponaria officinalis against influenza and herpes simplex virus. Phytother Res 4: 97–100.
   Web of Science ®Google Scholar
• Shibayama Y, Kawachi A, Onimaru S, Tokunaga J, Ikeda R, Nishida K, Kuchiiwa S, Nakagawa S, Takamura N, Motoya T, Takeda Y, Yamada K (2007): Effects of pre-treatment with St. John’s wort on nephrotoxicity of cisplatin in rats. J Ethnopharmacol 81: 103–108.
   Google Scholar
• Sopory S, Kaur T, Visweswariah SS (2004): The cGMP-binding, cGMP-specific phosphodiesterase (PDE5): INTESTINAL cell expression, regulation and role in fluid secretion. Cell Signal 16: 681–692.
   PubMedGoogle Scholar
• Tripathi YB, Pandey E (1999): Role of alcholic extract of shoots of Hypericum perforatum on lipid peroxidation and various species of free radical in rats. Indian J Exp Biol 37: 567–571.
   PubMedGoogle Scholar
• Weiss RF (1988): Herbal Medicine. Beaconsfield, Beaconsfield Publisher, p. 318.
   Google Scholar
• Wheatley D (1998): Hypericum extract potential in the treatment of depression. CNS Drugs 9: 431–440.
   Google Scholar
• Williamson EM, Okpako DT, Evans FJ (1998): Selection, Preparation and Pharmacological Evaluation of Plant Material, Vol. 1. Chichester, John Wiley & Sons, pp. 15–23.
   Google Scholar
• Woelk H (2000): Comparison of St. John’s wort and imipramine for treating depression: randomized controlled trial. Br Med J 321: 536–539.
   PubMed Web of Science ®Google Scholar
• Wyk BV, Oudtshoorn BV, Gericke N (2002): Medicinal Plants of South Africa. Pretoria, Briza Publications, pp. 48–49.
   Google Scholar