Antioxidant, anti-inflammatory and anti-septic potential of phenolic acids and flavonoid fractions isolated from Lolium multiflorum

References

• Ashraf A, Sarfraz RA, Rashid MA, Mahmood A, Shahid M, Noor N. 2016. Chemical composition, antioxidant, antitumor, anticancer and cytotoxic effects of Psidium guajava leaf extracts. Pharm Biol. 54:1971–1981.
   PubMed Web of Science ®Google Scholar
• Baek JA, Son YO, Fang M, Lee YJ, Cho HK, Whang WK, Lee JC. 2011. Catechin-7-O-β-d-glucopyranoside scavenges free radicals and protects human B lymphoma BJAB cells on H2O2-mediated oxidative stress. Food Sci Biotechnol. 20:151–158.
   Web of Science ®Google Scholar
• Blanque R, Meakin C, Millet S, Gardner CR. 1996 . Hypothermia as an indicator of the acute effects of lipopolysaccharides: comparison with serum levels of IL1 beta, IL6 and TNF alpha. Gen Pharmacol. 27:973–977.
   PubMedGoogle Scholar
• Bouriche H, Kada S, Assaf AM, Senator A, Gül F, Dimertas I. 2016. Phytochemical screening and anti-inflammatory properties of Algerian Hertia cheirifolia methanol extract. Pharm Biol. 54:2584–2590.
   PubMed Web of Science ®Google Scholar
• Bradford MM. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 72:248–254.
   PubMed Web of Science ®Google Scholar
• Cheng Q, Wang Z, Ma R, Chen Y, Yan Y, Miao S, Jiao J, Cheng X, Kong L, Ye D. 2016. Lipoxin A4 protects against lipopolysaccharide-induced sepsis by promoting innate response activator B cells generation. Int Immunopharmacol. 39:229–235.
   PubMed Web of Science ®Google Scholar
• Choi KC, Hwang JM, Bang SJ, Kim BT, Kim DH, Chae M, Lee SA, Choi GJ, Kim DH, Lee JC. 2013. Chloroform extract of alfalfa (Medicago sativa) inhibits lipopolysaccharide-induced inflammation by downregulating ERK/NF-κB signaling and cytokine production. J Med Food. 16:410–420.
   PubMed Web of Science ®Google Scholar
• Cuevas Montilla E, Hillebrand S, Antezana A, Winterhalter P. 2011. Soluble and bound phenolic compounds in different Bolivian purple corn (Zea mays L.) cultivars. J Agric Food Chem. 59:7068–7074.
   PubMed Web of Science ®Google Scholar
• Doyle SL, O'Neill LA. 2006 . Toll-like receptors: from the discovery of NFkappaB to new insights into transcriptional regulations in innate immunity. Biochem Pharmacol. 72:1102–1113.
   PubMed Web of Science ®Google Scholar
• Erel SB, Karaalp C, Bedir E, Kaehlig H, Glasl S, Khan S, Krenn L. 2011. Secondary metabolites of Centaurea calolepis and evaluation of cnicin for anti-inflammatory, antioxidant, and cytotoxic activities. Pharm Biol. 49:840–849.
   PubMed Web of Science ®Google Scholar
• Fang M, Lee SY, Park SM, Choi KC, Lee YJ, Cho HK, Cho SW, Whang WK, Lee JC. 2011. Anti-inflammatory potential of Phaseolus calcaratus Roxburgh, a oriental medicine, on LPS-stimulated RAW 264.7 macrophages. J Pharm Pharmacol. 63:120–128.
   PubMed Web of Science ®Google Scholar
• Ferretti G, Bacchetti T, Belleggia A, Neri D. 2010. Cherry antioxidants: from farm to table. Molecules. 15:6993–7005.
   PubMed Web of Science ®Google Scholar
• Firuzi O, Miri R, Tavakkoli M, Saso L. 2011. Antioxidant therapy: current status and future prospects. Curr Med Chem. 18:3871–3888.
   PubMed Web of Science ®Google Scholar
• Gaestel M, Mengel A, Bothe U, Asadullah K. 2007. Protein kinases as small molecule inhibitor targets in inflammation. Curr Med Chem. 14:2214–2234.
   PubMed Web of Science ®Google Scholar
• Gotoh N, Niki E. 1992. Rates of interactions of superoxide with vitamin E, vitamin C and related compounds as measured by chemiluminescence. Biochim Biophys Acta. 1115:201–207.
   PubMed Web of Science ®Google Scholar
• Halliwell B, Gutteridge JMC, Aruoma OI. 1987 . The deoxyribose method: a simple test-tube assay for determination of rate constants for reactions of hydroxyl radicals. Anal Biochem. 165:215–219.
   PubMed Web of Science ®Google Scholar
• Hu C, Kitts DD. 2000. Studies on the antioxidant activity of Echinacea root extract. J Agric Food Chem. 48:1466–1472.
   PubMed Web of Science ®Google Scholar
• Hwang JM, Choi KC, Bang SJ, Son YO, Kim BT, Kim DH, Choi GJ, Kim DH, Shi X, Lee JC. 2013. Anti-oxidant and anti-inflammatory properties of methanol extracts from various crops. Food Sci Biotechnol. 22:265–272.
   Web of Science ®Google Scholar
• Ilavenil S, Arasu MV, Lee JC, Kim DH, Vijayakumar M, Lee KD, Choi KC. 2014. Positive regulations of adipogenesis by Italian ryegrass [Lolium multiflorum] in 3T3-L1 cells. BMC Biotechnol. 14:54
   PubMed Web of Science ®Google Scholar
• Jiménez-Suárez V, Nieto-Camacho A, Jiménez-Estrada M, Alvarado Sánchez B. 2016 . Anti-inflammatory, free radical scavenging and alpha-glucosidase inhibitory activities of Hamelia patens and its chemical constituents. Pharm Biol. 54:1822–1830.
   PubMed Web of Science ®Google Scholar
• Jomova K, Valko M. 2011. Advances in metal-induced oxidative stress and human disease. Toxicology. 283:65–87.
   PubMed Web of Science ®Google Scholar
• Joubert J, Malan SF. 2011. Novel nitric oxide synthase inhibitors: a patent review. Expert Opin Ther Pat. 21:537–560.
   PubMed Web of Science ®Google Scholar
• Kamiyama M, Shibamoto T. 2012. Flavonoids with potent antioxidant activity found in young green barley leaves. J Agric Food Chem. 60:6260–6267.
   PubMed Web of Science ®Google Scholar
• Kobayashi Y. 2010. The regulatory role of nitric oxide in proinflammatory cytokine expression during the induction and resolution of inflammation. J Leukoc Biol. 88:1157–1162.
   PubMed Web of Science ®Google Scholar
• Kotanidou A, Xagorari A, Bagli E, Kitsanta P, Fotsis T, Papapetropoulos A, Roussos C. 2002 . Luteolin reduces lipopolysaccharide-induced lethal toxicity and expression of proinflammatory molecules in mice. Am J Respir Crit Care Med. 165:818–823.
   PubMed Web of Science ®Google Scholar
• Lee JC, Kim HR, Kim J, Jang YS. 2002. Antioxidant property of an ethanol extract of the stem of Opuntia ficus-indica var. saboten. J Agric Food Chem. 50:6490–6496.
   PubMed Web of Science ®Google Scholar
• Lee JC, Lim KT, Jang YS. 2002. Identification of Rhus verniciflua Stokes compounds that exhibit free radical scavenging and anti-apoptotic properties. Biochim Biophys Acta. 1570:181–191.
   PubMed Web of Science ®Google Scholar
• Lee JC, Son YO, Pratheeshkumar P, Shi X. 2012. Oxidative stress and metal carcinogenesis. Free Radic Biol Med. 53:742–757.
   PubMed Web of Science ®Google Scholar
• Li Q, Bao F, Zhi D, Liu M, Yan Q, Zheng X, Ren L, Cong S, Li Y, Cao G. 2016. Lipopolysaccharide induces SBD-1 expression via the p38 MAPK signaling pathway in ovine oviduct epithelial cells. Lipids Health Dis. 15:127
   PubMed Web of Science ®Google Scholar
• Mates JM, Sanchez-Jimenez FM. 2000. Role of reactive oxygen species in apoptosis: implications for cancer therapy. Int J Biochem Cell Biol. 32:157–170.
   PubMed Web of Science ®Google Scholar
• Quinde-Axtell Z, Baik BK. 2006. Phenolic compounds of barley grain and their implication in food product discoloration. J Agric Food Chem. 54:9978–9984.
   PubMed Web of Science ®Google Scholar
• Patil NK, Bohannon JK, Sherwood ER. 2016. Immunotherapy: a promising approach to reverse sepsis-induced immunosuppression. Pharmacol Res. 111:688–702.
   PubMed Web of Science ®Google Scholar
• Rao SR, Ravishankar GA. 2002. Plant cell cultures: chemical factories of secondary metabolites. Biotechnol Adv. 20:101–153.
   PubMed Web of Science ®Google Scholar
• Shin KM, Shen L, Park SJ, Jeong JH, Lee KT. 2009 . bis-(3-Hydroxyphenyl) diselenide inhibits LPS-stimulated iNOS and COX-2 expression in RAW 264.7 macrophage cells through the NF-kappaB inactivation. J Pharm Pharmacol. 61:479–486.
   PubMed Web of Science ®Google Scholar
• Son YO, Jang YS, Heo JS, Chung WT, Choi KC, Lee JC. 2009. Apoptosis-inducing factor plays a critical role in caspase-independent, pyknotic cell death in hydrogen peroxide-exposed cells. Apoptosis. 14:796–808.
   PubMed Web of Science ®Google Scholar
• Sun JY, You CY, Dong K, You HS, Xing JF. 2016. Anti-inflammatory, analgesic and antioxidant activities of 3,4-oxo-isopropylidene-shikimic acid. Pharm Biol. 54:2282–2287.
   PubMed Web of Science ®Google Scholar
• Tunin LM, Borghi FB, Nogueira AC, Higachi L, Barbosa DS, Baesso ML, Hernandes L, Diniz A, Truiti Mda C. 2016. Employing photoacoustic spectroscopy in the evaluation of the skin permeation profile of emulsion containing antioxidant phenolic-rich extract of Melochia arenosa. Pharm Biol. 54:139–145.
   PubMed Web of Science ®Google Scholar
• Valan Arasu M, Ilavenil S, Kim DH, Gun Roh S, Lee JC, Choi KC. 2014. In vitro and in vivo enhancement of adipogenesis by Italian ryegrass (Lolium multiflorum) in 3T3-L1 cells and mice. PLoS One. 9:e85297
   PubMed Web of Science ®Google Scholar
• von Harsdorf R, Li PF, Dietz R. 1999 . Signaling pathways in reactive oxygen species-induced cardiomyocyte apoptosis. Circulation. 99:2934–2941.
   PubMed Web of Science ®Google Scholar
• Wang YH, Li TH, Wu BQ, Liu H, Shi YF, Feng DY. 2015. Protective effects of caffeoylxanthiazonoside isolated from fruits of Xanthium strumarium on sepsis mice. Pharm Biol. 53:1367–1371.
   PubMed Web of Science ®Google Scholar
• Wu MJ, Wang L, Ding HY, Weng CY, Yen JH. 2004 . Glossogyne tenuifolia acts to inhibit inflammatory mediator production in a macrophage cell line by downregulating LPS-induced NF-kappa B. J Biomed Sci. 11:186–199.
   PubMed Web of Science ®Google Scholar
• Yamaura K, Nakayama N, Shimada M, Bi Y, Fukata H, Ueno K. 2012. Antidepressant-like effects of young green barley leaf (Hordeum vulgare L.) in the mouse forced swimming test. Pharmacognosy Res. 4:22–26.
   PubMedGoogle Scholar
• Yu JY, Zheng ZH, Son YO, Shi X, Jang YO, Lee JC. 2011. Mycotoxin zearalenone induces AIF- and ROS-mediated cell death through p53- and MAPK-dependent signaling pathways in RAW264.7 macrophages. Toxicol In Vitro. 25:1654–1663.
   PubMed Web of Science ®Google Scholar
• Zilić S, Serpen A, Akıllıoğlu G, Gökmen V, Vančetović J. 2012. Phenolic compounds, carotenoids, anthocyanins, and antioxidant capacity of colored maize (Zea mays L.) kernels. J Agric Food Chem. 60:1224–1231.
   PubMed Web of Science ®Google Scholar