Bioactive compounds from Hypericum humifusum and Hypericum perfoliatum: inhibition potential of polyphenols with acetylcholinesterase and key enzymes linked to type-2 diabetes

References

• Agostinis P, Vantieghem A, Merlevede W, De Witte PAM. 2002. Hypericin in cancer treatment: more light on the way. Int J Biochem Cell Biol. 34:221–241.
   PubMed Web of Science ®Google Scholar
• Ali M, Arfan M, Ahmad H, Zaman K, Khan F, Amarowicz R. 2011. Comparative antioxidant and antimicrobial activities of phenolic compounds extracted from five Hypericum species. Food Technol Biotechnol. 49:205–213.
   Web of Science ®Google Scholar
• Avato P, Raffo F, Guglielmi G, Vitali C, Rosato A. 2004. Extracts from St John’s Wort and their antimicrobial activity. Phytother Res. 18:230–232.
   PubMed Web of Science ®Google Scholar
• Ayan AK, Cırak C, Kevseroglu K, Mzen T. 2004. Hypericin in some Hypericum species from Turkey. Asian J Plant Sci. 3:200–202.
   Google Scholar
• Benkiki N, Kabouche Z, Tillequin F, Verite P, Chosson E, Seguin E. 2003. A new polyisoprenylated phloroglucinol derivative from Hypericum perfoliatum (Clusiaceae). Z Nat Forsch. 58:655–658.
   PubMed Web of Science ®Google Scholar
• Butterwerck V, Jürgenliemk G, Nahrstedt A, Winterhoff H. 2000. Flavonoids from Hypericum perforatum show antidepressant activity in the forced swimming test. Planta Med. 66:3–6.
   PubMed Web of Science ®Google Scholar
• Cakir A, Mavi A, Yildirim A, Duru ME, Harmandar M, Kazaz C. 2003. Isolation and characterization of antioxidant phenolic compounds from the aerial parts of Hypericum hyssopifolium L. by activity-guided fractionation. J Ethnopharmacol. 87:73–83.
   PubMed Web of Science ®Google Scholar
• Capocasa F, Scalzo J, Mezzetti B, Battino M. 2008. Combining quality and antioxidant attributes in the strawberry: The role of genotype. Food Chem. 111:872–878.
   Web of Science ®Google Scholar
• Cardile V, Russo A, Formisano C, Rigano D, Senatore F, Arnold NA, Piozzi F. 2009. Essential oils of Salvia bracteata and Salvia rubifolia from Lebanon: chemical composition, antimicrobial activity and inhibitory effect on human melanoma cells. J Ethnopharmacol. 126:265–272.
   PubMed Web of Science ®Google Scholar
• Çirak C, Radusiene J, Janulis V, Ivanauskas L. 2007. Secondary metabolites in Hypericum perfoliatum: variation among plant parts and phenological stages. Bot Helv. 117:29–36.
   Web of Science ®Google Scholar
• Çirak C. 2007. Seed germination protocols for ex situ conservation of some Hypericum species from Turkey. Am J Plant Physiol. 2:287–294.
   Google Scholar
• Conforti F, Stati GA, Tundis R, Bianchi A, Agrimonti C, Sacchetti G, Andreotti E, Menichini F, Poli F. 2005. Comparative chemical composition and variability of biological activity of methanolic extracts from Hypericum perforatum L. Nat Prod Res. 19:295–303.
   PubMed Web of Science ®Google Scholar
• Couladis M, Baziou P, Petrakis PV, Harvala C. 2001. Essential oil composition of Hypericum perfoliatum L. growing in different locations in Greece. Flavour Fragr J. 16:204–206.
   Web of Science ®Google Scholar
• Del Monte D, De Martino L, Marandino A, Fratianni F, Nazzaro F, De Feo V. 2015. Phenolic content, antimicrobial and antioxidant activities of Hypericum perfoliatum L. Ind Crops Prod. 74:342–347.
   Web of Science ®Google Scholar
• Dinis TC, Madeira VM, Almeida LM. 1994. Action of phenolic derivatives (acetaminophen, salicylate, and 5-amino salicylate) as inhibitors of membrane lipid peroxidation and as peroxyl radical scavengers. Arch Biochem Biophys. 315:161–169.
   PubMed Web of Science ®Google Scholar
• Djeridane A, Yousfi M, Nadjemi B, Boutassouna D, Stocker P, Vidal N. 2006. Antioxidant activity of some Algerian medicinal plants extracts containing phenolic compounds. Food Chem. 97:654–660.
   Web of Science ®Google Scholar
• Dong HQ, Li M, Zhu F, Liu FL, Huang JB. 2012. Inhibitory potential of trilobatin from Lithocarpus polystachyus Rehd against alpha-glucosidase and alpha-amylase linked to type 2 diabetes. Food Chem. 130:261–266.
   Web of Science ®Google Scholar
• Fritz D, Venturi C, Cargnin S, Schripsema J, Roehe P, Montan ha J, Von Poser G. 2007. Herpes virus inhibitory substances from Hypericum connatum Lam, a plant used in southern Brazil to treat oral lesions. J Ethnopharmacol. 113:517–520.
   PubMed Web of Science ®Google Scholar
• Gardeli C, Vassiliki P, Athanasios M, Kibouris T, Komaitis M. 2008. Essential oil composition of Pistacia lentiscus L. and Myrtus communis: Evaluation of antioxidant capacity of methanolic extracts. Food Chem. 107:1120–1130.
   Web of Science ®Google Scholar
• Gibbons S, Ohlendorf B, Johnsen I. 2002. The genus Hypericum-a valuable resource of anti-Staphylococcal leads. Fitoterapia. 73:300–304.
   PubMed Web of Science ®Google Scholar
• Gray DM. 1995. Carbohyrate digestion and absroption-role of small intestine. New Engl J Med. 29:1225–1230.
   Google Scholar
• Gulam MH, Paras Nath S, Vikas K. 2009. Beneficial effects of a standardized Hypericum perforatum extract in rats with experimentally induced hyperglycemia. Drug Discov Ther. 3:215–220.
   PubMedGoogle Scholar
• Hatano T, Kagawa H, Yasuhara T, Okuda T. 1988. Two new flavonoids and other constituents in licorice root: their relative astringency and radical scavenging effects. Chem Pharm Bull. 36:1090–2097.
   Web of Science ®Google Scholar
• Hofrichter J, Krohn M, Schumacher T, Lange C, Feistel B, Walbroel B, Heinze H-J, Crockett S, Sharbel T, Pahnke FJ. 2013. Reduced Alzheimer’s disease pathology by St. John’s wort treatment is independent of hyperforin and facilitated by ABCC1 and microglia activation in mice. Curr Alzheimer Res. 10:1057–1069.
   PubMed Web of Science ®Google Scholar
• Jacobson JM, Feinman L, Liebes L, Ostrow N, Koslowski V, Tobia A, Cabana BE, Lee D, Spritzler J, Prince AM. 2001. Pharmacokinetics, safety, and antiviral effects of hypericin, a derivative of St John’s wort plant, in patients with chronic hepatitis C virus infection. Antimicrob Agents Chemother. 45:517–524.
   PubMed Web of Science ®Google Scholar
• Kamatou GPP, Van Zyl RL, Davids H, Van Heerden FR, Lourens ACU, Viljoen AM. 2008. Antimalarial and anticancer activities of selected South African Salvia species and isolated compounds from S. radula. S Afr J Bot. 74:238–243.
   Web of Science ®Google Scholar
• Kizil G, Toker Z, Ozen HC, Aytekin C. 2004. The antimicrobial activity of essential oils of Hypericum scabrum, Hypericum scabroides and Hypericum triquetrifolium. Phytother Res. 18:339–341.
   PubMed Web of Science ®Google Scholar
• Le Floc’h E. 1983. Contribution à une étude ethnobotanique de la flore tunisienne. Imp.Off. Rep. Tunisia.
   Google Scholar
• Matzk F, Hammer K, Shubert I. 2003. Coevolution of apomixis and genome size within the genus Hypericum. Sex Plant Reprod. 16:52–58.
   Web of Science ®Google Scholar
• Mukherjee PK, Kumar V, Mal M, Houghton PJ. 2007. Acetylcholinesterase inhibitors from plants. Phytomedicine. 14:289–300.
   PubMed Web of Science ®Google Scholar
• Mukherjee PK, Wahile A, Nazeer AKFH, Rajan S. 2003. Hypericum source of natural antimicrobials. Oriental Pharm Experim Med. 3:111–122.
   Google Scholar
• NCCLS. 2009a. Methods for dilution Antimicrobial susceptibility tests for bacteria that grow aerobically. Approved Standard M7-A8, Eighth Edition, Wayne, PA.
   Google Scholar
• NCCLS. 2009b. Performance standard antimicrobial disc susceptibility testing, 10th Edition, M02 A10, Wayne, PA.
   Google Scholar
• Nithiyanantham S, Selvakumar S, Siddhuraju P. 2012. Total phenolic content and antioxidant activity of two different solvent extracts from raw and processed legumes, Cicer arietinum L. and Pisum sativum L. J Food Compos Anal. 27:52–60.
   Web of Science ®Google Scholar
• Nogueira T, Marcelo-Curto MJ, Cristina Figueiredo A, Barroso Jose G, Pedro LG, Rubiolo P, Bicchi C. 2008. Chemotaxonomy of Hypericum genus from Portugal: Geographical distribution and essential oils composition of Hypericum perfoliatum, Hypericum humifusum, Hypericum linarifolium and Hypericum pulchrum. Biochem Syst Ecol. 36:40–50.
   Web of Science ®Google Scholar
• Nogueira T, Medeiros MA, Marcelo-Curto MJ, García-Pérez BE, Luna-Herrera J, Céu Costa M. 2013. Profile of antimicrobial potential of fifteen Hypericum species from Portugal. Ind Crops Prod. 47:126–131.
   Web of Science ®Google Scholar
• Okeke MI, Iroegbu CU, Eze EN, Okol AS, Esimone CO. 2001. Evaluation of extracts of the root of Landolphia owerrience for antibacterial activity. J Ethnopharmacol. 78:119–127.
   PubMed Web of Science ®Google Scholar
• Patocka J. 2003. The chemistry, pharmacology, and toxicology of the biologically active constituents of the herb Hypericum perforatum L. J Appl Biomed. 1:61–73.
   Google Scholar
• Pottier-Alapetite G. 1979. Flore de la Tunisie: Angiospermes dicotylédones, Apétales-Dialypétales. I.O.R: Tunisie; pp. 654.
   Google Scholar
• Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C. 1999. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radic Biol Med. 26:1231–1237.
   PubMed Web of Science ®Google Scholar
• Sarrell EM, Cohen HA, Kahan E. 2003. Naturopathic treatment for ear pain in children. Pediatrics. 111:574–579.
   PubMed Web of Science ®Google Scholar
• Skalkos D, Stavropoulos NE, Tsimaris I, Gioti E, Stalikas CD, Nseyo UO. 2005. The lipophilic extract of Hypericum perforatum exerts significant cytotoxic activity against T24 and NBT-II urinary bladder tumor cells. Planta Med. 71:1030–1035.
   PubMed Web of Science ®Google Scholar
• Stalikas CD, Konidari CN. 2001. Analysis of malondialdehyde in biological matrices by capillary gas chromatography with electron-capture detection and mass spectrometry. Anal Biochem. 290:108–115.
   PubMed Web of Science ®Google Scholar
• Stojanović G, Ðorđević A, Šmelcerović A. 2013. Do other Hypericum species have medical potential as St. John’s wort (Hypericum perforatum)? Curr Med Chem. 20:2273–2295.
   PubMed Web of Science ®Google Scholar
• Tawaha K, Gharaibeh M, El-Elimat T, Q Alali F. 2010. Determination of hypericin and hyperforin content in selected Jordanian Hypericum species. Ind Crops Prod. 32:241–245.
   Web of Science ®Google Scholar
• Unal EL, Mavi A, Kara AA, Cakir A, Şengül M, Yildirim A. 2008. Antimicrobial and antioxidant activities of some plants used as remedies in Turkish. Trad Med. 46:207–224.
   Google Scholar
• Veberic R, Colaric M, Stampar F. 2008. Phenolic acids and flavonoids of fig fruit (Ficus carica L.) in the northern Mediterranean region. Food Chem. 106:153–157.
   Web of Science ®Google Scholar
• Vinterhalter B, Ninkovic S, Cingel A, Vinterhalter D. 2006. Shoot and root culture of Hypericum perforatum L. transformed with Agrobacterium rhizogenes A4M70GUS. Biol Plantarum. 50:767–770.
   Web of Science ®Google Scholar
• Westh H, Zinn CS, Rosdahl VT. 2004. An international multicenter study of antimicrobial consumption and resistance in Staphylococcus aureus isolates from 15 hospitals in 14 countries. Microb Drug Resist. 10:169–176.
   PubMed Web of Science ®Google Scholar
• Zengin G, Sarikurkcu C, Aktumsek A, Ceylan R, Ceylan O. 2014. A comprehensive study on phytochemical characterization of Haplophyllum myrtifolium Boiss. endemic to Turkey and its inhibitory potential against key enzymes involved in Alzheimer skin diseases and type II diabetes. Ind Crop Prod. 53:244–251.
   Web of Science ®Google Scholar