969
Views
9
CrossRef citations to date
0
Altmetric
Research Article

Hepatoprotective effect of peony total glucosides and the underlying mechanisms in diabetic rats

, &
Pages 2178-2187 | Received 18 Mar 2017, Accepted 05 Oct 2017, Published online: 27 Oct 2017

References

  • Basseri S, Austin RC. 2012. Endoplasmic reticulum stress and lipid metabolism: mechanisms and therapeutic potential. Biochem Res Int. 84:1362.
  • Busaranogla M, Acbay O, Sonsuz A. 1999. A controlled trial of gemfibrozil in the treatment of patients with nonalcoholic steatohepatitis. J Hepatol. 31:384.
  • Chen Z, Li XP, Li ZJ, Xu L, Li XM. 2013. Reduced hepatotoxicity by total glucosides of paeony in combination treatment with leflunomide and methotrexate for patients with active rheumatoid arthritis. Int Immunopharmacol. 15:474–477.
  • Cnop M, Foufelle F, Velloso LA. 2012. Endoplasmic reticulum stress, obesity and diabetes. Trends Mol Med. 18:59–68.
  • de Cavanagh EM, Inserra F, Toblli J, Stella I, Fraga CG, Ferder L. 2001. Enalapril attenuates oxidative stress in diabetic rats. Hypertension. 38:1130–1136.
  • Evans JL, Goldfine ID, Maddux BA, Grodsky GM. 2002. Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr Rev. 23:599–622.
  • Farrell GC, Larter CZ. 2006. Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology. 43:S99–S112.
  • Folch J, Lees M, Slone Sanley GH. 1957. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem. 226:497–509.
  • Foster LB, Dunn RT. 1973. Stable reagents for determination of serum triglycerides by a colorimetric Hantzsch condensation method. Clin Chem. 19:338–340.
  • Fu S, Watkins SM, Hotamisligil GS. 2012. The role of endoplasmic reticulum in hepatic lipid homeostasis and stress signaling. Cell Metab. 15:623–634.
  • He JX, Akao T, Tani T. 2002. Development of a simple HPLC method for determination of paeoniflorin-metabolizing activity of intestinal bacteria in rat feces. Chem Pharm Bull. 50:1233–1237.
  • Hotamisligil GS. 2010. Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell. 140:900–917.
  • Liu DF, Wei W, Song LH. 2006. Protective effect of paeoniflorin on immunological liver injury induced by bacillus calmette-guerin plus lipopolysaccharide: modulation of tumour necrosis factor-alpha and interleukin-6 MRNA. Clin Exp Pharmacol Physiol. 33:332–339.
  • Liu F, Xie M, Chen D, Li J, Ding W. 2013. Effect of VIVO(dipic-Cl)(H2O)2 on lipid metabolism disorders in the liver of STZ-induced diabetic rats. J Diabetes Res. 2013:956737.
  • Maritim AC, Sanders RA, Watkins JB. 2003. Diabetes, oxidative stress, and antioxidants: a review. J Biochem Mol Toxicol. 17:24–38.
  • Martindale JL, Holbrook NJ. 2002. Cellular response to oxidative stress: signaling for suicide and survival. J Cell Physiol. 192:1–15.
  • Martinović V, Grigorov I, Bogojević D. 2012. Activation level of JNK and Akt/ERK signaling pathways determinates extent of DNA damage in the liver of diabetic rats. Cell Physiol Biochem. 30:723–734.
  • Morrison WR, Simth LM. 1964. Preparations of fatty acid methyl esters and dimethyl acetals from lipids with boron fluoride methanol. J Lipid Res. 5:600–607.
  • Navarro-González JF, Mora-Fernández C. 2008. The role of inflammatory cytokines in diabetic nephropathy. J Am Soc Nephrol. 19:433–442.
  • Newsholme P, Haber EP, Hirabara SM, Rebelato EL, Procopio J, Morgan D, Oliveira-Emilio HC, Carpinelli AR, Curi R. 2007. Diabetes associated cell stress and dysfunction: role of mitochondrial and non-mitochondrial ROS production and activity. J Physiol (Lond). 583:9–24.
  • Ohno T, Horio F, Tanaka S, Terada M, Namikawa T. 2000. Fatty liver and hyperlipidemia in IDDM (insulin-dependent diabetes mellitus) of streptozotocin-treated shrews. Life Sci. 66:125–131.
  • Ozcan L, Tabas I. 2012. Role of endoplasmic reticulum stress in metabolic disease and other disorders. Annu Rev Med. 63:317–328.
  • Parekh AC, Jung RT. 1970. Cholesterol determination with ferric acetate-uranium acetate and sulphuric acid-ferrous sulphate reagents. Anal Chem. 42:1423–1427.
  • Qin Y, Tian YP. 2011. Protective effects of total glucosides of paeony and the underlying mechanisms in carbon tetrachloride-induced experimental liver injury. Arch Med Sci. 7:604–612.
  • Rutkowski DT, Wu J, Back SH. 2008. UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. Dev Cell. 15:829–840.
  • Su J, Zhang P, Zhang JJ, Qi XM, Wu YG, Shen JJ. 2010. Effects of total glucosides of paeony on oxidative stress in the kidney from diabetic rats. Phytomedicine. 17:254–260.
  • Toblli JE, Ferder L, Stella I. 2002. Enalapril prevents fatty liver in nephrotic rats. J Nephrol. 15:358–367.
  • Watt KR, Pal C, Martin T, Harris L, Astatkie T, Kryzskaya D, Kärjä V, Mustonen AM, Tammi R. 2014. Evidence of endoplasmic reticulum stress and liver inflammation in the American mink Neovison vison with benign hepatic steatosis. J Comp Physiol B. 184:913–927.
  • Wei Y, Wang D, Topczewski F. 2006. Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells. Am J Physiol Endocrinol Metab. 291:E275–E281.
  • Welsh JA, Karpen S, Vos MB. 2012. Increasing prevalence of nonalcoholic fatty liver disease among United States adolescents, 1988–1994 to 2007–2010. J Pediatr. 162:496–500.
  • West IC. 2000. Radicals and oxidative stress in diabetes. Diabet Med. 17:171–180.
  • Wu YG, Ren KJ, Liang C, Yuan L, Qi XM, Dong J, Shen JJ, Lin SY. 2009. Renoprotective effect of total glucosides of paeony (TGP) and its mechanism in experimental diabetes. J Pharmacol Sci. 109:78–87.
  • Wu YG, Xia LL, Lin H, Zhou D, Qian H, Lin ST. 2007. Prevention of early liver injury by breviscapine in streptozotocin-induced diabetic rats. Planta Med. 73:433–438.
  • Xu SY, Chen MZ, Wei W. 1992. Pharmacology effects of total glycosides of peony. In: Zhou JH, editor. Progress in pharmacology and clinics of Chinese materia medical research, vol. 1. Beijing: Science and Technology of China Press; p. 49–59 [in Chinese].
  • Zhang K, Kaufman RJ. 2008. From endoplasmic-reticulum stress to the inflammatory response. Nature. 454:455–462.
  • Zhao M, Zang BC, Cheng MJ, Ma Y, Yang Y, Yang N. 2013. Differential responses of hepatic endoplasmic reticulum stress and inflammation in diet-induced obese rats with high-fat diet rich in lard oil or soybean oil. PLoS One. 8:e78620.
  • Zhou Z, Lin J, Huo R, Huang W, Zhang J, Wang L, Sun Y, Shen BH, Li NL. 2012. Total glucosides of paeony attenuated functional maturation of dendritic cells via blocking TLR4/5 signaling in vivo. Int Immunopharmacol. 14:275–282.