Anti-inflammatory and anti-osteoarthritis effect of Mollugo pentaphylla extract

References

• Ahmed S, Rahman A, Hasnain A, Lalonde M, Goldberg VM, Haqqi TM. 2002. Green tea polyphenol epigallocatechin-3-gallate inhibits the IL-1 beta-induced activity and expression of cyclooxygenase-2 and nitric oxide synthase-2 in human chondrocytes. Free Radic Biol Med. 33:1097–1105.
   PubMed Web of Science ®Google Scholar
• Akhtar N, Miller MJ, Haqqi TM. 2011. Effect of a herbal-leucine mix on the IL-1-beta-induced cartilage degradation and inflammatory gene expression in human chondrocytes. BMC Complement Altern Med. 11:66–75.
   PubMed Web of Science ®Google Scholar
• Barnes EV, Edwards NL. 2005. Treatment of osteoarthritis. South Med J. 98:205–209.
   PubMed Web of Science ®Google Scholar
• Bhatia D, Bejarano T, Novo M. 2013. Current interventions in the management of knee osteoarthritis. J Pharm Bioallied Sci. 5:30–38.
   PubMedGoogle Scholar
• Cameron M, Chrubasik S. 2013. Topical herbal therapies for treating osteoarthritis. Cochrane Database Syst Rev. (5):CD010538.
   Web of Science ®Google Scholar
• Castaneda S, Roman-Blas JA, Largo R, Herrero-Beaumont G. 2012. Subchondral bone as a key target for osteoarthritis treatment. Biochem Pharmacol. 83:315–323.
   PubMed Web of Science ®Google Scholar
• Chabane N, Zayed N, Afif H, Mfuna-Endam L, Benderdour M, Boileau C, Martel-Pelletier J, Pelletier JP, Duval N, Fahmi H. 2008. Histone deacetylase inhibitors suppress interleukin-1-beta-induced nitric oxide and prostaglandin E2 production in human chondrocytes. Osteoarthritis Cartilage. 16:1267–1274.
   PubMed Web of Science ®Google Scholar
• Chevalier X, Mugnier B, Bouvenot G. 2006. Targeted anti-cytokine therapies for osteoarthritis. Bull Acad Natl Med. 190:1411–1420.
   PubMed Web of Science ®Google Scholar
• Chun KS, Cha HH, Shin JW, Na HK, Park KK, Chung WY, Surh YJ. 2004. Nitric oxide induces expression of cyclooxygenase-2 in mouse skin through activation of NF-kappaB. Carcinogenesis. 25:445–454.
   PubMed Web of Science ®Google Scholar
• Combe R, Bramwell S, Field MJ. 2004. The monosodium iodoacetate model of osteoarthritis: a model of chronic nociceptive pain in rats? Neurosci Lett. 370:236–240.
   PubMed Web of Science ®Google Scholar
• Crofford LJ. 2013. Use of NSAIDs in treating patients with arthritis. Arthritis Res Ther. 15(3):S2.
   PubMed Web of Science ®Google Scholar
• de Lange-Brokaar BJ, Ioan-Facsinay A, van Osch GJ, Zuurmond AM, Schoones J, Toes RE, Huizinga TW, Kloppenburg M. 2012. Synovial inflammation, immune cells and their cytokines in osteoarthritis: a review. Osteoarthritis Cartilage. 20:1484–1499.
   PubMed Web of Science ®Google Scholar
• Dhippayom T, Kongkaew C, Chaiyakunapruk N, Dilokthornsakul P, Sruamsiri R, Saokaew S, Chuthaputti A. 2015. Clinical effects of Thai herbal compress: a systematic review and meta-analysis. Evid Based Complement Alternat Med. 2015:942378.
   PubMed Web of Science ®Google Scholar
• Fernandes JC, Martel-Pelletier J, Pelletier JP. 2002. The role of cytokines in osteoarthritis pathophysiology. Biorheology. 39:237–246.
   PubMed Web of Science ®Google Scholar
• Glyn-Jones S, Palmer AJ, Agricola R, Price AJ, Vincent TL, Weinans H, Carr AJ. 2015. Osteoarthritis. Lancet. 386:376–387.
   PubMed Web of Science ®Google Scholar
• Gong D, Geng C, Jiang L, Wang L, Yoshimura H, Zhong L. 2012. Mechanisms of olive leaf extract-ameliorated rat arthritis caused by kaolin and carrageenan. Phytother Res. 26:397–402.
   PubMed Web of Science ®Google Scholar
• Guerne PA, Carson DA, Lotz M. 1990. IL-6 production by human articular chondrocytes. Modulation of its synthesis by cytokines, growth factors, and hormones in vitro. J Immunol. 144:499–505.
   PubMed Web of Science ®Google Scholar
• Kapoor M, Martel-Pelletier J, Lajeunesse D, Pelletier JP, Fahmi H. 2011. Role of proinflammatory cytokines in the pathophysiology of osteoarthritis. Nat Rev Rheumatol. 7:33–42.
   PubMed Web of Science ®Google Scholar
• Kim SH, Choi HJ, Yang WK, Lee JE, Cho JH, Park IJ, Park S, Park BK, Jin M. 2017. Suppressive effect of the n-hexane extract of Litsea japonica fruit flesh on monosodium-iodoacetate-induced osteoarthritis in rats. Evid Based Complement Alternat Med. 2017:1791403.
   PubMed Web of Science ®Google Scholar
• Kim SS, Kim JY, Lee NH, Hyun CG. 2008. Antibacterial and anti-inflammatory effects of Jeju medicinal plants against acne-inducing bacteria. J Gen Appl Microbiol. 54:101–106.
   PubMed Web of Science ®Google Scholar
• Krasnokutsky S, Attur M, Palmer G, Samuels J, Abramson SB. 2008. Current concepts in the pathogenesis of osteoarthritis. Osteoarthritis Cartilage. 16: S1–S3.
   PubMed Web of Science ®Google Scholar
• Largo R, Alvarez-Soria MA, Dı́ez-Ortego I, Calvo E, Sánchez-Pernaute O, Egido J, Herrero-Beaumont G. 2003. Glucosamine inhibits IL-1-beta-induced NFkappaB activation in human osteoarthritic chondrocytes. Osteoarthritis Cartilage. 11:290–298.
   PubMed Web of Science ®Google Scholar
• Le Graverand-Gastineau MP. 2010. Disease modifying osteoarthritis drugs: facing development challenges and choosing molecular targets. Curr Drug Targets. 11:528–535.
   PubMed Web of Science ®Google Scholar
• Lechner M, Lirk P, Rieder J. 2005. Inducible nitric oxide synthase (iNOS) in tumor biology: the two sides of the same coin. Semin Cancer Biol. 15:277–289.
   PubMed Web of Science ®Google Scholar
• Lee YM, Shon EJ, Kim OS, Kim DS. 2017. Effects of Mollugo pentaphylla extract on monosodium urate crystal-induced gouty arthritis in mice. BMC Complement Altern Med. 17:447–554.
   PubMed Web of Science ®Google Scholar
• Lin CC, Ng LT, Yang JJ, Hsu YF. 2002. Anti-inflammatory and hepatoprotective activity of peh-hue-juwa-chi-cao in male rats. Am J Chin Med. 30:225–234.
   PubMed Web of Science ®Google Scholar
• Maiti UK, Mishra PK, Roy SK, Nandy S. 2012. Assessment of antiulcer activity of Mollugo pentaphylla Linn. in some experimental animal models. Int J Pharm Pharmaceut Sci. 4:488–496.
   Google Scholar
• Massicotte F, Lajeunesse D, Benderdour M, Pelletier JP, Hilal G, Duval N, Martel-Pelletier J. 2002. Can altered production of interleukin-1beta, interleukin-6, transforming growth factor-beta and prostaglandin E2 by isolated human subchondral osteoblasts identify two subgroups of osteoarthritic patients. Osteoarthritis Cartilage. 10:491–500.
   PubMed Web of Science ®Google Scholar
• McDougall JJ, Watkins L, Li Z. 2006. Vasoactive intestinal peptide (VIP) is a modulator of joint pain in a rat model of osteoarthritis. Pain. 123:98–105.
   PubMed Web of Science ®Google Scholar
• Meszaros EC, Dahoud W, Mesiano S, Malemud CJ. 2015. Blockade of recombinant human IL-6 by tocilizumab suppresses matrix metalloproteinase-9 production in the C28/I2 immortalized human chondrocyte cell line. Integr Mol Med. 2:304–310.
   PubMedGoogle Scholar
• Musumeci G, Carnazza ML, Leonardi R, Loreto C. 2012. Expression of β-defensin-4 in ‘an in vivo and ex vivo model' of human osteoarthritic knee meniscus. Knee Surg Sports Traumatol Arthrosc. 20:216–222.
   PubMed Web of Science ®Google Scholar
• Parente L. 2001. Pros and cons of selective inhibition of cyclooxygenase-2 versus dual lipoxygenase/cyclooxygenase inhibition: is two better than one? J Rheumatol. 28:2375–2382.
   PubMed Web of Science ®Google Scholar
• Philp AM, Davis ET, Jones SW. 2017. Developing anti-inflammatory therapeutics for patients with osteoarthritis. Rheumatology (Oxford). 56:869–881.
   PubMed Web of Science ®Google Scholar
• Pitcher T, Sousa-Valente J, Malcangio M. 2016. The monoiodoacetate model of osteoarthritis pain in the mouse. J Vis Exp. 16:e53746.
   Google Scholar
• Rahmati M, Mobasheri A, Mozafari M. 2016. Inflammatory mediators in osteoarthritis: a critical review of the state-of-the-art, current prospects, and future challenges. Bone. 85:81–90.
   PubMed Web of Science ®Google Scholar
• Sahu SK, Das D, Tripathy NK, Kumar HKS, Banerjee M. 2011. Anti-inflammatory, analgesic and antipyretic effects of Mollugo pentaphylla L. Rasayan J Chem. 4:533–538.
   Google Scholar
• Sellam J, Berenbaum F. 2010. The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis. Nat Rev Rheumatol. 6:625–635.
   PubMed Web of Science ®Google Scholar
• Sokolove J, Lepus CM. 2013. Role of inflammation in the pathogenesis of osteoarthritis: latest findings and interpretations. Ther Adv Musculoskelet Dis. 5:77–94.
   PubMedGoogle Scholar
• Thalhamer T, McGrath MA, Harnett MM. 2008. MAPKs and their relevance to arthritis and inflammation. Rheumatology (Oxford). 47:409–414.
   PubMed Web of Science ®Google Scholar
• Wojdasiewicz P, Poniatowski LA, Szukiewicz D. 2014. The role of inflammatory and anti-inflammatory cytokines in the pathogenesis of osteoarthritis. Mediators Inflamm. 2014:561459.
   PubMed Web of Science ®Google Scholar
• Zeng GQ, Chen AB, Li W, Song JH, Gao CY. 2015. High MMP-1, MMP-2, and MMP-9 protein levels in osteoarthritis. Genet Mol Res. 14:14811–14822.
   PubMed Web of Science ®Google Scholar
• Zhou J, Guirong X, Xinjian Y. 2011. Encyclopedia of Traditional Chinese Medicines. Berlin, Heidelberg.
   Google Scholar