Chronic unpredictable mild stress induced depression-like behaviours and glutamate-glutamine cycling dysfunctions in both blood and brain of mice

References

• Abbott NJ, Patabendige AAK, Dolman DEM, Yusof SR, Begley DJ. 2010. Structure and function of the blood-brain barrier. Neurobiol Dis. 37:13–25.
   PubMed Web of Science ®Google Scholar
• Abdallah CG, Sanacora G, Duman RS, Krystal JH. 2015. Ketamine and rapid-acting antidepressants: a window into a new neurobiology for mood disorder therapeutics. Ann Rev Med. 66:509–523.
   PubMed Web of Science ®Google Scholar
• Auer DP, Putz B, Kraft E, Lipinski B, Schill J, Holsboer F. 2000. Reduced glutamate in the anterior cingulate cortex in depression: an in vivo proton magnetic resonance spectroscopy study. Biol Psychiatry. 47:305–313.
   PubMed Web of Science ®Google Scholar
• Bradley KA, Alonso CM, Mehra LM, Xu J, Gabbay V. 2018. Elevated striatal γ-aminobutyric acid in youth with major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry. 86:203–210.
   PubMed Web of Science ®Google Scholar
• Brosnan JT. 2003. Interorgan amino acid transport and its regulation. J Nutr. 133:2068S–2072S.
   PubMed Web of Science ®Google Scholar
• Chandley MJ, Szebeni A, Szebeni K, Crawford JD, Stockmeier CA, Turecki G, Kostrzewa RM, Ordway GA. 2014. Elevated gene expression of glutamate receptors in noradrenergic neurons from the locus coeruleus in major depression. Int J Neuropsychopharmacol. 17:1569–1578.
   PubMed Web of Science ®Google Scholar
• Cocchi R. 1976. Antidepressive properties of l-glutamine. Preliminary report. Acta Psychiatrica Belgica Belg. 76:658–666.
   PubMedGoogle Scholar
• Daneman R, Prat A. 2015. The blood-brain barrier. Cold Spring Harb Perspect Biol. 7:a020412.
   PubMed Web of Science ®Google Scholar
• Godlewska BR, Near J, Cowen PJ. 2015. Neurochemistry of major depression: a study using magnetic resonance spectroscopy. Psychopharmacology. 232:501–507.
   PubMed Web of Science ®Google Scholar
• Hashimoto K, Bruno D, Nierenberg J, Marmar CR, Zetterberg H, Blennow K, Pomara N. 2016. Abnormality in glutamine-glutamate cycle in the cerebrospinal fluid of cognitively intact elderly individuals with major depressive disorder: a 3-year follow-up study. Transl Psychiatry. 6:e744–e749.
   PubMed Web of Science ®Google Scholar
• Hashimoto K, Sawa A, Iyo M. 2007. Increased levels of glutamate in brains from patients with mood disorders. Biol Psychiatry. 62:1310–1316.
   PubMed Web of Science ®Google Scholar
• Hasler G, van der Veen JW, Tumonis T, Meyers N, Shen J, Drevets WC. 2007. Reduced prefrontal glutamate/glutamine and gamma-aminobutyric acid levels in major depression determined using proton magnetic resonance spectroscopy. Arch Gen Psychiatry. 64:193–200.
   PubMed Web of Science ®Google Scholar
• Hawkins RA. 2009. The blood-brain barrier and glutamate. Am J Clin Nutr. 90:867S–874S.
   PubMed Web of Science ®Google Scholar
• Hawkins RA, Viña JR. 2016. How glutamate is managed by the blood-brain barrier. Biology. 5:37–43.
   Google Scholar
• Huang P, Dong Z, Huang W, Zhou C, Zhong W, Hu P, Wen G, Sun X, Hua H, Cao H, et al. 2017. Voluntary wheel running ameliorates depression-like behaviors and brain blood oxygen level-dependent signals in chronic unpredictable mild stress mice. Behav Brain Res. 330:17–24.
   PubMed Web of Science ®Google Scholar
• Küçükibrahimoğlu E, Saygin MZ, Calişkan M, Kaplan OK, Unsal C, Gören MZ. 2009. The change in plasma GABA, glutamine and glutamate levels in fluoxetine- or S-citalopram-treated female patients with major depression. Eur J Clin Pharmacol. 65:571–577.
   PubMed Web of Science ®Google Scholar
• Li C, Li M, Yu H, Shen X, Wang J, Sun X, Wang Q, Wang C. 2017. Neuropeptide VGF C-terminal peptide TLQP-62 alleviates lipopolysaccharide-induced memory deficits and anxiety-like and depression-like behaviors in mice: the role of BDNF/TrkB signaling. ACS Chem Neurosci. 8:2005–2018.
   PubMed Web of Science ®Google Scholar
• Lin P, Wang C, Xu B, Gao S, Guo J, Zhao X, Huang H, Zhang J, Chen X, Wang Q, et al. 2014. The VGF-derived peptide TLQP-62 produces antidepressant-like effects in mice via the BDNF/TrkB/CREB signaling pathway. Pharmacol Biochem Behav. 120:140–148.
   PubMed Web of Science ®Google Scholar
• Machado-Vieira R, Salvadore G, Luckenbaugh DA, Manji HK, Zarate CA. Jr. 2008. Rapid onset of antidepressant action: a new paradigm in the research and treatment of major depressive disorder. J Clin Psychiatry. 69:946–958.
   PubMed Web of Science ®Google Scholar
• Mohler H. 2012. The GABA system in anxiety and depression and its therapeutic potential. Neuropharmacology. 62:42–53.
   PubMed Web of Science ®Google Scholar
• Moreau JL. 1997. Validation of an animal model of anhedonia, a major symptom of depression. Encephale. 23:280–289.
   PubMed Web of Science ®Google Scholar
• Murrough JW, Abdallah CG, Mathew SJ. 2017. Targeting glutamate signalling in depression: progress and prospects. Nat Rev Drug Discov. 16:472–486.
   PubMed Web of Science ®Google Scholar
• Penteado JC, Rigobello-Masini M, Liria CW, Miranda MT, Masini JC. 2009. Fluorimetric determination of intra- and extracellular free amino acids in the microalgae Tetraselmis gracilis (Prasinophyceae) using monolithic column in reversed phase mode. J Sep Sci. 32:2827–2834.
   PubMed Web of Science ®Google Scholar
• Serchov T, Calker DV, Biber K. 2016. Sucrose preference test to measure anhedonic behaviour in mice. BioProtocol. 6:e1958.
   Google Scholar
• Sharma HR, Thakur MK. 2015. Correlation of ERα/ERβ expression with dendritic and behavioural changes in CUMS mice. Physiol Behav. 145:71–83.
   PubMed Web of Science ®Google Scholar
• Steru L, Chermat R, Thierry B, Simon P. 1985. The tail suspension test: a new method for screening antidepressants in mice. Psychopharmacology. 85:367–370.
   PubMed Web of Science ®Google Scholar
• World Health Organization. 2017. Depression and other common mental disorders: global health estimates. Geneva, Switzerland: CC BY-NC-SA 3.0 IGO.
   Google Scholar