Silk peptide treatment potentiates natural killer cell activity in vitro and induces natural killer cell maturation and activation in mouse splenocytes

References

• Ahmad R, Kamra A, Hasnain SE. 2004. Fibroin silk proteins from the nonmulberry silkworm Philosamia ricini are biochemically and immunochemically distinct from those of the mulberry silkworm Bombyx mori. DNA Cell Biol. 23:149–154.
   PubMed Web of Science ®Google Scholar
• Aktas E, Kucuksezer UC, Bilgic S, Erten G, Deniz G. 2009. Relationship between CD107a expression and cytotoxic activity. Cell Immunol. 254:149–154.
   PubMed Web of Science ®Google Scholar
• Aubry JP, Blaecke A, Lecoanet-Henchoz S, Jeannin P, Herbault N, Caron G, Moine V, Bonnefoy JY. 1999. Annexin V used for measuring apoptosis in the early events of cellular cytotoxicity. Cytometry. 37:197–204.
   PubMedGoogle Scholar
• Betts MR, Brenchley JM, Price DA, De Rosa SC, Douek DC, Roederer M, Koup RA. 2003. Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation. J Immunol Methods. 281:65–78.
   PubMed Web of Science ®Google Scholar
• Chang H, Jin BR, Jang YS, Kim WS, Kim PH. 2012. Lactoferrin stimulates mouse macrophage to express BAFF via Smad3 pathway. Immune Network. 12:84–88.
   PubMedGoogle Scholar
• Chiossone L, Chaix J, Fuseri N, Roth C, Vivier E, Walzer T. 2009. Maturation of mouse NK cells is a 4-stage developmental program. Blood. 113:5488–5496.
   PubMed Web of Science ®Google Scholar
• Cui X, Wen J, Zhao X, Chen X, Shao Z, Jiang JJ. 2013. A pilot study of macrophage responses to silk fibroin particles. J Biomed Materials Res A. 101:1511–1517.
   PubMed Web of Science ®Google Scholar
• Egusa S, Otani H. 2009. Soybean protein fraction digested with neutral protease preparation, “Peptidase R, produced by Rhizopus oryzae, stimulates innate cellular immune system in mouse”. Int Immunopharmacol. 9:931–936.
   PubMed Web of Science ®Google Scholar
• Eyileten C, Majchrzak K, Pilch Z, Tonecka K, Mucha J, Taciak B, Ulewicz K, Witt K, Boffi A, Krol M, et al. 2016. Immune cells in cancer therapy and drug delivery. Mediators Inflamm. 2016:5230219.
   PubMed Web of Science ®Google Scholar
• Glas R, Franksson L, Une C, Eloranta ML, Ohlén C, Örn A, Kärre K. 2000. Recruitment and activation of natural killer (NK) cells in vivo determined by the target cell phenotype. An adaptive component of NK cell-mediated responses. J Exp Med. 191:129–138.
   PubMed Web of Science ®Google Scholar
• Gotoh K, Izumi H, Kanamoto T, Tamada Y, Nakashima H. 2000. Sulfated fibroin, a novel sulfated peptide derived from silk, inhibits human immunodeficiency virus replication in vitro. Biosci Biotechnol Biochem. 64:1664–1670.
   PubMed Web of Science ®Google Scholar
• Guadagni M, Biolo G. 2009. Effects of inflammation and/or inactivity on the need for dietary protein. Curr Opin Clin Nutr Metabolic Care. 12:617–622.
   PubMed Web of Science ®Google Scholar
• Guedan S, Ruella M, June CH. 2019. Emerging cellular therapies for cancer. Ann Rev Immunol. 37:145–171.
   PubMed Web of Science ®Google Scholar
• Hayakawa Y, Huntington ND, Nutt SL, Smyth MJ. 2006. Functional subsets of mouse natural killer cells. Immunol Rev. 214:47–55.
   PubMed Web of Science ®Google Scholar
• Igarashi K, Yoshioka K, Mizutani K, Miyakoshi M, Murakami T, Akizawa T. 2006. Blood pressure-depressing activity of a peptide derived from silkworm fibroin in spontaneously hypertensive rats. Biosci Biotechnol Biochem. 70:517–520.
   PubMed Web of Science ®Google Scholar
• Ikegawa Y, Sato S, Lim G, Hur W, Tanaka K, Komori M, Takenaka S, Taira T. 2012. Amelioration of the progression of an atopic dermatitis-like skin lesion by silk peptide and identification of functional peptides. Biosci Biotechnol Biochem. 76:473–477.
   PubMed Web of Science ®Google Scholar
• Jang SH, Oh MS, Baek HI, Ha KC, Lee JY, Jang YS. 2018. Oral administration of silk peptide enhances the maturation and cytolytic activity of natural killer cells. Immune Network. 18:e37.
   PubMed Web of Science ®Google Scholar
• Jung EY, Lee HS, Lee HJ, Kim JM, Lee KW, Suh HJ. 2010. Feeding silk protein hydrolysates to C57BL/KsJ-db/db mice improves blood glucose and lipid profiles. Nutr Res. 30:783–790.
   PubMed Web of Science ®Google Scholar
• Kaewkorn W, Limpeanchob N, Tiyaboonchai W, Pongcharoen S, Sutheerawattananonda M. 2012. Effects of silk sericin on the proliferation and apoptosis of colon cancer cells. Biol Res. 45:45–50.
   PubMed Web of Science ®Google Scholar
• Kärre K, Ljunggren HG, Piontek G, Kiessling R. 1986. Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defense strategy. Nature. 319:675–678.
   PubMed Web of Science ®Google Scholar
• Khan MM. 2008. Role of cytokines. In: M.M. Khan, editor. Immunopharmacology, Boston, MA, USA: Springer.
   Google Scholar
• Kim TK, Park D, Yeon S, Lee SH, Choi YJ, Bae DK, Yang YH, Yang G, Joo SS, Lim WT, et al. 2011. Tyrosine-fortified silk amino acids improve physical function of Parkinson's disease rats. Food Sci Biotechnol. 20:79–84.
   Web of Science ®Google Scholar
• Kuhara T, Yamauchi K, Tamura Y, Okamura H. 2006. Oral administration of lactoferrin increases NK cell activity in mice via increased production of IL-18 and type I IFN in the small intestine. J Interferon Cytokine Res. 26:489–499.
   PubMed Web of Science ®Google Scholar
• Lee SH, Park D, Yang G, Bae DK, Yang YH, Kim TK, Kim D, Kyung J, Yeon S, Koo KC, et al. 2012. Silk and silkworm pupa peptides suppress adipogenesis in preadipocytes and fat accumulation in rats fed a high-fat diet. Eur J Nutr. 51:1011–1019.
   PubMed Web of Science ®Google Scholar
• Li P, Yin YL, Li D, Kim SW, Wu G. 2007. Amino acids and immune function. Br J Nutr. 98:237–252.
   PubMed Web of Science ®Google Scholar
• Moon JH, Pyo KH, Jung BK, Chun HS, Chai JY, Shin EH. 2011. Resistance to Toxoplasma gondii infection in mice treated with silk protein by enhanced immune responses. Korean J Parasitol. 49:303–308.
   PubMed Web of Science ®Google Scholar
• Nagai N, Murao T, Ito Y, Okamoto N, Sasaki M. 2009. Enhancing effects of sericin on corneal wound healing in Otsuka Long-Evans Tokushima fatty rats as a model of human type 2 diabetes. Biol Pharm Bull Pharm. 32:1594–1599.
   PubMed Web of Science ®Google Scholar
• Pejin B, Glumac M. 2018. New cytotoxic natural products from the mangrove biome: covering the period 2007-2015. Natl Prod Res. 15:1–5.
   Google Scholar
• Pejin B, Mojovic M, Savic AG. 2014. Novel and highly potent antitumor natural products from cnidarians of marine origin. Nat Prod Res. 28:2237–2244.
   PubMed Web of Science ®Google Scholar
• Seo CW, Um IC, Rico CW, Kang MY. 2011. Antihyperlipidemic and body fat-lowering effects of silk proteins with different fibroin/sericin compositions in mice fed with high fat diet. J Agric Food Chem. 59:4192–4197.
   PubMed Web of Science ®Google Scholar
• Singh TM, Kadowaki MH, Glagov S, Zarins CK. 1990. Role of fibrinopeptide B in early atherosclerotic lesion formation. Am J Surg. 160:156–159.
   PubMed Web of Science ®Google Scholar
• Smyth MJ, Crowe NY, Hayakawa Y, Takeda K, Yagita H, Godfrey DI. 2002. NKT cells - conductors of tumor immunity? Curr Opin Immunol. 14:165–171.
   PubMed Web of Science ®Google Scholar
• Teramoto H, Kameda T, Tamada Y. 2008. Preparation of gel film from Bombyx mori silk sericin and its characterization as a wound dressing. Biosci Biotechnol Biochem. 72:3189–3196.
   PubMed Web of Science ®Google Scholar
• Topham NJ, Hewitt EW. 2009. Natural killer cell cytotoxicity: how do they pull the trigger?. Immunology. 128:7–15.
   PubMed Web of Science ®Google Scholar
• Uff CR, Scott AD, Pockley AG, Phillips RK. 1995. Influence of soluble suture factors on in vitro macrophage function. Biomaterials. 16:355–360.
   PubMed Web of Science ®Google Scholar
• Vivier E, Tomasello E, Baratin M, Walzer T, Ugolini S. 2008. Functions of natural killer cells. Nat Immunol. 9:503–510.
   PubMed Web of Science ®Google Scholar
• Walzer T, Dalod M, Robbins SH, Zitvogel L, Vivier E. 2005. Natural-killer cells and dendritic cells: “l'union fait la force”. Blood. 106:2252–2258.
   PubMed Web of Science ®Google Scholar
• Wang MS, Du YB, Huang HM, Zhu ZL, Du SS, Chen SY, Zhao HP, Yan Z. 2019. Silk fibroin peptide suppresses proliferation and induces apoptosis and cell cycle arrest in human lung cancer cells. Acta Pharmacologica Sinica. 40:522–529.
   PubMed Web of Science ®Google Scholar
• Watzl C, Long EO. 2010. Signal transduction during activation and inhibition of natural killer cells. Curr Protoc Immunol. 90:9B.1–11.
   Google Scholar
• Zhaorigetu S, Sasaki M, Watanabe H, Kato N. 2001. Supplemental silk protein, sericin, suppresses colon tumorigenesis in 1,2-dimethylhydrazine-treated mice by reducing oxidative stress and cell proliferation. Biosci Biotechnol Biochem. 65:2181–2186.
   PubMed Web of Science ®Google Scholar