Pharmacokinetic interaction between peimine and paeoniflorin in rats and its potential mechanism

References

• Aszalos A. 2007. Drug–drug interactions affected by the transporter protein, P-glycoprotein (ABCB1, MDR1). I. Preclinical aspects. Drug Discov Today. 12(19–20):833–837.
   PubMed Web of Science ®Google Scholar
• Balayssac D, Authier N, Cayre A, Coudore F. 2005. Does inhibition of P-glycoprotein lead to drug–drug interactions? Toxicol Lett. 156(3):319–329.
   PubMed Web of Science ®Google Scholar
• Chen D, Zhao J, Cong W. 2018. Chinese herbal medicines facilitate the control of chemotherapy-induced side effects in colorectal cancer: progress and perspective. Front Pharmacol. 9:1442–1452.
   PubMed Web of Science ®Google Scholar
• Chen F, Lu HT, Jiang Y. 2004. Purification of paeoniflorin from Paeonia lactiflora Pall. by high-speed counter-current chromatography. J Chromatogr A. 1040(2):205–208.
   PubMed Web of Science ®Google Scholar
• Chen L, Lu X, Liang X, Hong D, Guan Z, Guan Y, Zhu W. 2016. Mechanistic studies of the transport of peimine in the Caco-2 cell model. Acta Pharm Sin B. 6(2):125–131.
   PubMed Web of Science ®Google Scholar
• Chen T, Fu LX, Zhang LW, Yin B, Zhou PM, Cao N, Lu YH. 2016. Paeoniflorin suppresses inflammatory response in imiquimod-induced psoriasis-like mice and peripheral blood mononuclear cells (PBMCs) from psoriasis patients. Can J Physiol Pharmacol. 94(8):888–894.
   PubMed Web of Science ®Google Scholar
• Choi YH, Chin YW, Kim YG. 2011. Herb–drug interactions: focus on metabolic enzymes and transporters. Arch Pharm Res. 34(11):1843–1863.
   PubMed Web of Science ®Google Scholar
• Geffrey AL, Pollack SF, Bruno PL, Thiele EA. 2015. Drug–drug interaction between clobazam and cannabidiol in children with refractory epilepsy. Epilepsia. 56(8):1246–1251.
   PubMed Web of Science ®Google Scholar
• Hamberg P, Woo MM, Chen LC, Verweij J, Porro MG, Zhao L, Li W, van der Biessen D, Sharma S, Hengelage T, et al. 2011. Effect of ketoconazole-mediated CYP3A4 inhibition on clinical pharmacokinetics of panobinostat (LBH589), an orally active histone deacetylase inhibitor. Cancer Chemother Pharmacol. 68(3):805–813.
   PubMed Web of Science ®Google Scholar
• Ji HY, Liu KH, Kong TY, Jeong HU, Choi SZ, Son M, Cho YY, Lee HS. 2013. Evaluation of DA-9801, a new herbal drug for diabetic neuropathy, on metabolism-mediated interaction. Arch Pharm Res. 36(1):1–5.
   PubMed Web of Science ®Google Scholar
• Jia Z, He J. 2016. Paeoniflorin ameliorates rheumatoid arthritis in rat models through oxidative stress, inflammation and cyclooxygenase 2. Exp Ther Med. 11(2):655–659.
   PubMed Web of Science ®Google Scholar
• Lamas A, Ruiz de Valbuena M, Maiz L. 2014. Cough in children. Arch Bronconeumol. 50(7):294–300.
   PubMed Web of Science ®Google Scholar
• Li H, Hung A, Li M, Yang AWH. 2019. Fritillariae thunbergii bulbus: traditional uses, phytochemistry, pharmacodynamics, pharmacokinetics and toxicity. Int J Mol Sci. 20(7):1667–1698.
   PubMed Web of Science ®Google Scholar
• Li M, Liu X, Wang Y, Ju X. 2020. In vitro effects of peimine on the activity of cytochrome P450 enzymes. Xenobiotica. 50(10):1202–1207.
   PubMed Web of Science ®Google Scholar
• Li SL, Chan SW, Li P, Lin G, Zhou GH, Ren YJ, Chiu FC. 1999. Pre-column derivatization and gas chromatographic determination of alkaloids in bulbs of Fritillaria. J Chromatogr A. 859(2):183–192.
   PubMed Web of Science ®Google Scholar
• Nishihara M, Yamasaki H, Czerniak R, Jenkins H. 2019. In vitro assessment of potential for CYP-inhibition-based drug–drug interaction between vonoprazan and clopidogrel. Eur J Drug Metab Pharmacokinet. 44(2):217–227.
   PubMed Web of Science ®Google Scholar
• Pae HO, Oh H, Choi BM, Oh GS, Paik SG, Jeong S, Hwang KM, Yun YG, Chung HT. 2002. Differentiation-inducing effects of verticinone, an isosteroidal alkaloid isolated from the bulbus of Fritillaria ussuriensis, on human promyelocytic leukemia HL-60 cells. Biol Pharm Bull. 25(11):1409–1411.
   PubMed Web of Science ®Google Scholar
• Park JH, Lee B, Kim HK, Kim EY, Kim JH, Min JH, Kim S, Sohn Y, Jung HS. 2017. Peimine inhibits the production of proinflammatory cytokines through regulation of the phosphorylation of NF-κB and MAPKs in HMC-1 cells. Pharmacogn Mag. 13(Suppl. 2):S359–S364.
   PubMedGoogle Scholar
• Sun H, Wang J, Lv J. 2019. Effects of glycyrrhizin on the pharmacokinetics of paeoniflorin in rats and its potential mechanism. Pharm Biol. 57(1):550–554.
   PubMed Web of Science ®Google Scholar
• Xin Q, Yuan R, Shi W, Zhu Z, Wang Y, Cong W. 2019. A review for the anti-inflammatory effects of paeoniflorin in inflammatory disorders. Life Sci. 237:116925.
   PubMed Web of Science ®Google Scholar
• Xu J, Zhao W, Pan L, Zhang A, Chen Q, Xu K, Lu H, Chen Y. 2016. Peimine, a main active ingredient of Fritillaria, exhibits anti-inflammatory and pain suppression properties at the cellular level. Fitoterapia. 111:1–6.
   PubMed Web of Science ®Google Scholar
• Yamamoto T, Furihata K, Hisaka A, Moritoyo T, Ogoe K, Kusayama S, Motohashi K, Mori A, Iwatsubo T, Suzuki H. 2017. Notable drug–drug interaction between etizolam and itraconazole in poor metabolizers of cytochrome P450 2C19. J Clin Pharmacol. 57(11):1491–1499.
   PubMed Web of Science ®Google Scholar
• Zhang J, Dou W, Zhang E, Sun A, Ding L, Wei X, Chou G, Mani S, Wang Z. 2014. Paeoniflorin abrogates DSS-induced colitis via a TLR4-dependent pathway. Am J Physiol Gastrointest Liver Physiol. 306(1):G27–G36.
   PubMed Web of Science ®Google Scholar
• Zhang L, Cui M, Chen S. 2020. Identification of the molecular mechanisms of peimine in the treatment of cough using computational target fishing. Molecules. 25(5):1105–1116.
   PubMed Web of Science ®Google Scholar
• Zhou H, Wu Q, Wei L, Peng S. 2018. Paeoniflorin inhibits PDGF-BB-induced human airway smooth muscle cell growth and migration. Mol Med Rep. 17(2):2660–2664.
   PubMed Web of Science ®Google Scholar