3,396
Views
23
CrossRef citations to date
0
Altmetric
Research Article

Identification of the protective effect of Polygonatum sibiricum polysaccharide on d-galactose-induced brain ageing in mice by the systematic characterization of a circular RNA-associated ceRNA network

, , , , , & show all
Pages 345-364 | Received 06 Oct 2020, Accepted 16 Feb 2021, Published online: 01 Apr 2021

References

  • Apple DM, Solano-Fonseca R, Kokovay E. 2017. Neurogenesis in the aging brain. Biochem Pharmacol. 141:77–85.
  • Bartel DP. 2004. MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell. 116(2):281–297.
  • Berwick DC, Harvey K. 2014. The regulation and deregulation of Wnt signaling by PARK genes in health and disease. J Mol Cell Biol. 6(1):3–12.
  • Bishop NA, Lu T, Yankner BA. 2010. Neural mechanisms of ageing and cognitive decline. Nature. 464(7288):529–535.
  • Brunso-Bechtold JK, Linville MC, Sonntag WE. 2000. Age-related synaptic changes in sensorimotor cortex of the Brown Norway X fischer 344 rat. Brain Res. 872(1-2):125–133.
  • Carbajosa G, Malki K, Lawless N, Wang H, Ryder JW, Wozniak E, Wood K, Mein CA, Dobson RJB, Collier DA, et al. 2018. Loss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain. Neurobiol Aging. 69:151–166.
  • Caricasole A, Copani A, Caraci F, Aronica E, Rozemuller AJ, Caruso A, Storto M, Gaviraghi G, Terstappen GC, Nicoletti F. 2004. Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is associated with neuronal degeneration in Alzheimer's brain. J Neurosci. 24(26):6021–6027.
  • Crux S, Herms J, Dorostkar MM. 2018. Tcf4 regulates dendritic spine density and morphology in the adult brain. PLoS One. 13(6):e0199359
  • Deak F, Sonntag WE. 2012. Aging, synaptic dysfunction, and insulin-like growth factor (IGF)−1. J Gerontol A Biol Sci Med Sci. 67(6):611–625.
  • Dickson DW, Crystal HA, Bevona C, Honer W, Vincent I, Davies P. 1995. Correlations of synaptic and pathological markers with cognition of the elderly. Neurobiol Aging. 16(3):285–298; discussion 98-304.
  • Eacker SM, Keuss MJ, Berezikov E, Dawson VL, Dawson TM. 2011. Neuronal activity regulates hippocampal miRNA expression. PLoS One. 6(10):e25068.
  • Esteller M. 2011. Non-coding RNAs in human disease. Nat Rev Genet. 12(12):861–874.
  • Feng Z, Zhang L, Wang S, Hong Q. 2020. Circular RNA circDLGAP4 exerts neuroprotective effects via modulating miR-134-5p/CREB pathway in Parkinson's disease. Biochem Biophys Res Commun. 522(2):388–394.
  • Hallows WC, Yu W, Smith BC, Devires MK, Ellinger JJ, Someya S, Shortreed MR, Prolla T, Markley JL, Smith LM, et al. 2011. Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction. Mol Cell. 41(2):139–149.
  • Inukai S, de Lencastre A, Turner M, Slack F. 2012. Novel microRNAs differentially expressed during aging in the mouse brain. PLoS One. 7(7):e40028.
  • Knupp D, Miura P. 2018. CircRNA accumulation: A new hallmark of aging? Mech Ageing Dev. 173:71–79.
  • Kumar S, Vijayan M, Bhatti JS, Reddy PH. 2017. MicroRNAs as peripheral biomarkers in aging and age-related diseases. Prog Mol Biol Transl Sci. 146:47–94.
  • Lee YI, Kim YG, Pyeon HJ, Ahn JC, Logan S, Orock A, Joo KM, Lőrincz A, Deák F. 2019. Dysregulation of the SNARE-binding protein Munc18-1 impairs BDNF secretion and synaptic neurotransmission: a novel interventional target to protect the aging brain. Geroscience. 41(2):109–123.
  • Li JJ, Zhu Q, Lu YP, Zhao P, Feng ZB, Qian ZM, Zhu L. 2015. Ligustilide prevents cognitive impairment and attenuates neurotoxicity in d-galactose induced aging mice brain. Brain Res. 1595:19–28.
  • Li YY, Deng HB, Wang R, Chen LL. 2005. The change of telomerase activity in aging mice tissue and the interference of Plyonatum sibiricum. J. Clin. Res. 22:894–895.
  • Libro R, Bramanti P, Mazzon E. 2016. The role of the Wnt canonical signaling in neurodegenerative diseases. Life Sci. 158:78–88.
  • Liu N, Dong Z, Zhu X, Xu H, Zhao Z. 2018. Characterization and protective effect of Polygonatum sibiricum polysaccharide against cyclophosphamide-induced immunosuppression in Balb/c mice. Int J Biol Macromol. 107(Pt A):796–802.
  • López-Otín C, Blasco M, Partridge L, Serrano M, Kroemer G. 2013. The hallmarks of aging. Cell. 153(6):1194–1217.
  • Mecocci P, Boccardi V, Cecchetti R, Bastiani P, Scamosci M, Ruggiero C, Baroni M. 2018. A long journey into aging, brain aging, and Alzheimer's disease following the oxidative stress tracks. JAD. 62(3):1319–1335.
  • Memczak S, Jens M, Elefsinioti A, Torti F, Krueger J, Rybak A, Maier L, Mackowiak SD, Gregersen LH, Munschauer M, et al. 2013. Circular RNAs are a large class of animal RNAs with regulatory potency. Nature. 495(7441):333–338.
  • Nam SM, Seo M, Seo JS, Rhim H, Nahm SS, Cho IH, Chang BJ, Kim HJ, Choi SH, Nah SY. 2019. Ascorbic acid mitigates d-galactose-induced brain aging by increasing hippocampal neurogenesis and improving memory function. Nutrients. 11(1):176.
  • Peters A, Sethares C, Luebke JI. 2008. Synapses are lost during aging in the primate prefrontal cortex. Neuroscience. 152(4):970–981.
  • Pourmemar E, Majdi A, Haramshahi M, Talebi M, Karimi P, Sadigh-Eteghad S. 2017. Intranasal cerebrolysin attenuates learning and memory impairments in d-galactose-induced senescence in mice. Exp Gerontol. 87(Pt A):16–22.
  • Qiu X, Brown K, Hirschey MD, Verdin E, Chen D. 2010. Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation. Cell Metab. 12(6):662–667.
  • Qu S, Yang X, Li X, Wang J, Gao Y, Shang R, Sun W, Dou K, Li H. 2015. Circular RNA: A new star of noncoding RNAs. Cancer Lett. 365(2):141–148.
  • Roser AE, Caldi Gomes L, Halder R, Jain G, Maass F, Tönges L, Tatenhorst L, Bähr M, Fischer A, Lingor P. 2018. miR-182-5p and miR-183-5p act as GDNF mimics in dopaminergic midbrain neurons. Mol Ther Nucleic Acids. 11:9–22.
  • Smith-Geater C, Hernandez SJ, Lim RG, Adam M, Wu J, Stocksdale JT, Wassie BT, Gold MP, Wang KQ, Miramontes R, et al. 2020. Aberrant development corrected in adult-onset huntington's disease iPSC-derived neuronal cultures via WNT signaling modulation. Stem Cell Reports. 14(3):406–419.
  • Soghomonian JJ, Sethares C, Peters A. 2010. Effects of age on axon terminals forming axosomatic and axodendritic inhibitory synapses in prefrontal cortex. Neuroscience. 168(1):74–81.
  • Szafranski K, Abraham KJ, Mekhail K. 2015. Non-coding RNA in neural function, disease, and aging. Front Genet. 6:1–16.
  • Tong S, Fei W, Emily S, Qiang T. 2005. SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes. J Biol Chem. 280(14):13560–13567.
  • VanGuilder HD, Farley JA, Yan H, Van Kirk CA, Mitschelen M, Sonntag WE, Freeman WM. 2011. Hippocampal dysregulation of synaptic plasticity-associated proteins with age-related cognitive decline. Neurobiol Dis. 43(1):201–212.
  • VanGuilder HD, Yan H, Farley JA, Sonntag WE, Freeman WM. 2010. Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome. J Neurochem. 113(6):1577–1588.
  • Wang Z, Xu P, Chen B, Zhang Z, Zhang C, Zhan Q, Huang S, Xia ZA, Peng W. 2018. Identifying circRNA-associated-ceRNA networks in the hippocampus of Aβ1-42-induced Alzheimer's disease-like rats using microarray analysis. Aging. 10(4):775–788.
  • Warnefors M, Liechti A, Halbert J, Valloton D, Kaessmann H. 2014. Conserved microRNA editing in mammalian evolution, development and disease. Genome Biol. 15(6):R83.
  • Xie Y, Niu M, Ji C, Huang TY, Zhang C, Tian Y, Shi Z, Wang C, Zhao Y, Luo H, et al. 2019. SNX8 enhances non-amyloidogenic APP trafficking and attenuates abeta accumulation and memory deficits in an AD mouse. Front Cell Neurosci. 13:1–11.
  • Yi YX, Wu SX, Ye MS, Zeng Y, Zhang P, Xie YQ. 2014. Effect of Aβ (1-42) injection on hippocampus cells in rats and protective role of polygona-polysaccharose for Alzheimer’s disease. J. Cent. South. Univ. 39:344–348.
  • Zhang H-M, Diaz V, Walsh ME, Zhang Y. 2017. Moderate lifelong overexpression of tuberous sclerosis complex 1 (TSC1) improves health and survival in mice. Sci Rep. 7(1):14.
  • Zhang Q, Li XK, Cui X, Zuo PP. 2005. d-Galactose injured neurogenesis in the hippocampus of adult mice. Neurol Res. 27(5):552–556.
  • Zhang Z, Li B, Xu P, Yang B. 2019. Integrated whole transcriptome profiling and bioinformatics analysis for revealing regulatory pathways associated with quercetin-induced apoptosis in HCT-116 cells. Front Pharmacol. 10:1–18.
  • Zhao X, Li J. 2015. Chemical constituents of the genus Polygonatum and their role in medicinal treatment. Nat Prod Comm. 10:683–688.
  • Zhao Y, Kiss T, DelFavero J, Li L, Li X, Zheng L, Wang J, Jiang C, Shi J, Ungvari Z, et al. 2020. CD82-TRPM7-Numb signaling mediates age-related cognitive impairment. Geroscience. 42(2):595–611.
  • Zheng S. 2020. Protective effect of Polygonatum sibiricum polysaccharide on d-galactose-induced aging rats model. Sci Rep. 10(1):13.