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Research Article

Effect of dihydromyricetin on hepatic encephalopathy associated with acute hepatic failure in mice

, , , , & ORCID Icon
Pages 555-562 | Received 25 Sep 2020, Accepted 11 Apr 2021, Published online: 13 May 2021

References

  • Avraham Y, Grigoriadis N, Poutahidis T, Vorobiev L, Magen I, Ilan Y, Mechoulam R, Berry E. 2011. Cannabidiol improves brain and liver function in a fulminant hepatic failure-induced model of hepatic encephalopathy in mice. Br J Pharmacol. 162(7):1650–1658.
  • Cauli O, Rodrigo R, Piedrafita B, Boix J, Felipo V. 2007. Inflammation and hepatic encephalopathy: ibuprofen restores learning ability in rats with portacaval shunts. Hepatology. 46(2):514–519.
  • Dadsetan S, Balzano T, Forteza J, Cabrera-Pastor A, Taoro-Gonzalez L, Hernandez-Rabaza V, Gil-Perotin S, Cubas-Nunez L, Garcia-Verdugo JM, Agusti A, et al. 2016. Reducing peripheral inflammation with infliximab reduces neuroinflammation and improves cognition in rats with hepatic encephalopathy. Front Mol Neurosci. 9:106.
  • Ding S, Zhuge W, Hu J, Yang J, Wang X, Wen F, Wang C, Zhuge Q. 2018. Baicalin reverses the impairment of synaptogenesis induced by dopamine burden via the stimulation of GABAAR-TrkB interaction in minimal hepatic encephalopathy. Psychopharmacology. 235(4):1163–1178.
  • Fromowitz FB, Viola MV, Chao S, Oravez S, Mishriki Y, Finkel G, Grimson R, Lundy J. 1987. ras p21 expression in the progression of breast cancer. Hum Pathol. 18(12):1268–1275.
  • Gorg B, Karababa A, Shafigullina A, Bidmon HJ, Haussinger D. 2015. Ammonia-induced senescence in cultured rat astrocytes and in human cerebral cortex in hepatic encephalopathy. Glia. 63(1):37–50.
  • Hadjihambi A, Arias N, Sheikh M, Jalan R. 2018. Hepatic encephalopathy: a critical current review. Hepatol Int. 12(S1):135–147.
  • Hernandez-Rabaza V, Cabrera-Pastor A, Taoro-Gonzalez L, Malaguarnera M, Agusti A, Llansola M, Felipo V. 2016. Hyperammonemia induces glial activation, neuroinflammation and alters neurotransmitter receptors in hippocampus, impairing spatial learning: reversal by sulforaphane. J Neuroinflammation. 13(1):41.
  • Hol EM, Pekny M. 2015. Glial fibrillary acidic protein (GFAP) and the astrocyte intermediate filament system in diseases of the central nervous system. Curr Opin Cell Biol. 32:121–130.
  • Hou XL, Tong Q, Wang WQ, Shi CY, Xiong W, Chen J, Liu X, Fang JG. 2015. Suppression of inflammatory responses by dihydromyricetin, a flavonoid from Ampelopsis grossedentata, via inhibiting the activation of NF-kappaB and MAPK signaling pathways. J Nat Prod. 78(7):1689–1696.
  • Jayakumar AR, Tong XY, Curtis KM, Ruiz-Cordero R, Abreu MT, Norenberg MD. 2014. Increased toll-like receptor 4 in cerebral endothelial cells contributes to the astrocyte swelling and brain edema in acute hepatic encephalopathy. J Neurochem. 128(6):890–903.
  • Leke R, Bak LK, Iversen P, Sorensen M, Keiding S, Vilstrup H, Ott P, Portela LV, Schousboe A, Waagepetersen HS. 2011. Synthesis of neurotransmitter GABA via the neuronal tricarboxylic acid cycle is elevated in rats with liver cirrhosis consistent with a high GABAergic tone in chronic hepatic encephalopathy. J Neurochem. 117(5):824–832.
  • Li XQ, Dong L, Liu ZH, Luo JY. 2005. Expression of gamma-aminobutyric acid A receptor subunits alpha1, beta1, gamma2 mRNA in rats with hepatic encephalopathy. WJG. 11(21):3319–3322.
  • Ling H, Zhu Z, Yang J, He J, Yang S, Wu D, Feng S, Liao D. 2018. Dihydromyricetin improves type 2 diabetes-induced cognitive impairment via suppressing oxidative stress and enhancing brain-derived neurotrophic factor-mediated neuroprotection in mice. Acta Biochim Biophys Sin. 50(3):298–306.
  • Liu D, Mao Y, Ding L, Zeng XA. 2019. Dihydromyricetin: a review on identification and quantification methods, biological activities, chemical stability, metabolism and approaches to enhance its bioavailability. Trends Food Sci Technol. 91:586–597.
  • Liu TT, Zeng Y, Tang K, Chen X, Zhang W, Xu XL. 2017. Dihydromyricetin ameliorates atherosclerosis in LDL receptor deficient mice. Atherosclerosis. 262:39–50.
  • Luo M, Guo JY, Cao WK. 2015. Inflammation: a novel target of current therapies for hepatic encephalopathy in liver cirrhosis. WJG. 21(41):11815–11824.
  • Parekh PJ, Balart LA. 2015. Ammonia and its role in the pathogenesis of hepatic encephalopathy. Clin Liver Dis. 19(3):529–537.
  • Ren Z, Yan P, Zhu L, Yang H, Zhao Y, Kirby BP, Waddington JL, Zhen X. 2018. Dihydromyricetin exerts a rapid antidepressant-like effect in association with enhancement of BDNF expression and inhibition of neuroinflammation. Psychopharmacology. 235(1):233–244.
  • Sepehrinezhad A, Zarifkar A, Namvar G, Shahbazi A, Williams R. 2020. Astrocyte swelling in hepatic encephalopathy: molecular perspective of cytotoxic edema. Metab Brain Dis. 35(4):559–578.
  • Song Q, Liu L, Yu J, Zhang J, Xu M, Sun L, Luo H, Feng Z, Meng G. 2017. Dihydromyricetin attenuated Ang II induced cardiac fibroblasts proliferation related to inhibitory of oxidative stress. Eur J Pharmacol. 807:159–167.
  • Squires JE, McKiernan P, Squires RH. 2018. Acute liver failure: an update. Clin Liver Dis. 22(4):773–805.
  • Stahel PF, Shohami E, Younis FM, Kariya K, Otto VI, Lenzlinger PM, Grosjean MB, Eugster HP, Trentz O, Kossmann T, et al. 2000. Experimental closed head injury: analysis of neurological outcome, blood-brain barrier dysfunction, intracranial neutrophil infiltration, and neuronal cell death in mice deficient in genes for pro-inflammatory cytokines. J Cereb Blood Flow Metab. 20(2):369–380.
  • Stravitz RT, Lee WM. 2019. Acute liver failure. Lancet. 394(10201):869–881.
  • Wijdicks EF. 2016. Hepatic encephalopathy. N Engl J Med. 375(17):1660–1670.
  • Zeng Y, Hua YQ, Wang W, Zhang H, Xu XL. 2020. Modulation of SIRT1-mediated signaling cascades in the liver contributes to the amelioration of nonalcoholic steatohepatitis in high fat fed middle-aged LDL receptor knockout mice by dihydromyricetin. Biochem Pharmacol. 175:113927.
  • Zhan G, Hua D, Huang N, Wang Y, Li S, Zhou Z, Yang N, Jiang R, Zhu B, Yang L, et al. 2019. Anesthesia and surgery induce cognitive dysfunction in elderly male mice: the role of gut microbiota. Aging. 11(6):1778–1790.
  • Zhang J, Chen Y, Luo H, Sun L, Xu M, Yu J, Zhou Q, Meng G, Yang S. 2018. Recent update on the pharmacological effects and mechanisms of dihydromyricetin. Front Pharmacol. 9:1204.