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Research Article

Pogostone inhibits the activity of CYP3A4, 2C9, and 2E1 in vitro

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Pages 530-534 | Received 10 Nov 2020, Accepted 12 Apr 2021, Published online: 29 Apr 2021

References

  • An X, Wu WR, Lai HL, Yang L, Tan XN, Huang ZB. 2019. Research progress in molecular pharmacognosy of Pogostemon cablin. Zhongguo Zhong Yao Za Zhi. 44:4781–4785.
  • Cao ZX, Yang YT, Yu S, Li YZ, Wang WW, Huang J, Xie XF, Xiong L, Lei S, Peng C. 2017. Pogostone induces autophagy and apoptosis involving PI3K/Akt/mTOR axis in human colorectal carcinoma HCT116 cells. J Ethnopharmacol. 202:20–27.
  • Chen H, Li Y, Wu X, Li C, Li Q, Qin Z, Yi Y, Chen J, Lai X, Su Z. 2013. LC-MS/MS determination of pogostone in rat plasma and its application in pharmacokinetic studies. Biomed Chromatogr. 27(9):1092–1099.
  • Chen H, Liao H, Liu Y, Zheng Y, Wu X, Su Z, Zhang X, Lai Z, Lai X, Lin ZX, et al. 2015. Protective effects of pogostone from Pogostemonis Herba against ethanol-induced gastric ulcer in rats. Fitoterapia. 100:110–117.
  • Chen XY, Chen HM, Liu YH, Zhang ZB, Zheng YF, Su ZQ, Zhang X, Xie JH, Liang YZ, Fu LD, et al. 2016. The gastroprotective effect of pogostone from Pogostemonis Herba against indomethacin-induced gastric ulcer in rats. Exp Biol Med. 241(2):193–204.
  • Curran MP. 2010. Amlodipine/atorvastatin: a review of its use in the treatment of hypertension and dyslipidaemia and the prevention of cardiovascular disease. Drugs. 70(2):191–213.
  • Gentz BA, Malan TP. Jr. 2001. Renal toxicity with sevoflurane: a storm in a teacup? Drugs. 61(15):2155–2162.
  • Guo L, Cui Y, Hao K. 2018. Effects of glycyrrhizin on the pharmacokinetics of asiatic acid in rats and its potential mechanism. Pharm Biol. 56(1):119–123.
  • Hendrikx JJ, Lagas JS, Rosing H, Schellens JH, Beijnen JH, Schinkel AH. 2013. P-glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel. Int J Cancer. 132(10):2439–2447.
  • Henningsson A, Marsh S, Loos WJ, Karlsson MO, Garsa A, Mross K, Mielke S, Viganò L, Locatelli A, Verweij J, et al. 2005. Association of CYP2C8, CYP3A4, CYP3A5, and ABCB1 polymorphisms with the pharmacokinetics of paclitaxel. Clin Cancer Res. 11(22):8097–8104.
  • Kamel EM, Lamsabhi AM. 2020. The quasi-irreversible inactivation of cytochrome P450 enzymes by paroxetine: a computational approach. Org Biomol Chem. 18(17):3334–3345.
  • Li H, Liu L, Xie L, Gan D, Jiang X. 2016. Effects of berberine on the pharmacokinetics of losartan and its metabolite EXP3174 in rats and its mechanism. Pharm Biol. 54(12):2886–2894.
  • Li YC, Xian YF, Su ZR, Ip SP, Xie JH, Liao JB, Wu DW, Li CW, Chen JN, Lin ZX, et al. 2014. Pogostone suppresses proinflammatory mediator production and protects against endotoxic shock in mice. J Ethnopharmacol. 157:212–221.
  • Liu L, Sun S, Rui H, Li XJPB. 2017. In vitro inhibitory effects of dihydromyricetin on human liver cytochrome P450 enzymes. Pharm Biol. 55(1):1868–1874.
  • Osawa K, Matsumoto T, Maruyama T, Takiguchi T, Okuda K, Takazoe I. 1990. Studies of the antibacterial activity of plant extracts and their constituents against periodontopathic bacteria. Bull Tokyo Dent Coll. 31(1):17–21.
  • Peng F, Wan F, Xiong L, Peng C, Dai M, Chen J. 2014. In vitro and in vivo antibacterial activity of Pogostone. Chin Med J. 127:4001–4005.
  • Schindler E, Hempelmann G. 1998. Perfusion and metabolism of liver and splanchnic nerve area under sevoflurane anesthesia. Anaesthesist. 47 (Suppl 1):S19–S23.
  • Su JY, Luo X, Zhang XJ, Deng XL, Su ZR, Zhou L, Li SS, Dai Z, Xu Y, Lai XP. 2015. Immunosuppressive activity of pogostone on T cells: blocking proliferation via S phase arrest. Int Immunopharmacol. 26(2):328–337.
  • Sun CY, Xu LQ, Zhang ZB, Chen CH, Huang YZ, Su ZQ, Guo HZ, Chen XY, Zhang X, Liu YH, et al. 2016. Protective effects of pogostone against LPS-induced acute lung injury in mice via regulation of Keap1-Nrf2/NF-kappaB signaling pathways. Int Immunopharmacol. 32:55–61.
  • Swamy MK, Sinniah UR. 2015. A comprehensive review on the phytochemical constituents and pharmacological activities of Pogostemon cablin Benth.: an aromatic medicinal plant of industrial importance. Molecules. 20(5):8521–8547.
  • Topletz AR, Dennison JB, Barbuch RJ, Hadden CE, Hall SD, Renbarger JL. 2013. The relative contributions of CYP3A4 and CYP3A5 to the metabolism of vinorelbine. Drug Metab Dispos. 41(9):1651–1661.
  • Wrighton SA, Stevens JC. 1992. The human hepatic cytochromes P450 involved in drug metabolism. Crit Rev Toxicol. 22(1):1–21.
  • Xiang Q, Li C, Zhao X, Cui YM. 2017. The influence of CYP3A5*3 and BCRPC421A genetic polymorphisms on the pharmacokinetics of felodipine in healthy Chinese volunteers. J Clin Pharm Ther. 42(3):345–349.
  • Yang HM, Zhuo JY, Sun CY, Nie J, Yuan J, Liu YL, Lin RF, Lai XP, Su ZR, Li YC. 2018. Pogostone attenuates TNF-alpha-induced injury in A549 cells via inhibiting NF-kappaB and activating Nrf2 pathways. Int Immunopharmacol. 62:15–22.
  • Yang J, Li Y, Li Y, Rui X, Du M, Wang Z. 2020. Effects of atorvastatin on pharmacokinetics of amlodipine in rats and its potential mechanism. Xenobiotica. 50(6):685–688.
  • Zhang JW, Liu Y, Cheng J, Li W, Ma H, Liu HT, Sun J, Wang LM, He YQ, Wang Y, et al. 2007. Inhibition of human liver cytochrome P450 by star fruit juice. J Pharm Pharm Sci. 10(4):496–503.
  • Zhang X, Feng P, Gao X, Wang B, Gou C, Bian RJPB. 2020. In vitro inhibitory effects of cepharanthine on human liver cytochrome P450 enzymes. Pharm Biol. 58(1):247–252.