2,935
Views
8
CrossRef citations to date
0
Altmetric
Research Article

Lappaol F, an anticancer agent, inhibits YAP via transcriptional and post-translational regulation

, , , , , & show all
Pages 617-626 | Received 08 Feb 2021, Accepted 24 Apr 2021, Published online: 19 May 2021

References

  • Amin A, Gali-Muhtasib H, Ocker M, Schneider-Stock R. 2009. Overview of major classes of plant-derived anticancer drugs. Int J Biomed Sci. 5(1):1–11.
  • Amin SA, Adhikari N, Jha T, Gayen S. 2018. A review on camptothecin analogs with promising cytotoxic profile. Anticancer Agents Med Chem. 18(13):1796–1814.
  • Bernabeu E, Cagel M, Lagomarsino E, Moretton M, Chiappetta DA. 2017. Paclitaxel: What has been done and the challenges remain ahead. Int J Pharm. 526(1-2):474–495.
  • Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. 2018. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 68(6):394–424.
  • Brodowska K, Al-Moujahed A, Marmalidou A, Meyer Zu Horste M, Cichy J, Miller JW, Gragoudas E, Vavvas DG. 2014. The clinically used photosensitizer verteporfin (VP) inhibits YAP-TEAD and human retinoblastoma cell growth in vitro without light activation. Exp Eye Res. 124:67–73.
  • Cao JJ, Zhao XM, Wang DL, Chen KH, Sheng X, Li WB, Li MC, Liu WJ, He J. 2014. YAP is overexpressed in clear cell renal cell carcinoma and its knockdown reduces cell proliferation and induces cell cycle arrest and apoptosis. Oncol Rep. 32(4):1594–1600.
  • Chan YS, Cheng LN, Wu JH, Chan E, Kwan YW, Lee SM, Leung GP, Yu PH, Chan SW. 2011. A review of the pharmacological effects of Arctium lappa (burdock). Inflammopharmacology. 19(5):245–254.
  • Chen X, Gu W, Wang Q, Fu X, Wang Y, Xu X, Wen Y. 2018. C-MYC and BCL-2 mediate YAP-regulated tumorigenesis in OSCC. Oncotarget. 9(1):668–679.
  • He C, Mao D, Hua G, Lv X, Chen X, Angeletti PC, Dong J, Remmenga SW, Rodabaugh KJ, Zhou J, et al. 2015. The Hippo/YAP pathway interacts with EGFR signaling and HPV oncoproteins to regulate cervical cancer progression. EMBO Mol Med. 7(11):1426–1449.
  • Jang W, Kim T, Koo JS, Kim SK, Lim DS. 2017. Mechanical cue-induced YAP instructs Skp2-dependent cell cycle exit and oncogenic signaling. Embo J. 36(17):2510–2528.
  • Kim HM, Jung WH, Koo JS. 2015. Expression of Yes-associated protein (YAP) in metastatic breast cancer. Int J Clin Exp Pathol. 8(9):11248–11257.
  • Lamar JM, Stern P, Liu H, Schindler JW, Jiang ZG, Hynes RO. 2012. The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain. Proc Natl Acad Sci USA. 109(37):E2441–E2450.
  • Li X, Liu Y, Zhang C, Niu Q, Wang H, Che C, Xie M, Zhou B, Xu Y, Zhang Q, et al. 2017. Stiehopus japonieus acidic mucopolysaccharide inhibits the proliferation of pancreatic cancer SW1990 cells through Hippo-YAP pathway. Oncotarget. 8(10):16356–16366.
  • Liu Z, Zeng W, Wang S, Zhao X, Guo Y, Yu P, Yin X, Liu C, Huang T. 2017. A potential role for the Hippo pathway protein, YAP, in controlling proliferation, cell cycle progression, and autophagy in BCPAP and KI thyroid papillary carcinoma cells. Am J Transl Res. 9(7):3212–3223.
  • Martino E, Casamassima G, Castiglione S, Cellupica E, Pantalone S, Papagni F, Rui M, Siciliano AM, Collina S. 2018. Vinca alkaloids and analogues as anti-cancer agents: Looking back, peering ahead. Bioorg Med Chem Lett. 28(17):2816–2826.
  • Meng Z, Lv Q, Lu J, Yao H, Lv X, Jiang F, Lu A, Zhang G. 2016. Prodrug strategies for paclitaxel. IJMS. 17(5):796.
  • Mizuno T, Murakami H, Fujii M, Ishiguro F, Tanaka I, Kondo Y, Akatsuka S, Toyokuni S, Yokoi K, Osada H, et al. 2012. YAP induces malignant mesothelioma cell proliferation by upregulating transcription of cell cycle-promoting genes. Oncogene. 31(49):5117–5122.
  • Oku Y, Nishiya N, Shito T, Yamamoto R, Yamamoto Y, Oyama C, Uehara Y. 2015. Small molecules inhibiting the nuclear localization of YAP/TAZ for chemotherapeutics and chemosensitizers against breast cancers. FEBS Open Bio. 5:542–549.
  • Park SY, Hong SS, Han XH, Hwang JS, Lee D, Ro JS, Hwang BY. 2007. Lignans from Arctium lappa and their inhibition of LPS-induced nitric oxide production. Chem Pharm Bull (Tokyo). 55(1):150–152.
  • Pei T, Li Y, Wang J, Wang H, Liang Y, Shi H, Sun B, Yin D, Sun J, Song R, et al. 2015. YAP is a critical oncogene in human cholangiocarcinoma. Oncotarget. 6(19):17206–17220.
  • Rosenbluh J, Nijhawan D, Cox AG, Li X, Neal JT, Schafer EJ, Zack TI, Wang X, Tsherniak A, Schinzel AC, et al. 2012. β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis. Cell. 151(7):1457–1473.
  • Sambandam SAT, Kasetti RB, Xue L, Dean DC, Lu Q, Li Q. 2015. 14-3-3σ regulates keratinocyte proliferation and differentiation by modulating Yap1 cellular localization. J Invest Dermatol. 135(6):1621–1628.
  • Schumacher B, Skwarczynska M, Rose R, Ottmann C. 2010. Structure of a 14-3-3σ-YAP phosphopeptide complex at 1.15 Å resolution. Acta Crystallogr Sect F Struct Biol Cryst Commun. 66(Pt 9):978–984.
  • Sharif GM, Wellstein A. 2015. Cell density regulates cancer metastasis via the Hippo pathway. Future Oncol. 11(24):3253–3260.
  • Sirikantaramas S, Asano T, Sudo H, Yamazaki M, Saito K. 2007. Camptothecin: Therapeutic potential and biotechnology. Curr Pharm Biotechnol. 8(4):196–202.
  • Song J, Xie LX, Zhang XY, Hu P, Long MF, Xiong F, Huang J, Ye XQ. 2018. Role of YAP in lung cancer resistance to cisplatin. Oncol Lett. 16(3):3949–3954.
  • Song Y, Li X, Liu Y, Hu Y, Yang R. 2019. Arctigenin improves lipid metabolism by regulating AMP-activated protein kinase and downstream signaling pathways. J Cell Biochem. 120(8):13275–13288.
  • Steinhardt AA, Gayyed MF, Klein AP, Dong J, Maitra A, Pan D, Montgomery EA, Anders RA. 2008. Expression of Yes-associated protein in common solid tumors. Hum Pathol. 39(11):1582–1589.
  • Su S, Cheng X, Wink M. 2015. Natural lignans from Arctium lappa modulate P-glycoprotein efflux function in multidrug resistant cancer cells. Phytomedicine. 22(2):301–307.
  • Su S, Wink M. 2015. Natural lignans from Arctium lappa as antiaging agents in Caenorhabditis elegans. Phytochemistry. 117:340–350.
  • Sun Q, Liu K, Shen X, Jin W, Jiang L, Sheikh MS, Hu Y, Huang Y. 2014. Lappaol F, a novel anticancer agent isolated from plant Arctium lappa L. Mol Cancer Ther. 13(1):49–59.
  • Takeuchi S, Kasamatsu A, Yamatoji M, Nakashima D, Endo-Sakamoto Y, Koide N, Takahara T, Shimizu T, Iyoda M, Ogawara K, et al. 2017. TEAD4-YAP interaction regulates tumoral growth by controlling cell-cycle arrest at the G1 phase. Biochem Biophys Res Commun. 486(2):385–390.
  • Wang C, Zhu X, Feng W, Yu Y, Jeong K, Guo W, Lu Y, Mills GB. 2016. Verteporfin inhibits YAP function through up-regulating 14-3-3σ sequestering YAP in the cytoplasm. Am J Cancer Res. 6(1):27–37.
  • Wang L, Shi S, Guo Z, Zhang X, Han S, Yang A, Wen W, Zhu Q. 2013. Overexpression of YAP and TAZ is an independent predictor of prognosis in colorectal cancer and related to the proliferation and metastasis of colon cancer cells. PLoS One. 8(6):e65539.
  • Wu L, Yang X. 2018. Targeting the Hippo pathway for breast cancer therapy. Cancers (Basel). 10(11):422.
  • Xia Y, Chang T, Wang Y, Liu Y, Li W, Li M, Fan HY. 2014. YAP promotes ovarian cancer cell tumorigenesis and is indicative of a poor prognosis for ovarian cancer patients. PLoS One. 9(3):e91770.
  • Yang S, Zhang L, Liu M, Chong R, Ding SJ, Chen Y, Dong J. 2013. CDK1 phosphorylation of YAP promotes mitotic defects and cell motility and is essential for neoplastic transformation. Cancer Res. 73(22):6722–6733.
  • Zeng Q, Hong W. 2008. The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals. Cancer Cell. 13(3):188–192.
  • Zhao B, Li L, Tumaneng K, Wang CY, Guan KL. 2010. A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF (beta-TRCP). Genes Dev. 24(1):72–85.
  • Zhao B, Wei X, Li W, Udan RS, Yang Q, Kim J, Xie J, Ikenoue T, Yu J, Li L, et al. 2007. Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. Genes Dev. 21(21):2747–2761.
  • Zhao Y, Khanal P, Savage P, She YM, Cyr TD, Yang X. 2014. YAP-induced resistance of cancer cells to antitubulin drugs is modulated by a Hippo-independent pathway. Cancer Res. 74(16):4493–4503.
  • Zhu RJ, Shen XL, Dai LL, Ai XY, Tian RH, Tang R, Hu YJ. 2014. Total aglycones from Marsdenia tenacissima increases antitumor efficacy of paclitaxel in nude mice. Molecules. 19(9):13965–13975.