Effects of Jian Pi Qing Chang Hua Shi decoction on mucosal injuries in a 2,4,6-trinitrobenzene sulphonic acid-induced inflammatory bowel disease rat model

References

• Akanda MR, Nam HH, Tian W, Islam A, Choo BK, Park BY. 2018. Regulation of JAK2/STAT3 and NF-κB signal transduction pathways; Veronica polita alleviates dextran sulfate sodium-induced murine colitis. Biomed Pharmacother. 100:296–303.
   PubMed Web of Science ®Google Scholar
• Arab HH, Al-Shorbagy MY, Abdallah DM, Nassar NN. 2014. Telmisartan attenuates colon inflammation, oxidative perturbations and apoptosis in a rat model of experimental inflammatory bowel disease. PLoS One. 9(5):e97193.
   PubMed Web of Science ®Google Scholar
• Babbs CF. 1992. Oxygen radicals in ulcerative colitis. Free Radic Biol Med. 13(2):169–181.
   PubMed Web of Science ®Google Scholar
• Bamba T, Yamamoto T, Umegae S, Matsumoto K. 2014. Effects of preoperative leukocytapheresis on inflammatory cytokines following surgery for ulcerative colitis: a prospective randomized study. J Clin Apher. 29(2):107–112.
   PubMed Web of Science ®Google Scholar
• Barnes EL, Lightner AL, Regueiro M. 2020. Perioperative and postoperative management of patients with Crohn's disease and ulcerative colitis. Clin Gastroenterol Hepatol. 18(6):1356–1366.
   PubMed Web of Science ®Google Scholar
• Bitton A, Peppercorn MA, Antonioli DA, Niles JL, Shah S, Bousvaros A, Ransil B, Wild G, Cohen A, Edwardes MD, et al. 2001. Clinical, biological, and histologic parameters as predictors of relapse in ulcerative colitis. Gastroenterology. 120(1):13–20.
   PubMed Web of Science ®Google Scholar
• Chamanara M, Rashidian A, Mehr SE, Dehpour AR, Shirkohi R, Akbarian R, Abdollahi A, Rezayat SM. 2019. Melatonin ameliorates TNBS-induced colitis in rats through the melatonin receptors: involvement of TLR4/MyD88/NF-κB signalling pathway. Inflammopharmacology. 27(2):361–371.
   PubMed Web of Science ®Google Scholar
• Colombo BB, Fattori V, Guazelli CFS, Zaninelli TH, Carvalho TT, Ferraz CR, Bussmann AJC, Ruiz-Miyazawa KW, Baracat MM, Casagrande R, et al. 2018. Vinpocetine ameliorates acetic acid-induced colitis by inhibiting NF-κB Activation in Mice. Inflammation. 41(4):1276–1289.
   PubMed Web of Science ®Google Scholar
• Cota D, Mishra S, Shengule S. 2019. Beneficial role of Terminalia arjuna hydro-alcoholic extract in colitis and its possible mechanism. J Ethnopharmacol. 230:117–125.
   PubMed Web of Science ®Google Scholar
• Duan YQ, Cheng YX, Liang YJ, Cheng WD, Du J, Yang XY, Wang Y. 2015. Intervention of Qi-activating and spleen-strengthening herbs on Ca2+/CaMK II signaling pathways key factors ic n skeletal muscle tissue of rats with spleen-qi deficiency. Zhong Yao Cai. 38:562–566.
   PubMedGoogle Scholar
• Evgenikos N, Bartolo DC, Hamer-Hodges DW, Ghosh S. 2002. Assessment of ileoanal pouch inflammation by interleukin 1 beta and interleukin 8 concentrations in the gut lumen. Dis Colon Rectum. 45(2):249–255.
   PubMed Web of Science ®Google Scholar
• Fang W, Zhu S, Niu Z, Yin Y. 2019. The protective effect of syringic acid on dextran sulfate sodium-induced experimental colitis in BALB/c mice. Drug Dev Res. 80(6):731–740.
   PubMed Web of Science ®Google Scholar
• Feuerstein JD, Moss AC, Farraye FA. 2019. Ulcerative colitis. Mayo Clin Proc. 94(7):1357–1373.
   PubMed Web of Science ®Google Scholar
• Gong Y, Niu W, Tang Y, Zhang Q, Liu S, Liu X, Wang X, Xu Y. 2019. Aggravated mucosal and immune damage in a mouse model of ulcerative colitis with stress. Exp Ther Med. 17:2341–2348.
   PubMed Web of Science ®Google Scholar
• Gong YX, Sun Y, Xiang XR. 1995. Transmission electron microscopic observation on the liver and cerebral cortex in aging mice treated with Sijunzi decoction. Zhongguo Zhong Xi Yi Jie He Za Zhi. 15(6):359–361.
   PubMedGoogle Scholar
• Güvenç M, Cellat M, Özkan H, Tekeli İO, Uyar A, Gökçek İ, İşler CT, Yakan A. 2019. Protective effects of tyrosol against DSS-induced ulcerative colitis in rats. Inflammation. 42(5):1680–1691.
   PubMed Web of Science ®Google Scholar
• Hamamoto N, Maemura K, Hirata I, Murano M, Sasaki S, Katsu K. 1999. Inhibition of dextran sulphate sodium (DSS)-induced colitis in mice by intracolonically administered antibodies against adhesion molecules (endothelial leucocyte adhesion molecule-1 (ELAM-1) or intercellular adhesion molecule-1 (ICAM-1)). Clin Exp Immunol. 117(3):462–468.
   PubMed Web of Science ®Google Scholar
• Han KH, Park JM, Jeong M, Han YM, Go EJ, Park J, Kim H, Han JG, Kwon O, Hahm KB. 2017. Heme oxygenase-1 induction and anti-inflammatory actions of Atractylodes macrocephala and Taraxacum herba extracts prevented colitis and was more effective than sulfasalazine in preventing relapse. Gut Liver. 11(5):655–666.
   PubMed Web of Science ®Google Scholar
• Hanai H, Iida T, Yamada M, Sato Y, Takeuchi K, Tanaka T, Kondo K, Kikuyama M, Maruyama Y, Iwaoka Y. 2006. Effects of adacolumn selective leukocytapheresis on plasma cytokines during active disease in patients with active ulcerative colitis. WJG. 12(21):3393–3399.
   PubMed Web of Science ®Google Scholar
• Hansberry DR, Shah K, Agarwal P, Agarwal N. 2017. Fecal myeloperoxidase as a biomarker for inflammatory bowel disease. Cureus. 9(1):e1004.
   PubMed Web of Science ®Google Scholar
• Jin X, Song S, Wang J, Zhang Q, Qiu F, Zhao F. 2016. Tiliroside, the major component of Agrimonia pilosa ledeb ethanol extract, inhibits MAPK/JNK/p38-mediated inflammation in lipopolysaccharide-activated RAW 264.7 macrophages. Exp Ther Med. 12(1):499–505.
   PubMed Web of Science ®Google Scholar
• Joh EH, Lee IA, Han SJ, Chae S, Kim DH. 2010. Lancemaside A ameliorates colitis by inhibiting NF-kappaB activation in TNBS-induced colitis mice. Int J Colorectal Dis. 25(5):545–551.
   PubMed Web of Science ®Google Scholar
• Karaboga I, Demirtas S, Karaca T. 2017. Investigation of the relationship between the Th17/IL-23 pathway and innate-adaptive immune system in TNBS-induced colitis in rats. Iran J Basic Med Sci. 20(8):870–879.
   PubMed Web of Science ®Google Scholar
• Kaulmann A, Bohn T. 2016. Bioactivity of polyphenols: preventive and adjuvant strategies toward reducing inflammatory bowel diseases-promises, perspectives, and pitfalls. Oxid Med Cell Longev. 2016:9346470.
   PubMed Web of Science ®Google Scholar
• Komine-Aizawa S, Masuda H, Mazaki T, Shiono M, Hayakawa S, Takayama T. 2015. Plasma osteopontin predicts inflammatory bowel disease activities. Int Surg. 100(1):38–43.
   PubMed Web of Science ®Google Scholar
• Li CL, Tan LH, Wang YF, Luo CD, Chen HB, Lu Q, Li YC, Yang XB, Chen JN, Liu YH, et al. 2019. Comparison of anti-inflammatory effects of berberine, and its natural oxidative and reduced derivatives from Rhizoma Coptidis in vitro and in vivo. Phytomedicine. 52:272–283.
   PubMed Web of Science ®Google Scholar
• Li GH, Li YR, Jiao P, Zhao Y, Hu HX, Lou HX, Shen T. 2018. Therapeutic potential of Salviae miltiorrhizae Radix et Rhizoma against human diseases based on activation of Nrf2-mediated antioxidant defense system: bioactive constituents and mechanism of action. Oxid Med Cell Longev. 2018:7309073.
   PubMed Web of Science ®Google Scholar
• Liu Q, Cai G. 2007. Content of somatostatin and cholecystokinin-8 in hypothalamus and colons in a rat model of spleen-deficiency syndrome. J Chin Integr Med. 5(5):555–558.
   PubMedGoogle Scholar
• Lu Y, Li L, Zhang JW, Zhong XQ, Wei JA, Han L. 2018. Total polysaccharides of the Sijunzi decoction attenuate tumor necrosis factor-α-induced damage to the barrier function of a Caco-2 cell monolayer via the nuclear factor-κB-myosin light chain kinase-myosin light chain pathway. World J Gastroenterol. 24(26):2867–2877.
   PubMed Web of Science ®Google Scholar
• Lu Y, Lin H, Zhang J, Wei J, Sun J, Han L. 2017. Sijunzi decoction attenuates 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitis in rats and ameliorates TNBS-induced claudin-2 damage via NF-κB pathway in Caco2 cells. BMC Complement Altern Med. 17(1):35.
   PubMedGoogle Scholar
• Mahmud N, O'Connell MA, Stinson J, Goggins MG, Weir DG, Kelleher D. 1995. Tumour necrosis factor-alpha and microalbuminuria in patients with inflammatory bowel disease. Eur J Gastroenterol Hepatol. 7:215–219.
   PubMed Web of Science ®Google Scholar
• Masoodi I, Tijjani BM, Wani H, Hassan NS, Khan AB, Hussain S. 2011. Biomarkers in the management of ulcerative colitis: a brief review. Ger Med Sci. 9:1–7.
   Google Scholar
• Menghini L, Ferrante C, Leporini L, Recinella L, Chiavaroli A, Leone S, Pintore G, Vacca M, Orlando G, Brunetti L. 2016. An hydroalcoholic chamomile extract modulates inflammatory and immune response in HT29 cells and isolated rat colon. Phytother Res. 30(9):1513–1518.
   PubMed Web of Science ®Google Scholar
• Murthy SN, Cooper HS, Shim H, Shah RS, Ibrahim SA, Sedergran DJ. 1993. Treatment of dextran sulfate sodium-induced murine colitis by intracolonic cyclosporin. Dig Dis Sci. 38(9):1722–1734.
   PubMed Web of Science ®Google Scholar
• Muthas D, Reznichenko A, Balendran CA, Bottcher G, Clausen IG, Karrman Mardh C, Ottosson T, Uddin M, MacDonald TT, Danese S, et al. 2017. Neutrophils in ulcerative colitis: a review of selected biomarkers and their potential therapeutic implications. Scand J Gastroenterol. 52(2):125–135.
   PubMed Web of Science ®Google Scholar
• Niederau C, Backmerhoff F, Schumacher B, Niederau C. 1997. Inflammatory mediators and acute phase proteins in patients with Crohn's disease and ulcerative colitis. Hepatogastroenterology. 44(13):90–107.
   PubMedGoogle Scholar
• Nikkhah-Bodaghi M, Maleki I, Agah S, Hekmatdoost A. 2019. Zingiber officinale and oxidative stress in patients with ulcerative colitis: a randomized, placebo-controlled, clinical trial. Complement Ther Med. 43:1–6.
   PubMed Web of Science ®Google Scholar
• Ojuawo A, St Louis D, Lindley KJ, Milla PJ. 1997. Non-infective colitis in infancy: evidence in favour of minor immunodeficiency in its pathogenesis. Arch Dis Child. 76(4):345–348.
   PubMed Web of Science ®Google Scholar
• Oliveira NVdM, Souza BdS, Moita LA, Oliveira LES, Brito FC, Magalhães DA, Batista JA, Sousa SG, Brito TVd, Sousa FBdM, et al. 2019. Proteins from Plumeria pudica latex exhibit protective effect in acetic acid induced colitis in mice by inhibition of pro-inflammatory mechanisms and oxidative stress. Life Sci. 231:116535.
   PubMed Web of Science ®Google Scholar
• Pedersen J, Coskun M, Soendergaard C, Salem M, Nielsen OH. 2014. Inflammatory pathways of importance for management of inflammatory bowel disease. World J Gastroenterol. 20(1):64–77.
   PubMed Web of Science ®Google Scholar
• Perrier C, Rutgeerts P. 2011. Cytokine blockade in inflammatory bowel diseases. Immunotherapy. 3(11):1341–1352.
   PubMed Web of Science ®Google Scholar
• Reyna-Garfias H, Miliar A, Jarillo-Luna A, Rivera-Aguilar V, Pacheco-Yepez J, Baeza I, Campos-Rodriguez R. 2010. Repeated restraint stress increases IgA concentration in rat small intestine. Brain Behav Immun. 24(1):110–118.
   PubMed Web of Science ®Google Scholar
• Roessner A, Kuester D, Malfertheiner P, Schneider-Stock R. 2008. Oxidative stress in ulcerative colitis-associated carcinogenesis. Pathol Res Pract. 204(7):511–524.
   PubMed Web of Science ®Google Scholar
• Samman FS, Elaidy SM, Essawy SS, Hassan MS. 2018. New insights on the modulatory roles of metformin or alpha-lipoic acid versus their combination in dextran sulfate sodium-induced chronic colitis in rats. Pharmacol Rep. 70(3):488–496.
   PubMed Web of Science ®Google Scholar
• Seidelin JB. 2015. Regulation of antiapoptotic and cytoprotective pathways in colonic epithelial cells in ulcerative colitis. Scand J Gastroenterol. 50 (Suppl 1):1–29.
   PubMedGoogle Scholar
• Silvia Melgar AK, Erik M. 2005. Acute colitis induced by dextran sulfate sodium progresses to chronicity in C57BL/6 but not in BALB/c mice: correlation between symptoms and inflammation. Am J Physiol Gastrointest Liver Physiol. 288:1328–1338.
   Web of Science ®Google Scholar
• Street ME, de'Angelis G, Camacho-Hubner C, Giovannelli G, Ziveri MA, Bacchini PL, Bernasconi S, Sansebastiano G, Savage MO. 2004. Relationships between serum IGF-1, IGFBP-2, interleukin-1 beta and interleukin-6 in inflammatory bowel disease. Horm Res. 61:159–164.
   PubMedGoogle Scholar
• Strus M, Okoń K, Nowak B, Pilarczyk-Zurek M, Heczko P, Gawda A, Ciszek-Lenda M, Skowron B, Baranowska A, Marcinkiewicz J. 2015. Distinct effects of Lactobacillus plantarum KL30B and Escherichia coli 3A1 on the induction and development of acute and chronic inflammation. Cent Eur J Immunol. 40(4):420–430.
   PubMed Web of Science ®Google Scholar
• Szczeklik K, Owczarek D, Cibor D, Cześnikiewicz-Guzik M, Krzyściak P, Krawczyk A, Mach T, Karczewska E, Krzyściak W. 2019. Relative homogeneity of oral bacterial oral in Crohn's disease compared to ulcerative colitis and its connections with antioxidant defense – preliminary report. Folia Med Cracov. 59(1):15–35.
   PubMedGoogle Scholar
• Tatiya-Aphiradee N, Chatuphonprasert W, Jarukamjorn K. 2018. Immune response and inflammatory pathway of ulcerative colitis. J Basic Clin Physiol Pharmacol. 30(1):1–10.
   PubMedGoogle Scholar
• Thurgate LE, Lemberg DA, Day AS, Leach ST. 2019. An overview of inflammatory bowel disease unclassified in children. Inflamm Intest Dis. 4(3):97–103.
   PubMedGoogle Scholar
• Tian JF, Li JD, Lei Y. 2012. Clinical features of acute myocardial infarction inpatients in 26 level three class A Chinese medicine hospitals in China and the investigation of treatment. Zhongguo Zhong Xi Yi Jie He Za Zhi. 32:329–332.
   PubMedGoogle Scholar
• Tian R, Gong ZH, Yang XY, Zhu LM, Duan YQ, Cheng YX, Du J, Wang Y. 2015. Study on interference effect of Sijunzi decoction on brain-gut CaM/CaMK II of spleen Qi deficiency syndrome rats. Zhongguo Zhong Yao za Zhi. 40:4075–4079.
   PubMedGoogle Scholar
• Traish A, Bolanos J, Nair S, Saad F, Morgentaler A. 2018. Do androgens modulate the pathophysiological pathways of inflammation? Appraising the contemporary evidence. J Clin Med. 7:1–33.
   Web of Science ®Google Scholar
• Wallace KL, Zheng LB, Kanazawa Y, Shih DQ. 2014. Immunopathology of inflammatory bowel disease. World J Gastroenterol. 20(1):6–21.
   PubMed Web of Science ®Google Scholar
• Wang JP, Dong LN, Wang M, Guo J, Zhao YQ. 2019. MiR-146a regulates the development of ulcerative colitis via mediating the TLR4/MyD88/NF-κB signaling pathway. Eur Rev Med Pharmacol Sci. 23(5):2151–2157.
   PubMed Web of Science ®Google Scholar
• Wang SY, Tao P, Hu HY, Yuan JY, Zhao L, Sun BY, Zhang WJ, Lin J. 2017. Effects of initiating time and dosage of Panax notoginseng on mucosal microvascular injury in experimental colitis. World J Gastroenterol. 23(47):8308–8320.
   PubMed Web of Science ®Google Scholar
• Wang W, Yang B, Wang L, Liang R, Chen C, Hu N, Cheng L, Yang Y, Yin X, Gao S, et al. 2011. Antiatherogenic effect of Radix Salviae miltiorrhizae and fructus Crataegi on experimental atherosclerosis in rats. Zhongguo Zhong Yao Za Zhi. 36(6):784–789.
   PubMedGoogle Scholar
• Wang X, Saud SM, Zhang X, Li W, Hua B. 2019. Protective effect of Shaoyao decoction against colorectal cancer via the Keap1-Nrf2-ARE signaling pathway. J Ethnopharmacol. 241:111981.
   PubMed Web of Science ®Google Scholar
• Wu B, Xuan ZR. 2007. Progress in research on applying Sijunzi decoction in treating digestive malignant tumor. Chin J Integr Med. 13(2):156–159.
   PubMed Web of Science ®Google Scholar
• Wu J, Zhang H, Hu B, Yang L, Wang P, Wang F, Meng X. 2016. Coptisine from Coptis chinensis inhibits production of inflammatory mediators in lipopolysaccharide-stimulated RAW 264.7 murine macrophage cells. Eur J Pharmacol. 780:106–114.
   PubMed Web of Science ®Google Scholar
• Wu P, Guo Y, Jia F, Wang X. 2015. The effects of armillarisin A on serum IL-1β and IL-4 and in treating Ulcerative colitis. Cell Biochem Biophys. 72(1):103–106.
   PubMed Web of Science ®Google Scholar
• Xiao B, Chen G, Lan Z. 2005. Study on the effect of promoting intelligence development and preventing hypoxia/reoxygenation injury of selenium-banqiao-Codonopsis pilosula-overground part in mice. Zhong Yao Cai. 28:688–690.
   PubMedGoogle Scholar
• Yang JH, Hwang YH, Gu MJ, Cho WK, Ma JY. 2015. Ethanol extracts of Sanguisorba officinalis L. suppress TNF-α/IFN-γ-induced pro-inflammatory chemokine production in HaCaT cells. Phytomedicine. 22(14):1262–1268.
   PubMed Web of Science ®Google Scholar
• Yang Y, Zhu X, Qin Y, Chen G, Zhou J, Li L, Guan J, Ma L, Xue Y, Li C. 2017. The anti-inflammatory effect of Guchangzhixie-Pill by reducing colonic EC cell hyperplasia and serotonin availability in an ulcerative colitis rat model. Evid Based Complement Alternat Med. 2017:1–11.
   Web of Science ®Google Scholar
• Ye T, Xiong D, Chen L, Li Y, Gong S, Zhang L, Li B, Pan J, Qian J, Qu H. 2020. Effect of Danshen on TLR2-triggered inflammation in macrophages. Phytomedicine. 70:153228.
   PubMed Web of Science ®Google Scholar
• Yukitake H, Kimura H, Suzuki H, Tajima Y, Sato Y, Imaeda T, Kajino M, Takizawa M. 2011. BTZO-15, an are-activator, ameliorates DSS- and TNBS-induced colitis in rats. PLoS One. 6(8):e23256.
   PubMed Web of Science ®Google Scholar
• Zhang B, Zeng M, Li M, Kan Y, Li B, Xu R, Wu Y, Wang S, Zheng X, Feng W. 2019. Protopine protects mice against LPS-induced acute kidney injury by inhibiting apoptosis and inflammation via the TLR4 signaling pathway. Molecules. 25(1):15.
   PubMed Web of Science ®Google Scholar
• Zhang C, Jiang M, Lu A. 2013. Considerations of traditional Chinese medicine as adjunct therapy in the management of ulcerative colitis. Clin Rev Allergy Immunol. 44(3):274–283.
   PubMed Web of Science ®Google Scholar
• Zhang J, Ding L, Wang B, Ren G, Sun A, Deng C, Wei X, Mani S, Wang Z, Dou W. 2015. Notoginsenoside R1 attenuates experimental inflammatory bowel disease via pregnane X receptor activation. J Pharmacol Exp Ther. 352(2):315–324.
   PubMed Web of Science ®Google Scholar
• Zhang M, Zhang Z, Xia T. 1999. Effect of Sijunzi decoction on serum soluble intercellular adhesive molecule-1, interleukin-15 and monocyte antibody-dependent cell-mediated cytotoxicity in patients of spleen-deficiency. Zhongguo Zhong Xi Yi Jie He Za Zhi. 19:270–272.
   PubMedGoogle Scholar
• Zhang Z, Yang L, Wang B, Zhang L, Zhang Q, Li D, Zhang S, Gao H, Wang X. 2017. Protective role of liriodendrin in mice with dextran sulphate sodium-induced ulcerative colitis. Int Immunopharmacol. 52:203–210.
   PubMed Web of Science ®Google Scholar
• Zhao X, Li L, Li X, Li J, Wang D, Zhang H. 2019. The relationship between serum bilirubin and inflammatory bowel disease. Mediators Inflamm. 2019:5256460.
   PubMed Web of Science ®Google Scholar
• Zhou Y, Tao H, Wang A, Zhong Z, Wu X, Wang M, Bian Z, Wang S, Wang Y. 2019. Chinese herb pair Paeoniae Radix alba and Atractylodis macrocephalae Rhizoma suppresses LPS-induced inflammatory response through inhibiting MAPK and NF-κB pathway. Chin Med. 14:2.
   PubMed Web of Science ®Google Scholar
• Zou W, Zhou H, Hu J, Zhang L, Tang Q, Wen X, Xiao Z, Wang W. 2017. Rhizoma Smilacis glabrae inhibits pathogen-induced upper genital tract inflammation in rats through suppression of NF-kappaB pathway. J Ethnopharmacol. 202:103–113.
   PubMed Web of Science ®Google Scholar
• Zwolinska-Wcislo M, Brzozowski T, Budak A, Kwiecien S, Sliwowski Z, Drozdowicz D, Trojanowska D, Rudnicka-Sosin L, Mach T, Konturek SJ. 2009. Effect of Candida colonization on human ulcerative colitis and the healing of inflammatory changes of the colon in the experimental model of colitis ulcerosa. J Physiol Pharmacol. 60:107–118.
   PubMed Web of Science ®Google Scholar