Selenium-containing protein from selenium-enriched Spirulina platensis antagonizes oxygen glucose deprivation-induced neurotoxicity by inhibiting ROS-mediated oxidative damage through regulating MPTP opening

References

• Adams JM, Cory S. 1998. The Bcl-2 protein family: arbiters of cell survival. Science. 281:1322–1326.
   PubMed Web of Science ®Google Scholar
• Andrabi SS, Parvez S, Tabassum H. 2020. Ischemic stroke and mitochondria: mechanisms and targets. Protoplasma. 257:335–343.
   PubMed Web of Science ®Google Scholar
• Avan A, Digaleh H, Di NM, Stranges S, Behrouz R, Shojaeianbabaei G, Amiri A, Tabrizi R, Mokhber N, Spence JD, et al. 2019. Socioeconomic status and stroke incidence, prevalence, mortality, and worldwide burden: an ecological analysis from the Global Burden of Disease Study 2017. BMC Med. 17(1):1741–7015.
   Web of Science ®Google Scholar
• Balaban H, Naziroglu M, Demirci K, Ovey IS. 2017. The protective role of selenium on scopolamine-induced memory impairment, oxidative stress, and apoptosis in aged rats: the involvement of TRPM2 and TRPV1 channels. Mol Neurobiol. 54:2852–2868.
   PubMed Web of Science ®Google Scholar
• Barrientos SA, Martinez NW, Yoo S, Jara JS, Zamorano S, Hetz C, Twiss JL, Alvarez J, Court FA. 2011. Axonal degeneration is mediated by the mitochondrial permeability transition pore. J Neurosci. 31:966–978.
   PubMed Web of Science ®Google Scholar
• Chen T, Wong YS, Zheng W. 2006. Purification and characterization of selenium-containing phycocyanin from selenium-enriched Spirulina platensis. Phytochemistry. 67:2424–2430.
   PubMed Web of Science ®Google Scholar
• Christophe M, Nicolas S. 2006. Mitochondria: a target for neuroprotective interventions in cerebral ischemia-reperfusion. Curr Pharm Design. 12:739–757.
   PubMed Web of Science ®Google Scholar
• Collaborators GBDN. 2019. Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol. 18:459–480.
   PubMed Web of Science ®Google Scholar
• Drose S, Stepanova A, Galkin A. 2016. Ischemic A/D transition of mitochondrial complex I and its role in ROS generation. Biochim Biophys Acta. 1857:946–957.
   PubMed Web of Science ®Google Scholar
• Fairweather-Tait SJ, Bao Y, Broadley MR, Collings R, Ford D, Hesketh JE, Hurst R. 2011. Selenium in human health and disease. Antioxid Redox Sign. 14:1337–1383.
   PubMed Web of Science ®Google Scholar
• Fan C, Jiang J, Yin X, Wong K-H, Zheng W, Chen T. 2012. Purification of selenium-containing allophycocyanin from selenium-enriched Spirulina platensis and its hepatoprotective effect against t-BOOH-induced apoptosis. Food Chem. 134(1):253.
   Web of Science ®Google Scholar
• Farajdokht F, Mohaddes G, Karimi-Sales E, Kafshdooz T, Mahmoudi J, Aberoumandi SM, Karimi P. 2018. Inhibition of PTEN protects PC12 cells against oxygen-glucose deprivation induced cell death through mitoprotection. Brain Res. 1692:100–109.
   PubMed Web of Science ®Google Scholar
• Godoi GL, de Oliveira Porciuncula L, Schulz JF, Kaufmann FN, da Rocha JB, de Souza DO, Ghisleni G, de Almeida HL, Jr. 2013. Selenium compounds prevent amyloid beta-peptide neurotoxicity in rat primary hippocampal neurons. Neurochem Res. 38:2359–2363.
   PubMed Web of Science ®Google Scholar
• Hao Z, Duncan GS, Chang CC, Elia A, Fang M, Wakeham A, Okada H, Calzascia T, Jang Y, You-Ten A, et al. 2005. Specific ablation of the apoptotic functions of cytochrome c reveals a differential requirement for cytochrome c and Apaf-1 in apoptosis. Cell. 121:579–591.
   PubMed Web of Science ®Google Scholar
• Hetz C, Vitte PA, Bombrun A, Rostovtseva TK, Montessuit S, Hiver A, Schwarz MK, Church DJ, Korsmeyer SJ, Martinou JC, et al. 2005. Bax channel inhibitors prevent mitochondrion-mediated apoptosis and protect neurons in a model of global brain ischemia. J Bio Chem. 280:42960–42970.
   PubMed Web of Science ®Google Scholar
• Ji HJ, Wang DM, Hu JF, Sun MN, Li G, Li ZP, Wu DH, Liu G, Chen NH. 2014. IMM-H004, a novel courmarin derivative, protects against oxygen-and glucose-deprivation/restoration-induced apoptosis in PC12 cells. Eur J Pharmacol. 723:259–266.
   PubMed Web of Science ®Google Scholar
• Koshkin V, Greenberg ML. 2002. Cardiolipin prevents rate-dependent uncoupling and provides osmotic stability in yeast mitochondria. Biochem J. 364:317–322.
   PubMed Web of Science ®Google Scholar
• Liang J, Yu Y, Wang B, Lu B, Zhang J, Zhang H, Ge P. 2013. Ginsenoside Rb1 attenuates oxygen-glucose deprivation-induced apoptosis in SH-SY5Y cells via protection of mitochondria and inhibition of AIF and cytochrome c release. Molecules. 18:12777–12792.
   PubMed Web of Science ®Google Scholar
• Lipinski B. 2019. Redox-active selenium in health and disease: a conceptual review. Mini-Rev Med Chem. 19:720–726.
   PubMed Web of Science ®Google Scholar
• Liu F, McCullough LD. 2014. The middle cerebral artery occlusion model of transient focal cerebral ischemia. Methods Mol Biol. 1135:81–93.
   PubMedGoogle Scholar
• Liu X, Zhu X, Chen M, Ge Q, Shen Y, Pan S. 2016. Resveratrol protects PC12 cells against OGD/R-induced apoptosis via the mitochondrial-mediated signaling pathway. Acta Biochim Biophys Sin. 48(4):342–353.
   Google Scholar
• Martin LJ, Adams NA, Pan Y, Price A, Wong M. 2011. The mitochondrial permeability transition pore regulates nitric oxide-mediated apoptosis of neurons induced by target deprivation. J Neurosci. 31:359–370.
   PubMed Web of Science ®Google Scholar
• McIlwain DR, Berger T, Mak TW. 2013. Caspase functions in cell death and disease. Cold Spring Harb Perspect Biol. 5:a008656.
   PubMed Web of Science ®Google Scholar
• Milanlioglu A, Aslan M, Ozkol H, Cilingir V, Nuri Aydin M, Karadas S. 2016. Serum antioxidant enzymes activities and oxidative stress levels in patients with acute ischemic stroke: influence on neurological status and outcome. Wien Klin Wochenschr. 128(5–6):169–174.
   PubMed Web of Science ®Google Scholar
• Moro MA, Almeida A, Bolanos JP, Lizasoain I. 2005. Mitochondrial respiratory chain and free radical generation in stroke. Free Radical Bio Med. 39(10):1291–1304.
   PubMed Web of Science ®Google Scholar
• Naziroglu M, Senol N, Ghazizadeh V, Yuruker V. 2014. Neuroprotection induced by N-acetylcysteine and selenium against traumatic brain injury-induced apoptosis and calcium entry in hippocampus of rat. Cell Mol Neurobiol. 34:895–903.
   PubMed Web of Science ®Google Scholar
• Petito CK, Feldmann E, Pulsinelli WA, Plum F. 1987. Delayed hippocampal damage in humans following cardiorespiratory arrest. Neurology. 37:1281–1286.
   PubMed Web of Science ®Google Scholar
• Powers WJ, Rabinstein AA, Ackerson T, Adeoye OM, Bambakidis NC, Becker K, Biller J, Brown M, Demaerschalk BM, Hoh B, et al. 2018. 2018 guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 49:e46–e110.
   PubMed Web of Science ®Google Scholar
• Rodrigo R, Fernandez-Gajardo R, Gutierrez R, Matamala JM, Carrasco R, Miranda-Merchak A, Feuerhake W. 2013. Oxidative stress and pathophysiology of ischemic stroke: novel therapeutic opportunities. CNS Neurol Disord Drug Targets. 12:698–714.
   PubMed Web of Science ®Google Scholar
• Shimizu S, Narita M, Tsujimoto Y. 1999. Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature. 399:483–487.
   PubMed Web of Science ®Google Scholar
• Spat A, Szanda G. 2017. The role of mitochondria in the activation/maintenance of SOCE: store-operated Ca2+ entry and mitochondria. Adv Exp Med Biol. 993:257–275.
   PubMed Web of Science ®Google Scholar
• Sun JY, Hou YJ, Fu XY, Fu XT, Ma JK, Yang MF, Sun BL, Fan CD, Oh J. 2018. Selenium-containing protein from selenium-enriched Spirulina platensis attenuates cisplatin-induced apoptosis in MC3T3-E1 mouse preosteoblast by inhibiting mitochondrial dysfunction and ROS-mediated oxidative damage. Front Physiol. 9:1907.
   PubMed Web of Science ®Google Scholar
• Toledo FD, Perez LM, Basiglio CL, Ochoa JE, Sanchez Pozzi EJ, Roma MG. 2014. The Ca2+-calmodulin-Ca2+/calmodulin-dependent protein kinase II signaling pathway is involved in oxidative stress-induced mitochondrial permeability transition and apoptosis in isolated rat hepatocytes. Arch Toxicol. 88:1695–1709.
   PubMed Web of Science ®Google Scholar
• Wang XJ, Wang MH, Fu XT, Hou YJ, Chen W, Tian DC, Bai SY, Fu XY. 2018. Selenocysteine antagonizes oxygen glucose deprivation-induced damage to hippocampal neurons. Neural Regen Res. 13:1433–1439.
   PubMed Web of Science ®Google Scholar
• Wang Y, Zhang Y, Yang L, Yuan J, Jia J, Yang S. 2019. SOD2 mediates curcumin-induced protection against oxygen-glucose deprivation/peoxygenation injury in HT22 Cells. Evid-Based Compl Alt eCAM. 2019:1–14.
   Web of Science ®Google Scholar
• Yang E, Zha J, Jockel J, Boise LH, Thompson CB, Korsmeyer SJ. 1995. Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death. Cell. 80:285–291.
   PubMed Web of Science ®Google Scholar
• Yang JL, Mukda S, Chen SD. 2018. Diverse roles of mitochondria in ischemic stroke. Redox Biol. 16:263–275.
   PubMed Web of Science ®Google Scholar
• Yu Q, Wang B, Zhao T, Zhang X, Tao L, Shi J, Sun X, Ding Q. 2017. NaHS protects against the impairments induced by oxygen-glucose deprivation in different ages of primary hippocampal neurons. Front Cell Neurosci. 11:67.
   PubMed Web of Science ®Google Scholar
• Zhang H, Chen T, Jiang J, Wong YS, Yang F, Zheng W. 2011. Selenium-containing allophycocyanin purified from selenium-enriched Spirulina platensis attenuates AAPH-induced oxidative stress in human erythrocytes through inhibition of ROS generation. J Agr Food Chem. 59:8683–8690.
   PubMed Web of Science ®Google Scholar
• Zheng C, Liu T, Liu H, Wang J. 2020. BCL-2 family proteins in apoptosis and its regulation. Curr Protein Pept Sci. 21:799–806.
   PubMed Web of Science ®Google Scholar
• Zhou D, Zhuang J, Wang Y, Zhao D, Zhao L, Zhu S, Pu J, Yin M, Zhang H, Wang Z, et al. 2019. Propofol alleviates DNA damage induced by oxygen glucose deprivation and reperfusion via FoxO1 nuclear translocation in H9c2 cells. Front Physiol. 10:223.
   PubMed Web of Science ®Google Scholar
• Zhu YG, Chen XC, Chen ZZ, Zeng YQ, Shi GB, Su YH, Peng X. 2004. Curcumin protects mitochondria from oxidative damage and attenuates apoptosis in cortical neurons. Acta Pharmacol Sin. 25:1606–1612.
   PubMed Web of Science ®Google Scholar
• Zitnanova I, Siarnik P, Kollar B, Chomova M, Pazderova P, Andrezalova L, Jezovicova M, Konarikova K, Laubertova L, Krivosikova Z, et al. 2016. Oxidative stress markers and their dynamic changes in patients after acute ischemic stroke. Oxid Med Cell Longev. 2016:9761697.
   PubMed Web of Science ®Google Scholar
• Zorov DB, Juhaszova M, Sollott SJ. 2014. Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release. Physiol Rev. 94:909–950.
   PubMed Web of Science ®Google Scholar