2,084
Views
11
CrossRef citations to date
0
Altmetric
Research Article

Clinacanthus nutans attenuates atherosclerosis progression in rats with type 2 diabetes by reducing vascular oxidative stress and inflammation

ORCID Icon, ORCID Icon, ORCID Icon & ORCID Icon
Pages 1430-1438 | Received 22 Feb 2021, Accepted 26 Sep 2021, Published online: 25 Oct 2021

References

  • Abbasnezhad A, Niazmand S, Mahmoudabady M, Rezaee SA, Soukhtanloo M, Mosallanejad R, Hayatdavoudi P. 2019. Nigella sativa L. seed regulated eNOS, VCAM-1, and LOX-1 genes expression and improved vasoreactivity in aorta of diabetic rat. J Ethnopharmacol. 228:142–147.
  • Abdul Rahim MH, Zakaria ZA, Mohd Sani MH, Omar MH, Yakob Y, Cheema MS, Ching SM, Ahmad Z, Abdul Kadir A. 2016. Methanolic extract of Clinacanthus nutans exerts antinociceptive activity via the opioid/nitric oxide-mediated, but CGMP-independent, pathways. Evid Based Complement Alternat Med. 2016:1–11.
  • Alam A, Ferdosh S, Ghafoor K, Hakim A, Juraimi AS, Khatib A, Sarker ZI. 2016. Clinacanthus nutans: a review of the medicinal uses, pharmacology and phytochemistry. Asian Pac J Trop Med. 9(4):402–409.
  • Azemi AK, Mokhtar SS, Low JH, Sharif SET, Rasool AHG. 2020. Model for type 2 diabetes exhibits changes in vascular function and structure due to vascular oxidative stress and inflammation. Biotech Histochem. 22:1–9.
  • Azemi AK, Mokhtar SS, Rasool AHG. 2020. Clinacanthus nutans leaves extract reverts endothelial dysfunction in type 2 diabetes rats by improving protein expression of eNOS. Oxid Med Cell Longev. 2020:7572892.
  • Bao L, Li J, Zha D, Zhang L, Gao P, Yao T, Wu X. 2018. Chlorogenic acid prevents diabetic nephropathy by inhibiting oxidative stress and inflammation through modulation of the Nrf2/HO-1 and NF-ĸB pathways. Int Immunopharmacol. 54:245–253.
  • Birben E, Sahiner UM, Sackesen C, Erzurum S, Kalayci O. 2012. Oxidative stress and antioxidant defense. World Allergy Organ J. 5(1):9–19.
  • Chao CY, Mong MC, Chan KC, Yin MC. 2010. Anti-glycative and anti-inflammatory effects of caffeic acid and ellagic acid in kidney of diabetic mice. Mol Nutr Food Res. 54(3):388–395.
  • Chavez-Santoscoy RA, Gutierrez-Uribe JA, Granados O, Torre-Villalvazo I, Serna-Saldivar SO, Torres N, Palacios-González B, Tovar AR. 2014. Flavonoids and saponins extracted from black bean (Phaseolus vulgaris L.) seed coats modulate lipid metabolism and biliary cholesterol secretion in C57BL/6 mice. Br J Nutr. 112(6):886–899.
  • Chen L, Wang WY, Wang YP. 2009. Inhibitory effects of lithospermic acid on proliferation and migration of rat vascular smooth muscle cells. Acta Pharmacol Sin. 30(9):1245–1252.
  • Chikezie OD, Meludu SC, Ogbu ISI, Egejuru BN, Ude T, Ekuma-Ogbonnia O. 2020. Blood lipids and its atherogenic indices in alloxan-induced diabetic male rats. AJARR. 9:25–33.
  • Chung DJ, Wu YL, Yang MY, Chan KC, Lee HJ, Wang CJ. 2020. Nelumbo nucifera leaf polyphenol extract and gallic acid inhibit TNF-α-induced vascular smooth muscle cell proliferation and migration involving the regulation of miR-21, miR-143 and miR-145. Food Funct. 11(10):8602–8611.
  • Cure E, Cumhur Cure M. 2020. Comment on “usefulness of atherogenic indices and Ca-LDL level to predict subclinical atherosclerosis in patients with psoriatic arthritis?” Adv Rheumatol. 60(1):23.
  • Cure E, Icli A, Uslu AU, Sakiz D, Cure MC, Baykara RA, Yavuz F, Arslan S, Kucuk A. 2018. Atherogenic index of plasma: a useful marker for subclinical atherosclerosis in ankylosing spondylitis: AIP associate with cIMT in AS. Clin Rheumatol. 37(5):1273–1280.
  • Eleazu CO, Eleazu KC, Chukwuma SC, Okoronkwo J, Emelike CU. 2014. Effect of livingstonepotato (Plectranthus esculenthus N.E.Br) on hyperglycemia, antioxidant activity, and lipid metabolism of streptozotocin induced diabetic rats. Toxicol Rep. 1:674–681.
  • Gabás-Rivera C, Barranquero C, Martínez-Beamonte R, Navarro MA, Surra JC, Osada J. 2014. Dietary squalene increases high density lipoprotein-cholesterol and paraoxonase 1 and decreases oxidative stress in mice. PLOS One. 9(8):e104224.
  • Harini R, Pugalendi KV. 2010. Antioxidant and antihyperlipidaemic activity of protocatechuic acid on streptozotocin-diabetic rats. Redox Rep. 15(2):71–80.
  • International Diabetes Federation. 2019. IDF Diabetes Atlas. 9th ed. Brussels, Belgium: Atlas de La Diabetes de La FID.
  • Ishak NA, Ismail M, Hamid M, Ahmad Z, Ghafar SAA. 2013. Antidiabetic and hypolipidemic activities of Curculigo latifolia fruit: root extract in high fat fed diet and low dose STZ induced diabetic rats. Evid Based Complement Alternat Med. 2013:1–12.
  • Ismail Suhaimy NW, Azmi AKN, Mohtarrudin N, Omar MH, Tohid SFM, Cheema SM, Teh LK, Salleh MZ, Zakaria ZA. 2017. Semipurified ethyl acetate partition of methanolic extract of Melastoma malabathricum leaves exerts gastroprotective activity partly via its antioxidant-antisecretory-anti-inflammatory action and synergistic action of several flavonoid-based compounds. Oxid Med Cell Longev. 2017:6542631.
  • Jia Y, Xu B, Xu J. 2017. Effects of type 2 diabetes mellitus on the pharmacokinetics of berberine in rats. Pharm Biol. 55(1):510–515.
  • Jiang Y, Dai M, Nie WJ, Yang XR, Zeng XC. 2017. Effects of the ethanol extract of black mulberry (Morus nigra L.) fruit on experimental atherosclerosis in rats. J Ethnopharmacol. 200:228–235.
  • Jin ZG, Melaragno MG, Liao DF, Yan C, Haendeler J, Suh YA, Lambeth JD, Berk BC. 2000. Cyclophilin A is a secreted growth factor induced by oxidative stress. Circ Res. 87(9):789–796.
  • Katsube T, Tabata H, Ohta Y, Yamasaki Y, Anuurad E, Shiwaku K, Yamane Y. 2004. Screening for antioxidant activity in edible plant products: comparison of low-density lipoprotein oxidation assay, DPPH radical scavenging assay, and Folin-Ciocalteu assay. J Agric Food Chem. 52(8):2391–2396.
  • Kazemi T, Hajihosseini M, Moossavi M, Hemmati M, Ziaee M. 2018. Cardiovascular risk factors and atherogenic indices in an Iranian population: Birjand east of Iran. Clin Med Insights Cardiol. 12:1179546818759286.
  • Li P-G, Xu J-W, Ikeda K, Kobayakawa A, Kayano Y, Mitani T, Ikami T, Yamori Y. 2005. Caffeic acid inhibits vascular smooth muscle cell proliferation induced by angiotensin II in stroke-prone spontaneously hypertensive rats. Hypertens Res. 28(4):369–377.
  • Lim SM, Goh YM, Mohtarrudin N, Loh SP. 2016. Germinated brown rice ameliorates obesity in high-fat diet induced obese rats. BMC Complement Altern Med. 16:140.
  • Lin CY, Huang CS, Huang CY, Yin MC. 2009. Anticoagulatory, antiinflammatory, and antioxidative effects of protocatechuic acid in diabetic mice. J Agric Food Chem. 57(15):6661–6667.
  • Lin MC, Ou TT, Chang CH, Chan KC, Wang CJ. 2015. Protocatechuic acid inhibits oleic acid-induced vascular smooth muscle cell proliferation through activation of AMP-activated protein kinase and cell cycle arrest in G0/G1 phase. J Agric Food Chem. 63(1):235–241.
  • Mai CW, Yap KS, Kho MT, Ismail NH, Yusoff K, Shaari K, Chin SY, Lim ES. 2016. Mechanisms underlying the anti-inflammatory effects of Clinacanthus nutans Lindau extracts: inhibition of cytokine production and toll-like receptor-4 activation. Front Pharmacol. 7:7.
  • Mokhtar SS, Vanhoutte PM, Leung SW, Suppian R, Yusof MI, Rasool AH. 2016. Reduced nitric oxide-mediated relaxation and endothelial nitric oxide synthase expression in the tail arteries of streptozotocin-induced diabetic rats. Eur J Pharmacol. 773:78–84.
  • Nelson JR, Wani O, May HT, Budoff M. 2017. Potential benefits of eicosapentaenoic acid on atherosclerotic plaques. Vascul Pharmacol. 91:1–9.
  • Nguyen LTH, Muktabar A, Tang J, Wong YS, Thaxton CS, Venkatraman SS, Ng KW. 2018. The potential of fluocinolone acetonide to mitigate inflammation and lipid accumulation in 2D and 3D foam cell cultures. Biomed Res Int. 2018:3739251.
  • Niemann-Jönsson A, Dimayuga P, Jovinge S, Calara F, Ares MP, Fredrikson GN, Nilsson J. 2000. Accumulation of LDL in rat arteries is associated with activation of tumor necrosis factor-alpha expression. Arterioscler Thromb Vasc Biol. 20(10):2205–2211.
  • Okutan H, Ozcelik N, Yilmaz HR, Uz E. 2005. Effects of caffeic acid phenethyl ester on lipid peroxidation and antioxidant enzymes in diabetic rat heart. Clin Biochem. 38(2):191–196.
  • Othman ZA, Ghazali WSW, Noordin L, Yusof NAM, Mohamed M. 2019. Phenolic compounds and the anti-atherogenic effect of bee bread in high-fat diet-induced obese rats. Antioxidants. 9(1):33.
  • Oztürk Z, Gurpinar T, Vural K, Boyacıoglu S, Korkmaz M, Var A. 2015. Effects of selenium on endothelial dysfunction and metabolic profile in low dose streptozotocin induced diabetic rats fed a high fat diet. Biotech Histochem. 90(7):506–515.
  • Persson J, Nilsson J, Lindholm MW. 2006. Cytokine response to lipoprotein lipid loading in human monocyte-derived macrophages. Lipids Health Dis. 5:17.
  • Sarega N, Imam MU, Ooi DJ, Chan KW, Md Esa N, Zawawi N, Ismail M. 2016. Phenolic rich extract from Clinacanthus nutans attenuates hyperlipidemia-associated oxidative stress in rats. Oxid Med Cell Longev. 2016:4137908.
  • Sharma P, Jha AB, Dubey RS, Pessarakli M. 2012. Reactive oxygen species, oxidative damage, and antioxidative defense mechanism in plants under stressful conditions. J Bot. 2012:217037.
  • Sonne DP, Knop FK. 2015. Comment on Xu et al. effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes. Diabetes Care. 38(12):e215.
  • Sun MY, Zhang M, Chen SL, Zhang SP, Guo CY, Wang JS, Liu X, Miao Y, Yin HJ. 2018. The influence of hyperlipidemia on endothelial function of FPN1 Tek-Cre mice and the intervention effect of tetramethylpyrazine. Cell Physiol Biochem. 47(1):119–128.
  • Umar Imam M, Ismail M, George A, Chinnappan SM, Yusof A. 2019. Aqueous leaf extract of Clinacanthus nutans improved metabolic indices and sarbitol-related complications in type II diabetic rats (T2D). Food Sci Nutr. 7(4):1482–1493.
  • Wan CW, Wong CN, Pin WK, Wong MH, Kwok CY, Chan RY, Yu PH, Chan SW. 2013. Chlorogenic acid exhibits cholesterol lowering and fatty liver attenuating properties by up-regulating the gene expression of PPAR-α in hypercholesterolemic rats induced with a high-cholesterol diet. Phytother Res. 27(4):545–551.
  • Wihastuti TA, Heriansyah T, Hanifa H, Andarini S, Sholichah Z, Sulfia YH, Adam AA, Refialdinata J, Lutfiana NC. 2018. Darapladib inhibits atherosclerosis development in type 2 diabetes mellitus Sprague-Dawley rat model. Endocr Regul. 52(2):69–75.
  • Wu C, Luan H, Zhang X, Wang S, Zhang X, Sun X, Guo P. 2014. Chlorogenic acid protects against atherosclerosis in ApoE–/– mice and promotes cholesterol efflux from RAW264.7 macrophages. PLOS One. 9(9):e95452.
  • Wu YT, Chen L, Tan ZB, Fan HJ, Xie LP, Zhang WT, Chen HM, Li J, Liu B, Zhou YC. 2018. Luteolin inhibits vascular smooth muscle cell proliferation and migration by inhibiting TGFBR1 signaling. Front Pharmacol. 9:1059.
  • Yimin Furumaki H, Matsuoka S, Sakurai T, Kohanawa M, Zhao S, Kuge Y, Tamaki N, Chiba H. 2012. A novel murine model for non-alcoholic steatohepatitis developed by combination of a high-fat diet and oxidized low-density lipoprotein. Lab Invest. 92:265–281.
  • Yuan T, Yang T, Chen H, Fu D, Hu Y, Wang J, Yuan Q, Yu H, Xu W, Xie X. 2019. New insights into oxidative stress and inflammation during diabetes mellitus-accelerated atherosclerosis. Redox Biol. 20:247–260.
  • Zhu J, Wang CG, Xu YG. 2011. Lycopene attenuates endothelial dysfunction in streptozotocin-induced diabetic rats by reducing oxidative stress. Pharm Biol. 49(11):1144–1149.