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Research Article

Pharmacokinetic interaction between rhynchopylline and pellodendrine via CYP450 enzymes and P-gp

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Pages 1549-1553 | Received 26 Jul 2021, Accepted 26 Oct 2021, Published online: 10 Nov 2021

References

  • Chen L, You W, Chen D, Cai Y, Wang X, Wen C, Wu B. 2018. Pharmacokinetic interaction study of ketamine and rhynchophylline in rat plasma by ultra-performance liquid chromatography tandem mass spectrometry. Biomed Res Int. 2018:6562309.
  • Chen M, Geng D, Yang X, Liu X, Liu S, Ding P, Pang Y, Du M, Hu X, Wang R. 2020. In vitro nephrotoxicity induced by herb-herb interaction between Radix Glycyrrhizae and Radix Euphorbiae Pekinensis. Oxid Med Cell Longev. 2020:6894751.
  • Elmeliegy M, Vourvahis M, Guo C, Wang DD. 2020. Effect of P-glycoprotein (P-gp) inducers on exposure of P-gp substrates: review of clinical drug-drug interaction studies. Clin Pharmacokinet. 59(6):699–714.
  • Fugh-Berman A. 2000. Herb-drug interactions. Lancet. 355(9198):134–138.
  • Hattori T, Furuta K, Hayashi K, Nagamatsu T, Ito M, Suzuki Y. 1992. Studies on the antinephritic effects of plant components (6): antinephritic effects and mechanisms of phellodendrine (OB-5) on crescentic-type anti-GBM nephritis in rats (2). Jpn J Pharmacol. 60(3):187–195.
  • Hongyan L, Mengjiao Z, Chunyan W, Yaruo H. 2019. Rhynchophylline attenuates neurotoxicity in tourette syndrome rats. Neurotox Res. 36(4):679–687.
  • Jiang N, Zhang M, Meng X, Sun B. 2020. Effects of curcumin on the pharmacokinetics of amlodipine in rats and its potential mechanism. Pharm Biol. 58(1):465–468.
  • Li J, Wen H, Gao Z. 2020. In vitro inhibitory effects of phellodendrine on human liver cytochrome P450 enzymes. Xenobiotica. 50(2):231–236.
  • McKeand W, Baird-Bellaire S, Ermer J, Patat A. 2018. Pharmacokinetic drug interaction study of bazedoxifene and ibuprofen. Clin Pharmacol Drug Dev. 7(4):358–364.
  • Mori H, Fuchigami M, Inoue N, Nagai H, Koda A, Nishioka I, Meguro K. 1995. Principle of the bark of Phellodendron amurense to suppress the cellular immune response: effect of phellodendrine on cellular and humoral immune responses. Planta Med. 61(1):45–49.
  • Ramanathan MR, Penzak SR. 2017. Pharmacokinetic drug interactions with Panax ginseng. Eur J Drug Metab Pharmacokinet. 42(4):545–557.
  • Shellard EJ, Lala PK. 1978. The alkaloids of Mitragyna rubrostipulata (Schum.) Havil. Planta Med. 33(1):63–69.
  • Su S, Wang X, Xi X, Zhu L, Chen Q, Zhang H, Qin Y, Yang B, Che N, Cao H, et al. 2021. Phellodendrine promotes autophagy by regulating the AMPK/mTOR pathway and treats ulcerative colitis. J Cell Mol Med. 25(12):5707–5720.
  • Thu PM, Zheng ZG, Zhou YP, Wang YY, Zhang X, Jing D, Cheng HM, Li J, Li P, Xu X. 2019. Phellodendrine chloride suppresses proliferation of KRAS mutated pancreatic cancer cells through inhibition of nutrients uptake via macropinocytosis. Eur J Pharmacol. 850:23–34.
  • Wang W, Ma CM, Hattori M. 2010. Metabolism and pharmacokinetics of rhynchophylline in rats. Biol Pharm Bull. 33(4):669–676.
  • Xu R, Wang J, Xu J, Song X, Huang H, Feng Y, Fu C. 2020. Rhynchophylline loaded-mPEG-PLGA nanoparticles coated with Tween-80 for preliminary study in Alzheimer's disease. Int J Nanomedicine. 15:1149–1160.
  • Yang L, Meng X, Yu X, Kuang H. 2017. Simultaneous determination of anemoside B4, phellodendrine, berberine, palmatine, obakunone, esculin, esculetin in rat plasma by UPLC-ESI-MS/MS and its application to a comparative pharmacokinetic study in normal and ulcerative colitis rats. J Pharm Biomed Anal. 134:43–52.