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Research Article

In vitro-in vivo availability of metformin hydrochloride-PLGA nanoparticles in diabetic rats in a periodontal disease experimental model

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Pages 1574-1582 | Received 02 Jul 2021, Accepted 29 Oct 2021, Published online: 22 Nov 2021

References

  • Agência Nacional de Vigilância Sanitária (ANVISA) 2012. Requisitos mínimos para a validação de métodos bioanalíticos empregados em estudos com fins de registro e pós-registro de medicamentos [Minimum requirements for validation of bioanalytical methods used in studies for drug registration and post-registration purposes]. Resolution. 27:93.
  • Bhujbal S, Dash AK. 2018. Metformin-loaded hyaluronic acid nanostructure for oral delivery. AAPS PharmSciTech. 19(6):2543–2553.
  • Bobrovnikova-Marjon E, Hurov JB. 2014. Targeting metabolic changes in cancer: novel therapeutic approaches. Annu Rev Med. 65:157–170.
  • Cafferata EA, Alvarez C, Diaz KT, Maureira M, Monasterio G, González FE, Covarrubias C, Vernal R. 2019. Multifunctional nanocarriers for the treatment of periodontitis: Immunomodulatory, antimicrobial, and regenerative strategies. Oral Dis. 25(8):1866–1878.
  • Corremans R, Vervaet BA, D’Haese PC, Neven E, Verhulst A. 2018. Metformin: a candidate drug for renal diseases. IJMS. 20(1):42–56.
  • Fenglin QI, Xiaoqing Z, Shuping L. 2013. A novel method to get methotrexatum/layered double hydroxides intercalation compounds and their release properties. J Phys Chem Solids. 74(8):1101–1108.
  • Foretz M, Guigas B, Viollet B. 2019. Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus. Nat Rev Endocrinol. 15(10):569–589.
  • Gong L, Goswami S, Giacomini KM, Altman RB, Klein TE. 2012. Metformin pathways: pharmacokinetics and pharmacodynamics. Pharmacogenet Genomics. 22(11):820–827.
  • Gundogdu N, Cetin M. 2014. Chitosan-poly (lactide-co-glycolide) (CS-PLGA) nanoparticles containing metformin HCl: preparation and in vitro evaluation. Pak J Pharm Sci. 27(6):1923–1929.
  • Han SY, Choi YH. 2020. Pharmacokinetic interaction between metformin and verapamil in rats: inhibition of the OCT2-mediated renal excretion of metformin by verapamil. Pharmaceutics. 12(5):468–483.
  • Hopfgartner G. 2020. Bioanalytical method validation: How much should we do and how should we document? Anal Bioanal Chem. 412(3):531–532.
  • Kimura N, Masuda S, Tanihara Y, Ueo H, Okuda M, Katsura T, Inui K. 2005. Metformin is a superior substrate for renal organic cation transporter OCT2 rather than hepatic OCT1. Drug Metab Pharmacokinet. 20(5):379–386.
  • Kumar S, Bhanjana G, Verma RK, Dhingra D, Dilbaghi N, Kim KH. 2017. Metformin-loaded alginate nanoparticles as an effective antidiabetic agent for controlled drug release. J Pharm Pharmacol. 69(2):143–150.
  • Lee CH, Hsieh MJ, Chang SH, Lin YH, Liu SJ, Lin TY, Hung KC, Pang JH, Juang JH. 2014. Enhancement of diabetic wound repair using biodegradable nanofibrous metformin-eluting membranes: in vitro and in vivo. ACS Appl Mater Interfaces. 6(6):3979–3986.
  • Mandl HK, Quijano E, Suh HW, Sparago E, Oeck S, Grun M, Glazer PM, Saltzman WM. 2019. Optimizing biodegradable nanoparticle size for tissue-specific delivery. J Control Release. 314:92–101.
  • Mourão SC, da Silva C, Bresolin TM, Serra CH, Porta V. 2010. Dissolution parameters for sodium diclofenac-containing hypromellose matrix tablet. Int J Pharm. 386(1-2):201–207.
  • Murphy C, Pillay V, Choonara YE, Du Toit LC, Ndesendo VM, Chirwa N, Kumar P. 2012. Optimization of a dual mechanism gastrofloatable and gastroadhesive delivery system for narrow absorption window drugs. AAPS Pharm Sci Tech. 13(1):1–15.
  • Patiño-Herrera R, Louvier-Hernández JF, Escamilla-Silva EM, Chaumel J, Escobedo AGP, Pérez E. 2019. Prolonged release of metformin by SiO2 nanoparticles pellets for type II diabetes control. Eur J Pharm Sci. 131:1–8.
  • Pereira A, Brito G, Lima M, Silva Júnior A, Silva E, de Rezende A, Bortolin R, Galvan M, Pirih F, Araújo Júnior R, et al. 2018. Metformin hydrochloride-loaded PLGA nanoparticle in periodontal disease experimental model using diabetic rats. IJMS. 19(11):3488–3504.
  • Sharma A, Madhunapantula SV, Robertson GP. 2012. Toxicological considerations when creating nanoparticle-based drugs and drug delivery systems. Expert Opin Drug Metab Toxicol. 8(1):47–69.
  • Shibata M, Toyoshima J, Kaneko Y, Oda K, Nishimura T. 2020. A drug-drug interaction study to evaluate the impact of peficitinib on OCT1- and MATE1-mediated transport of metformin in healthy volunteers. Eur J Clin Pharmacol. 76(8):1135–1141.
  • Taghipour YD, Bahramsoltani R, Marques AM, Naseri R, Rahimi R, Haratipour P, Iranpanah A, Panah AI, Farzaei MH, Abdollahi M. 2018. A systematic review of nano formulation of natural products for the treatment of inflammatory bowel disease: drug delivery and pharmacological targets. Daru. 26(2):229–239.
  • The International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) 2019. Bioanalytical Method Validation M10; [accessed 2021 Apr 30]. http://ema.europa.eu/en/documents/scientific-guideline/draft-ich-guideline-m10-bioanalytical-method-validation-step-2b_en.pdf
  • Wang J, Chin D, Poon C, Mancino V, Pham J, Li H, Ho PY, Hallows KR, Chung EJ. 2021. Oral delivery of metformin by chitosan nanoparticles for polycystic kidney disease. J Control Release. 329:1198–1209.
  • Wook Huh H, Na YG, Kang H, Kim M, Han M, Mai Anh Pham T, Lee H, Baek JS, Lee HK, Cho CW. 2021. Novel self-floating tablet for enhanced oral bioavailability of metformin based on cellulose. Int J Pharm. 592:120113.
  • Zhou J, Patel TR, Fu M, Bertram JP, Saltzman WM. 2012. Octa-functional PLGA nanoparticles for targeted and efficient siRNA delivery to tumors. Biomaterials. 33(2):583–591.