Advanced search
Publication Cover
Modern Rheumatology Volume 31, 2021 - Issue 1
Journal homepage
406
Views
6
CrossRef citations to date
0
Altmetric
Rheumatoid Arthritis

Efficacy and safety of tacrolimus in patients with rheumatoid arthritis – A systematic review and meta-analysis

Yuko Kanekoa Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, JapanCorrespondence[email protected]
View further author information
,
Yutaka Kawahitob Inflammation and Immunology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, JapanView further author information
,
Masayo Kojimac Department of Public Health, Graduate School of Medical Sciences, Nagoya City University, Nagoya, JapanView further author information
,
Takeo Nakayamad Department of Health Informatics, Kyoto University School of Public Health, Kyoto, JapanView further author information
,
Shintaro Hiratae The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan;f Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, JapanView further author information
,
Mitsumasa Kishimotog Immuno-Rheumatology Center, St Luke’s International Hospital, Tokyo JapanView further author information
,
Hirahito Endoh Division of Rheumatology, Department of Internal Medicine, School of Medicine, Toho University Tokyo, Tokyo, JapanView further author information
,
Yohei Setoi Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, JapanView further author information
,
Hiromu Itoj Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, Kyoto, JapanView further author information
,
Keiichiro Nishidak Department of Orthopaedic Surgery, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Okayama, JapanView further author information
,
Isao Matsushital Department of Orthopaedic Surgery Faculty of Medicine, University of Toyama, Toyama, JapanView further author information
,
Toshihisa Kojimam Department of Orthopedic Surgery, Nagoya University Hospital, Nagoya, JapanView further author information
,
Naoyuki Kamatanii Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, JapanView further author information
,
Kiichiro Tsutanin Faculty of Health Sciences, Tokyo Ariake University of Medical and Health Sciences, Tokyo, JapanView further author information
,
Ataru Igarashio Department of Drug Policy and Management, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, JapanView further author information
,
Mieko Hasegawap The Japan Rheumatism Friendship Association, JapanView further author information
,
Nobuyuki Miyasakaq Tokyo Medical and Dental University, Tokyo, JapanView further author information
&
Hisashi Yamanakai Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, JapanView further author information
 show all
Pages 61-69 | Received 30 Aug 2019, Accepted 16 Jan 2020, Published online: 30 Jan 2020

References

  • Smolen JS, Landewé R, Bijlsma J, Burmester G, Chatzidionysiou K, Dougados M, et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update. Ann Rheum Dis. 2017;76(6):960–77.
  • Miyata S, Ohkubo Y, Mutoh S. A review of the action of tacrolimus (FK506) on experimental models of rheumatoid arthritis. Inflamm Res. 2005;54(1):1–9.
  • Wiederrecht G, Lam E, Hung S, Martin M, Sigal N. The mechanism of action of FK-506 and cyclosporin A. Ann N Y Acad Sci. 2006;696(1):9–19.
  • Lee YH, Woo JH, Choi SJ, Ji JD, Bae SC, Song GG. Tacrolimus for the treatment of active rheumatoid arthritis: a systematic review and meta-analysis of randomized controlled trials. Scand J Rheumatol. 2010;39(4):271–8.
  • Sharrar RG, Dieck GS. Monitoring product safety in the postmarketing environment. Ther Adv Drug Saf. 2013;4(5):211–9.
  • Guyatt G, Oxman AD, Akl E, Kunz R, Vist G, Brozek J. et al. GRADE guidelines 1. Introduction-GRADE evidence profiles and summary of findings tables. J Clin Epidemiol 2011;64(4):383–394.
  • GRADE Working group. Available from: http://www.gradeworkinggroup.org/index.htm
  • Arnett FC1, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 1988;31(3):315–24.
  • Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, Bingham CO 3rd, et al. 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Ann Rheum Dis. 2010;69(9):1580–8.
  • Higgins JPT, Altman DG, Sterne JAC, On behalf of the Cochrane Statistical Methods Group and the Cochrane Bias Methods Group. ‘Assessing risk of bias in included studies,’ in Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0, J. P. T. Higgins and S. Green, Eds., Chapter 8, The Cochrane Collaboration, 2011. Available from: http://handbook.cochrane.org/.
  • Schunemann H, Brozek J, Oxman A. GRADE Handbook for Grading Quality of Evidence and Strength of Recommendation, version 3.2, The GRADE Working Group, 2009. Available from: http://www.cc-ims.net/gradepro.
  • Website of GRADE PRO. Available from: https://gradepro.org/ https://community.cochrane.org/help/tools-and-software/gradepro-gdt.
  • Furst DE, Saag K, Fleischmann MR, Sherrer Y, Block JA, Schnitzer T, et al. Efficacy of tacrolimus in rheumatoid arthritis patients who have been treated unsuccessfully with methotrexate: a six-month, double-blind, randomized, dose-ranging study. Arthritis Rheum. 2002;46(8):2020–8.
  • Yocum DE, Furst DE, Kaine JL, Baldassare AR, Stevenson JT, Borton MA, et al. Efficacy and safety of tacrolimus in patients with rheumatoid arthritis: a double-blind trial. Arthritis Rheum. 2003;48(12):3328–37.
  • Kondo H, Abe T, Hashimoto H, Uchida S, Irimajiri S, Hara M, et al.. Efficacy and safety of tacrolimus (FK506) in treatment of rheumatoid arthritis: a randomized, double blind, placebo controlled dose-finding study. J Rheumatol. 2004;31:243–51.
  • Kawai S, Hashimoto H, Kondo H, Murayama T, Kiuchi T, Abe T. Comparison of tacrolimus and mizoribine in a randomized, double-blind controlled study in patients with rheumatoid arthritis. J Rheumatol 2006;33(11):2153–61.
  • Kawai S, Takeuchi T, Yamamoto K, Tanaka Y, Miyasaka N. Efficacy and safety of additional use of tacrolimus in patients with early rheumatoid arthritis with inadequate response to DMARDs-a multicenter, double-blind, parallel-group trial. Mod Rheumatol. 2011;21(5):458–68.
  • Tanaka Y, Kawai S, Takeuchi T, Yamamoto K, Miyasaka N. Prevention of joint destruction by tacrolimus in patients with early rheumatoid arthritis: a post hoc analysis of a double-blind, randomized, placebo-controlled study. Mod Rheumatol. 2013;23(6):1045–52.
  • Takeuchi T, Ishida K, Shiraki K, Yoshiyasu T. Safety and effectiveness of tacrolimus add-on therapy for rheumatoid arthritis patients without an adequate response to biological disease-modifying anti-rheumatic drugs (DMARDs): post-marketing surveillance in Japan. Mod Rheumatol. 2018;28(1):48–57.
  • Böttiger Y, Brattström C, Tydén G, Säwe J, Groth CG. Tacrolimus whole blood concentrations correlate closely to side-effects in renal transplant recipients. Br J Clin Pharmacol 1999;48:445–8.
  • Kremer JM, Habros JS, Kolba KS, Kaine JL, Borton MA, Mengle-Gaw LJ, et al. Tacrolimus-Methotrexate Rheumatoid Arthritis Study Group. Tacrolimus in rheumatoid arthritis patients receiving concomitant methotrexate: a six-month, open-label study. Arthritis Rheum. 2003;48(10):2763–8.
  • Suzuki K, Kameda H, Amano K, Nagasawa H, Takei H, Sekiguchi N, et al. Single center prospective study of tacrolimus efficacy and safety in treatment of rheumatoid arthritis. Rheumatol Int. 2009;29(4):431–6.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.