115
Views
7
CrossRef citations to date
0
Altmetric
Connective tissue diseases and related disorders

Prevention of bone loss and improvement of pain-related behavior in hind limb-unloaded mice by administration of teriparatide and bisphosphonate

, , , , , & show all
Pages 733-742 | Received 30 Jan 2020, Accepted 08 Jun 2020, Published online: 10 Jul 2020

References

  • NIH Consensus Development Panel on Osteoporosis Prevention, Diagnosis, and Therapy. Osteoporosis prevention, diagnosis, and therapy. JAMA. 2001;14(285):785–95.
  • Silverman SL, Piziak VK, Chen P, Misurski DA, Wagman RB. Relationship of health related quality of life to prevalent and new or worsening back pain in postmenopausal women with osteoporosis. J Rheumatol. 2005;32(12):2405–9.
  • Salaffi F, Cimmino MA, Malavolta N, Carotti M, Matteo Scendoni DL, et al. The burden of prevalent fractures on health-related quality of life in postmenopausal women with osteoporosis: the IMOF study. J Rheumatol. 2007;34(7):1551–60.
  • Adami S, Maugeri D, Toscano V, Topa G, Carminiti M, Brancati A, et al. Baseline characteristics of the population enrolled in the Italian Observational Study on Severe Osteoporosis (ISSO). Clin Exp Rheumatol. 2011;29(3):477–84.
  • Lloyd SA, Morony SE, Ferguson VL, Simske SJ, Stodieck LS, Warmington KS, et al. Osteoprotegerin is an effective countermeasure for spaceflight-induced bone loss in mice. Bone 2015;81:562–72.
  • Ishijima M, Tsuji K, Rittling SR, Yamashita T, Kurosawa H, Denhardt DT, et al. Resistance to unloading-induced three-dimensional bone loss in osteopontin-deficient mice. J Bone Miner Res. 2002;17(4):661–7.
  • Morey-Holton ER, Globus RK. Hindlimb unloading of growing rats: a model for predicting skeletal changes during space flight. Bone. 1998;22(5):83S–8S.
  • Sakata T, Sakai A, Tsurukami H, Okimoto N, Okazaki Y, Ikeda S, et al. Trabecular bone turnover and bone marrow cell development in tail-suspended mice. J Bone Miner Res. 1999;14(9):1596–604.
  • Sakai A, Nakamura T. Changes in trabecular bone turnover and bone marrow cell development in tail-suspended mice. J Musculoskelet Neuronal Interact. 2001;1(4):387–92.
  • Nakagawa T, Wakabayashi H, Naito Y, Kato S, Miyamura G, Iino T, et al. The effects of bisphosphonate on pain-related behavior and immunohistochemical analyses in hindlimb-unloaded mice. J Orthop Sci. 2018;23(6):1063–9.
  • McClung MR, San Martin J, Miller PD, Civitelli R, Bandeira F, Omizo M, et al. Opposite bone remodeling effects of teriparatide and alendronate in increasing bone mass. Arch Intern Med. 2005;165(15):1762–8.
  • Neer RM, Arnaud CD, Zanchetta JR, Prince R, Gaich GA, Reginster JY, et al. Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis. N Engl J Med. 2001;344(19):1434–41.
  • Kato S, Wakabayashi H, Nakagawa T, Miyamura G, Naito Y, Iino T, et al. Teriparatide improves pain-related behavior and prevents bone loss in ovariectomized mice. J Orthop Surg (Hong Kong). 2020;28(1):2309499019893194
  • Sakai A, Sakata T, Ikeda S, Uchida S, Okazaki R, Norimura T, et al. Intermittent administration of human parathyroid Hormone(1-34) prevents immobilization-related bone loss by regulating bone marrow capacity for bone cells in ddY mice. J Bone Miner Res. 1999;14(10):1691–9.
  • Kaback LA, Soung d. Y, Naik A, Geneau G, Schwarz EM, Rosier RN, et al. Teriparatide (1–34 human PTH) regulation of osterix during fracture repair. J Cell Biochem. 2008;105(1):219–26.
  • Driscoll C, Chanalaris A, Knights C, Ismail H, Sacitharan PK, Gentry C, et al. Nociceptive sensitizers are regulated in damaged joint tissues, including articular cartilage, when osteoarthritic mice display pain behavior. Arthritis Rheumatol. 2016;68(4):857–67.
  • Izumi M, Ikeuchi M, Ji Q, Tani T. Local ASIC3 modulates pain and disease progression in a rat model of osteoarthritis. J Biomed Sci. 2012;19:77.
  • Simske SJ, Broz JJ, Fleet ML, Schmeister TA, Gayles EC, Luttges MW. Contribution of dietary and loading changes to the effects of suspension on mouse femora. J Exp Zool. 1994;269(3):277–85.
  • Moriishi T, Fukuyama R, Ito M, Miyazaki T, Maeno T, Kawai Y, et al. Osteocyte network; a negative regulatory system for bone mass augmented by the induction of Rankl in osteoblasts and Sost in osteocytes at unloading. PLOS One. 2012;7(6):e40143
  • de Castro LF, Lozano D, Portal-Núñez S, Maycas M, De la Fuente M, Caeiro JR, et al. Comparison of the skeletal effects induced by daily administration of PTHrP (1-36) and PTHrP (107-139) to ovariectomized mice. J Cell Physiol. 2012;227(4):1752–60.
  • Lyritis G, Marin F, Barker C, Pfeifer M, Farrerons J, Brixen K, et al. Back pain during different sequential treatment regimens of teriparatide: results from EUROFORS. Curr Med Res Opin. 2010;26(8):1799–807.
  • Nevitt MC, Chen P, Dore RK, Reginster JY, Kiel DP, Zanchetta JR, et al. Reduced risk of back pain following teriparatide treatment: a meta-analysis. Osteoporos Int. 2006;17(2):273–80.
  • Hadji P, Zanchetta JR, Russo L, Recknor CP, Saag KG, McKiernan FE, et al. The effect of teriparatide compared with risedronate on reduction of back pain in postmenopausal women with osteoporotic vertebral fractures. Osteoporos Int. 2012;23(8):2141–50.
  • Compston JE. Skeletal actions of intermittent parathyroid hormone: effects on bone remodelling and structure. Bone 2007;40(6):1447–52.
  • Jia HB, Ma JX, Ma XL, Yu JT, Feng R, Xu LY, et al. Estrogen alone or in combination with parathyroid hormone can decrease vertebral MEF2 and sclerostin expression and increase vertebral bone mass in ovariectomized rats. Osteoporos Int. 2014;25(12):2743–54.
  • Isogai Y, Takao-Kawabata R, Takakura A, Sugimoto E, Nakazono O, Ikegaki I, et al. Early effects of single and low-frequency repeated administration of teriparatide, hPTH(1-34), on bone formation and resorption in ovariectomized rats. Calcif Tissue Int. 2015;97(4):412–20.
  • Dohke T, Iba K, Hanaka M, Kanaya K, Okazaki S, Yamashita T. Teriparatide rapidly improves pain-like behavior in ovariectomized mice in association with the downregulation of inflammatory cytokine expression. J Bone Miner Metab. 2018;36(5):499–507.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.