References
- Ashoub M. R., Biggers J. D., McLaren A., Michie D. The effect of environment on phenotypic variability. Proceedings of the Royal Society of London 1958; 148B: 192–203
- Biggers J. D. Human generation: Fact, foible and fable. Infertility: A comprehensive text, M. Seibel. Appleton-Lange, Norwalk, CT 1989; 551–562
- Biggers J. D. Walter Heape FRS. A pioneer in reproductive biology. Journal of Reproduction & Fertility 1991; 93: 173–186
- Biggers J. D. Ethical issues and the commercialization of embryo culture media. Reproductive Biomedicine Online 2000; 1: 74–76
- Biggers J. D. Research in the canine block. International Journal of Developmental Biology 2001; 45(3)469–476
- Biggers J. D., Claringbold P. J. Why use inbred lines. Nature 1954; 174: 596–598
- Biggers J. D., McLaren A. ‘Test-tube’ animals. The culture and transfer of early mammalian embryos. Discovery 1958; 19: 423–426
- Biggers J. D., Rinaldini L. M., Webb M. The study of growth factors in tissue culture. Symposia of the Society for Experimental Biology. XI. The biological action of growth substances 1957; 264–297
- Biggers J. D., McLaren A., Michie D. Variance control in the animal house. Nature 1958; 172: 77–80
- Biggers J. D., Whittingham D. G., Donahue D. G. The pattern of energy metabolism in the mouse oocyte and zygote. Proceedings of the National Academy of Sciences USA 1967; 58: 560–567
- Biggers J. D., Bell J. E., Benos D. J. The mammalian blastocyst: Transport functions in a developing epithelium. American Journal of Physiology 1988; 255(Cell Physiology 24)C419–432
- Borland R. M., Biggers J. D., Lechene C. P. Studies on the composition of mouse blastocoele fluid using electron probe microanalysis. Developmental Biology 1977; 55: 1–8
- Cho W. K., Stern S., Biggers J. D. Inhibitory effect of dibutyryl cAMP on mouse oocyte maturation in vitro. Journal of Experimental Zoology 1974; 187: 383–386
- Lawitts J. A., Biggers J. D. Optimization of mouse embryo culture using simplex methods. Journal of Reproduction & Fertility 1991a; 91: 543–556
- Lawitts J. A., Biggers J. D. Overcoming the 2-cell block by lowering the concentration of components in a mouse embryo culture medium. Biology of Reproduction 1991b; 45: 245–251
- Lawitts J. A., Biggers J. D. Culture of preimplantation embryos. Methods in Enzymology 1993; 225: 153–164
- Leese H. J., Biggers J. D., Mroz E. A., Lechene C. Nucleotides in a single mammalian ovum or preimplantation embryo. Analytical Biochemistry 1984; 140: 443–448
- McGinnis L. K., Zhu L., Lawitts J. A., Bhowmick S., Toner M., Biggers J. D. Mouse sperm desiccated and stored in trehalose medium without freezing. Biology of Reproduction 2005; 73: 627–633
- McLaren A., Biggers J. D. Successful development and birth of mice cultivated in vitro as early embryos. Nature 1958; 182: 997–998
Further reading
- Baltz J. M., Lechene C. P., Biggers J. D. Apparent absence of Na+/H+ antiport activity in the two-cell mouse embryo. Developmental Biology 1990; 138: 421–449
- Baltz J. M., Smith S. S., Biggers J. D., Lechene C. Intracellular ion concentrations and their maintenance by Na+/K+-ATPase in preimplantation mouse embryos. Zygote 1997; 5: 1–9
- Biggers J. D. The growth of cartilaginous embryonic chick bones after freezing. Experientia 1957; 13: 483–485
- Biggers J. D. Pioneering mammalian embryo culture. The mammalian preimplantation embryo: Regulation of growth and differentiation in vitro, B D Bavister (Ed.),. Plenum, New York 1987; 1–22
- Biggers J. D. Reflections on the culture of the preimplantation embryo. International Journal of Developmental Biology 1998; 42: 879–884
- Biggers J. D., Creed R. F. S. Placenta haemorphagus organs in the Procyonidae and Mustelidae. Journal of Reproduction & Fertility 1964; 8: 133–137
- Biggers J. D., DeLamater E. D. Marsupial spermatozoa: Paring in the epididymis of American forms. Nature 1965; 208: 402–404
- J. D. Biggers, Schuetz, A. W, 1972. Oogenesis. Baltimore, University Park Press
- Biggers J. D., McGinnis L. K. Evidence that glucose is not always an inhibitor of mouse preimplantation development in vitro. Human Reproduction 2001; 16: 153–163
- Biggers J. D., Racowsky C. The development of fertilized human ova to the blastocyst stage in KSOMAA medium: Is a two-step protocol necessary. Reproductive Biomedicine Online 2002; 5: 133–140
- Biggers J. D., Hare W. C. D., Fritz H. I., McFeely R. A. Chromosomes of American marsupials. Science 1965; 148: 1602–1603
- Biggers J. D., Whitten W. K., Whittingham D. G. The culture of mouse embryos in vitro. Methods of mammalian embryology, J. C. Daniels. Fremman & Co, San Francisco 1971; 86–116
- Biggers J. D., McGinnis L. K., Raffin M. Amino acids and preimplantation development of the mouse in protein-free potassium simplex optimized medium. Biology of Reproduction 2000; 63: 281–293
- Biggers J. D., McGinnis L. K., Lawitts J. A. Enhanced effect of glycyl-L-glutamine on mouse preimplantation embryos in vitro. Reproductive Biomedicine Online 2004; 9: 59–69
- Biggers J. D., McGinnis L. K., Summers M. C. Discrepancies between the effects of glutamine in cultures of mouse preimplantation embryos. Reproductive Biomedicine Online 2004; 9: 70–73
- Biggers J. D., McGinnis L. K., Lawitts J. A. One-step versus two-step culture of mouse preimplantation embryos: Is there a difference. Human Reproduction 2005; 20: 3376–3384
- Borland R. M., Biggers J. D., Lechene C. P. Kinetic aspects of rabbit blastocoele fluid accumulation: An application of electron probe microanalysis. Developmental Biology 1976; 50: 201–211
- Borland R. M., Biggers J. D., Lechene C. P., Taymore M. L. Elemental composition of fluid in the human fallopian tube. Journal of Reproduction & Fertility 1980; 58: 479–482
- Claringbold P. J., Biggers J. D. The response of inbred mice to oestrogens. Journal of Endocrinology 1955; 12: 9–14
- Ducibella T., Albertini D. F., Anderson E., Biggers J. D. The preimplantation mammalian embryo: Characterization of intracellular junctions and their appearance during development. Developmental Biology 1975; 45: 231–250
- L. Mastroianni, Biggers, J. D.. Fertilization and embryonic development in vitro. New York, Plenum. 1981
- Papaioannou V. E., Mkandawire J., Biggers J. D. Development and phenotypic variability of genetically identical half mouse embryos. Development 1989; 106: 817–827
- Powers R. D., Borland R. M., Biggers J. D. Amiloride-sensitive, rheogenic Na+ transport in the rabbit blastocyst. Nature 1977; 270: 602–603
- Stern S., Biggers J. D., Anderson E. Mitochondria and early development of the mouse. Journal of Experimental Zoology 1971; 176: 179–182
- Summers M. C., Biggers J. D. Chemically defined media and the culture of mammalian preimplantation embryos: Historical perspective and current issues. Human Reproduction Update 2003; 9: 557–582
- Summers M. C., Bhatnagar P. R., Lawitts J. A., Biggers J. D. Fertilization in vitro of mouse ova from inbred and outbred strains: Complete preimplantation development in glucose-supplemented KSOM. Biology of Reproduction 1995; 53: 431–437
- Whitten W. K., Biggers J. D. Complete development in vitro of the preimplantation stages of the mouse in a simple chemically defined medium. Journal of Reproduction & Fertility 1968; 17: 399–401