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Cytotherapy Volume 4, 2002 - Issue 5
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Research Article

Immune therapy for EBV infections after hemopoietic stem-cell transplant

H. E. Heslop Center for Cell and Gene Therapy, Baylor College of Medicine, Houston TX, USA
,
C. M. Bollard Center for Cell and Gene Therapy, Baylor College of Medicine, Houston TX, USA
,
S. Gottschalk Center for Cell and Gene Therapy, Baylor College of Medicine, Houston TX, USA
,
I. Kuehnle Center for Cell and Gene Therapy, Baylor College of Medicine, Houston TX, USA
,
M. H. Huls Center for Cell and Gene Therapy, Baylor College of Medicine, Houston TX, USA
,
A. P. Gee Center for Cell and Gene Therapy, Baylor College of Medicine, Houston TX, USA
,
M. K. Brenner Center for Cell and Gene Therapy, Baylor College of Medicine, Houston TX, USA
&
C. M. Rooney Center for Cell and Gene Therapy, Baylor College of Medicine, Houston TX, USA
 show all
Pages 433-434 | Published online: 07 Jul 2009

Reference

  • Gottschalk S, Heslop HE, Rooney CM. Treatment of Epstein—Barr virus-associated malignancies with specific T cells. Adv Cancer Res 2002;84:175–201.
  • Lucas KG, Burton RL, Zimmerman SE et al. Semi-quantitative Epstein—Barr virus (EBV) polymerase chain reaction for the determination of patients at risk for EBV-induced lymphoproliferative disease after stem cell transplantation. Blood 1998;91:3654–61.
  • Papadopoulos EB, Ladanyi M, Emanuel D et al Infusions of donor leukocytes to treat Epstein—Barr virus-associated lymphoproliferative disorders after allogeneic bone marrow transplantation. N Engl .7 Med 1994;330:1185–91.
  • Heslop HE, Brenner MK, Rooney CM. Donor T cells to treat EBV-associated lymphoma. N Engl 7 Med 1994; 331:679–80.
  • Rooney CM, Smith CA, Ng C et al. Use of gene-modified virus-specific T lymphocytes to control Epstein—Barr virus-related lymphoproliferation. Lancet 1995;345:9–13,
  • Heslop HE, Ng CYC, Li C et al. Long-term restoration of immunity against Epstein—Barr virus infection by adoptive transfer of gene-modified virus-specific T lymphocytes. Nat Med 1996;2:551–5.
  • Rooney CM, Smith CA, Ng CYC et al. Infiision of cytotoxic T cells for the prevention and treatment of Epstein—Barr virus-induced lymphoma in allogeneic transplant recipients. Blood 1998;92:1549–55.
  • Gottschalk S, Ng CYC, Smith CA et al. An Epstein—Barr virus deletion mutant that causes fatal lymphoproliferative disease unresponsive to virus-specific T cell therapy. Blood 2001;97:835–43.
  • Bollard C, Onishi H, Huls M et al. Long-term follow-up of patients who received EBV-specific CTLs for the preven-tion or treatment of EBV-associated lymphoproliferative disease [abstract]. Biol Blood Marrow Transplant 2001;7:61.
  • Khanna R, Burrows SR. Role of cytotoxic T lymphocytes in Epstein—Barr virus-associated diseases [in process citation]. Annu Rev Microbiol 2000;54:19–48.
  • Liu Z, Wilson JM, Jones MC et al. Addition of B cell depletion of donor marrow with anti-CD20 antibody to a T cell depletion regimen for prevention of EBV lymphoma after bone marrow transplant [abstract]. Blood 1999;94:638a.
  • Kuehnle I, Huls MH, Liu Z et al. CD20 monoclonal anti-body (rituximab) for therapy of Epstein—Barr virus lymphoma after hemopoietic stem-cell transplantation. Blood 2000;95:1502–5.

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