In vitro expression of erythropoietin by transfected human mesenchymal stromal cells

References

• Dominici M, Hofmann TJ, Horwitz EM. Bone marrow mesenchymal cells: biological properties and clinical applications. J Biol Regul Homeost Agents 2001; 5: 28–37
   Google Scholar
• Mosca JD, Hendricks JK, Buyaner D, et al. Mesenchymal stromal cells as vehicles for gene delivery. Clin Ortho 2000; 379: S71–90
   Google Scholar
• Campagnoli C, Bellantuono I, Kumar S, et al. High transduction efficiency of circulating first trimester fetal mesenchymal stem cells: potential targets for in utero ex vivo gene therapy. Br J Ophthalmol 2002; 109: 952–4
   Google Scholar
• Pereboeva L, Komarova S, Mikheeva G, et al. Approaches to utilize mesenchymal progenitor cells as cellular vehicles. Stem Cells 2003; 21: 389–404
   PubMed Web of Science ®Google Scholar
• Van Damme A, Chuah KL, Dell'accio F, et al. Bone marrow mesenchymal cells for haemophilia A gene therapy using retroviral vectors with modified long-terminal repeats. Haemophilia 2003; 9: 94–103
   PubMed Web of Science ®Google Scholar
• Deng Y, Guo X, Yuan Q, et al. Efficiency of adenoviral vector mediated CTLA4Ig gene delivery into mesenchymal stem cells. Chin Med J 2003; 116: 1649–54
   PubMed Web of Science ®Google Scholar
• PharmData Inc PharmData Signs Contracts with Leader in Stem Cell Research. PharmData Inc., 2002. http://www.pharmdata.com/050202-1.htm (accessed 10 March 2003).
   Google Scholar
• Nakamura K, Ito Y, Kawano Y, et al. Antitumour effect of genetically engineered mesenchymal stromal cells in a rat glioma model. Gene Therapy 2004; 11: 1155–64
   PubMed Web of Science ®Google Scholar
• Hamada H, Kobune M, Nakamura K, et al. Mesenchymal stromal cells (MSC) as therapeutic cytoreagents for gene therapy. Cancer Sci 2005; 96: 149–56
   PubMed Web of Science ®Google Scholar
• Donahue RE, Kessler SW, Bodine D, et al. Helper virus induced T cell lymphoma in nonhuman primates after retroviral mediated gene transfer. J Exp Med 1992; 176: 1125–35
   PubMed Web of Science ®Google Scholar
• Kanzawa T, Ito H, Kondo Y, et al. Current and future gene therapy for malignant gliomas. J Biomed Biotechnol 2003; 1: 25–34
   Google Scholar
• Vorburger SA, Hunt KK. Adenoviral gene therapy. Oncologist 2002; 7: 46–59
   PubMed Web of Science ®Google Scholar
• Schakowski F, Gorschluter M, Junghans C, et al. A novel minimal-size vector (MIDGE) improves transgene expression in colon carcinoma cells and avoids transfections of undesired DNA. Mol Ther 2001; 3: 793–800
   PubMed Web of Science ®Google Scholar
• Krieg AM. Minding the Cs and Gs. Mol Ther 2000; 1: 209–10
   PubMed Web of Science ®Google Scholar
• Yew NS, Zhao H, Wu IH, et al. Reduced inflammatory response to plasmid DNA vectors by elimination and inhibition of immunostimulatory CpG motifs. Mol Ther 2000; 1: 255–62
   PubMed Web of Science ®Google Scholar
• Mok PL, Leong CF, Cheong SK. Isolation and identification of mesenchymal stem cells from human bone marrow. Malaysian J Pathol 2003; 25: 121–7
   PubMedGoogle Scholar
• Choong PF, Mok PL, Cheong SK, et al. Generating neuron-like cells from BM-derived mesenchymal stromal cells in vitro. Cytotherapy 2007; 9: 170–83
   PubMed Web of Science ®Google Scholar
• Fernández M, Simon V, Herrera G, et al. Detection of stromal cells in peripheral blood progenitor cell collections from breast cancer patients. Bone Marrow Transplant 1997; 20: 265–71
   Google Scholar
• Erices A, Conget P, Minguel JJ. Mesenchymal progenitor cells in human umbilical cord blood. Br J Haematol 2000; 109: 235–42
   PubMed Web of Science ®Google Scholar
• Leutenegger CM, Boretti FS, Mislin CN, et al. Immunization of cats against feline immunodeficiency virus (FIV) infection by using minimalistic immunogenic defined gene expression vector vaccines expressing FIV gp140 alone or with feline Interleukin-12 (IL-12), IL-16, or a CpG motif. J Virol 2000; 74: 10447–57
   PubMed Web of Science ®Google Scholar
• López-Fuertes L, Pérez-Jiménez E, Vila-Coro AJ, et al. DNA vaccination with linear minimalistic (MIDGE) vectors confers protection against Leishmania major infection in mice. Vaccine 2002; 21: 247–57
   PubMed Web of Science ®Google Scholar
• Moreno S, López-Fuertes L, Vila-Coro AJ, et al. DNA immunization with minimalistic expression constructs. Vaccine 2004; 22: 1709–16
   PubMed Web of Science ®Google Scholar
• Ohno M, Fornerod M, Mattaj IW. Nucleocytoplasmic transport: the last 200 nanometers. Cell 1998; 92: 327–36
   PubMed Web of Science ®Google Scholar
• Tanswell AK, Staub O, Iles R, et al. Liposome-mediated transfection of fetal lung epithelial cells: DNA degradation and enhanced superoxide toxicity. Am J Physiol Lung Cell Mol Physiol 1998; 275: 452–60
   Web of Science ®Google Scholar
• Liu LN, Hendricks K, Buyaner D, et al. Systemic Erythropoietin Expression from Human Mesenchymal Stem Cells Depends on both Cell Adherence and Delivery Route. International Society for Hematotherapy and Graft Engineering, San Diego, CA 2000
   Google Scholar
• Bartholomew A, Patil S, Mackay A, et al. Baboon mesenchymal stem cells can be genetically modified to secrete human erythropoietin in vivo. Hum Gene Ther 2001; 12: 1527–41
   PubMed Web of Science ®Google Scholar
• Daga A, Muraglia A, Quarto, et al. Enhanced engraftment of EPO-transduced human bone marrow stromal cells transplanted in a 3D matrix in non-conditioned NOD/SCID mice. Gene Ther 2002; 9: 915–21
   PubMed Web of Science ®Google Scholar
• Eliopoulus N, Al-Khaldi A, Crosato M, et al. A neovascularized organoid derived from retrovirally engineered bone marrow stroma leads to prolonged in vivo systemic delivery of erythropoietin in nonmyeloablated, immunocompetent mice. Nature 2003; 10: 478–89
   Google Scholar
• Zanta MA, Belguise-Valladier P, Behr JP. Gene delivery: a single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus. Proc Natl Acad Sci USA 1999; 96: 91–6
   PubMed Web of Science ®Google Scholar
• Zheng C, Juhls C, Oswald D, et al. Effect of different nuclear localization sequences on the immune responses induced by a MIDGE vector encoding bovine herpesvirus-1 glycoprotein D. Vaccine 2006; 24: 4625–9
   PubMed Web of Science ®Google Scholar
• Li M, Lin Y-C, Su KC , et al Magneto-electroporation: enhancement and targeting of gene transfection using magnetic nanoparticles and microchips. The Seventh International Symposium on Micro Total Analysis System (µTAS2003), October 5–9, 2003, California, USA, pp. 1265–9.
   Google Scholar
• Plank C, Scherer F, Schillinger U, et al. Magnetofection: enhancing and targeting gene delivery by magnetic force. Eur Cells Mater 2002; 3(Suppl 2)79–80
   Google Scholar