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Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders Volume 1, 2000 - Issue 2
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Research Article

GDNF is trophic for mouse motoneurons that express a mutant superoxide dismutase (SOD-1) gene

Michael L Derby, Rita Giuliano, Denise A Figlewicz, Martha C Bohn
Pages 113-122 | Published online: 10 Jul 2009

  • Rosen DR, Siddique T, Patterson D, et al. Mutations in Cu/Zn Superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 1993; 362: 59-62.
  • Deng HX, Hentati A, Rainer JA, et al. Amyotrophic lateral sclerosis and structural defects in Cu,Zn Superoxide dismutase. Science 1993; 261: 1047-1051.
  • Gurney ME, Pu H, Chiu AY, et al. Motor neuron degeneration in mice that express a human Cu,Zn Superoxide dismutase mutation. Science 1994; 264: 1772-1775.
  • Ripps ME, Huntley GW, Hof PR, Morrison JH, Gordon JW. Transgenic mice expressing an altered murine Superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis. Proc Natl Acad Sci USA 1995; 92: 689-693.
  • Wong PC, Pardo CA, Borchelt DR, et al. An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron 1995; 14: 1105-1116.
  • McManaman JE, Oppenheim RW. Skeletal muscle-derived neurotrophic factors and motoneuron development. In: Eoughlin WE, Fallaon JH, eds. Neurotrophic factors. San Diego, CA: Academic Press 1993.
  • Oppenheim RW, Yin QW, Prevette D, Yan Q. Brain derived neurotrophic factor rescues developing avian motoneurons from cell death. Nature 1992; 360: 755-757.
  • Sendtner M, Hotmann B, Kolbeck R, Thoenen H, Barde YA. Brain derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section. Nature 1992; 360: 757-759.
  • Yan Q, Elliott J, Snider WD. Brain-derived neurotrophic factor rescues spinal motoneurons from axotomy-induced cell death. Nature 1992; 360: 753-755.
  • Henderson CE, Camu W, Mettling C, et al. Neurotrophins promote motor neuron survival and are present in embryonic limb bud. Nature 1993; 363: 266-270.
  • Koliatsos VE, Cayouette MH, Berkemeier ER, Clatterbuck RE, Price DE, Rosenthal A. Neurotrophin 4/5 is a trophic factor for mammalian facial motor neurons. Proc Natl Acad Sci USA 1994; 91: 3304-3308.
  • Arakawa Y, Sendtner M, Thoenen H. Survival effect of ciliary neurotrophic factor (CNTF) on chick embiyonic motoneurons in culture: comparison with other neurotrophic factors and cytokines. J Neurosci 1990; 10: 3507-3515.
  • Sendtner M, Kretzber GW, Thoenen H. Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy. Nature 1990; 345: 440-441.
  • Oppenheim RW, Prevette D, Yin QW, Collins F, MacDonald J. Control of embryonic motoneuron survival in vitro by ciliary neurotrophic factor. Science 1991; 251: 1616-1618.
  • Martinou JC, Martinou I, Kato AC. Cholinergic differentiation factor (CDF/E1F) promotes survival of isolated rat embiyonic motoneurons in vitro. Neuron 1992; 8: 737-744.
  • Pennica D, Arce V, Swanson TA, et al. Cardiotrophin-1, a cytokine present in embiyonic muscle, supports long-term survival of spinal motoneurons. Neuron 1996; 17: 63-74.
  • Ein EFH, Doherty DH, Eile JD, Bektesh S, Collins F. GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 1993; 260: 1130-1132.
  • Henderson CE, Phillips HS, Pollock RA, et al. GDNF: A potent survival factor for motoneurons present in peripheral nerve and muscle. Science 1994; 266: 1062-1064.
  • Oppenheim RW, Houenou LJ, Johnson JE, et al. Developing motor neurons rescued from programmed and axotomyinduced cell death by GDNF. Nature 1995; 373: 344-346.
  • Van Q, Matheson C, Lopez OT. In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons. Nature 1995; 373: 341-344.
  • Li LX, Wu WT, Lin LFH, Lei M, Oppenheim RW, Houenou LJ. Resale of adult mouse motoneurons from injury-induced cell death by glial cell line-derived neurotrophic factor. Proc Natl Acad Sci USA 1995; 92: 9771-9775.
  • Sagot Y, Tan SA, Baetge E, Schmalbruch II, Kato AC, Aebischer P. Polymer encapsulated cell lines genetically engineered to release ciliary neurotrophic factor can slow down progressive motor neuronopathy in the mouse. Eur J Neurosci 1995; 7: 1313-1322.
  • Choi-Lundberg DL, Bohn MC. Ontogeny and distribution of glial cell line-derived neurotrophic factor (GDNF) mRNA in rat. Brain Res Dev Brain Res 1995; 85: 80-88.
  • Yamamoto M, Sobue G, Yamamoto K, Terao S, Mitsuma T. Expression of glial cell line-derived growth factor mRNA in the spinal cord and muscle in amyotrophic lateral sclerosis. Neurosci Lett 1996; 204: 117-120.
  • Dal Canto MC, Gumey ME. The development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis. Am J Pathol 1994; 145: 1171-1279.
  • Camu W, Henderson CE. Purification of embryonic rat motor neurons by panning on a monoclonal antibody to the low affinity NGF receptor. J Neurosci Methods 1992; 44: 59-70.
  • Ericson J, Thor S, Edlund T, Jessell TM, Yamada T. Early stages of motor neuron differentiation revealed by expression of homeobox gene islet-1. Science 1992; 256: 1555-1560.
  • Sagot Y, Tan SA, Hammang JP, Aebischer P, Kato AC. GDNF slows loss of motoneurons but not axonal degeneration or premature death of pmn/pmn mice. J Neurosci 1996; 16: 2335-2341.
  • Mohajeri MH, Figlewicz DA, Bohn MC. Intramuscular grafts of myoblasts genetically modified to secrete glial cell line-derived neurotrophic factor prevent motoneuron loss and disease progression in a mouse model of familial amyotrophic lateral sclerosis (FALS). Hum Gene Ther 1999; 10: 1853-1866.
  • Nguyen QT, Parsadanian AS, Snider WD, Lichtman JW. Hyperinnervation of neuromuscular junctions caused by GDNF overexpression in muscle. Science 1998; 279: 1725-1729.
  • Pfaff SL, Mendelsohn M, Stewart CL, Edlund T, Jessell TM. Requirements for LIM homeobox gene IsI 1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation. Cell 1996: 84:304-320.
  • Tsuchida T, Ensini M, Mortem SB, Baldassare T, Edlund T, Jessel TM, Pfaff SL. Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes. Cell 1994; 79: 957-970.
  • Thor S, Thomas JB. The drosophila islet gene governs axon pathfinding and neurotransmitter identity. Neuron 1997; 18: 397-409.
  • Thor S, Ericson J, Brannstrom T, Englund T. The homeo-domain LIM IsI-1 is expressed in subsets of neurons and endocrine cells in the adult rat. Neuron 1991; 7: 881-889.
  • Trupp M, Arenas E, Fainzilber M, et al. Functional receptor for GDNF encoded by the c-ret proto-oncogene. Nature 1996; 381: 785-789.
  • Treanor JJS, Goodman L, de Sauvage F, et al. Characterization of a multicomponent receptor for GDNF. Nature 1996; 382: 80-83.
  • Jing S, Wen D, Yu Y, et al. GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-a, a novel receptor for GDNF. Cell 1996; 85: 1113-1124.
  • Durbec P, Marcos-Gutierrez CV, Kilkenny C, et al. GDNF signalling through the ret receptor tyrosine kinase. Nature 1996; 381: 789-793.
  • Seeburger JL, Springer JE. Experimental rationale for the therapeutic use of neurotrophins in amyotrophic lateral sclerosis. Exp Neurol 1993; 124: 64-72.
  • Duberley RM, Johnson IP, Arnand P, Swash M, Martin J, Leigh PN, Zeman S. Ciliary neurotrophic factor expression in spinal cord and motor cortex in amyotrophic lateral sclerosis. J Neurol Sci 1995; 129: 109-116.

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