Advanced search
Publication Cover
Journal of Enzyme Inhibition and Medicinal Chemistry Volume 17, 2002 - Issue 5
Submit an article Journal homepage
541
Views
33
CrossRef citations to date
0
Altmetric
Research Article

Carbonic Anhydrase Inhibitors: Synthesis of Water Soluble Sulfonamides Incorporating a 4-sulfamoylphenylmethylthiourea Scaffold, with Potent Intraocular Pressure Lowering Properties

Angela Casini Università degli Studi di Firenze, Polo Scientifico, Dipartimento di Chimica, Laboratorio di Chimica Bioinorganica, Via della Lastruccia, 3, Rm. 188, I-50019 Sesto Fiorentino (Firenze), Italy
,
Andrea Scozzafava Università degli Studi, Istituto Oculistico, Viale Morgagni 85, I-50134 Firenze, and U.O. Oculistica Az. USL 3, Val di Nievole, Ospedale di Pescia, Pescia, Italy
,
Francesco Mincione Università degli Studi, Istituto Oculistico, Viale Morgagni 85, I-50134 Firenze, and U.O. Oculistica Az. USL 3, Val di Nievole, Ospedale di Pescia, Pescia, Italy
,
Luca Menabuoni Ospedale San Giovanni di Dio, U.O. Oculistica, Via Torregalli 3, I-50123, Firenze, Italy
&
Claudiu T. Supuran Università degli Studi di Firenze, Polo Scientifico, Dipartimento di Chimica, Laboratorio di Chimica Bioinorganica, Via della Lastruccia, 3, Rm. 188, I-50019 Sesto Fiorentino (Firenze), Italy
Pages 333-343 | Published online: 30 Sep 2008

  • Supuran, C.T. and Scozzafava, A. (2002) Exp. Opin. Ther. Patents 12, 217-242.
  • Supuran, C.T. and Scozzafava, A. (2001) Curr. Med. Chem. Imm., Endoc. Metab. Agents 1, 61-97.
  • Supuran, C.T. and Scozzafava, A. (2000) Exp. Opin. Ther. Patents 10, 575-600.
  • Scozzafava, A., Menabuoni, L., Mincione, F., Briganti, F., Mincione, G. and Supuran, C.T. (1999) J. Med. Chem. 42, 2641-2650.
  • Scozzafava, A., Briganti, F., Mincione, G., Menabuoni, L., Mincione, F. and Supuran, C.T. (1999) J. Med. Chem. 42, 3690-3700.
  • Scozzafava, A., Banciu, M.D., Popescu, A. and Supuran, C.T. (2000) J. Enz. Inhib. 15, 533-546.
  • Ilies, M., Supuran, C.T., Scozzafava, A., Casini, A., Mincione, F., Menabuoni, L., Caproiu, M.T., Maganu, M. and Banciu, M.D. (2000) Bioorg. Med. Chem. 8, 2145-2155.
  • Casini, A., Scozzafava, A., Mincione, F., Menabuoni, L., Ilies, M.A. and Supuran, C.T. (2000) J. Med. Chem. 43, 4884-4892.
  • McKee, R.L. and Bost, R.W. (1946) J. Am. Chem. Soc. 68, 2506-2507.
  • Lindskog, S., Behravan, G., Engstrand, C., Foreman, C., Jonsson, B.H., Liang, Z., Ren, X. and Xue, Y. (1991) "Structure-function relations in human carbonic anhydrase II as studied by site-directed mutagenesis", In: Botrè, F., Gros, G. and Storey, B.T., eds, Carbonic Anhydrase--From Biochemistry and Genetics to Physiology and Clinical Medicine (VCH, Weinheim), pp 1-13.
  • Behravan, G., Jonsson, B.H. and Lindskog, S. (1990) Eur. J. Biochem. 190, 351-357.
  • Khalifah, R.G., Strader, D.J., Bryant, S.H. and Gibson, S.M. (1977) Biochemistry 16, 2241-2247.
  • Lindskog, S. and Coleman, J.E. (1964) Proc. Natl Acad. Sci. USA 70, 2505-2508.
  • Steiner, H., Jonsson, B.H. and Lindskog, S. (1975) Eur. J. Biochem. 59, 253-259.
  • Maren, T.H., Wynns, G.C. and Wistrand, P.J. (1993) Mol. Pharmacol. 44, 901-906.
  • Pocker, Y. and Stone, J.T. (1967) Biochemistry 6, 668-678.
  • Baird, T.T., Waheed, A., Okuyama, T., Sly, W.S. and Fierke, C.A. (1997) Biochemistry 36, 2669-2678.
  • Supuran, C.T., Ilies, M.A. and Scozzafava, A. (1998) Eur. J. Med. Chem. 33, 739-751.
  • Maren, T.H., Brechue, W.F. and Bar-Ilan, A. (1992) Exp. Eye Res. 55, 73-79.
  • Brechue, W.F. and Maren, T.H. (1993) Investing. Ophthalmol. Vis. Sci. 34, 2581-2587.
  • Sugrue, M.F., Gautheron, P., Mallorga, P., Nolan, T.E., Graham, S.L., Schwam, H., Shepard, K.L. and Smith, R.L. (1990) Br. J. Pharmacol. 99, 59-64.
  • Pierce, Jr, W.M., Sharir, M., Waite, K.J., Chen, D. and Kaysinger, K.K. (1993) Proc. Soc. Exp. Biol. Med. 203, 360-365.
  • Sharir, M., Pierce, Jr, W.M., Chen, D. and Zimmerman, T.J. (1994) Exp. Eye Res. 58, 107-116.
  • Browne, D.W. and Dyson, G.M. (1931) J. Chem. Soc. 3285-33909.
  • Browne, D.W. and Dyson, G.M. (1934) J. Chem. Soc. 178-179.
  • Briganti, F., Mangani, S., Orioli, P., Scozzafava, A., Vernaglione, G. and Supuran, C.T. (1997) Biochemistry 36, 10384-10392.
  • Supuran, C.T. and Clare, B.W. (1995) Eur. J. Med. Chem. 30, 687-696.
  • Clare, B.W. and Supuran, C.T. (1999) Eur. J. Med. Chem. 34, 463-474.
  • Scozzafava, A., Banciu, M.D., Popescu, A. and Supuran, C.T. (2000) J. Enz. Inhib. 15, 443-453.
  • Menabuoni, L., Scozzafava, A., Mincione, F., Briganti, F., Mincione, G. and Supuran, C.T. (1999) J. Enz. Inhib. 14, 457-474.
  • Maren, T.H. (1995) J. Glaucoma. 4, 49-62.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.