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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 19, 2004 - Issue 1

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Synthesis of Hydroxy Derivatives of Highly Potent Non-steroidal CYP 17 Inhibitors as Potential Metabolites and Evaluation of their Activity by a Non Cellular Assay using Recombinant Human Enzyme

Tilman U. Hutschenreuter 8.5 Pharmaceutical and Medicinal Chemistry, Saarland University, P.O. Box, D-66041, Saarbrücken, Germany

Peter B. Ehmer 8.5 Pharmaceutical and Medicinal Chemistry, Saarland University, P.O. Box, D-66041, Saarbrücken, Germany

Rolf W. Hartmann 8.5 Pharmaceutical and Medicinal Chemistry, Saarland University, P.O. Box, D-66041, Saarbrücken, GermanyCorrespondence[email protected]

Pages 17-32 | Received 25 Jul 2003, Accepted 25 Sep 2003, Published online: 03 Oct 2008

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https://doi.org/10.1080/14756360310001640913

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Synthesis of Hydroxy Derivatives of Highly Potent Non-steroidal CYP 17 Inhibitors as Potential Metabolites and Evaluation of their Activity by a Non Cellular Assay using Recombinant Human Enzyme

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Synthesis of Hydroxy Derivatives of Highly Potent Non-steroidal CYP 17 Inhibitors as Potential Metabolites and Evaluation of their Activity by a Non Cellular Assay using Recombinant Human Enzyme

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