References
- MM Cherrier, S Asthana, S Plymate, L Baker, AM Matsumoto, E Peskind, MA Raskind, K Brodkin, W Bremner, A Petrova, S LaTendresse, and S Craft. (2001). Testosterone supplementation improves spatial and verbal memory in healthy older men. Neurology 57:80–88.
- JS Janowsky, SK Oviatt, and ES Orwoll. (1994). Testosterone influences spatial cognition in older men. Behav Neurosci 108:325–332.
- JS Janowsky, B Chavez, and E Orwoll. (2000). Sex steroids modify working memory. J Cognitive Neurosci 12:407–414.
- JE Morley, F Kaiser, WJ Raum, HM Perry, JF Flood, J Jensen, AJ Silver, and E Roberts. (1997). Potentially predictive and manipulable blood serum correlates of aging in the healthy human male: Progressive decreases in bioavailable testosterone, dehydroepiandrosterone sulfate, and the ratio of insulin-like growth factor 1 to growth hormone. Proc Natl Acad Sci USA 94:7537–7542.
- E Barrett-Connor, D Goodman-Gruen, and B Patay. (1999). Endogenous sex hormones and cognitive function in older men. J Clin Endocrinol Metab 84:3681–3685.
- E Hogervorst, J Lehmann, J McBroom, and D Smith. (2002). Apolipoprotein Eε4 and testosterone interact in the risk of Alzheimer's disease in men. Int J Geriatr Psychiatry 10:938–940.
- S Moffat. (2005). Effects of testosterone on cognitive and brain aging in elderly men. Ann NY Acad Sci 1055:80–92.
- M Cherrier, A Matsumoto, J Amory, S Asthana, W Bremner, E Peskind, M Raskind, and S Craft. (2005). Testosterone improves spatial memory in men with Alzheimer disease and mild cognitive impairment. Neurology 64:2063–2068.
- DA Gruenewald, and AM Matsumoto. (2003). Testosterone supplementation therapy for older men: Potential benefits and risks. J Am Geriat Soc 51:101–115.
- E Hogervorst, S Bandelow, and SD Moffat. (2005). Increasing testosterone levels and effects on cognitive functions in elderly men and women: A review. Curr Drug Targets CNS Neurol Disorder 4:531–540.
- GK Gouras, H Xu, RS Gross, JP Greenfield, B Hai, R Wang, and P Greengard. (2000). Testosterone reduces neuronal secretion of Alzheimer's β-amyloid peptides. Proc Natl Acad Sci USA 97:1202–1205.
- RS Tan, and SJ Pu. (2003). A pilot study on the effects of testosterone in hypogonadal aging male patients with Alzheimer's disease. The Aging Male 6:13–17.
- EK Perry. (1986). The cholinergic hypothesis ten years on. Br Med Bull 42:63–69.
- NH Greig, T Utsuki, DK Ingram, Y Wang, G Pepeu, C Scali, QS Yu, J Mamczarz, HW Holloway, T Giordano, D Chen, K Furukawa, K Sambamurti, A Brossi, and DK Lahiri. (2005). Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer beta-amyloid peptide in rodent. Proc Natl Acad Sci USA 102:17213–17218.
- E Giacobini. (2001). Selective inhibitors of butyrylcholinesterase: A valid alternative for therapy of Alzheimer's disease?. Drugs Aging 18:891–898.
- GL Ellman, KD Courtney, V Andres, and RM Featherstone. (1961). A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 7:88–95.
- A Al-Aboudi, M Yasin, G Musharraf, MI Choudhary, and A Ur-Rahman. (2008). Nat Prod Res (accepted for publication)
- P Fernandes, A Cruz, B Angelova, HM Pinheiro, and JS Cabral. (2003). Microbial conversion of steroid compounds: Recent developments. Enz Microb Technol 32:688–705.
- A Saxena, AM Redman, X Jiang, O Lockridge, and BP Doctor. (1997). Differences in active site gorge dimensions of cholinesterases revealed by binding of inhibitors to human butyrylcholinesterase. Biochemistry 36:14642–14651.
- IH Segel. Enzyme Kinetics Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems. New York: Wiley; (1975) p 101–112.