References
- M Martínez. The medicial plants of Mexico 1967. p 125–127, ed. Ed. Botas. México.
- JJ Mandoki, C Krumm-Heller, J Vega-Noverola, C Wong-Ramírez, C Arriaga, R Roa, C Rubio, N Mendoza-Patiño. Isolation of α-asarone from the bark of Guatteria gaumeri (Elemuy) and the study of its hypocholesterolemic effect 1980., IV National Congress of Pharmacology, University of Yucatán, Mérida, Yucatán, México.
- J Poplawski, B Lozowicka, AT Dubis, B Lachowska, S Witkowski, D Siluk, J Petrusewic, R Kaliszan, J Cybulski, M Strzalkowska, Z Chilmoneczyk. Synthesis and hypolipidemic and antiplatelet activities of alpha-asarone isomers in humans (in vitro), mice (in vivo), and rats (in vivo). J Med Chem 2000;43:3671–3676.
- L Rodriguez-Paez, M Juarez-Sanchez, J Antunez-Solis, I Baeza, C Wong. Alpha-asarone inhibits HMG-CoA reductase, lowers serum LDL-cholesterol levels and reduces biliary CSI in hypercholesterolemic rats. Phytomedicine 2003;10:397–404.
- AJ Howes, VS Chan, J Caldwell. Structure-specificity of the genotoxicity of some naturally occurring alkenil benzenes determined by the unscheduled DNA synthesis assay in rat hepatocytes. Food Chem Toxicol 1990;28:537–542.
- E Hasheminejad, J Caldwell. Genotoxicity of the alkenylbenzenes alpha- and beta-asarone, myristicin and elimicin as determined by the UDS assay in cultured rat hepatocytes. Food Chem Toxicol 1994;32:223–231.
- RW Wiseman, EC Miller, JA Miller, A Liem. Structure–activity studies of the hepatocarcinogenicities of alkenylbenzene derivatives related to estragole and safrole on administration to preweanling male C57BL/6J × C3H/HeJ F1 mice. Cancer Res 1987;47:2275–2283.
- GR Wilkinson. Pharmacokinetics: The dynamics of drug absorption, distribution, and elimination. In: JG Hardman, LE Limbird. Goodman & Gilman's the pharmacological basis of therapeutics. New York: Mc Graw-Hill; 2001. p. 12–16.
- NIH. Guide for the care and use of laboratory animals Office of Sciences and Health Report DRR/NIH DHEW Publication 1985. p 85–123.
- SD Turley, JM Dietschy. Re-evaluation of the 3-α-hidroxysteroid dehydrogenase assay for total bile acids in bile. J Lipid Res 1978;19:924–928.
- MC Carey. Critical tables for calculating the cholesterol saturation of native bile. J Lipid Res 1978;19:998–1026.
- A Kleinsek, S Ranganathan, JW Porter. Purification of 3-hydroxy-3-methylglutaryl-coenzyme A reductase from rat liver. Proc Natl Acad Sci U S A 1977;74:1431–1435.
- ZH Beg, JA Stonik, HB Brewer. Purification and characterization of 3-hydroxy-3-methylglutaryl coenzyme A reductase from chicken liver. FEBS Lett 1977;80:123–129.
- SJ Kim, SH Bok, MK Lee, YB Park, HJ Kim, MS Choi. Lipid-lowering efficacy of 3,4-di(OH)-phenylpropionic l-leucine in high-cholesterol fed rats. J Biochem Mol Toxicol 2005;19:25–31.
- CA Gleissner, N Leitinger, K Ley. Effects of native and modified low-density lipoproteins on monocyte recruitment in atherosclerosis. Hypertension 2007;50:276–283.
- JC Fruchart, P Duriez. Anti-cholesterol agents, new therapeutic approaches. Ann Pharm Fr 2004;62:3–18.
- ES Istvan, J Deisenhofer. Structural mechanism for statin Inhibition of HMG-CoA reductase. Science 2001;29:1160–1164.
- SD Turley. Cholesterol metabolism and therapeutic targets, rationale for targeting multiple metabolic pathways. Clin Cardiol 2004;27:III16–III21.
- MS Brown, JL Goldstein. A receptor-mediated pathway for cholesterol homeostasis. Science 1986;232:34–47.
- AJ Lusis. Atherosclerosis. Nature 2000;407:233–241.
- T Clerc, M Jomier, M Chautan, H Portugal, M Senft, A Pauli, C Laruelle, O Morel, H Lafont, F Chanussot. Mechanism of action in the liver of crilvastatin, a new hydroxy-methylglutaryl-coenzyme A reductase inhibitor. Eur J Pharm 1993;235:59–68.
- AS Wierzbicki. Lipid-altering therapies and the progression of atherosclerotic disease. Cardiovasc Intervent Radiol 2007;30:155–160.
- PD Roach, S Balasubramaniam, F Hirata, M Abbey, A Szanto, LA Simons, PJ Nestel. The low-density lipoprotein receptor and cholesterol synthesis are affected differently by dietary cholesterol in the rat. Biochim Biophys Acta 1993;1170:165–172.
- ZR Vlahcevic, DM Heuman, PB Hylemon. Regulation of bile acid synthesis. Hepatology 1991;13:590–600.
- MS Straka, LH Junker, L Zacarro, DR Zogg, S Dueland, GT Everson, RAJ Davis. Substrate stimulation of 7-alpha-hydroxylase, an enzyme located in the cholesterol-poor endoplasmic reticulum. J Biol Chem 1990;265:7145–7149.
- MP Jones, WM Pandak, DM Heuman, JY Chang, PB Hylemon, ZR Vlahcevic. Cholesterol 7-alpha-hydroxylase, evidence for transcriptional regulation by cholesterol or metabolic products of cholesterol in the rat. J Lipid Res 1992;34:385–392.
- CM Carey, DM Small. The characteristics of mixed micellar solution with particular reference to bile. Am J Med 1970;49:590–608.
- DM Small. The formation of gallstones. Adv Intern Med 1970;16:243–264.
- OJ Smith, DW Erkelens, GP Von Berger Henegorwen. Successful dissolution of cholesterol gallstones during treatment with pravastatin. Gastroenterology 1992;103:1068–1070.
- RG Danzinger, AF Hofmann, LJ Schoenfield, JI Thistle. Dissolution of cholesterol gallstones by chenodeoxycholic acid. N Engl J Med 1972;286:1–8.
- C Gómez, G Chamorro, MA Chávez, G Martínez, M Salazar, N Pages. Effect of α-asarone on hypercholesterolemia and on experimental. cholelitiasis. Plant Med Phytother 1987;21:279–284.