Biological activity of bis-benzimidazole derivatives on DNA topoisomerase I and HeLa, MCF7 and A431 cells

References

• CJ Matthews, V Broughton, G Bernardinelli, X Melich, G Brand, AC Wills, AF Williams. Molecular bricklaying: The protonated benzimidazole moiety as a synthon for crystal engineering. New J Chem 2003;27:354–358.
   Web of Science ®Google Scholar
• WR Roderick, CW NordeenJr., AM Von Esch, RN Appell. Bisbenzimidazoles. Potent inhibitors of rhinoviruses. J Med Chem 1972;15:655–658.
   PubMed Web of Science ®Google Scholar
• NM Agh-Atabay, B Dulger, F Gucin. Synthesis and investigation of antimicrobial activity of some bisbenzimidazole-derived chelating agents. Eur J Med Chem 2003;38:875–881.
   PubMed Web of Science ®Google Scholar
• F Arjmand, B Mohani, S Ahmad. Synthesis, antibacterial, antifungal activity and interaction of CT-DNA with a new benzimidazole derived Cu(II) complex. Eur J Med Chem 2005;40:1103–1110.
   PubMed Web of Science ®Google Scholar
• HS Gunes, G Cosar. Synthesis of some hydroxamic acid derivatives of benzimidazole and their antibacterial and antifungal activities. Arzneim-Forsch/Drug Res 1992;42:1045–1048.
   PubMed Web of Science ®Google Scholar
• JS Kim, Q Sun, C Yu, A Liu, LF Liu, EJ LaVoie. Quantative structure-activity relationships on 5-substituted terbenzimidazoles as topoisomerase I poisons and antitumor agents. Bioorg Med Chem 1998;6:163–172.
   PubMed Web of Science ®Google Scholar
• H Malaty, HMT El-Zimaity, RM Gentra, RA Cole, DY Graham. High-dose proton pump inhibitor plus amoxycillin for the treatment or retreatment of Helicobacter pylori infection. Aliment Pharm Therap 1996;10 (6):1001–1004.
   PubMed Web of Science ®Google Scholar
• Q Sun, B Gatto, C Yu, A Liu, LF Leroy, EJ La Voie. Structure activity of topisomerase I poisons related to Hoechst 33342. Bioorg Med Chem 1994;4 (24):2871–2876.
   Web of Science ®Google Scholar
• S Jin, JS Kim, S Sim, A Liu, DS Pilch, LF Liu, EJ La Voie. Heterocyclic bibenzimidazole derivatives as topoisomerase I ınhibitors. Bioorg Med Chem Lett 2000;10:719–723.
   PubMed Web of Science ®Google Scholar
• A Seaton, C Higgins, J Mann, A Baron, C Bailly, S Neidle, H Van den Berg. Mechanistic and anti-proliferative studies of two novel, biologically active bis-benzimidazoles. Eur J Cancer 2003;39:2548–2555.
   PubMed Web of Science ®Google Scholar
• AS Alpan, HS Gunes, Z Topcu. 1H-Benzimidazole derivatives as mammalian DNA topoisomerase I inhibitors. Acta Biochim Pol 2007;54 (3):561–565.
   PubMed Web of Science ®Google Scholar
• JC Wang. DNA topoisomeases. Ann Rev Biochem 1996;65:635–692.
   PubMed Web of Science ®Google Scholar
• MA Bjornsti, N Osheroff. DNA topology and enzymes. Totowa, New Jersey: Humana Press; 1999.
   Google Scholar
• JS Kim, C Yu, A Liu, LF Liu, EJ La Voie. Terbenzimidazoles: Influence of 2″-, 4- and 5-substituents on cytotoxicity and relative potency as topoisomerase I poisons. J Med Chem 1997;40:2818–2824.
   PubMed Web of Science ®Google Scholar
• Z Topcu. DNA topoisomerases as targets for anticancer drugs. J Clin Pharm Ther 2001;26:405–416.
   PubMed Web of Science ®Google Scholar
• C Martín-Cordero, M López-Lázaro, M Gálvez, MJ Ayuso. Curcumin as a DNA topoisomerase II poison. J Enz Inhib Med Chem 2003;18:505–509.
   PubMed Web of Science ®Google Scholar
• CJ Thomas, NJ Rahier, SM Hecht. Camptothecin: Current perspectives. Bioorg Med Chem 2004;12 (7):1585–1604.
   PubMed Web of Science ®Google Scholar
• M Gálvez, C Martín-Cordero, MJ Ayuso. Iridoids as DNA topoisomerase I poisons. J Enz Inhib Med Chem 2005;20:389–392.
   PubMed Web of Science ®Google Scholar
• A Esteves-Souza, K Pissinate, MG Nascimento, NF Grynberg. Synthesis, cytotoxicity and DNA-topoisomerase inhibitory activity of new asymmetric ureas and thioureas. Bioorg Med Chem 2006;14 (2):492–499.
   PubMed Web of Science ®Google Scholar
• MPS Ishar, G Singh, S Singh, KK Sreenivasan, G Singh. Design, synthesis, and evluation of novel 6-chloro-/fluorochromone derivatives as potential topoisomerase inhibitor anticancer agents. Bioorg Med Chem Lett 2006;16:1366–1370.
   PubMed Web of Science ®Google Scholar
• T Mosmann. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 1983;65:55–63.
   PubMed Web of Science ®Google Scholar
• Z Topcu, FJ Castora. Mammalian mitochondrial DNA topoisomerase I preferentially relaxes supercoils in plasmids containing specific mitochondrial DNA sequences. Biochim Biophys Acta 1995;1264:377–387.
   PubMed Web of Science ®Google Scholar
• Z Topcu. Densitometric quantification of DNA topoisomers in ethidium bromide-stained agarose gels and chemiluminescence-detected X ray films. Acta Biochim Pol 2000;47:835–839.
   PubMed Web of Science ®Google Scholar
• M Hesse, H Meier, B Zeeh. In: D Enders, R Noyori, BM Trost, editors. Spectroscopic methods in organic chemistry. New York: Georg Thieme Verlag Stuttgart; 1997.
   Google Scholar