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Research Article

Encapsulation of anti-carbonic anhydrase IX antibody in hydrogel microspheres for tumor targeting

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Pages 110-118 | Received 18 Feb 2016, Accepted 06 Apr 2016, Published online: 03 May 2016

References

  • Tomaro-Duchesneau C, Saha S, Malhotra M, et al. Microencapsulation for the therapeutic delivery of drugs, live mammalian and bacterial cells, and other biopharmaceutics: current status and future directions. J Pharmacol 2013;2013:103527
  • Scharp DW, Marchetti P. Encapsulated islets for diabetes therapy: history, current progress, and critical issues requiring solution. Adv Drug Deliv Rev 2014;67-68:35–73.
  • Weir GC. Islet encapsulation: advances and obstacles. Diabetologia 2013;56:1458–61.
  • Sun J, Tan H. Alginate-based biomaterials for regenerative medicine applications. Materials 2014;6:1285–309.
  • Lacik I. Current status on immunoprotection of transplanted islets: focus on islet microencapsulation. Micro Nanosyst 2013;5:168–76.
  • Wang T, Lacik I, Brissova M, et al. An encapsulation system for the immunoisolation of pancreatic islets. Nat Biotechnol 1997;15:358–62.
  • Qi M, Lacik I, Kollarikova G, et al. A recommended laparoscopic procedure for implantation of microcapsules in the peritoneal cavity of non-human primates. J Surg Res 2011;168:e117–23.
  • Lacik I, Brissova M, Anilkumar AV, et al. New capsule with tailored properties for the encapsulation of living cells. J Biomed Mater Res 1998;39:52–60.
  • Nelson AL, Dhimolea E, Reichert JM. Development trends for human monoclonal antibody therapeutics. Nat Rev Drug Discov 2010;9:767–74.
  • Marquette S, Peerboom C, Yates A, et al. Encapsulation of immunoglobulin G by solid-in-oil-in-water: effect of process parameters on microsphere properties. Eur J Pharm Biopharm 2014;86:393–403.
  • Jain RK, Stylianopoulos T. Delivering nanomedicine to solid tumors. Nat Rev Clin Oncol 2010;7:653–64.
  • Wagner E. Programmed drug delivery: nanosystems for tumor targeting. Exp Opin Biol Ther 2007;7:587–93.
  • Pastorekova S, Zavadova Z, Kostal M, et al. A novel quasi-viral agent, MaTu, is a two-component system. Virology 1992;187:620–6.
  • Pastorek J, Pastorekova S, Callebaut I, et al. Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment. Oncogene 1994;9:2877–88.
  • Wykoff CC, Beasley NJ, Watson PH, et al. Hypoxia-inducible expression of tumor-associated carbonic anhydrases. Cancer Res 2000;60:7075–83.
  • Supuran CT. Carbonic anhydrases: novel therapeutic applications for inhibitors and activators. Nat Rev Drug Discov 2008;7:168–81.
  • Zatovicova M, Jelenska L, Hulikova A, et al. Carbonic anhydrase IX as an anticancer therapy target: preclinical evaluation of internalizing monoclonal antibody directed to catalytic domain. Curr Pharm Des 2010;16:3255–63.
  • Zavada J, Zavadova Z, Pastorek J, et al. Human tumour-associated cell adhesion protein MN/CA IX: identification of M75 epitope and of the region mediating cell adhesion. Br J Cancer 2000;82:1808–13.
  • Chrastina A, Zavada J, Parkkila S, et al. Biodistribution and pharmacokinetics of 125I-labeled monoclonal antibody M75 specific for carbonic anhydrase IX, an intrinsic marker of hypoxia, in nude mice xenografted with human colorectal carcinoma. Int J Cancer 2003;105:873–81.
  • De Vos P, De Haan BJ, Wolters GH, et al. Improved biocompatibility but limited graft survival after purification of alginate for microencapsulation of pancreatic islets. Diabetologia 1997;40:262–70.
  • Kishino K, Kawai T, Nose T, et al. Dilute solution properties of sodium cellulose disulphate. Eur Polym J 1981;17:623–30.
  • Qi M, Strand BL, Morch Y, et al. Encapsulation of human islets in novel inhomogeneous alginate-Ca2+/Ba2+ microbeads: in vitro and in vivo function. Artif Cells Blood Subst Immobil Biotechnol 2008;36:403–20.
  • Qi M, Morch Y, Lacik I, et al. Survival of human islets in microbeads containing high guluronic acid alginate crosslinked with Ca2+ and Ba2+. Xenotransplantation 2012;19:355–64.
  • Bucko M, Vikartovska A, Lacik I, et al. Immobilization of a whole-cell epoxide-hydrolyzing biocatalyst in sodium alginate–cellulose sulfate–poly(methylene-co-guanidine) capsules using a controlled encapsulation process. Enzyme Microb Technol 2005;36:118–26.
  • Bucko M, Schenkmayerova A, Gemeiner P, et al. Continuous testing system for Baeyer-Villiger biooxidation using recombinant Escherichia coli expressing cyclohexanone monooxygenase encapsulated in polyelectrolyte complex capsules. Enzyme Microb Technol 2011;49:284–8.
  • Vikartovska A, Bucko M, Mislovicova D, et al. Improvement of the stability of glucose oxidase via encapsulation in sodium alginate–cellulose sulfate–poly(methylene-co-guanidine) capsules. Enzyme Microb Technol 2007;41:748–55.
  • Qi M, McGarrigle JJ, Wang Y, et al. Transplantation of pancreatic islets immobilized in alginate-based microcapsules: from animal studies to clinical trials. Micro Nanosyst 2013;5:186–93.
  • Anilkumar AV, Lacik I, Wang TG. A novel reactor for making uniform capsules. Biotechnol Bioeng 2001;75:581–9.
  • Pelegrin M, Marin M, Noel D, et al. Systemic long-term delivery of antibodies in immunocompetent animals using cellulose sulphate capsules containing antibody-producing cells. Gene Ther 1998;5:828–34.
  • Pelegrin M, Marin M, Oates A, et al. Immunotherapy of a viral disease by in vivo production of therapeutic monoclonal antibodies. Human Gene Ther 2000;11:1407–15.
  • Dubrot J, Portero A, Orive G, et al. Delivery of immunostimulatory monoclonal antibodies by encapsulated hybridoma cells. Cancer Immunol Immunother 2010;59:1621–31.
  • Lee AL, Ng VW, Gao S, et al. Injectable biodegradable hydrogels from vitamin D-functionalized polycarbonates for the delivery of avastin with enhanced therapeutic efficiency against metastatic colorectal cancer. Biomacromolecules 2015;16:465–75.
  • Morch YA, Donati I, Strand BL, Skjak-Braek G. Effect of Ca2+, Ba2+, and Sr2+ on alginate microbeads. Biomacromolecules 2006;7:1471–80.
  • Rokstad AM, Brekke OL, Steinkjer B, et al. Alginate microbeads are complement compatible, in contrast to polycation containing microcapsules, as revealed in a human whole blood model. Acta Biomater 2011;7:2566–78.
  • Vaithilingam V, Kollarikova G, Qi M, et al. Effect of prolonged gelling time on the intrinsic properties of barium alginate microcapsules and its biocompatibility. J Microencapsul 2011;28:499–507.
  • Brissova M, Petro M, Lacik I, et al. Evaluation of microcapsule permeability via inverse size exclusion chromatography. Anal Biochem 1996;242:104–11.
  • de Vos P, Bucko M, Gemeiner P, et al. Multiscale requirements for bioencapsulation in medicine and biotechnology. Biomaterials 2009;30:2559–70.
  • Gu F, Amsden B, Neufeld R. Sustained delivery of vascular endothelial growth factor with alginate beads. J Control Release 2004;96:463–72.
  • Ferrara N, Houck KA, Jakeman LB, et al. The vascular endothelial growth factor family of polypeptides. J Cell Biochem 1991;47:211–18.
  • Goolcharran C, Cleland JL, Keck R, et al. Comparison of the rates of deamidation, diketopiperazine formation and oxidation in recombinant human vascular endothelial growth factor and model peptides. AAPS PharmSci 2000;2:E5.
  • Helmlinger G, Yuan F, Dellian M, Jain RK. Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation. Nat Med 1997;3:177–82.
  • Harris AL. Hypoxia – a key regulatory factor in tumour growth. Nat Rev Cancer 2002;2:38–47.
  • Sedlakova O, Svastova E, Takacova M, et al. Carbonic anhydrase IX, a hypoxia-induced catalytic component of the pH regulating machinery in tumors. Front Physiol 2014;4:400. doi:10.3389/fphys.2013.00400.
  • Available from: http://www.brenda-enzymes.org/enzyme.php?ecno=1.1.3.4 [last accessed 20 May 2015].
  • Rokstad AM, Lacik I, de Vos P, Strand BL. Advances in biocompatibility and physico-chemical characterization of microspheres for cell encapsulation. Adv Drug Deliv Rev 2014;67–68:111–30.

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