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Research Article

Inhibition of Bacillus anthracis metallo-β-lactamase by compounds with hydroxamic acid functionality

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Pages 132-137 | Received 24 Mar 2016, Accepted 20 Jul 2016, Published online: 25 Aug 2016

References

  • Collier RJ, Young JA. Anthrax toxin. Annu Rev Cell Dev Biol 2003;19:45–70
  • Beharry Z, Chen H, Gadhachanda VR, et al. Evaluation of penicillin-based inhibitors of the class A and B beta-lactamases from Bacillus anthracis. Biochem Biophys Res Commun 2004;313:541–5
  • Bebrone C. Metallo-beta-lactamases (classification, activity, genetic organization, structure, zinc coordination) and their superfamily. Biochem Pharmacol 2007;74:1686–701
  • Materon IC, Queenan AM, Koehler TM, et al. Biochemical characterization of beta-lactamases Bla1 and Bla2 from Bacillus anthracis. Antimicrob Agents Chemother 2003;47:2040–2
  • Schlesinger SR, Kim SG, Lee JS, et al. Purification development and characterization of the zinc-dependent metallo-β-lactamase from Bacillus anthracis. Biotechnol Lett 2011;33:1417–22
  • Buynak JD, Chen H, Vogeti L, et al. Penicillin-derived inhibitors that simultaneously target both metallo- and serine-beta-lactamases. Bioorg Med Chem Lett 2004;14:1299–304
  • Kim SK, Sims CL, Wozniak SE, et al. Antibiotic resistance in bacteria: novel metalloenzyme inhibitors. Chem Biol Drug Des 2009;74:343–8
  • Spencer J, Walsh TR. A new approach to the inhibition of metallo-beta-lactamases. Angew Chem Int Ed Engl 2006;45:1022–6
  • Schlesinger SR, Bruner B, Farmer PJ, et al. Kinetic characterization of a slow-binding inhibitor of Bla2: thiomaltol. J Enzyme Inhib Med Chem 2013;28:137–42
  • Puerta DT, Cohen SM. Elucidating drug-metalloprotein interactions with tris(pyrazolyl)borate model complexes. Inorg Chem 2002;41:5075–82
  • Walter MW, Valladares M, Adlington RM, et al. Hydroxamate inhibitors of aeromonas hydrophila AE036 Metallo-beta-lactamase. Bioorg Chem 1999;27:35–40
  • Lienard BM, Horsfall LE, Galleni M, et al. Inhibitors of the FEZ-1 metallo-beta-lactamase. Bioorg Med Chem Lett 2007;17:964–8
  • Gottlieb HE, Kotlyar V, Nudelman A. NMR chemical shifts of common laboratory solvents as trace impurities. J Org Chem 1997;62:7512–15
  • Shin H, Gennadios HA, Whittington DA, et al. Amphipathic benzoic acid derivatives: synthesis and binding in the hydrophobic tunnel of the zinc deacetylase LpxC. Bioorg Med Chem 2007;15:2617–23
  • Nguyen HD, Phan TT, Schumann W. Expression vectors for the rapid purification of recombinant proteins in Bacillus subtilis. Curr Microbiol 2007;55:89–93
  • Cutting SM, Horn PBV. Gene cloning techniques. In: Harwood CR, Cutting SM, eds. Molecular biological methods for Bacillus. New York: John Wiley and Sons, Inc.;1990:27–74
  • Sali A, Blundell TL. Comparative protein modelling by satisfaction of spatial restraints. J Mol Biol 1993;234:779–815
  • Laskowsk RA, MacArthur MW, Moss D, et al. PROCHECK: a program to check the stereochemical quality of protein structures. J Appl Cryst 1993;26:283–91
  • Benkert P, Tosatto SC, Schomburg D. QMEAN: a comprehensive scoring function for model quality assessment. Proteins 2008;71:261–77
  • Trott O, Olson AJ. AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. J Comput Chem 2010;31:455–61
  • Payne DJ, Bateson JH, Gasson BC, et al. Inhibition of metallo-beta-lactamases by a series of mercaptoacetic acid thiol ester derivatives. Antimicrob Agents Chemother 1997;41:135–40
  • Toney JH, Hammond GG, Fitzgerald PM, et al. Succinic acids as potent inhibitors of plasmid-borne IMP-1 metallo-beta-lactamase. J Biol Chem 2001;276:31913–18
  • Benedict RG, Schmidt WH, Coghill RD. The stability of penicillin in aqueous solution. J Bacteriol 1946;51:291–2
  • Morris GM, Huey R, Lindstrom W, et al. Autodock4 and AutoDockTools4: automated docking with selective receptor flexibility. J Comput Chem 2009;16:2785–91

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