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Research Article

Expression of heterologous oxalate decarboxylase in HEK293 cells confers protection against oxalate induced oxidative stress as a therapeutic approach for calcium oxalate stone disease

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Pages 426-433 | Received 10 Aug 2016, Accepted 07 Oct 2016, Published online: 24 Jan 2017

References

  • Coe FL, Evan A, Worcester E. Kidney stone disease. J Clin Investig 2005;115:2598–608.
  • Lange JN, Wood KD, Wong H, et al. Sensitivity of human strains of Oxalobacter formigenes to commonly prescribed antibiotics. Urology 2012;79:1286–9.
  • Ye ZQ, Kong DB, Chen ZQ, et al. Stable expression of the oxc and frc genes from Oxalobacter formigenes in human embryo kidney 293 cells: implications for gene therapy of hyperoxaluria. Int J Mol Med 2007;20:521–6.
  • Chen Z, Liu G, Ye Z, et al. The construction of an oxalate-degrading intestinal stem cell population in mice: a potential new treatment option for patients with calcium oxalate calculus. Urol Res 2012;40:131–41.
  • Tanner A, Bornemann S. Bacillus subtilis YvrK is an acid-induced oxalate decarboxylase. J Bacteriol 2000;182:5271–3.
  • Anbazhagan K, George L, Sadasivam S. Heterologous expression of oxalate decarboxylase in Lactobacillus plantarum NC8. Curr Microbiol 2009;58:117–21.
  • Sasikumar P, Gomathi S, Anbazhagan K, et al. Secretion of biologically active heterologous oxalate decarboxylase (OxdC) in Lactobacillus plantarum WCFS1 using homologous signal peptides. Biomed Res Int 2013;2013:280432.
  • Sasikumar P, Gomathi S, Anbazhagan K, et al. Recombinant Lactobacillus plantarum expressing and secreting heterologous oxalate decarboxylase prevents renal calcium oxalate stone deposition in experimental rats. J Biomed Sci 2014; 21:13.
  • Davis D, Hughes C. Dead cell discrimination. In: Living colour, Springer Lab Manuals. Berlin Heidelberg: Springer-Verlag; 2000:372–6.
  • Sinha K. Colorimetric assay of catalase. Anal Biochem 1972;47:389–94.
  • Kakkar P, Das B, Viswanathan PN. A modified spectrophotometric assay of superoxide dismutase. Indian J Biochem Biophys 1984;21:130–2.
  • Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979;95:351–8.
  • Graves JA, Wang Y, Sim-Lucas S, et al. Mitochondrial structure, function and dynamics are temporally controlled by c-Myc. PLoS One 2000;7:e37699.
  • Hegde M, Karki SS, Thomas E, et al. Novel levamisole derivative induces extrinsic pathway of apoptosis in cancer cells and inhibits tumor progression in mice. PloS One 2012;7:e43632.
  • Tian F, Ding D, Li D. Fangchinoline targets PI3K and suppresses PI3K/AKT signaling pathway in SGC7901 cells. Int J Oncol 2015;46:2355–63.
  • Hoppe B, von Unruh G, Laube N, et al. Oxalate degrading bacteria: new treatment option for patients with primary and secondary hyperoxaluria. Urol Res 2005;33:372–5.
  • Poljsak B, Suput D, Milisav I. Achieving the balance between ros and antioxidants: when to use the synthetic antioxidants. Oxid Med Cell Longev 2013;2013:956792.
  • Cao L, Thomas WH, Cooney R, et al. Mitochondrial dysfunction is a primary event in renal cell oxalate toxicity. Kidney Int 2004;66:1890–900.
  • Zhai W, Zheng J, Yao X, et al. Catechin prevents the calcium oxalate monohydrate induced renal calcium crystallization in NRK-52E cells and the ethylene glycol induced renal stone formation in rat. BMC Complement Altern Med 2013;13:228.
  • Farooq SM, Boppana NB, Asokan D, et al. C-phycocyanin confers protection against oxalate-mediated oxidative stress and mitochondrial dysfunctions in MDCK cells. PLoS One 2014;9:e93056.
  • Lee E, Jeong BC, Park YH, Kim HH. Expression of the gene encoding oxalate decarboxylase from Bacillus subtilis and characterization of the recombinant enzyme. BMC Res Notes 2014;7:598.
  • Rashed T, Menon M, Thamilselvan S. Molecular mechanism of oxalate-induced free radical production and glutathione redox imbalance in renal epithelial cells: effect of antioxidants. Am J Nephrol 2004;24:557–68.
  • Tsujihata M, Tsujikawa K, Tei N, et al. Urinary macromolecules and renal tubular cell protection from oxalate injury: comparison of normal subjects and recurrent stone formers. Int J Urol 2006;13:197–201.
  • Khan SR. Reactive oxygen species, inflammation and calcium oxalate nephrolithiasis. Transl Androl Urol 2014;3:256–76.
  • Sharma M, Kaur T, Singla SK. Role of mitochondria and NADPH oxidase derived reactive oxygen species in hyperoxaluria induced nephrolithiasis: therapeutic intervention with combinatorial therapy of N-acetyl cysteine and apocynin. Mitochondrion 2016;27:15–24.
  • Patel AB, Robertson WG, Choong S, Hothersall JS. Heat-shock protein 25 ameliorates calcium oxalate crystal-mediated oxidative stress in renal epithelial cells. BJU Int 2006;98:1094–9.
  • Poljsak B. Strategies for reducing or preventing the generation of oxidative stress. Oxid Med Cell Longev 2011;2011:194586.
  • Zuo J, Khan A, Glenton PA, Khan SR. Effect of NADPH oxidase inhibition on the expression of kidney injury molecule and calcium oxalate crystal deposition in hydroxy-L-proline-induced hyperoxaluria in the male Sprague-Dawley rats. Nephrol Dial Transplant 2011;26:1785–96.