Water permeability is a measure of severity in acute appendicitis

References

• St Peter SD, Tsao K, Spilde TL, et al. Single daily dosing ceftriaxone and metronidazole vs standard triple antibiotic regimen for perforated appendicitis in children: a prospective randomized trial. J Pediatr Surg 2008;43:981–5.
   PubMed Web of Science ®Google Scholar
• Graffeo CS, Counselman FL. Appendicitis. Emerg Med Clin North Am 1996;14:653–71.
   PubMedGoogle Scholar
• Herliczek TW, Swenson DW, Mayo-Smith WW. Utility of MRI after inconclusive ultrasound in pediatric patients with suspected appendicitis: retrospective review of 60 consecutive patients. AJR Am J Roentgenol 2013;200:969–73.
   PubMed Web of Science ®Google Scholar
• Doria AS, Moineddin R, Kellenberger CJ, et al. US or CT for diagnosis of appendicitis in children and adults? A meta-analysis. Radiology 2006;241:83–94.
   PubMed Web of Science ®Google Scholar
• Kulik DM, Uleryk EM, Maguire JL. Does this child have bacterial meningitis? A systematic review of clinical prediction rules for children with suspected bacterial meningitis. J Emerg Med 2013;45:508–19.
   PubMed Web of Science ®Google Scholar
• Zhang S, Du T, Jiang X, Song C. Laparoscopic appendectomy in children with perforated appendicitis: a meta-analysis. Surg Laparosc Endosc Percutan Techniq. 2017. [Epub ahead of print]. doi: 10.1097/SLE.0000000000000411
   Web of Science ®Google Scholar
• Lee SL, Stark R, Yaghoubian A, et al. Does age affect the outcomes and management of pediatric appendicitis? J Pediatr Surg 2011;46:2342–5.
   PubMed Web of Science ®Google Scholar
• Acharya A, Markar SR, Ni M, Hanna GB. Biomarkers of acute appendicitis: systematic review and cost-benefit trade-off analysis. Surg Endosc 2017;31:1022–31.
   PubMed Web of Science ®Google Scholar
• Preston GM, Carroll TP, Guggino WB, Agre P. Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein. Science 1992;256:385–7.
   PubMed Web of Science ®Google Scholar
• Verkman AS. Aquaporins in clinical medicine. Annu Rev Med 2012;63:303–16.
   PubMed Web of Science ®Google Scholar
• Carbrey JM, Agre P. Discovery of the aquaporins and development of the field. Handb Exp Pharmacol 2009;190:3–28.
   PubMedGoogle Scholar
• Meier-Ruge WA, Bruder E. Pathology of chronic constipation in pediatric and adult coloproctology. Pathobiology 2005;72:1–102.
   PubMed Web of Science ®Google Scholar
• Bachmann L, Besendorfer M, Carbon R, et al. Immunohistochemical panel for the diagnosis of Hirschsprung's disease using antibodies to MAP2, calretinin, GLUT1 and S100. Histopathology 2015;66:824–35.
   PubMed Web of Science ®Google Scholar
• Ma T, Hasegawa H, Skach WR, et al. Expression, functional analysis, and in situ hybridization of a cloned rat kidney collecting duct water channel. Am J Physiol 1994;266:C189–97.
   PubMed Web of Science ®Google Scholar
• Echevarria M, Munoz-Cabello AM, Sanchez-Silva R, et al. Development of cytosolic hypoxia and hypoxia-inducible factor stabilization are facilitated by aquaporin-1 expression. J Biol Chem 2007;282:30207–15.
   PubMed Web of Science ®Google Scholar
• Abreu-Rodriguez I, Sanchez Silva R, Martins AP, Soveral G, Toledo-Aral JJ, Lopez-Barneo J, et al. Functional and transcriptional induction of aquaporin-1 gene by hypoxia; analysis of promoter and role of Hif-1alpha. PLoS One 2011;6:e28385.
   PubMed Web of Science ®Google Scholar
• Zhang J, Xiong Y, Lu LX, et al. AQP1 expression alterations affect morphology and water transport in Schwann cells and hypoxia-induced up-regulation of AQP1 occurs in a HIF-1alpha-dependent manner. Neuroscience 2013;252:68–79.
   PubMed Web of Science ®Google Scholar
• Rodriguez-Sanjuan JC, Martin-Parra JI, Seco I, et al. C-reactive protein and leukocyte count in the diagnosis of acute appendicitis in children. Dis Colon Rectum 1999;42:1325–9.
   PubMed Web of Science ®Google Scholar
• Andersson RE. Meta-analysis of the clinical and laboratory diagnosis of appendicitis. Br J Surg 2004;91:28–37.
   PubMed Web of Science ®Google Scholar
• Gao H, He C, Fang X, et al. Localization of aquaporin-1 water channel in glial cells of the human peripheral nervous system. Glia 2006;53:783–7.
   PubMed Web of Science ®Google Scholar
• Nagahama M, Ma N, Semba R, Naruse S. Aquaporin 1 immunoreactive enteric neurons in the rat ileum. Neurosci Lett 2006;395:206–10.
   PubMed Web of Science ®Google Scholar
• Ishihara E, Nagahama M, Naruse S, et al. Neuropathological alteration of aquaporin 1 immunoreactive enteric neurons in the streptozotocin-induced diabetic rats. Autonom Neurosci 2008;138:31–40.
   PubMed Web of Science ®Google Scholar
• Arciszewski MB, Stefaniak M, Zacharko-Siembida A, Calka J. Aquaporin 1 water channel is expressed on submucosal but not myenteric neurons from the ovine duodenum. Ann. Anat 2011;193:81–5.
   PubMed Web of Science ®Google Scholar
• Preston GM, Smith BL, Zeidel ML, et al. Mutations in aquaporin-1 in phenotypically normal humans without functional CHIP water channels. Science 1994;265:1585–7.
   PubMed Web of Science ®Google Scholar
• Detmers FJ, de Groot BL, Muller EM, et al. Quaternary ammonium compounds as water channel blockers. Specificity, potency, and site of action. J Biol Chem 2006;281:14207–14.
   PubMed Web of Science ®Google Scholar
• Brooks HL, Regan JW, Yool AJ. Inhibition of aquaporin-1 water permeability by tetraethylammonium: involvement of the loop E pore region. Mol Pharmacol 2000;57:1021–6.
   PubMed Web of Science ®Google Scholar
• Kourghi M, Pei JV, De Ieso ML, et al. Bumetanide derivatives AqB007 and AqB011 selectively block the Aquaporin-1 ion channel conductance and slow cancer cell migration. Mol Pharmacol 2016;89:133–40.
   PubMed Web of Science ®Google Scholar
• Mola MG, Nicchia GP, Svelto M, et al. Automated cell-based assay for screening of aquaporin inhibitors. Anal Chem 2009;81:8219–29.
   PubMed Web of Science ®Google Scholar