The potential public health impact of the respiratory syncytial virus prefusion F protein vaccine in people aged ≥60 years in Japan: results of a Markov model analysis

References

• Lambert L, Sagfors AM, Openshaw PJ, et al. Immunity to RSV in early-life. Front Immunol. 2014;5:466. doi: 10.3389/fimmu.2014.00466
   PubMed Web of Science ®Google Scholar
• Shi T, Denouel A, Tietjen AK, et al. Global disease burden estimates of respiratory syncytial virus–associated acute respiratory infection in older adults in 2015: a systematic review and meta-analysis. J Infect Dis. 2020;222(Supplement_7):S577–S583. doi: 10.1093/infdis/jiz059
   PubMedGoogle Scholar
• Savic M, Penders Y, Shi T, et al. Respiratory syncytial virus disease burden in adults aged 60 years and older in high-income countries: a systematic literature review and meta-analysis. Influenza Other Respir Viruses. 2023 Jan;17(1):e13031.
   PubMed Web of Science ®Google Scholar
• Nam HH, Ison MG. Respiratory syncytial virus infection in adults. BMJ. 2019;366(I5021):l5021. doi: 10.1136/bmj.l5021
   PubMedGoogle Scholar
• Villanueva DH, Arcega V, Rao M. Review of respiratory syncytial virus infection among older adults and transplant recipients. Ther Adv Infect Dis. 2022 Jan;9:20499361221091413. doi: 10.1177/20499361221091413
   Web of Science ®Google Scholar
• Kurai D, Natori M, Yamada M, et al. Occurrence and disease burden of respiratory syncytial virus and other respiratory pathogens in adults aged ≥65 years in community: a prospective cohort study in Japan. Influenza Resp Viruses. 2022 Mar;16(2):298–307. doi: 10.1111/irv.12928
   PubMed Web of Science ®Google Scholar
• Igarashi A, Togo K, Kobayashi Y, et al. Inpatient and outpatient costs associated with respiratory syncytial virus in Japanese infants and older adults. Future Virol. 2023;18(10):643–657. doi: 10.2217/fvl-2023-0069
   Web of Science ®Google Scholar
• National Institute of Infectious Diseases (NIID). A case of RSV-B outbreak in a nursing home during the new coronavirus epidemic. IASR. 2022;43(4):87–88.
   Google Scholar
• Stephens LM, Varga SM. Considerations for a respiratory syncytial virus vaccine targeting an elderly population. Vaccines (Basel). 2021 Jun 9;9(6):624. doi: 10.3390/vaccines9060624
   PubMed Web of Science ®Google Scholar
• Li Y, Kulkarni D, Begier E, et al. Adjusting for case under-ascertainment in estimating RSV hospitalisation burden of older adults in high-income countries: a systematic review and modelling study. Infect Dis Ther. 2023 Apr;12(4):1137–1149. doi: 10.1007/s40121-023-00792-3
   PubMed Web of Science ®Google Scholar
• McLaughlin JM, Khan F, Begier E, et al. Rates of medically attended RSV among US adults: a systematic review and meta-analysis. Open Forum Infect Dis. 2022 Jul;9(7):ofac300.
   PubMed Web of Science ®Google Scholar
• Belongia EA, King JP, Kieke BA, et al. Clinical features, severity, and incidence of RSV illness during 12 consecutive seasons in a community cohort of adults >/=60 years old. Open Forum Infect Dis. 2018 Dec;5(12):ofy316.
   PubMed Web of Science ®Google Scholar
• Falsey AR, Hennessey PA, Formica MA, et al. Respiratory syncytial virus infection in elderly and high-risk adults. N Engl J Med. 2005;352(17):1749–1759. doi: 10.1056/NEJMoa043951
   PubMed Web of Science ®Google Scholar
• Ackerson B, Tseng HF, Sy LS, et al. Severe morbidity and mortality associated with respiratory syncytial virus versus influenza infection in hospitalized older adults. Clin Infect Dis. 2019 Jul 2;69(2):197–203. doi: 10.1093/cid/ciy991
   PubMed Web of Science ®Google Scholar
• Lee N, Lui GC, Wong KT, et al. High morbidity and mortality in adults hospitalized for respiratory syncytial virus infections. Clin Infect Dis. 2013 Oct;57(8):1069–77.
   PubMed Web of Science ®Google Scholar
• Anderson LJ, Dormitzer PR, Nokes DJ, et al. Strategic priorities for respiratory syncytial virus (RSV) vaccine development. Vaccine. 2013 Apr 18;31(Suppl 2):B209–B215. doi: 10.1016/j.vaccine.2012.11.106
   PubMedGoogle Scholar
• World Health Organization. WHO preferred product characteristics for respiratory syncytial virus (RSV) vaccines. Organization WH, editor. Geneva: Department of Immunization, Vaccines and Biologicals; 2017.
   Google Scholar
• Leroux-Roels I, Davis MG, Steenackers K, et al. Safety and immunogenicity of a respiratory syncytial virus prefusion F (RSVPreF3) Candidate vaccine in older adults: phase 1/2 randomized clinical trial. J Infect Dis. 2023 Mar 28;227(6):761–772. doi: 10.1093/infdis/jiac327
   PubMed Web of Science ®Google Scholar
• GSK. GSK shares positive data for Arexvy, its respiratory syncytial virus (RSV) older adult vaccine, indicating protection over two RSV seasons. 2023 [cited 2023 Jun]. Available from: https://www.gsk.com/en-gb/media/press-releases/gsk-shares-positive-data-for-arexvy-its-respiratory-syncytial-virus-older-adult-vaccine-indicating-protection-over-two-rsv-seasons/
   Google Scholar
• Papi A, Ison MG, Langley JM, et al. Respiratory syncytial virus prefusion F protein vaccine in older adults. N Engl J Med. 2023;388(7):595–608. doi: 10.1056/NEJMoa2209604
   PubMed Web of Science ®Google Scholar
• Colosia A, Costello J, McQuarrie K, et al. Systematic literature review of the signs and symptoms of respiratory syncytial virus. Influenza Other Respir Viruses. 2023 Feb;17(2):e13100.
   PubMed Web of Science ®Google Scholar
• Portal site of Official Statistics of Japan (e-STAT). Estimation of population 2022. [cited 2023 Jun]. Available from: https://www.e-stat.go.jp/stat-search/files?page=1&toukei=00200524&tstat=000000090001
   Google Scholar
• Ison MG, Papi A, Langley JM, et al. editors. Efficacy of one dose of the respiratory syncytial virus (RSV) prefusion F protein vaccine (RSVPreF3 OA) in adults IDWeeK. Boston MA (US): Oxford University Press; 2023.
   Google Scholar
• Tsuzuki S, Yoshihara K. The characteristics of influenza-like illness management in Japan. BMC Public Health. 2020 Apr 28;20(1):568. doi: 10.1186/s12889-020-08603-x
   PubMed Web of Science ®Google Scholar
• Zhang Q, Feng S, Wong IOL, et al. A population-based study on healthcare-seeking behaviour of persons with symptoms of respiratory and gastrointestinal-related infections in Hong Kong. BMC Public Health. 2020 Mar 27;20(1):402. doi: 10.1186/s12889-020-08555-2
   PubMed Web of Science ®Google Scholar
• GSK Data on File. 2023N539973_00.
   Google Scholar
• National Institute of Infectious Diseases. Annual report (2020): sentinel-reporting diseases (monthly) - number of cases and number of cases per sentinel by year, sex, and month. 2020 [cited 2023 Jun]. Available from: https://www.niid.go.jp/niid/images/idwr/ydata/2020/Syuukei/Syu_22_3.xlsx
   Google Scholar
• Takahashi H, Sato Y, Yajima T, editors. #193 diagnostic status and clinical picture of adult RSV infection cases after the COVID-19 pandemic. The 71st Japanese Association for Infectious Diseases East Japan meeting/The 69th Japanese Society of Chemotherapy East Japan branch meeting 2022; Sapporo.
   Google Scholar
• Miyama T, Iritani N, Nishio T, et al. Seasonal shift in epidemics of respiratory syncytial virus infection in Japan. Epidemiol Infect. 2021 Feb 11;149:e55. doi: 10.1017/S0950268821000340
   PubMed Web of Science ®Google Scholar
• Katsurada N, Suzuki M, Aoshima M, et al. The impact of virus infections on pneumonia mortality is complex in adults: a prospective multicentre observational study. BMC Infect Dis. 2017 Dec 6;17(1):755. doi: 10.1186/s12879-017-2858-y
   PubMedGoogle Scholar
• Nguyen-Van-Tam JS, O’Leary M, Martin ET, et al. Burden of respiratory syncytial virus infection in older and high-risk adults: a systematic review and meta-analysis of the evidence from developed countries. Eur Respir Rev. 2022 Dec 31;31(166):220105. doi: 10.1183/16000617.0105-2022
   PubMed Web of Science ®Google Scholar
• Molnar D, La E, Verelst F, editors. 33 - modeling the clinical and economic burden of respiratory syncytial virus (RSV) among adults ≥60 years of age in the United States. A Global Conference on Novel RSV Preventative and Therapeutic Interventions - RSVVW’23 7th ReSViNET Conference; 2023; Lisbon, Portugal: ReSViNET - Respiratory Syncytial Virus Foundation.
   Google Scholar
• Portal site of Official Statistics of Japan (e-STAT). Abridged life tables 2021 2021 [cited 2023 Apr]. Available from: https://www.e-stat.go.jp/stat-search/files?page=1&query=%E7%B0%A1%E6%98%93%E7%94%9F%E5%91%BD%E8%A1%A8&layout=dataset
   Google Scholar
• Ortega Sanchez I Advisory Committee on Immunization Practices (ACIP) held on June 21, 2023. 2023 [cited 2023 Jun]. Available from: http://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2023-06-21-23/05-RSV-Adults-Ortega-Sanchez-508.pdf
   Google Scholar
• Ministry of Health Labour and Welfare (MHLW). The number (%) of those who got vaccinated in the national immunization program [cited 2023 Apr]. Available from: https://www.mhlw.go.jp/topics/bcg/other/5.html
   Google Scholar
• Portal site of official statistics of Japan (e-STAT). Statistics Of Medical Activities In Public Health Insurance 2021. 2021 [cited 2023 Apr]. Available from: https://www.e-stat.go.jp/stat-search/files?page=1&layout=datalist&toukei=00450048&tstat=000001029602&cycle=7&tclass1=000001166295&tclass2=000001166326&tclass3=000001166327&tclass4val=0
   Google Scholar
• Portal site of official statistics of Japan (e-STAT). Patient Survey 2020. 2020 [cited 2023 Apr]. Available from: https://www.e-stat.go.jp/stat-search/files?page=1&layout=datalist&toukei=00450022&tstat=000001031167&cycle=7&tclass1=000001166809&tclass2=000001166811&tclass3=000001166812&tclass4=000001166813&cycle_facet=tclass1%3Acycle&tclass5val=0&metadata=1&data=1
   Google Scholar
• European Centre for Disease Prevention and Control (ECDC). Intensified circulation of respiratory syncitial virus (RSV) and associated hospital burden in the EU/EEA Stockholm 2022. [cited 2023 Jun]. Available from: https://www.ecdc.europa.eu/en/publications-data/intensified-circulation-respiratory-syncytial-virus-rsv-and-associated-hospital
   Google Scholar
• National Institute of Infectious Diseases (NIID). Infectious disease - surveillance. 2023 [cited 2023 Jul]. Available from: https://www.niid.go.jp/niid/en/iasr-e.html
   Google Scholar
• Liu P, Xu M, Lu L, et al. The changing pattern of common respiratory and enteric viruses among outpatient children in Shanghai, China: two years of the COVID-19 pandemic. J Med Virol. 2022 Oct;94(10):4696–4703.
   PubMed Web of Science ®Google Scholar
• Onwuchekwa C, Moreo LM, Menon S, et al. Underascertainment of respiratory syncytial virus infection in adults due to diagnostic testing limitations: a systematic literature review and meta-analysis. J Infect Dis. 2023;228(2):173–184. doi: 10.1093/infdis/jiad012
   PubMed Web of Science ®Google Scholar
• Interac. Japan’s Healthcare System vs The US | Statistics & Cost Comparison. 2023. Available from: https://interacnetwork.com/japans-healthcare-system-vs-the-us-statistics-cost-comparison/#:~:text=Comparative%20statistics,healthy%20lifestyles%2C%20and%20preventing%20disease
   Google Scholar
• Mizumoto K, Chowell G, Simonsen L, et al. The burden of influenza and respiratory syncytial viruses in Japan, 2006–2014: a regionand age-specific excess mortality study. Inter J Infect Dis. 2019;79:1–150. doi: 10.1016/j.ijid.2018.11.241
   PubMed Web of Science ®Google Scholar
• Molnar D, La E, Verelst F, et al. editors. Assessing the public health impact of the adjuvanted respiratory syncytial virus prefusion F protein vaccine among older adults in the United States (US). Boston (US): ISPO RRTI(h)(s); 2023.
   Google Scholar
• Shono A, Hoshi SL, Kondo M. The impact on vaccination coverage following introduction of a routine pneumococcal vaccination programme for the elderly in Japan. Vaccine. 2018 Sep 18;36(39):5886–5890. doi: 10.1016/j.vaccine.2018.08.023
   PubMed Web of Science ®Google Scholar