Effect of l-arginine on blood pressure in pregnancy-induced hypertension: A randomized placebo-controlled trial

References

• Buhimschi I, Yallampalli C, Chwalisz K, Garfield R E. Preeclampsia-like conditions produced by nitric oxide inhibition: Effects of l-arginine, d-arginine and steroid hormones. Hum Reprod 1995; 10: 2723–2730
   PubMed Web of Science ®Google Scholar
• Helmbrecht G D, Farhat M Y, Lochbaum L, Brown H E, Yadgarova K T, Eglinton G S, Ramwell P W. l-Arginine reverses the adverse pregnancy changes induced by nitric oxide synthase inhibition in the rat. Am J Obstet Gynecol 1996; 175: 800–805
   PubMed Web of Science ®Google Scholar
• Alexander B T, Llinas M T, Kruckeberg W C, Granger J P. l-Arginine attenuates hypertension in pregnant rats with reduced uterine perfusion pressure. Hypertension 2004; 43: 832–837
   PubMed Web of Science ®Google Scholar
• Facchinetti F, De Martis S, Neri I, Caputo A S, Volpe A. Effect of transdermal glyceryltrinitrate on 24-h blood pressure changes in patients with gestational hypertension. Prenat Neonat Med 1997; 2: 22–28
   Google Scholar
• Ramsay B, De Belder A, Campbell S, Moncada S, Martins J F. A nitric oxide donor improves uterine artery diastolic blood flow in normal early pregnancy and in women at high risk of preeclampsia. Eur J Clin Invest 1994; 24: 76–78
   PubMed Web of Science ®Google Scholar
• Cetin A, Yurtcu N, Guvenal T, Imir A G, Duran B, Cetin M. The effect of glyceryltrinitrate on hypertension in women with severe preeclampsia, HELLP syndrome, and eclampsia. Hypertens Pregnancy 2004; 23: 37–46
   PubMed Web of Science ®Google Scholar
• Hishikawa K, Nakaki T, Suzuki H, Saruta T, Kato R. l-Arginine-induced hypotension. Lancet 1991; 337: 683
   PubMed Web of Science ®Google Scholar
• Higashi Y, Oshima T, Ozono R, Watanabe M, Matsuura H, Kajiyama G. Effects of l-arginine infusion on renal hemodynamics in patients with mild essential hypertension. Hypertension 1995; 25: 898–902
   PubMed Web of Science ®Google Scholar
• Facchinetti F, Longo M, Piccinini F, Neri I, Volpe A. l-Arginine infusion reduces blood pressure in preeclamptic women through nitric oxide release. J Soc Gynecol Invest 1999; 6: 202–207
   PubMedGoogle Scholar
• Neri I, Marietta M, Piccinini F, Volpe A, Facchinetti F. The l-arginine–nitric oxide system regulates platelet aggregation in pregnancy. J Soc Gynecol Invest 1998; 5: 192–196
   PubMedGoogle Scholar
• Neri I, Mazza V, Galassi M C, Volpe A, Facchinetti F. Effects of l-arginine on utero-placental circulation in growth-retarded fetuses. Acta Obstet Gynecol Scand 1996; 75: 208–212
   PubMed Web of Science ®Google Scholar
• Germain A M, Valdes G, Romanik M C, Reyes M S. Evidence supporting a beneficial role for long-term l-arginine supplementation in high-risk pregnancies. Hypertension 2004; 43: e1
   PubMedGoogle Scholar
• Cunningham F G, Gant N F, Leveno K J, Gilstrap L C, III, Hauth J C, Wenstrom K D. Hypertensive disorders of pregnancy. Williams Obstetrics 21st Edition, F G Cunningham, N F Gant, K J Leveno, L C Gilstrap, III, J C Hauth, K D Wenstrom. McGraw–Hill. 2001; 567–618
   Google Scholar
• Report of the National High Blood Pressure Education Program Working Group on high pressure in pregnancy. Am J Obstet Gynecol 2000; 183: S1–S22
   PubMedGoogle Scholar
• Smulders R A, Aarsen M, Teerlink T, De Vries P MJM, Van Kamp G J, Donker A JM, Stehouwer C DA. Haemodynamic and biochemical response to l-arginine and l-lysine infusion in normal subjects: l-arginine-induced vasodilatation cannot be explained by non-specific effects of cationic amino acids. Clin Sci 1997; 92: 367–374
   Google Scholar
• Lekakis J P, Papathanassiou S, Papaioannou T G, Papamichael C M, Zakopoulos N, Kotsis V, Dagre A G, Stamatelopoulos K, Protogerou A, Stamatelopoulos S F. Oral l-arginine improves endothelial dysfunction in patients with essential hypertension. Int J Cardiol 2002; 86: 317–323
   PubMed Web of Science ®Google Scholar
• Moncada S, Palmer R MJ, Higgs E A. Nitric oxide: Physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991; 43: 109–142
   PubMed Web of Science ®Google Scholar
• Egashira K, Hirooka Y, Kuga T, Mhori M, Takeshita A. Effects of l-arginine supplementation on endothelium-dependent coronary vasodilation in patients with angina pectoris and normal arteriograms. Circulation 1996; 94: 130–134
   PubMed Web of Science ®Google Scholar
• Chauhan A, More R S, Mullins P A, Taylor G, Petch C, Schofield P M. Aging-associated endothelial dysfunction in humans is reversed by l-arginine. J Am Coll cardiol 1996; 28: 1796–1804
   PubMed Web of Science ®Google Scholar
• Grunewald C, Kublickas M, Carlstrom K, Lunell N O, Nisell H. Effects of nitroglycerine on the uterine and umbilical circulation in severe preeclampsia. Obstet Gynecol 1995; 86: 600–604
   PubMed Web of Science ®Google Scholar
• Thaler I, Amit A, Jakobi P, Itskovitz-Eldor J. The effect of isosorbide dinitrate on uterine artery and umbilical artery flow velocity waveforms at mid-pregnancy. Obstet Gynecol 1996; 88: 838–843
   PubMedGoogle Scholar
• Neri I, Valensise H, Facchinetti F, Menghini S, Romanini C, Volpe A. 24-Hour ambulatory blood pressure monitoring: A comparison between transdermal glyceryl-trinitrate and oral nifedipine. Hypertens Pregnancy 1999; 18: 107–113
   PubMed Web of Science ®Google Scholar
• Myatt L, Rosenfield R B, Eis A L, Brockman D E, Greer I, Lyall F. Nitrotyrosine residues in placenta. Evidence of peroxynitrate formation and action. Hypertension 1996; 28: 488–493
   Google Scholar
• Davidge S T. Oxidative stress and altered endothelial cell function in preeclampsia. Semin Reprod Endocrinol 1998; 16: 65–73
   PubMedGoogle Scholar
• Roggensack A M, Zhang Y, Davidge S T. Evidence for peroxynitrite formation in the vasculature of women with preeclampsia. Hypertension 2004; 43: 614–622
   PubMedGoogle Scholar
• Noris M, Todeschini M, Cassis P, Pasta F, Cappellini A, Bonazzola S, Macconi D, Maucci R, Porrati F, Benigni A, et al. l-Arginine depletion in preeclampsia orients nitric oxide synthase toward oxidant species. Hypertension 2004; 43: 614–622
   PubMed Web of Science ®Google Scholar
• Saudan P, Brown M, Budolle M L, Jones M. Does gestational hypertension become pre-eclampsia. Br J Obstet Gynaecol 1998; 105: 1177–1184
   PubMedGoogle Scholar