HCG—A new kid on the block in prematurity prevention

References

• Iams J D, Creasy R K. Preterm labor and delivery. Maternal-fetal medicine: Principles and practice. 5^th ed, R K Creasy, R Resnik, J D Iams. WB Saunders, Philadelphia 2004; 623–662
   Google Scholar
• Ward R M, Beachy J C. Neonatal complications following preterm birth. Br J Obstet Gynecol 2003; 110(Suppl 20)8–16
   Google Scholar
• ACOG Practice Bulletin. Clinical management guidelines for obstetrician-gynecologist. Number 43, May 2003. Management of preterm labor. Obstet Gynecol 2003; 101: 1039–1046
   PubMed Web of Science ®Google Scholar
• Lamont R F, International Preterm Labour Council. Evidence-based labour ward guidelines for the diagnosis, management and treatment of spontaneous preterm labour. J Obstet Gynecol 2003; 23: 469–478
   PubMedGoogle Scholar
• Ingemarson I, Lamont R F. An update on the controversies of tocolytic therapy for the prevention of preterm birth. Acta Obstet Gynecol Scand 2003; 82: 1–9
   PubMedGoogle Scholar
• Martin J A, Hamilton B E, Sutton P D, Ventura S J, Menacker F, Munson M L. Births: Final data from 2002. Natl Vital Stat Rep 2003; 52: 1–113
   PubMedGoogle Scholar
• Filicori M, Fazleabas A T, Huhtaniemi I, Licht P, Rao ChV, Tesarik J, Zygmunt M. Novel concepts of human chorionic gonadotropin: Reproductive system interactions and potential in the management of infertility. Fertil Steril 2005; 84: 275–284
   PubMed Web of Science ®Google Scholar
• Than N G, Itakura A, Rao ChV, Nohira T, Toth P, Mansell J P, Isaka K, Nishi H, Takayama M, Than G N. Clinical application of pregnancy-related proteins—A workshop report. Placenta 2003; 24(Suppl A)S60–64
   Google Scholar
• Charrel-Dennis M, Jackson A M, Lund T, Lapthorn A J, Berger P, Roitt I M, Delves P J. The major hormone-specific discontinuous epitopes on human chorionic gonadotrophin. J Mol Endocrinol 2004; 32: 571–581
   PubMedGoogle Scholar
• Bristow A, Berger P, Bidart J M, Birken S, Norman R, Stenman U H, Sturgeon C, IFCC Working Group on hCG. Establishment, value assignment, and characterization of new WHO reference reagents for six molecular forms of human chorionic gonadotropin. Clin Chem 2005; 51: 177–182
   PubMed Web of Science ®Google Scholar
• Cole L A, Sutton J M. HCG tests in the management of gestational trophoblastic diseases. Clin Obstet Gynecol 2003; 46: 523–540
   PubMedGoogle Scholar
• Reshef E, Lei Z M, Rao C V, Pridham D, Chegini N, Luborski J L. The presence of gonadotropin receptors in nonpregnant human uterus, human placenta, fetal membranes, and decidua. J Clin Endocrinol Metab 1990; 70: 421–430
   PubMed Web of Science ®Google Scholar
• Lin P C, Li X, Lei Z M, Rao ChV. Human cervix contains functional luteinizing hormone/human chorionic gonadotropin receptors. J Clin Endocrinol Metab 2003; 88: 3409–3414
   PubMedGoogle Scholar
• Rao ChV. Physiological and pathological relevance of human uterine LH/hCG receptors—Editorial. J Soc Gynecol Invest 2006; 13: 77–78
   PubMedGoogle Scholar
• Zuo J, Lei Z M, Rao C V. Human myometrial chorionic gonadotropin/luteinizing hormone receptors in preterm and term deliveries. J Clin Endocrinol Metab 1994; 79: 907–911
   PubMed Web of Science ®Google Scholar
• Környei J L, Lei Z M, Rao C V. Human myometrial smooth muscle cells are novel targets on direct regulation by human chorionic gonadotropin. Biol Reprod 1993; 49: 1149–1157
   PubMedGoogle Scholar
• Ambrus G, Rao C V. Novel regulation of pregnant human myometrial smooth muscle cell gap junction by human chorionic gonadotropin. Endocrinology 1994; 135: 2772–2779
   PubMed Web of Science ®Google Scholar
• Eta E, Ambrus G, Rao C V. Direct regulation of human myometrial contractions by human chorionic gonadotropin. J Clin Endocrinol Metab 1994; 79: 1582–1586
   PubMed Web of Science ®Google Scholar
• Lin D X, Lei Z M, Li X, Rao C V. Targeted disruption of LH receptor gene revealed the importance of uterine LH signalling. Mol Cell Endocrinol 2005; 234: 105–116
   PubMedGoogle Scholar
• Mesiano S. Myometrial progesterone responsiveness and the control of human parturition. J Soc Gynecol Invest 2004; 11: 193–202
   PubMedGoogle Scholar
• Meis P J, Connors N. Progesterone treatment to prevent preterm birth. Clin Obstet Gynecol 2004; 47: 784–795
   PubMed Web of Science ®Google Scholar
• Slattery M M, Brennan C, O'Leary M J, Morrison J J. Human chorionic gonadotropin inhibition of pregnant human contractility. Br J Obstet Gynaecol 2001; 108: 704–708
   Google Scholar
• Doheny H C, Houlihan D D, Ravikumar N, Smith T J, Morrison J J. Human chorionic gonadotropin relaxation of human pregnant myometrium and activation of the BKCa channel. J Clin Endocrinol Metab 2003; 88: 4310–4315
   PubMed Web of Science ®Google Scholar
• Matsuzaki N, Li Y, Masuhiro K, Toushun J O, Shimoya K, Taniguchi T, Saji F, Tanizawa O. Trophoblast-derived transforming growth factor-β1 suppresses cytokine-induced, but not gonadotropin releasing hormone-induced, release of human chorionic gonadotropin by normal human trophoblasts. J Clin Endocrinol Metab 1992; 74: 211–216
   PubMedGoogle Scholar
• Tsukihara S, Harada T, Deura I, Mitsunari M, Yoshida S, Iwabe T, Terakawa N. Interleukin-1beta-induced expression of IL-6 and production of human chorionic gonadotropin in human trophoblast cells via nuclear factor-kappaB activation. Am J Reprod Immunol 2004; 52: 218–223
   PubMed Web of Science ®Google Scholar
• Akoum A, Metz C N, Morin M. Marked increase in macrophage migration inhibitory factor synthesis and secretion in human endometrial cells in response to human chorionic gonadotropin hormone. J Clin Endocrinol Metab 2005; 90: 2904–2910
   PubMedGoogle Scholar
• Perrier d'Hauterive S, Charlet-Renard C, Berndt S, Dubois M, Munaut C, Goffin F, Hagelstein M T, Noel A, Hazout A, Foidart J M, et al. Human chorionic gonadotropin and growth factors at the embryonic–endometrial interface control leukaemia inhibitory factor (LIF) and interleukin-6 (IL-6) secretion by human endometrial epithelium. Hum Reprod 2004; 19: 2633–2643
   PubMedGoogle Scholar
• Ietta F, Todros T, Ticconi C, Piccoli E, Zicari A, Piccione E, Paulesu L. Macrophage migration inhibitory factor in human pregnancy and labor. Am J Reprod Immunol 2002; 48: 1–6
   PubMedGoogle Scholar
• Kosaka K, Fujiwara H, Tatsumi K, Yoshioka S, Sato Y, Egawa H, Higuchi T, Nakayama T, Ueda M, Maeda M, Fujii S. Human chorionic gonadotropin (HCG) activates monocytes to produce interleukin-8 via a different pathway from luteinizing hormone/HCG receptor system. J Clin Endocrinol Metab 2002; 87: 5199–5208
   PubMed Web of Science ®Google Scholar
• Elliott C L, Slater D M, Dennes W, Poston L, Bennett P R. Interleukin-8 expression in human myometrium: Changes in relation to labor onset and with gestational age. Am J Reprod Immunol 2000; 43: 272–277
   PubMedGoogle Scholar
• Young A, Thomson A J, Ledingham M, Jordan F, Greer I A, Norman J E. Immunolocalization of proinflammatory cytokines in myometrium, cervix, and fetal membranes during human parturition at term. Biol Reprod 2002; 66: 445–449
   PubMed Web of Science ®Google Scholar
• Zhang Y M, Rao ChV, Lei Z M. Macrophages in human reproductive tissues contain luteinizing hormone/chorionic gonadotropin receptors. Am J Reprod Immunol 2003; 49: 93–100
   PubMedGoogle Scholar
• Bao S, Rai J, Schreiber J. Expression of nitric oxide synthase isoforms in human pregnant myometrium at term. J Soc Gynecol Invest 2002; 9: 351–356
   PubMedGoogle Scholar
• Ticconi C, Belmonte A, Zicari A, Piccione E. Nitric oxide. Signal molecules in animal and human gestation, Paulesu L Ricci. Research Signpost Transworld Research Network, Trivandrum-KeralaIndia 2004; 157–171, Chapter 9
   Google Scholar
• Lin D X, Lei Z M, Rao ChV. Dependence of uterine cyclooxygenase 2 expression on luteinizing hormone signaling. Biol Reprod 2005; 73: 256–260
   PubMedGoogle Scholar
• Belmonte A, Ticconi C, Dolci S, Giorni M, Zicari A, Lenzi A, Jannini E A, Piccione E. Regulation of phosphodiesterase 5 expression and activity in human pregnant and non-pregnant myometrial cells by human chorionic gonadotropin. J Soc Gynecol Invest 2005; 12: 570–577
   PubMedGoogle Scholar
• Buhimschi C S, Garfield R E, Weiner C P, Buhimschi I. The presence and function of phosphodiesterase 5 in the rat myometrium. Am J Obstet Gynecol 2004; 190: 268–274
   PubMedGoogle Scholar
• Kurtzman J T, Spinnato J A, Goldsmith L J, Zimmermann M J, Klem M, Lei Z M, Rao ChV. Human chorionic gonadotropin exhibits potent inhibition of preterm delivery in a small animal model. Am J Obstet Gynecol 1999; 181: 853–857
   PubMedGoogle Scholar
• Phillips R J, Tyson-Capper A J, Bailey J, Robson S C, Europe-Finner G N. Regulation of expression of the chorionic gonadotropin/luteinizing hormone receptor gene in the human myometrium: Involvement of specificity protein-1 (Sp1), Sp3, Sp4, Sp-like proteins, and histone deacetylases. J Clin Endocrinol Metab 2005; 90: 3479–3490
   PubMed Web of Science ®Google Scholar