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Original Article

Pyelonephritis during pregnancy: A cause for an acquired deficiency of protein Z

, , MD, , , , , , , , , , , , , & show all
Pages 629-637 | Received 25 May 2007, Accepted 10 Apr 2008, Published online: 07 Jul 2009

References

  • Gilstrap L C III, Cunningham F G, Whalley P J. Acute pyelonephritis in pregnancy: An anterospective study. Obstet Gynecol 1981; 57: 409–413
  • Wing D A. Pyelonephritis. Clin Obstet Gynecol 1998; 41: 515–526
  • Bubeck R W. Acute pyelonephritis during pregnancy with anuria, septicemia and thrombocytopenia. Del Med J 1968; 40: 143–147
  • Cunningham F G, Morris G B, Mickal A. Acute pyelonephritis of pregnancy: A clinical review. Obstet Gynecol 1973; 42: 112–117
  • Dilworth E E, Ward J V. Bacteremic shock in pyelonephritis and criminal abortion. Obstet Gynecol 1961; 17: 160–167
  • Mabie W C, Barton J R, Sibai B. Septic shock in pregnancy. Obstet Gynecol 1997; 90: 553–561
  • Ventura J E, Villa M, Mizraji R, Ferreiros R. Acute renal failure in pregnancy. Ren Fail 1997; 19: 217–220
  • Pruett K, Faro S. Pyelonephritis associated with respiratory distress. Obstet Gynecol 1987; 69: 444–446
  • Cunningham F G, Lucas M J, Hankins G D. Pulmonary injury complicating antepartum pyelonephritis. Am J Obstet Gynecol 1987; 156: 797–807
  • Cunningham F G, Lucas M J. Urinary tract infections complicating pregnancy. Baillieres Clin Obstet Gynaecol 1994; 8: 353–373
  • Catanzarite V A, Willms D. Adult respiratory distress syndrome in pregnancy: Report of three cases and review of the literature. Obstet Gynecol Surv 1997; 52: 381–392
  • Hill J B, Sheffield J S, McIntire D D, Wendel G D, Jr. Acute pyelonephritis in pregnancy. Obstet Gynecol 2005; 105: 18–23
  • Gando S, Nanzaki S, Sasaki S, Aoi K, Kemmotsu O. Activation of the extrinsic coagulation pathway in patients with severe sepsis and septic shock. Crit Care Med 1998; 26: 2005–2009
  • Esmon C T, Fukudome K, Mather T, Bode W, Regan L M, Stearns-Kurosawa D J, Kurosawa S. Inflammation, sepsis, and coagulation. Haematologica 1999; 84: 254–259
  • Fernandez-Perez E R, Salman S, Pendem S, Farmer J C. Sepsis during pregnancy. Crit Care Med 2005; 33: S286–293
  • Corrigan J J, Jr, Ray W L, May N. Changes in the blood coagulation system associated with septicemia. N Engl J Med 1968; 279: 851–856
  • Hetland O, Brovold A B, Holme R, Gaudernack G, Prydz H. Thromboplastin (tissue factor) in plasma membranes of human monocytes. Biochem J 1985; 228: 735–743
  • Almdahl S M, Osterud B. Experimental Gram-negative septicemia: Thromboplastin generation in mononuclear phagocytes from different anatomical sites. Thromb Res 1987; 47: 37–46
  • Salgado A, Boveda J L, Monasterio J, Segura R M, Mourelle M, Gomez-Jimenez J, Peracaula R. Inflammatory mediators and their influence on haemostasis. Haemostasis 1994; 24: 132–138
  • Semeraro N, Colucci M. Tissue factor in health and disease. Thromb Haemost 1997; 78: 759–764
  • Bouwman J J, Visseren F L, Bosch M C, Bouter K P, Diepersloot R J. Procoagulant and inflammatory response of virus-infected monocytes. Eur J Clin Invest 2002; 32: 759–766
  • Gando S, Kameue T, Matsuda N, Hayakawa M, Morimoto Y, Ishitani T, Kemmotsu O. Imbalances between the levels of tissue factor and tissue factor pathway inhibitor in ARDS patients. Thromb Res 2003; 109: 119–124
  • Idell S, James K K, Levin E G, Schwartz B S, Manchanda N, Maunder R J, Martin T R, McLarty J, Fair D S. Local abnormalities in coagulation and fibrinolytic pathways predispose to alveolar fibrin deposition in the adult respiratory distress syndrome. J Clin Invest 1989; 84: 695–705
  • Bar-Shavit R, Kahn A, Wilner G D, Fenton J W. Monocyte chemotaxis: Stimulation by specific exosite region in thrombin. Science 1983; 220: 728–731
  • Bizios R, Lai L, Fenton J W, Malik A B. Thrombin-induced chemotaxis and aggregation of neutrophils. J Cell Physiol 1986; 128: 485–490
  • Sonne O. The specific binding of thrombin to human polymorphonuclear leucocytes. Scand J Clin Lab Invest 1988; 48: 831–838
  • Drake W T, Issekutz A C. A role for alpha-thrombin in polymorphonuclear leukocyte recruitment during inflammation. Semin Thromb Hemost 1992; 18: 333–340
  • Drake W T, Lopes N N, Fenton J W, Issekutz A C. Thrombin enhancement of interleukin-1 and tumor necrosis factor-alpha induced polymorphonuclear leukocyte migration. Lab Invest 1992; 67: 617–627
  • Naldini A, Carney D H, Bocci V, Klimpel K D, Asuncion M, Soares L E, Klimpel G R. Thrombin enhances T cell proliferative responses and cytokine production. Cell Immunol 1993; 147: 367–377
  • Franchini M, Veneri D, Lippi G. Inflammation and hemostasis: A bidirectional interaction. Clin Lab 2007; 53: 63–67
  • Dery O, Corvera C U, Steinhoff M, Bunnett N W. Proteinase-activated receptors: Novel mechanisms of signaling by serine proteases. Am J Physiol 1998; 274: C1429–1452
  • Coughlin S R. Protease-activated receptors and platelet function. Thromb Haemost 1999; 82: 353–356
  • Coughlin S R. Thrombin signalling and protease-activated receptors. Nature 2000; 407: 258–264
  • Coughlin S R. Protease-activated receptors in vascular biology. Thromb Haemost 2001; 86: 298–307
  • Landis R C. Protease activated receptors: Clinical relevance to hemostasis and inflammation. Hematol Oncol Clin North Am 2007; 21: 103–113
  • Camerer E, Huang W, Coughlin S R. Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa. Proc Natl Acad Sci U S A 2000; 97: 5255–5260
  • Taylor F B, Chang A C, Peer G, Li A, Ezban M, Hedner U. Active site inhibited factor VIIa (DEGR VIIa) attenuates the coagulant and interleukin-6 and -8, but not tumor necrosis factor, responses of the baboon to LD100 Escherichia coli. Blood 1998; 91: 1609–1615
  • Cunningham M A, Romas P, Hutchinson P, Holdsworth S R, Tipping P G. Tissue factor and factor VIIa receptor/ligand interactions induce proinflammatory effects in macrophages. Blood 1999; 94: 3413–3420
  • Siegbahn A. Cellular consequences upon factor VIIa binding to tissue factor. Haemostasis 2000; 30(Suppl 2)41–47
  • Asokananthan N, Graham P T, Fink J, Knight D A, Bakker A J, McWilliam A S, Thompson P J, Stewart G A. Activation of protease-activated receptor (PAR)- 1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells. J Immunol 2002; 168: 3577–3585
  • Ruf W, Riewald M. Tissue factor-dependent coagulation protease signaling in acute lung injury. Crit Care Med 2003; 31: S231–237
  • Carraway M S, Welty-Wolf K E, Miller D L, Ortel T L, Idell S, Ghio A J, Petersen L C, Piantadosi C A. Blockade of tissue factor: Treatment for organ injury in established sepsis. Am J Respir Crit Care Med 2003; 167: 1200–1209
  • Hjortoe G M, Petersen L C, Albrektsen T, Sorensen B B, Norby P L, Mandal S K, Pendurthi U R, Rao L V. Tissue factor–factor VIIa-specific up-regulation of IL-8 expression in MDA-MB-231 cells is mediated by PAR-2 and results in increased cell migration. Blood 2004; 103: 3029–3037
  • Chu A J. Role of tissue factor in thrombosis. Coagulation–inflammation–thrombosis circuit. Front Biosci 2006; 11: 256–271
  • Chi L, Li Y, Stehno-Bittel L, Gao J, Morrison D C, Stechschulte D J, Dileepan K N. Interleukin-6 production by endothelial cells via stimulation of protease-activated receptors is amplified by endotoxin and tumor necrosis factor-alpha. J Interferon Cytokine Res 2001; 21: 231–240
  • Camerer E, Kolsto A B, Prydz H. Cell biology of tissue factor, the principal initiator of blood coagulation. Thromb Res 1996; 81: 1–41
  • Rao L V, Rapaport S I. Activation of factor VII bound to tissue factor: A key early step in the tissue factor pathway of blood coagulation. Proc Natl Acad Sci U S A 1988; 85: 6687–6691
  • ten Cate H, Bauer K A, Levi M, Edgington T S, Sublett R D, Barzegar S, Kass B L, Rosenberg R D. The activation of factor X and prothrombin by recombinant factor VIIa in vivo is mediated by tissue factor. J Clin Invest 1993; 92: 1207–1212
  • Rodgers G M, Shuman M A. Prothrombin is activated on vascular endothelial cells by factor Xa and calcium. Proc Natl Acad Sci U S A 1983; 80: 7001–7005
  • Butenas S, Mann K G. Blood coagulation. Biochemistry (Mosc.) 2002; 67: 3–12
  • Lu G, Broze G J, Jr, Krishnaswamy S. Formation of factors IXa and Xa by the extrinsic pathway: Differential regulation by tissue factor pathway inhibitor and antithrombin III. J Biol Chem 2004; 279: 17 241–17 249
  • Han X, Fiehler R, Broze G J, Jr. Isolation of a protein Z-dependent plasma protease inhibitor. Proc Natl Acad Sci U S A 1998; 95: 9250–9255
  • Han X, Huang Z F, Fiehler R, Broze G J, Jr. The protein Z-dependent protease inhibitor is a serpin. Biochemistry 1999; 38: 11 073–11 078
  • Han X, Fiehler R, Broze G J, Jr. Characterization of the protein Z-dependent protease inhibitor. Blood 2000; 96: 3049–3055
  • Yin Z F, Huang Z F, Cui J, Fiehler R, Lasky N, Ginsburg D, Broze G J, Jr. Prothrombotic phenotype of protein Z deficiency. Proc Natl Acad Sci U S A 2000; 97: 6734–6738
  • Kemkes-Matthes B, Nees M, Kuhnel G, Matzdorff A, Matthes K J. Protein Z influences the prothrombotic phenotype in factor V Leiden patients. Thromb Res 2002; 106: 183–185
  • Martinelli I, Razzari C, Biguzzi E, Bucciarelli P, Mannucci P M. Low levels of protein Z and the risk of venous thromboembolism. J Thromb Haemost 2005; 3: 2817–2819
  • Fedi S, Sofi F, Brogi D, Tellini I, Cesari F, Sestini I, Gazzini A, Comeglio M, Abbate R, Gensini G F. Low protein Z plasma levels are independently associated with acute coronary syndromes. Thromb Haemost 2003; 90: 1173–1178
  • Vasse M, Guegan-Massardier E, Borg J Y, Woimant F, Soria C. Frequency of protein Z deficiency in patients with ischaemic stroke. Lancet 2001; 357: 933–934
  • Koren-Michowitz M, Eting E, Rahimi-Levene N, Garach-Jehoshua O, Volcheck Y, Kornberg A. Protein Z levels and central retinal vein or artery occlusion. Eur J Haematol 2005; 75: 401–405
  • Gris J C, Quere I, Dechaud H, Mercier E, Pincon C, Hoffet M, Vasse M, Mares P. High frequency of protein Z deficiency in patients with unexplained early fetal loss. Blood 2002; 99: 2606–2608
  • Bretelle F, Arnoux D, Shojai R, D'Ercole C, Sampol J, Dignat F, Camoin-Jau L. Protein Z in patients with pregnancy complications. Am J Obstet Gynecol 2005; 193: 1698–1702
  • Paidas M J, Ku D H, Lee M J, Manish S, Thurston A, Lockwood C J, Arkel Y S. Protein Z, protein S levels are lower in patients with thrombophilia and subsequent pregnancy complications. J Thromb Haemost 2005; 3: 497–501
  • Alexander G R, Himes J H, Kaufman R B, Mor J, Kogan M. A United States national reference for fetal growth. Obstet Gynecol 1996; 87: 163–168
  • Prowse C V, Esnouf M P. The isolation of a new warfarin-sensitive protein from bovine plasma. Biochem Soc Trans 1977; 5: 255–256
  • Broze G J, Jr, Miletich J P. Human protein Z. J Clin Invest 1984; 73: 933–938
  • Tabatabai A, Fiehler R, Broze G J, Jr. Protein Z circulates in plasma in a complex with protein Z-dependent protease inhibitor. Thromb Haemost 2001; 85: 655–660
  • Kemkes-Matthes B, Preissner K T, Langenscheidt F, Matthes K J, Muller-Berghaus G. S protein/vitronectin in chronic liver diseases: Correlations with serum cholinesterase, coagulation factor X and complement component C3. Eur J Haematol 1987; 39: 161–165
  • Yurdakok M, Gurakan B, Ozbag E, Vigit S, Dundar S, Kirazli S. Plasma protein Z levels in healthy newborn infants. Am J Hematol 1995; 48: 206–207
  • Al-Shanqeeti A, van Hylckmama V, Berntorp E, Rosendaal F R, Broze G J, Jr. Protein Z and protein Z-dependent protease inhibitor. Determinants of levels and risk of venous thrombosis. Thromb Haemost 2005; 93: 411–413
  • Quack Loetscher K C, Stiller R, Roos M, Zimmermann R. Protein Z in normal pregnancy. Thromb Haemost 2005; 93: 706–709
  • Kusanovic J P, Espinoza J, Romero R, Hoppensteadt D, Nien J K, Kim C J, Erez O, Soto E, Fareed J, Edwin S, et al. Plasma protein Z concentrations in pregnant women with idiopathic intrauterine bleeding and in women with spontaneous preterm labor. J Matern Fetal Med 2007; 20(6)453–463
  • Lichy C, Kropp S, Dong-Si T, Genius J, Dolan T, Hampe T, Stoll F, Reuner K, Grond-Ginsbach C, Grau A. A common polymorphism of the protein Z gene is associated with protein Z plasma levels and with risk of cerebral ischemia in the young. Stroke 2004; 35: 40–45
  • Miletich J P, Broze G J, Jr. Human plasma protein Z antigen: Range in normal subjects and effect of warfarin therapy. Blood 1987; 69: 1580–1586
  • Vossen C Y, Hasstedt S J, Rosendaal F R, Callas P W, Bauer K A, Broze G J, Hoogendoorn H, Long G L, Scott B T, Bovill E G. Heritability of plasma concentrations of clotting factors and measures of a prethrombotic state in a protein C-deficient family. J Thromb Haemost 2004; 2: 242–247
  • Kemkes-Matthes B, Matthes K J. Protein Z deficiency: A new cause of bleeding tendency. Thromb Res 1995; 79: 49–55
  • Gamba G, Bertolino G, Montani N, Spedini P, Balduini C L. Bleeding tendency of unknown origin and protein Z levels. Thromb Res 1998; 90: 291–295
  • Chaiworapongsa T, Espinoza J, Yoshimatsu J, Kim Y M, Bujold E, Edwin S, Yoon B H, Romero R. Activation of coagulation system in preterm labor and preterm premature rupture of membranes. J Matern Fetal Neonatal Med 2002; 11: 368–373
  • Chaiworapongsa T, Yoshimatsu J, Espinoza J, Kim Y M, Berman S, Edwin S, Yoon B H, Romero R. Evidence of in vivo generation of thrombin in patients with small-for-gestational-age fetuses and pre-eclampsia. J Matern Fetal Neonatal Med 2002; 11: 362–367
  • Naccasha N, Gervasi M T, Chaiworapongsa T, Berman S, Yoon B H, Maymon E, Romero R. Phenotypic and metabolic characteristics of monocytes and granulocytes in normal pregnancy and maternal infection. Am J Obstet Gynecol 2001; 185: 1118–1123
  • Levi M, van der Poll T, Buller H R. Bidirectional relation between inflammation and coagulation. Circulation 2004; 109: 2698–2704
  • Levi M, van der Poll T. Two-way interactions between inflammation and coagulation. Trends Cardiovasc Med 2005; 15: 254–259
  • Cavanagh D, Rao P S. Septic shock (endotoxic shock). Clin Obstet Gynecol 1973; 16: 25–39
  • Ozge-Anwar A H, Freedman J J, Senyi A F, Cerskus A L, Blajchman M A. Enhanced prothrombin-converting activity and factor Xa binding of platelets activated by the alternative complement pathway. Br J Haematol 1984; 57: 221–228
  • Pawlinski R, Mackman N. Tissue factor, coagulation proteases, and protease-activated receptors in endotoxemia and sepsis. Crit Care Med 2004; 32: S293–297
  • Mackman N. Role of tissue factor in hemostasis, thrombosis, and vascular development. Arterioscler Thromb Vasc Biol 2004; 24: 1015–1022
  • Semeraro N, Lattanzio A, Montemurro P, Papanice M, De Lucia O, De Bellis G, Giordano D. Mechanisms of blood clotting activation in inflammation: The role of mononuclear phagocytes. Int J Tissue React 1985; 7: 313–320
  • Oeth P, Parry G C, Mackman N. Regulation of the tissue factor gene in human monocytic cells. Role of AP-1, NF-kappa B/Rel, and Sp1 proteins in uninduced and lipopolysaccharide-induced expression. Arterioscler Thromb Vasc Biol 1997; 17: 365–374
  • Heyderman R S, Klein N J, Daramola O A, Hammerschmidt S, Frosch M, Robertson B D, Levin M, Ison C A. Induction of human endothelial tissue factor expression by Neisseria meningitidis: The influence of bacterial killing and adherence to the endothelium. Microb Pathog 1997; 22: 265–274
  • Levi M, van der Poll T, ten Cate H. Tissue factor in infection and severe inflammation. Semin Thromb Hemost 2006; 32: 33–39
  • Ahamed J, Ruf W. Protease-activated receptor 2-dependent phosphorylation of the tissue factor cytoplasmic domain. J Biol Chem 2004; 279: 23 038–23 044
  • Esmon C T. The interactions between inflammation and coagulation. Br J Haematol 2005; 131: 417–430
  • Arias F, Rodriquez L, Rayne S C, Kraus F T. Maternal placental vasculopathy and infection: Two distinct subgroups among patients with preterm labor and preterm ruptured membranes. Am J Obstet Gynecol 1993; 168: 585–591
  • Arias F, Victoria A, Cho K, Kraus F. Placental histology and clinical characteristics of patients with preterm premature rupture of membranes. Obstet Gynecol 1997; 89: 265–271
  • Welty-Wolf K E, Carraway M S, Ortel T L, Ghio A J, Idell S, Egan J, Zhu X, Jiao J A, Wong H C, Piantadosi C A. Blockade of tissue factor–factor X binding attenuates sepsis-induced respiratory and renal failure. Am J Physiol Lung Cell Mol Physiol 2006; 290: L21–31
  • Busch G, Seitz I, Steppich B, Hess S, Eckl R, Schomig A, Ott I. Coagulation factor Xa stimulates interleukin-8 release in endothelial cells and mononuclear leukocytes: Implications in acute myocardial infarction. Arterioscler Thromb Vasc Biol 2005; 25: 461–466
  • Daubie V, Cauwenberghs S, Senden N H, Pochet R, Lindhout T, Buurman W A, Heemskerk J W. Factor Xa and thrombin evoke additive calcium and proinflammatory responses in endothelial cells subjected to coagulation. Biochim Biophys Acta 2006; 1763(8)860–869
  • Kemkes-Matthes B, Matthes K J. Protein Z. Semin Thromb Hemost 2001; 27: 551–556
  • Richani K, Soto E, Romero R, Espinoza J, Chaiworapongsa T, Nien J K, Edwin S, Kim Y M, Hong J S, Mazor M. Normal pregnancy is characterized by systemic activation of the complement system. J Matern Fetal Neonatal Med 2005; 17: 239–245
  • Soto E, Richani K, Romero R, Espinoza J, Chaiworapongsa T, Nien J K, Edwin S, Kim Y M, Hong J S, Goncalves L, et al. Increased concentration of the complement split product C5a in acute pyelonephritis during pregnancy. J Matern Fetal Neonatal Med 2005; 17: 247–252
  • Ikeda K, Nagasawa K, Horiuchi T, Tsuru T, Nishizaka H, Niho Y. C5a induces tissue factor activity on endothelial cells. Thromb Haemost 1997; 77: 394–398
  • Sitrin R G, Kaltreider H B, Ansfield M J, Webster R O. Procoagulant activity of rabbit alveolar macrophages. Am Rev Respir Dis 1983; 128: 282–287
  • White B, Perry D. Acquired antithrombin deficiency in sepsis. Br J Haematol 2001; 112: 26–31
  • Martinez M A, Pena J M, Fernandez A, Jimenez M, Juarez S, Madero R, Vazquez J J. Time course and prognostic significance of hemostatic changes in sepsis: Relation to tumor necrosis factor-alpha. Crit Care Med 1999; 27: 1303–1308
  • Nawroth P P, Stern D M. Modulation of endothelial cell hemostatic properties by tumor necrosis factor. J Exp Med 1986; 163: 740–745
  • Eckle I, Seitz R, Egbring R, Kolb G, Havemann K. Protein C degradation in vitro by neutrophil elastase. Biol Chem Hoppe Seyler 1991; 372: 1007–1013
  • Madden R M, Ward M, Marlar R A. Protein C activity levels in endotoxin-induced disseminated intravascular coagulation in a dog model. Thromb Res 1989; 55: 297–307
  • de Boer K, ten Cate J W, Sturk A, Borm J J, Treffers P E. Enhanced thrombin generation in normal and hypertensive pregnancy. Am J Obstet Gynecol 1989; 160: 95–100
  • Yuen P M, Yin J A, Lao T T. Fibrinopeptide A levels in maternal and newborn plasma. Eur J Obstet Gynecol Reprod Biol 1989; 30: 239–244
  • Sorensen J D, Secher N J, Jespersen J. Perturbed (procoagulant) endothelium and deviations within the fibrinolytic system during the third trimester of normal pregnancy. A possible link to placental function. Acta Obstet Gynecol Scand 1995; 74: 257–261
  • Walker M C, Garner P R, Keely E J, Rock G A, Reis M D. Changes in activated protein C resistance during normal pregnancy. Am J Obstet Gynecol 1997; 177: 162–169
  • Bellart J, Gilabert R, Miralles R M, Monasterio J, Cabero L. Endothelial cell markers and fibrinopeptide A to D-dimer ratio as a measure of coagulation and fibrinolysis balance in normal pregnancy. Gynecol Obstet Invest 1998; 46: 17–21

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