298
Views
10
CrossRef citations to date
0
Altmetric
Original Article

Amino acid and acylcarnitine profiles in perinatal asphyxia: a case-control study

, , &
Pages 1462-1469 | Received 06 Mar 2017, Accepted 11 Apr 2017, Published online: 05 May 2017

References

  • Volpe JJ. Perinatal brain injury: from pathogenesis to neuro-protection. Ment Retard Dev Disabil Res Rev. 2001;7:56–64.
  • Antonucci R, Porcella A, Pilloni MD. Perinatal asphyxia in the term newborn. J Pediatr Neonat Individual Med. 2014;3:e030269.
  • Kurinczuk JJ, White-Koning M, Badawi N. Epidemiology of neonatal encephalopathy and hypoxic-ischaemic encephalopathy. Early Hum Dev. 2010;86:329–338.
  • Wall SN, Lee AC, Carlo W, et al. Reducing intrapartum-related neonatal deaths in low- and middle-income countries – what works? Semin Perinatol. 2010;34:395–407.
  • Papile L. American Academy of Pediatrics, Committee on Fetus and Newborn, 2012–2013. Clinical Report. Hypothermia and neonatal encephalopathy. Pediatrics. 2014;133:1146–1150.
  • American College of Obstetricians and Gynecologists Task Force and American Academy of Pediatrics. Neonatal encephalopathy and cerebral palsy: defining the pathogenesis and pathophysiology. Washington (DC): ACOG; 2003. p. 1–85. Chapter VIII: Criteria required to define an acute intrapartum hypoxic event as sufficient to cause cerebral palsy.
  • Shalak LF, Laptook AR, Velaphi SC, et al. Amplitude-integrated electroencephalography coupled with an early neurologic examination enhances prediction of term infants at risk for persistent encephalopathy. Pediatrics. 2003;111:351–357.
  • Ferriero DM, Bonifacio SL. The search continues for the elusive biomarkers of neonatal brain injury. J Pediatr. 2014;164:438–440.
  • Fanos V, Barberini L, Antonucci R, et al. Metabolomics in neonatology and pediatrics. Clin Biochem. 2011;44:452–454.
  • Denihan NM, Boylan GB, Murray DM. Metabolomic profiling in perinatal asphyxia: a promising new field. BioMed Res Int. 2015;2015:254076.
  • Sarnat HB, Sarnat MS. Neonatal encephalopathy following fetal distress. A clinical and electroencephalographic study. Arch Neurol. 1976;33:696–705.
  • Xia J, Mandal R, Sinelnikov I, et al. MetaboAnalyst 2.0-a comprehensive server for metabolomic data analysis. Nucleic Acids Res. 2012;40:W127–W133.
  • Ng PC, Lam HS. Biomarkers in neonatology: the next generation of tests. Neonatology. 2012;102:145–151.
  • Wani TA, Zargar S. New ultra-performance liquid chromatography-tandem mass spectrometry method for the determination of irbesartan in human plasma. J Food Drug Analysis. 2015;23:569–576.
  • Koulman A, Prentice P, Wong MCY, et al. The development and validation of a fast and robust dried blood spot based lipid profiling method to study infant metabolism. Metabolomics. 2014;10:1018–1025.
  • Solberg R, Enot D, Deigner H, et al. Metabolomic analyses of plasma reveals new insights into asphyxia and resuscitation in pigs. PLoS One. 2010;5:e9606.
  • Skappak C, Regush S, Cheung PY, et al. Identifying hypoxia in a newborn piglet model using urinary NMR metabolomic profiling. PLoS One. 2013;8:e65035.
  • Murgia F, Noto A, Iacovidou N, et al. Is the quickness of resuscitation after hypoxia influenced by the oxygen concentration? Metabolomics in piglets resuscitated with different oxygen concentrations. J Pediatr Neonat Individual Med. 2013;2:e020233.
  • van Walsum AV, Jongsma HW, Wevers RA, et al. Hypoxia in fetal lambs: a study with (1)H-MNR spectroscopy of cerebrospinal fluid. Pediatr Res. 2001;49:698–704.
  • Hagberg H, Thornberg E, Blennow M, et al. Excitatory amino acids in the cerebrospinal fluid of asphyxiated infants: relationship to hypoxic-ischemic encephalopathy. Acta Paediatr. 1993;82:925–929.
  • Walsh BH, Broadhurst DI, Mandal R, et al. The metabolomic profile of umbilical cord blood in neonatal hypoxic ischaemic encephalopathy. PLoS One. 2012;7:e50520.
  • Sachse D, Solevåg AL, Berg JP, et al. The role of plasma and urine metabolomics in identifying new biomarkers in severe newborn asphyxia: a study of asphyxiated newborn pigs following cardiopulmonary resuscitation. PLoS One. 2016;11:e0161123.
  • Meyburg J, Schulze A, Kohlmuller D, et al. Postnatal changes in neonatal acylcarnitine profile. Pediatr Res. 2001;49:125–129.
  • Fanos V, Barberini L, Antonucci R, et al. Pharma-metabolomics in neonatology: is it a dream or a fact? Curr Pharm Des. 2012;18:2996–3006.
  • Fanos V, Noto A, Xanthos T, et al. Metabolomics network characterization of resuscitation after normocapnic hypoxia in a newborn piglet model supports the hypothesis that room air is better. Biomed Res Int. 2014;2014:731620.
  • Liu XR, Zheng XF, Ji SZ, et al. Metabolomic analysis of thermally injured and/or septic rats. Burns. 2010;36:992–998.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.