Current understanding of autoantibody against angiotensin II type 1 receptor in preeclampsia

References

• Brown MA, Magee LA, Kenny LC, et al. Hypertensive disorders of pregnancy: ISSHP classification, diagnosis, and management recommendations for international practice. Hypertension. 2018;72(1):24–43.
   PubMed Web of Science ®Google Scholar
• Burton GJ, Redman CW, Roberts JM, et al. Pre-eclampsia: pathophysiology and clinical implications. BMJ. 2019;366:1–15.
   Google Scholar
• de Brito Alves JL, de Oliveira Y, Carvalho NNC, et al. Gut microbiota and probiotic intervention as a promising therapeutic for pregnant women with cardiometabolic disorders: present and future directions. Pharmacol Res. 2019;145:104252.
   PubMed Web of Science ®Google Scholar
• Sircar M, Thadhani R, Karumanchi SA. Pathogenesis of preeclampsia. Curr Opin Nephrol Hypertens. 2015;24(2):131–138.
   PubMed Web of Science ®Google Scholar
• Wallukat G, Homuth V, Fischer T, et al. Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptor. J Clin Invest. 1999;103(7):945–952.
   PubMed Web of Science ®Google Scholar
• Yang X, Wang F, Lau WB, et al. Autoantibodies isolated from preeclamptic patients induce endothelial dysfunction via interaction with the angiotensin II AT1 receptor. Cardiovasc Toxicol. 2014;14(1):21–29.
   PubMed Web of Science ®Google Scholar
• Herse F, LaMarca B. Angiotensin II type 1-Receptor Autoantibody (AT1-AA) -mediated pregnancy hypertension. Am J Reprod Immunol. 2013;69(4):1–8.
   PubMed Web of Science ®Google Scholar
• Dechend R, Homuth V, Wallukat G, et al. Agonistic antibodies directed at the angiotensin II, AT1 receptor in preeclampsia. J Soc Gynecol Investig. 2006;13(2):79–86.
   PubMedGoogle Scholar
• Cunningham MW, Castillo J, Ibrahim T, et al. AT1-AA (angiotensin II type 1 receptor agonistic autoantibody) blockade prevents preeclamptic symptoms in placental ischemic rats. Hypertension. 2018;71(5):886–893.
   PubMed Web of Science ®Google Scholar
• LaMarca B, Parrish M, Ray LF, et al. Hypertension in response to autoantibodies to the angiotensin II type i receptor (AT1-AA) in pregnant rats: role of endothelin-1. Hypertension. 2009;54(4):905–909.
   PubMed Web of Science ®Google Scholar
• Lamarca B, Wallace K, Granger J. Role of angiotensin II type i receptor agonistic autoantibodies (AT1-AA) in preeclampsia. Curr Opin Pharmacol. 2011;11(2):175–179.
   PubMed Web of Science ®Google Scholar
• Dhillion P, Wallace K, Herse F, et al. IL-17-mediated oxidative stress is an important stimulator of AT1-AA and hypertension during pregnancy. Am J Physiol Regul Integr Comp. 2012;303(4):R353–R358.
   PubMed Web of Science ®Google Scholar
• Yang X, Wang F, Chang H, et al. Autoantibody against AT1 receptor from preeclamptic patients induces vasoconstriction through angiotensin receptor activation. J Hypertens. 2008;26(8):1629–1635.
   PubMed Web of Science ®Google Scholar
• Irani RA, Xia Y. The functional role of the renin-angiotensin system in pregnancy and preeclampsia. Placenta. 2008;29(9):763–771.
   PubMed Web of Science ®Google Scholar
• Fu MLX, Leung PS, Wallukat G, et al. Agonist-like activity of antibodies to angiotensin II receptor subtype 1 (AT1) from rats immunized with AT1 receptor peptide. Blood Press. 1999;8(5–6):317–324.
   PubMed Web of Science ®Google Scholar
• Wallukat G, Neichel D, Nissen E, et al. Agonistic autoantibodies directed against the angiotensin II AT1 receptor in patients with preeclampsia. Can J Physiol Pharmacol. 2003;81(2):79–83.
   PubMed Web of Science ®Google Scholar
• Abadir PM, Jain A, Powell LJ, et al. Discovery and validation of agonistic angiotensin receptor autoantibodies as biomarkers of adverse outcomes. Circulation. 2017;135(5):449–459.
   PubMed Web of Science ®Google Scholar
• Brouwers L, van der Meiden-van Roest AJ, Savelkoul C, et al. Recurrence of pre-eclampsia and the risk of future hypertension and cardiovascular disease: a systematic review and meta-analysis. Int J Obstetri Gynaecol. 2018;125(13):1642–1654.
   PubMed Web of Science ®Google Scholar
• Zhang S, Zhang X, Yang L, et al. Increased susceptibility to metabolic syndrome in adult offspring of angiotensin type 1 receptor autoantibody-positive rats. Antioxid Redox Signal. 2012;17(5):733–743.
   PubMed Web of Science ®Google Scholar
• Stepan H, Wallukat G, Schultheiss H-P, et al. Is parvovirus B19 the cause for autoimmunity against the angiotensin II type receptor? J Reprod Immunol. 2007;73(2):130–134.
   PubMed Web of Science ®Google Scholar
• Chaiworapongsa T, Chaemsaithong P, Yeo L, et al. Pre-eclampsia part 1: current understanding of its pathophysiology. Nat Rev Nephrol. 2014;10(8):466–480.
   PubMed Web of Science ®Google Scholar
• Parrish MR, Murphy SR, Rutland S, et al. The effect of immune factors, tumor necrosis factor-α, and agonistic autoantibodies to the angiotensin II type i receptor on soluble fms-like tyrosine-1 and soluble endoglin production in response to hypertension during pregnancy. Am J Hypertens. 2010;23(8):911–916.
   PubMed Web of Science ®Google Scholar
• Walther T, Stepan H. Agonist autoantibodies against the angiotensin AT1 receptor in renal and hypertensive disorders. Curr Hypertens Rep. 2007;9(2):128–132.
   PubMed Web of Science ®Google Scholar
• Xia Y, Kellems RE. Angiotensin receptor agonistic autoantibodies and hypertension : preeclampsia and beyond. Circ Res. 2013;113(1):78–87.
   PubMed Web of Science ®Google Scholar
• Song L, Zhang S-L, Bai K-H, et al. Serum agonistic autoantibodies against type-1 angiotensin II receptor titer in patients with epithelial ovarian cancer: a potential role in tumor cell migration and angiogenesis. J Ovarian Res. 2013;6(1):22.
   PubMedGoogle Scholar
• LaMarca B, Wallukat G, Llinas M, et al. Autoantibodies to the angiotensin type I receptor in response to placental ischemia and tumor necrosis factor α in pregnant rats. Hypertension. 2008;52(6):1168–1172.
   PubMed Web of Science ®Google Scholar
• Lamarca B, Parrish MR, Wallace K. Agonistic autoantibodies to the angiotensin II type i receptor cause pathophysiologic characteristics of preeclampsia. Gend Med. 2012;9(3):139–146.
   PubMedGoogle Scholar
• Takimoto E, Ishida J, Sugiyama F, et al. Hypertension induced in pregnant mice by placental renin and maternal angiotensinogen. Science. 1996;274(5289):995–998.
   PubMed Web of Science ®Google Scholar
• Dechend R, Gratze P, Wallukat G, et al. Agonistic autoantibodies to the AT1 receptor in a transgenic rat model of preeclampsia. Hypertension. 2005;45(4):742–746.
   PubMed Web of Science ®Google Scholar
• LaMarca B, Speed J, Ray LF, et al. Hypertension in response to IL-6 during pregnancy: role of AT1-receptor activation. Int J Interferon Cytokine Mediat Res. 2011;2011(3):65–70.
   PubMedGoogle Scholar
• Herse F, Lamarca B. Angiotensin II Type 1 Receptor Autoantibody (AT1-AA)-mediated pregnancy hypertension. Am J Reprod Immunol. 2013;69(4):413–418.
   PubMed Web of Science ®Google Scholar
• Dechend R, Homuth V, Wallukat G, et al. AT(1) receptor agonistic antibodies from preeclamptic patients cause vascular cells to express tissue factor. Circulation. 2000;101(20):2382–2387.
   PubMed Web of Science ®Google Scholar
• Xia Y, Wen H, Bobst S. Bobst MD Maternal autoantibodies from preeclamptic patients activate angiotensin receptors on human trophoblast cells. J Soc Gynecol Investig. 2003;10(2):82–93.
   PubMedGoogle Scholar
• Dechend R, Viedt C, Müller DN, et al. AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidase. Circulation. 2003;107(12):1632–1639.
   PubMed Web of Science ®Google Scholar
• Siddiqui AH, Irani RA, Blackwell SC, et al. Angiotensin receptor agonistic autoantibody is highly prevalent in preeclampsia: correlation with disease severity. Hypertension. 2010;55(2):386–393.
   PubMed Web of Science ®Google Scholar
• Zhou CC, Zhang Y, Irani RA, et al. Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice. Nat Med. 2008;14(8):855–862.
   PubMed Web of Science ®Google Scholar
• Zhou CC, Irani RA, Dai Y, et al. Autoantibody-mediated IL-6-dependent endothelin-1 elevation underlies pathogenesis in a mouse model of preeclampsia. J Immunol. 2011;186(10):6024–6034.
   PubMed Web of Science ®Google Scholar
• Irani RA, Zhang Y, Zhou CC, et al. Autoantibody-mediated angiotensin receptor activation contributes to preeclampsia through tumor necrosis factor-alpha signaling. Hypertension. 2010;55(5):1246–1253.
   PubMed Web of Science ®Google Scholar
• Siddiqui AH, Irani RA, Zhang Y, et al. Recombinant vascular endothelial growth factor 121 attenuates autoantibody-induced features of pre-eclampsia in pregnant mice. Am J Hypertens. 2011;24(5):606–612.
   PubMed Web of Science ®Google Scholar
• Dechend R, Müller DN, Wallukat G, et al. Activating auto-antibodies against the AT1 receptor in preeclampsia. Autoimmun Rev. 2005;4(1):61–65.
   PubMed Web of Science ®Google Scholar
• Elliott SE, Parchim NF, Liu C, et al. Characterization of antibody specificities associated with preeclampsia. Hypertension. 2014;63(5):1086–1093.
   PubMed Web of Science ®Google Scholar
• Wenzel K, Rajakumar A, Haase H, et al. Angiotensin II type 1 receptor antibodies and increased angiotensin II sensitivity in pregnant rats. Hypertension. 2011;58(1):77–84.
   PubMed Web of Science ®Google Scholar
• Thway TM, Shlykov SG, Day M-CC, et al. Antibodies from preeclamptic patients stimulate increased intracellular Ca2+ mobilization through angiotensin receptor activation. Circulation. 2004;110(12):1612–1619.
   PubMed Web of Science ®Google Scholar
• Brewer J, Liu R, Lu Y, et al. Endothelin-1, oxidative stress, and endogenous angiotensin II: mechanisms of angiotensin II type i receptor autoantibody-enhanced renal and blood pressure response during pregnancy. Hypertension. 2013;62(5):886–892.
   PubMed Web of Science ®Google Scholar