208
Views
3
CrossRef citations to date
0
Altmetric
Research Article

Gestational age-specific hematological patterns in preterm infants following necrotizing enterocolitis

ORCID Icon, , , , &
Pages 10093-10102 | Received 09 Mar 2022, Accepted 12 Jul 2022, Published online: 04 Sep 2022

References

  • Neu J, Walker WA. Necrotizing enterocolitis. N Engl J Med. 2011;364(3):255–264.
  • Sankaran K, Puckett B, Lee DS, et al. Variations in incidence of necrotizing enterocolitis in Canadian neonatal intensive care units. J Pediatr Gastroenterol Nutr. 2004;39(4):366–372.
  • Sjoberg Bexelius T, Ahle M, Elfvin A, et al. Intestinal failure after necrotising enterocolitis: incidence and risk factors in a Swedish population-based longitudinal study. BMJ Paediatr Open. 2018;2(1):e000316.
  • Allin BSR, Long AM, Gupta A, British Association of Paediatric Surgeons Congenital Anomalies Surveillance System Necrotising Enterocolitis Collaboration, et al. One-year outcomes following surgery for necrotising enterocolitis: a UK-wide cohort study. Arch Dis Child Fetal Neonatal Ed. 2018;103(5):F461–f466.
  • Knell J, Han SM, Jaksic T, et al. Current status of necrotizing enterocolitis. Curr Probl Surg. 2019;56(1):11–38.
  • Stoll BJ, Hansen NI, Bell EF, Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network, et al. Trends in care practices, morbidity, and mortality of extremely preterm neonates, 1993–2012. JAMA. 2015;314(10):1039–1051.
  • Santulli TV, Schullinger JN, Heird WC, et al. Acute necrotizing enterocolitis in infancy: a review of 64 cases. Pediatrics. 1975;55(3):376–387.
  • Mowitz ME, Dukhovny D, Zupancic JAF. The cost of necrotizing enterocolitis in premature infants. Semin Fetal Neonatal Med. 2018;23(6):416–419.
  • Ganapathy V, Hay JW, Kim JH, et al. Long term healthcare costs of infants who survived neonatal necrotizing enterocolitis: a retrospective longitudinal study among infants enrolled in Texas Medicaid. BMC Pediatr. 2013;13(1):127.
  • Kurscheid T, Holschneider AM. Necrotizing enterocolitis (NEC) – mortality and long-term results. Eur J Pediatr Surg. 1993;3(3):139–143.
  • Thakkar HS, Lakhoo K. The surgical management of necrotising enterocolitis (NEC). Early Hum Dev. 2016;97:25–28.
  • Raval MV, Moss RL. Current concepts in the surgical approach to necrotizing enterocolitis. Pathophysiology. 2014;21(1):105–110.
  • Rees CM, Hall NJ, Eaton S, et al. Surgical strategies for necrotising enterocolitis: a survey of practice in the United Kingdom. Arch Dis Child Fetal Neonatal Ed. 2005;90(2):F152–F155.
  • Hutter JJ Jr, Hathaway WE, Wayne ER. Hematologic abnormalities in severe neonatal necrotizing enterocolitis. J Pediatr. 1976;88(6):1026–1031.
  • Ragazzi S, Pierro A, Peters M, et al. Early full blood count and severity of disease in neonates with necrotizing enterocolitis. Pediatr Surg Int. 2003;19(5):376–379.
  • Patel CC. Hematologic abnormalities in acute necrotizing enterocolitis. Pediatr Clin North Am. 1977;24(3):579–584.
  • Kenton AB, ODonovan D, Cass DL, et al. Severe thrombocytopenia predicts outcome in neonates with necrotizing enterocolitis. J Perinatol. 2005;25(1):14–20.
  • Ververidis M, Kiely EM, Spitz L, et al. The clinical significance of thrombocytopenia in neonates with necrotizing enterocolitis. J Pediatr Surg. 2001;36(5):799–803.
  • Maheshwari A. Immunologic and hematological abnormalities in necrotizing enterocolitis. Clin Perinatol. 2015;42(3):567–585.
  • Lambert DK, Christensen RD, Baer VL, et al. Fulminant necrotizing enterocolitis in a multihospital healthcare system. J Perinatol. 2012;32(3):194–198.
  • Cremer M, Sola-Visner M, Roll S, et al. Platelet transfusions in neonates: practices in the United States vary significantly from those in Austria, Germany, and Switzerland. Transfusion. 2011;51(12):2634–2641.
  • Patel RM, Josephson CD, Shenvi N, et al. Platelet transfusions and mortality in necrotizing enterocolitis. Transfusion. 2019;59(3):981–988.
  • Kenton AB, Hegemier S, Smith EO, et al. Platelet transfusions in infants with necrotizing enterocolitis do not lower mortality but may increase morbidity. J Perinatol. 2005;25(3):173–177.
  • Curley A, Stanworth SJ, Willoughby K, PlaNeT2 MATISSE Collaborators, et al. Randomized trial of platelet-transfusion thresholds in neonates. N Engl J Med. 2019;380(3):242–251.
  • MohanKumar K, Namachivayam K, Song T, et al. A murine neonatal model of necrotizing enterocolitis caused by anemia and red blood cell transfusions. Nat Commun. 2019;10(1):3494.
  • Patel RM, Knezevic A, Shenvi N, et al. Association of red blood cell transfusion, anemia, and necrotizing enterocolitis in very low-birth-weight infants. JAMA. 2016;315(9):889–897.
  • Garg P, Pinotti R, Lal CV, et al. Transfusion-associated necrotizing enterocolitis in preterm infants: an updated meta-analysis of observational data. J Perinat Med. 2018;46(6):677–685.
  • Garg PM, Ravisankar S, Bian H, et al. Relationship between packed red blood cell transfusion and severe form of necrotizing enterocolitis: a case control study. Indian Pediatr. 2015;52(12):1041–1045.
  • Garg PM, O'Connor A, Ansari MAY, et al. Hematological predictors of mortality in neonates with fulminant necrotizing enterocolitis. J Perinatol. 2021;41(5):1110–1121.
  • MohanKumar K, Kaza N, Jagadeeswaran R, et al. Gut mucosal injury in neonates is marked by macrophage infiltration in contrast to pleomorphic infiltrates in adult: evidence from an animal model. Am J Physiol Gastrointest Liver Physiol. 2012;303(1):G93–G102.
  • Remon J, Kampanatkosol R, Kaul RR, et al. Acute drop in blood monocyte count differentiates NEC from other causes of feeding intolerance. J Perinatol. 2014;34(7):549–554.
  • Hyman PE, Abrams CE, Zipser RD. Enhanced urinary immunoreactive thromboxane in neonatal necrotizing enterocolitis. A diagnostic indicator of thrombotic activity. Am J Dis Child. 1987;141(6):686–689.
  • Hsueh W, Caplan MS, Qu XW, et al. Neonatal necrotizing enterocolitis: clinical considerations and pathogenetic concepts. Pediatr Dev Pathol. 2003;6(1):6–23.
  • Namachivayam K, MohanKumar K, Shores DR, et al. Targeted inhibition of thrombin attenuates murine neonatal necrotizing enterocolitis. Proc Natl Acad Sci USA. 2020;117(20):10958–10969.
  • Namachivayam K, MohanKumar K, Garg L, et al. Neonatal mice with necrotizing enterocolitis-like injury develop thrombocytopenia despite increased megakaryopoiesis. Pediatr Res. 2017;81(5):817–824.
  • Cremer M, Weimann A, Szekessy D, et al. Low immature platelet fraction suggests decreased megakaryopoiesis in neonates with sepsis or necrotizing enterocolitis. J Perinatol. 2013;33(8):622–626.
  • Cekmez F, Tanju IA, Canpolat FE, et al. Mean platelet volume in very preterm infants: a predictor of morbidities? Eur Rev Med Pharmacol Sci. 2013;17(1):134–137.
  • Wang YC, Chan OW, Chiang MC, et al. Red blood cell transfusion and clinical outcomes in extremely low birth weight preterm infants. Pediatr Neonatol. 2017;58(3):216–222.
  • Moore SW, Arnold M, Wright C. Necrotizing enterocolitis and the placenta – a key etiological link. J Pediatr Surg. 2013;48(2):359–362.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.