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Research Article

B-cell-activating factor (BAFF) and platelet-activating factor (PAF) in pregnancies complicated by maternal obesity and diabetes: a preliminary study

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Article: 2272010 | Received 03 Jul 2023, Accepted 12 Oct 2023, Published online: 23 Oct 2023

References

  • American College of Obstetricians and Gynecologists. ACOG Committee opinion no. 549: obesity in pregnancy. Obstet Gynecol. 2013;121(1):213–217.
  • Pantham P, Aye ILMH, Powell TL. Inflammation in maternal obesity and gestational diabetes mellitus. Placenta. 2015;36(7):709–715. doi: 10.1016/j.placenta.2015.04.006.
  • Renault KM, Norgaard K, Nilas L, et al. The treatment of obese pregnant women (TOP) study: a randomized controlled trial of the effect of physical activity intervention assessed by pedometer with or without dietary intervention in obese pregnant women. Am J Obstet Gynecol. 2014;210(2):134.e1–134.e9. doi: 10.1016/j.ajog.2013.09.029.
  • World Health Organization. WHO report. 2022. Available from: http://www.who.int/mediacentre/factsheets/fs311/en/
  • Poston L, Caleyachetty R, Cnattingius R, et al. Preconceptional and maternal obesity: epidemiology and health consequences. Lancet Diabetes Endocrinol. 2016;4(12):1025–1036. doi: 10.1016/S2213-8587(16)30217-0.
  • Neri C, Di Cesare C, Labianca A, et al. Obesity in pregnancy as a model to identify women at risk for later metabolic syndrome. Gynecol Endocrinol. 2018;34(1):28–31. doi: 10.1080/09513590.2017.1342792.
  • Jones CW. Gestational diabetes and its impact on the neonate. Neonatal Netw. 2001;20(6):17–23. doi: 10.1891/0730-0832.20.6.17.
  • Hales CN, Barker DJ. Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. 1992. Int J Epidemiol. 2013;42(5):1215–1222. doi: 10.1093/ije/dyt133.
  • Krakowiak P, Walker CK, Bremer AA, et al. Maternal metabolic conditions and risk for autism and other neurodevelopmental disorders. Pediatrics. 2012;129(5):e1121–e1128. doi: 10.1542/peds.2011-2583.
  • Huda SS, Brodie LE, Sattar N. Obesity in pregnancy: prevalence and metabolic consequences. Semin Fetal Neonatal Med. 2010;15(2):70–76. doi: 10.1016/j.siny.2009.09.006.
  • Taddei S, Ghiadoni L, Salvetti G, et al. Obesity and endothelial dysfunction. G Ital Cardiol (Rome). 2006;7(11):715–723.
  • Gregor MF, Hotamisligil GS. Inflammatory mechanisms in obesity. Annu Rev Immunol. 2011;29(1):415–445. doi: 10.1146/annurev-immunol-031210-101322.
  • Aye IL, Lager S, Ramirez VI, et al. Increasing maternal body mass index is associated with systemic inflammation in the mother and the activation of distinct placental inflammatory pathways. Biol Reprod. 2014;90(6):129.
  • Kleiblova P, Dostalova I, Bartlova M, et al. Expression of adipokines and estrogen receptors in adipose tissue and placenta of patients with gestational diabetes mellitus. Mol Cell Endocrinol. 2010;314(1):150–156. doi: 10.1016/j.mce.2009.08.002.
  • Hauguel-de Mouzon S, Guerre-Millo M. The placenta cytokine network and inflammatory signals. Placenta. 2006;27(8):794–798.
  • Jansson N, Rosario FJ, Gaccioli F, et al. Activation of placental mTOR signaling and amino acid transporters in obese women giving birth to large babies. J Clin Endocrinol Metab. 2013;98(1):105–113. doi: 10.1210/jc.2012-2667.
  • Jansson T, Ekstrand Y, Bjorn C, et al. Alterations in the activity of placental amino acid transporters in pregnancies complicated by diabetes. Diabetes. 2002;51(7):2214–2219. doi: 10.2337/diabetes.51.7.2214.
  • Jones HN, Jansson T, Powell TL. IL-6 stimulates system A amino acid transporter activity in trophoblast cells through STAT3 and increased expression of SNAT2. Am J Physiol Cell Physiol. 2009;297(5):C1228–C1235. doi: 10.1152/ajpcell.00195.2009.
  • Jones HN, Woollett LA, Barbour N, et al. High-fat diet before and during pregnancy causes marked up-regulation of placental nutrient transport and fetal overgrowth in C57/BL6 mice. FASEB J. 2009;23(1):271–278. doi: 10.1096/fj.08-116889.
  • Jarvie E, Hauguel-de-Mouzon S, Nelson SM, et al. Lipotoxicity in obese pregnancy and its potential role in adverse pregnancy outcome and obesity in the offspring. Clin Sci. 2010;119(3):123–129. doi: 10.1042/CS20090640.
  • Piuri G, Basello K, Rossi G, et al. Methylglyoxal, glycated albumin, PAF, and TNF-α: possible inflammatory and metabolic biomarkers for management of gestational diabetes. Nutrient. 2020;12(2):479. doi: 10.3390/nu12020479.
  • Cappelletti M, Tognon E, Vona L, et al. Specific serum IgG and symptom reduction with a personalized, unrestricted-calorie diet of six weeks in irritable bowel syndrome (IBS). Nutr Metab. 2020;17(1):101. doi: 10.1186/s12986-020-00528-x.
  • Speciani AF, Piuri G. Measuring biomarkers for an innovative personal food profile. J Am Coll Nutr. 2015;34(Suppl 1):34–38. doi: 10.1080/07315724.2015.1080109.
  • Schneider P, MacKay F, Steiner V, et al. BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth. J Exp Med. 1999;189(11):1747–1756. doi: 10.1084/jem.189.11.1747.
  • Sutherland APR, Mackay F, Mackay CR, et al. Targeting BAFF: immunomodulation for autoimmune diseases and lymphomas. Pharmacol Ther. 2006;112(3):774–786. doi: 10.1016/j.pharmthera.2006.06.002.
  • Cheema GS, Roschke V, Hilbert DM, et al. Elevated serum B-lymphocyte stimulator levels in patients with systemic immune based rheumatic diseases. Arthritis Rheum. 2001;44(6):1313–1319. doi: 10.1002/1529-0131(200106)44:6<1313::AID-ART223>3.0.CO;2-S.
  • Ritterhouse LL, Crowe SR, Niewold TB, et al. B lymphocyte stimulator levels in systemic lupus erythematosus: higher circulating levels in African American patients and increased production after influenza vaccination in patients with low baseline levels. Arthritis Rheum. 2011;63(12):3931–3941. doi: 10.1002/art.30598.
  • Fabris M, Visentini D, De Re V, et al. Elevated b cell-activating factor of the tumour necrosis factor family in coeliac disease. Scand J Gastroenterol. 2007;42(12):1434–1439. doi: 10.1080/00365520701452225.
  • Steri M, Orrù V, Idda ML, et al. Overexpression of the cytokine BAFF and autoimmunity risk. N Engl J Med. 2017;376(17):1615–1626. doi: 10.1056/NEJMoa1610528.
  • Kim YH, Choi BH, Cheon HG, et al. B cell activation factor (BAFF) is a novel adipokine that links obesity and inflammation. Exp Mol Med. 2009;41(3):208–216. PMID: 19293640. PMC2679246. doi: 10.3858/emm.2009.41.3.024.
  • Upton JEM, Grunebaum E, Sussman G, et al. Platelet activating factor PAF: a mediator of inflammation. Biofactors. 2022;48(6):1189–1202. PMID 36029481 doi: 10.1002/biof.1883.
  • Ashraf MA, Nookala V. Biochemistry of platelet activating factor. Treasure Island (FL): StatPearls Publishing; 2022.
  • Yamaguchi M, Matsui M, Higa R, et al. A platelet-activating factor (PAF) receptor deficiency exacerbates diet-induced obesity but PAF/PAF receptor signaling does not contribute to the development of obesity-induced chronic inflammation. Biochem Pharmacol. 2015;93(4):482–495. doi: 10.1016/j.bcp.2014.12.022.
  • Filgueiras LR, Koga MM, Quaresma PG, et al. PAFR in adipose tissue macrophages is associated with anti-inflammatory phenotype and metabolic homeostasis. Clin Sci. 2016;130(8):601–612. doi: 10.1042/CS20150538.
  • Kang SA, Keener AB, Jones SZ, et al. IgG-immune complexes promote B cell memory by inducing BAFF. J Immunol. 2016;196(1):196–206. doi: 10.4049/jimmunol.1402527.
  • Gao Q, He G-L, Zhang L, et al. Activity and distribution of plasma platelet-activating factor acetylhydrolase in women with gestational diabetes mellitus and their neonates. Diabetes Metab Res Rev. 2016;32(6):634–642. doi: 10.1002/dmrr.2782.
  • Derbent A, Kargili A, Koca C, et al. Serum platelet-activating factor acetylhydrolase activity: relationship with metabolic syndrome in women with history of gestational diabetes mellitus. Gynecol Endocrinol. 2011;27(2):128–133. doi: 10.3109/09513590.2010.487612.
  • Mackay F, Schneider P. Cracking the BAFF code. Nat Rev Immunol. 2009;9(7):491–502. PMID: 19521398 doi: 10.1038/nri2572.
  • Liu S, Miao J-J, Zhou X, et al. High levels of thyroid hormones promote recurrence of Graves’ disease via overexpression of B-cell-activating factor. J Clin Lab Anal. 2022;36(10):e24701. PMID: 36097969 PMCID: PMC9550970 doi: 10.1002/jcla.24701.
  • Lin JD, Wang YH, Fang WF, et al. Serum BAFF and thyroid autoantibodies in autoimmune thyroid disease. Clin Chim Acta. 2016;462:96–102. PMID: 27616625 doi: 10.1016/j.cca.2016.09.004.
  • Lane LC, Allinson KR, Campbell K, et al. Analysis of BAFF gene polymorphisms in UK graves’ disease patients. Clin Endocrinol. 2019;90(1):170–174. PMID: 30281845 doi: 10.1111/cen.13872.
  • Vannucchi G, Covelli D, Currò N, et al. Serum BAFF concentrations in patients with Graves’ disease and orbitopathy before and after immunosuppressive therapy. J Clin Endocrinol Metab. 2012;97(5):E755–E759. PMID: 22399512. doi: 10.1210/jc.2011-2614.
  • Campi I, Tosi D, Rossi S, et al. B cell activating factor (BAFF) and BAFF receptor expression in autoimmune and nonautoimmune thyroid diseases. Thyroid. 2015;25(9):1043–1049. PMID: 26214745 doi: 10.1089/thy.2015.0029.
  • Arslan Lied G, Lillestøl K, Valeur J, et al. Intestinal B cell-activating factor: an indicator of non-IgE-mediated hypersensitivity reactions to food? Aliment Pharmacol Ther. 2010;32(1):66–73. PMID20353497 doi: 10.1111/j.1365-2036.2010.04314.x.
  • Gu L, Yang J, Gong Y, et al. Lower free thyroid hormone levels are associated with high blood glucose and insulin resistance; these normalize with metabolic improvement of type 2 diabetes. J Diabetes. 2021;13(4):318–329. PMID: 32981234 doi: 10.1111/1753-0407.13118.