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Review

Rapid molecular diagnostics for multi-drug resistant tuberculosis in India

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Pages 197-204 | Received 08 Oct 2017, Accepted 05 Feb 2018, Published online: 12 Feb 2018

References

  • Boehme CC, Nabeta P, Hillemann D, et al. Rapid molecular detection of tuberculosis and rifampin resistance. N Engl J Med 2010; 24(11):1005–1015.
  • Ehsani S, Van den Boom M, Gilpin C, et al. The role of novel molecular techniques for tuberculosis diagnostics in the WHO European region. J Med Microb Diagn 2015; S3: 006.
  • World Health Organisation. Rapid implementation of the Xpert MTB/RIF diagnosis test. Technical and operational “How to” practical considerations. World Health Organization; WHO/HTM/TB/20112. WHO, Geneva, 2014.
  • World Health Organisation. Global Tuberculosis Report 2017. Geneva: World Health Organization; 2017.
  • World Health Organisation. WHO/global fund workshop reaching the “missing million” through scaling up public-private mix for TB care and control in “high-impact”. Asia Meeting Report, WHO/HTM/TB/2014.25; 2014 Jun 25–27; New Delhi, India.
  • Central TB Division. 2017. TB India. Central TB Division, Directorate General of Health Services, Ministry of Health and Family Welfare, Government of India, New Delhi.
  • Jain A, Singh PK, Chooramani G, et al. Drug resistance and associated genetic mutations among patients with suspected MDR-TB in Uttar Pradesh, India. Int J Tuberc Lung Dis 2016; 20(7):870–875.
  • Gilpin C, Korobitsyn A, Weyer K, et al. Current tools available for the diagnosis of drug-resistant tuberculosis. Ther Adv Infect Dis 2016, Vol. 3(6) 145–151
  • World Health Organisation. Xpert MTB/RIF assay for diagnosis of pulmonary and extrapulmonary TB in adults and children. Policy update. WHO/HTM/TB/2013.16. Geneva: World Health Organization; 2013.
  • Steingart KR, Schiller I, Horne DJ, et al. Xpert® Mtb/Rif assay for pulmonary tuberculosis and rifampicin resistance in adults. Cochrane Database Syst Rev. 2014 Jan 21; (1): 1–166.
  • Lawn SD, Zumla AI. Diagnosis of extrapulmonary tuberculosis using the Xpert® MTB/RIF assay. Expert Rev Anti Infect Ther. 2012 Jun; 10(6): 631–635.
  • Kambli P, Ajbani K, Sadani M, et al. Defining multidrug-resistant tuberculosis: Correlating genotype MTBDRplus assay results with minimum inhibitory concentrations. Diagn Microbiol Infect Dis 2015;82(1):49–53.
  • World Health Organization. WHO treatment guidelines for drug-resistant tuberculosis. Geneva: WHO, 2016
  • Nair D, Navneethapandian PD, Tripathy JP, et al. Impact of rapid molecular diagnostic tests on time to treatment initiation and outcomes in patients with multidrug-resistant tuberculosis, Tamil Nadu, India. Trans R Soc Trop Med Hyg 2016; 110(9): 534–541.
  • Singh UB, Pandey P, Mehta G, et al. (2016) Genotypic, phenotypic and clinical validation of GeneXpert in extra-pulmonary and pulmonary tuberculosis in India. PLoS ONE 11(2): e0149258.
  • Rufail SB, Singh S, Singh A, et al. Performance of Xpert MTB/RIF on ascitic fluid samples for detection of abdominal tuberculosis. J Lab Physicians. 2017 Jan-Mar; 9(1): 47–52.
  • Schumacher SG, Nabeta P, Boehme CC, et al. A multicenter diagnostic accuracy study of the Xpert Ultra for tuberculosis diagnosis. Conference Retroviruses Oppor Infect; 2017 Feb 13–16; Seattle, WA.
  • Nair C Overview of technological platforms: Molbio. Oral presentation at: Critical Path to TB Drug Regimens Workshop; 2016 Apr 4–7; Washington, DC.
  • Nikam C, Kazi M, Nair C, et al. Evaluation of the Indian TrueNAT micro RT-PCR device with GeneXpert for case detection of pulmonary tuberculosis. Int J Mycobacteriol. 2014 Sep;3(3):205–210. doi: 10.1016/j.ijmyco.2014.04.003
  • Erica Lessem. The tuberculosis diagnostics pipeline. Treatment Action Group; 2017. (Pipeline report).
  • Tomasicchio M, Theron G, Pietersen E, et al. The diagnostic accuracy of the MTBDRplus and MTBDRsl assays for drug-resistant TB detection when performed on sputum and culture isolates. Sci Rep 2016; (6): 17850.
  • Raizada N, Sachdeva KS, Chauhan DS, et al. A multi-site validation in India of the line probe assay for the rapid diagnosis of multi-drug resistant tuberculosis directly from sputum specimens. PLoS ONE 2014; 9(2):e88626. DOI:10.1371/journal.pone.0088626
  • Sharma SK, Kohli M, Yadav RN, et al. (2015) Evaluating the diagnostic accuracy of Xpert MTB/RIF assay in pulmonary tuberculosis. PLoS ONE 10(10): e0141011. doi:10.1371/journal.pone.0141011
  • Manson AL, Abeel T, Galagan JE, et al. Mycobacterium tuberculosis whole genome sequences from Southern India suggest novel resistance mechanisms and the need for region specific diagnostics. Clin Infect Dis 2017;64(11):1494–1501.
  • Singla N, Satyanarayana S, Sachdeva KS, et al. Impact of introducing the line probe assay on time to treatment initiation of MDR-TB in Delhi, India. PLoS ONE 2014; 9(7): e102989.
  • Yacoob FL, Jose BP, Devi S, et al. 2016d. Primary multidrug resistant tuberculosis and utility of line probe assay for its detection in smear-positive sputum samples in a tertiary care hospital in South India. J Pathog 2016; ID 6235618, 8. https://www.hindawi.com/journals/jpath/2016/6235618/
  • Arora J, Singhal R, Bhalla M, et al. Drug resistance detection and mutation patterns of multidrug resistant tuberculosis strains from children in Delhi. J Epidemiol Glob Health 2016; 7(2):141–145.
  • Bhirud P, Joshi A, Hirani N, et al. Rapid laboratory diagnosis of pulmonary tuberculosis. Int J Mycobacteriol 2017; 3(3): 296–301.
  • Catanzaro A, Rodwell TC, Catanzaro DG, et al. Performance comparison of three rapid tests for the diagnosis of drug-resistant tuberculosis. PLoS ONE 2015; 10(8): e0136861. doi:10.1371/journal.pone.0136861.
  • Dave P, Patel P, Mod B, et al. Evaluation of use of line probe assay on smear-positive direct specimen from extra-pulmonary tuberculosis site. Indian J Tuberc 2015; 62(4): 218–221.
  • Kumar P, Balooni V, Sharma BK, et al. High degree of multi-drug resistance and hetero-resistance in pulmonary TB patients from Punjab state of India. Tuberculosis (Edinb) 2013; 94 (1): 73–80.
  • Kumar P, Balooni V, Singh S. Genetic mutations associated with rifampicin and isoniazid resistance in MDR-TB patients in North-West India. Int J Tuberc Lung Dis 2015; 19(4): 434–439.
  • Madhuri K, Deshpande S, Dharmashale S, et al. Utility of line probe assay for the early detection of multidrug-resistant pulmonary tuberculosis. J Glob Infect Dis 2015; 7(2): 60–65.
  • Singhal R, Myneedu VP, Arora J, et al. Detection of multi-drug resistance & characterization of mutations in Mycobacterium tuberculosis isolates from north-eastern states of India using GenoType MTBDRplus assay. Indian J Med Res 2014; 140(4): 501–506.
  • Singhal R, Singla N, Myneedu VP, et al. Multidrug-resistant tuberculosis among different types of suspected cases: study from New Delhi. Indian J Tuberc 2015; 62 (3): 183–186.
  • Tripathi R, Anupurba S Multidrug-resistant tuberculosis detection and characterization of mutations in mycobacterium tuberculosis by genotype MTBDRplus. Indian J Pathol Microbiol 2017; 60(2):239–242.
  • Tripathi R, Sinha P, Kumari R, et al. Detection of rifampicin resistance in tuberculosis by molecular methods: a report from eastern Uttar Pradesh, India. Indian J Med Microbiol 2016;34:92–94
  • Tripathy S, Kumar R, Singh D. Prevalence of multidrug resistant pulmonary tuberculosis in north Bihar. J Clin Diagn Res 2015; 9(11): LC09–LC12.
  • Vashistha H, Hanif M, Saini S, et al. Rapid detection of extensively drug-resistant (XDR-TB) strains from multidrug-resistant tuberculosis (MDR-TB) cases isolated from smear-negative pulmonary samples in an Intermediate Reference Laboratory in India. Indian J Tuberc 2016; 63(3): 144–148.
  • Sharma SK, Chaubey J, Singh BK, et al. Drug resistance patterns among extra-pulmonary tuberculosiscases in a tertiary care centre in North India. Int J Tuberc Lung Dis. 2017 Oct 1;21(10):1112–1117. doi: 10.5588/ijtld.16.0939
  • Kaviyil JE, Ravikumar R. Diagnosis of tuberculous meningitis: current scenario from a tertiary neurocare centre in India. Indian J Tuberc 2017; 64(3):183–188. Epub 2017. doi: 10.1016/j.ijtb.2017.01.005.
  • Desikan P, Panwalkar N, Mirza SB, et al. Line probe assay for detection of Mycobacterium tuberculosis complex: an experience from Central India. Indian J Med Res 2017; 145: 70–73.
  • World Health Organsiation. Molecular line-probe assay for the detection of resistance to Second-Line Anti-Tb Drugs (SL-LPA). World Health Organsiation, Geneva, Switzerland; 2016; http://www.who.int/tb/publications/factsheet_tb_sllpa.pdf
  • World Health Organization. Tuberculosis laboratory biosafety manual 2012. World Health Organization, Geneva, Switzerland. . WHO/HTM/TB/2012.11
  • National Centre for Disease Control. Biosafety manual for public health laboratories. New Delhi: Directorate General of Health Services Ministry of Health and Family Welfare; 2016. Available from: http://www.ncdc.gov.in/writereaddata/mainlinkfile/File608.pdf
  • Global Laboratory Initiative. Model TB diagnostic algorithms. Global Laboratory Initiative. 2017. Available from: http://www.stoptb.org/wg/gli/assets/documents/GLI_algorithms.pdf
  • Shah I, Gupta Y. Role of molecular tests for diagnosis of tuberculosis in children. Pediatric Oncall 2015 (1): 12. http://www.pediatriconcall.com/pediatric-journal/View/fulltext-articles/923/J/0/0/485/0
  • Sachdeva KS, Raizada N, Sreenivas A, et al. Use of Xpert MTB/RIF in decentralized public health settings and its effect on pulmonary TB and DR-TB case finding in India. Plos One 2015; 10: e0126065
  • Rupert S, Vassall A, Raizada N, et al. Bottom-up or top-down: unit cost estimation of tuberculosis diagnostic tests in India. Int J Tuberc Lung Dis 2017; 21(4):375–380.
  • Khaparde S, Raizada N, Nair SA, et al. (2017) Scaling-up the Xpert MTB/RIF assay for the detection of tuberculosis and rifampicin resistance in India: an economic analysis. PLoS ONE 12(9): e0184270.
  • Vassall A, van Kampen S, Sohn H, et al. (2011) Rapid diagnosis of tuberculosis with the Xpert MTB/RIF assay in high burden countries: a cost-effectiveness analysis. PLoS Med 8(11): e1001120.
  • Shah M, Chihota V, Coetzee G, et al. Comparison of laboratory costs of rapid molecular tests and conventional diagnostics for detection of tuberculosis and drug-resistant tuberculosis in South Africa. BMC Infect Dis 2013; 13:352
  • Bajinka O, Secka O. Integration of molecular methods into microbiological diagnostics. Appli Micro Open Access 2017; 3(1) 130: 1–6.
  • Pantoja A, Fitzpatrick C, Vassall A, et al. Xpert MTB/RIF for diagnosis of tuberculosis and drug-resistant tuberculosis: a cost and affordability analysis. Eur Respir J 2013 42: 708–720
  • Frick M, Lessem E, McKenna L. Diagnostics, treatment, prevention and vaccines in development (Tuberculosis edition). London: HIV i-Base/Treatment Action Group; 2016.

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