1,434
Views
1
CrossRef citations to date
0
Altmetric
Editorial

The effect of sustained virological response by direct-acting antivirals on insulin resistance and diabetes mellitus in patients with chronic hepatitis C

ORCID Icon, , &
Pages 595-597 | Received 06 Mar 2018, Accepted 24 Jul 2018, Published online: 01 Aug 2018

References

  • Adinolfi LE, Restivo L, Zampino R, et al. Metabolic alterations and chronic hepatitis C: treatment strategies. Expert Opin Pharmacother. 2011;12:2215–2234.
  • Lonardo A, Adinolfi LE, Petta S, et al. Hepatitis C and diabetes: the inevitable coincidence? Expert Review Anti-Infect Ther. 2009;7:239–308.
  • Miyamoto H, Moriishi K, Moriya K, et al. Involvement of the PA28gamma-dependent pathway in insulin resistance induced by hepatitis C virus core protein. J Virol. 2007;81:1727–1735.
  • Masini M, Campani D, Boggi U, et al. Hepatitis C virus infection and human pancreatic beta-cell dysfunction. Diabetes Care. 2005;28:940–941.
  • Aytug S, Reich D, Sapiro LE, et al. Impaired IRS-1/PI3-kinase signaling in patients with HCV: a mechanism for increased prevalence of type 2 diabetes. Hepatology. 2005;38:1384–1392.
  • Pandya P, Pant C, Taylor R, et al. Impact of sustained virological response to chronic hepatitic C antiviral therapy on new onset diabetes mellitus type 2 after controlling for metabolic syndrome. J Investig Med. 2017;65:765–771.
  • Adinolfi LE, Nevola R, Guerrera B, et al. HCV clearance by direct-acting antiviral treatment and impact on insulin resistance in chronic hepatitis C. J Gastroenterol Hepatol. 2018;33:1379–1382.
  • Li J, Zhang T, Gordon SC, et al. Impact of sustained virological response on incidence of type 2 diabetes in hepatitis C patients. Hepatology. 2017;66:531A.
  • Hum J, Jou JH, Green PK, et al. Improvement in glycemic control of type 2 diabetes after successful treatment of hepatitis C virus. Diabetes Care. 2017;40:1173–1180.
  • Ciancio A, Bosio R, Bo S, et al. Significant improvement of glycemic control in diabetic patients with HCV infection responding to direct-acting antiviral agents. J Med Virol. 2018;90:320–327.
  • Dawood AA, Nooh MZ, Elgamal AA. Factors associated with improved glycemic control by direct-acting antiviral agent treatment in Egyptian type 2 diabetes mellitus patients with chronic hepatitis C genotype 4. Diabetes Metab J. 2017;41:316–321.
  • Pavone P, Tieghi T, d’Ettorre G, et al. Rapid decline of fasting glucose in HCV diabetic patients treated with direct-acting antiviral agents. Clin Microbiol Infect. 2016;22:462.e1–462.e3.
  • Morales AL, Junga Z, Singla MB, et al. Hepatitis C eradication with sofosbuvir leads to significant metabolic changes. World J Hepatol. 2016;8:1557–1563.
  • Fabrizio C, Procopio A, Scudeller L, et al. HCV and diabetes: towards a ‘sustained’ glycaemic improvement after treatment with DAAs? Clin Microbiol Infect. 2017;23:342–343.
  • Abdel Alem S, Elsharkawy A, Fouad R, et al. Improvement of glycemic state among responders to sofosbuvir-based treatment regimens: single center experience. J Med Virol. 2017;89:2181–2187.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.